Method for producing propionic acid derivative

    公开(公告)号:US11945773B2

    公开(公告)日:2024-04-02

    申请号:US17698252

    申请日:2022-03-18

    IPC分类号: C07C51/31 B01D39/06 C07C51/47

    摘要: An object of the present invention is to provide a method for producing a propionic acid derivative with high productivity. The object can be achieved by a method for producing a compound represented by formula (1):




    wherein R1 is a halogen atom or the like, R2 and R3 are each independently a hydrogen atom, a halogen atom, or an organic group, X is an oxygen atom or a sulfur atom, R4 and R5 are each independently a hydrogen atom, a halogen atom, or a hydrocarbon group optionally having one or more substituents, R6 is a hydrocarbon group optionally having one or more substituents; the method comprising step A of reacting a compound represented by formula (2):





    with a compound represented by formula (3):

    M(R1)n, wherein M is a cation, n is an integer corresponding to the valence of M, and a compound represented by formula (4):

    R6—X—H; and

    step B of separating, by filtration, the compound represented by formula (5): MFn from the mixture obtained by the above reaction.