公开(公告)号：US11795503B2

公开(公告)日：2023-10-24

申请号：US16512276

申请日：2019-07-15

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： George A. Fry ,  Christina E. Inman ,  John Bridgham ,  Timothy Hunkapiller ,  Charles S. Vann

IPC: C12Q1/6869 ,  G01N35/10 ,  B01L3/00 ,  G01N35/00 ,  G01N21/11 ,  B01F33/30 ,  B01F33/40 ,  B01J19/00 ,  C12Q1/6874 ,  G02B21/34 ,  G01N21/05

CPC classification number: C12Q1/6869 ,  B01F33/30 ,  B01F33/403 ,  B01J19/0046 ,  B01L3/50273 ,  B01L3/502715 ,  C12Q1/6874 ,  G01N21/11 ,  G01N35/00069 ,  G01N35/0099 ,  G01N35/1002 ,  B01J19/0093 ,  B01J2219/00317 ,  B01J2219/00351 ,  B01J2219/00466 ,  B01J2219/00511 ,  B01J2219/00527 ,  B01J2219/00576 ,  B01J2219/00596 ,  B01J2219/00648 ,  B01J2219/00659 ,  B01J2219/00691 ,  B01J2219/00722 ,  B01J2219/00869 ,  B01L3/5025 ,  B01L3/502707 ,  B01L2200/025 ,  B01L2200/027 ,  B01L2200/0647 ,  B01L2200/0684 ,  B01L2200/16 ,  B01L2300/0819 ,  B01L2300/0822 ,  B01L2300/0851 ,  B01L2300/0867 ,  B01L2300/0877 ,  B01L2300/0887 ,  B01L2300/1822 ,  B01L2400/0427 ,  G01N21/05 ,  G01N35/1011 ,  G01N35/1097 ,  G01N2035/00148 ,  G01N2035/00237 ,  G01N2035/1034 ,  G02B21/34 ,  Y10T436/11 ,  Y10T436/143333

Abstract: According to various embodiments, a method is provided that comprises washing an array of DNA-coated beads on a substrate, with a wash solution to remove stacked beads from the substrate. The wash solution can include inert solid beads in a carrier. The DNA-coated beads can have an average diameter and the solid beads in the wash solution can have an average diameter that is at least twice the diameter of the DNA-coated beads. The washing can form dislodged DNA-coated beads and a monolayer of DNA-coated beads. In some embodiments, first beads for forming an array are contacted with a poly(ethylene glycol) (PEG) solution comprising a PEG having a molecular weight of about 350 Da or less. In some embodiments, slides for forming bead arrays are provided as are systems for imaging the same.

公开(公告)号：US12011699B2

公开(公告)日：2024-06-18

申请号：US17252322

申请日：2018-12-19

Applicant: M AND M PRODUCTIONS KFT.

Inventor： Gábor Megyeri

IPC: B01F33/40 ,  B01F31/20 ,  B01F33/84 ,  B01F35/83 ,  B01F101/35

CPC classification number: B01F33/403 ,  B01F31/20 ,  B01F33/846 ,  B01F35/83 ,  B01F2101/35

Abstract: A mixing apparatus for mixing fluids, in particular inks of different colours for fountain pens, the mixing apparatus comprising containers (12a-12d), each adapted for storing a fluid, a tube element (13a-13e), for each container (12a-12d), connected to the container (12a-12d) and having a dispensing end portion at its end being opposite the container (12a-12d), a fluid feed device adapted for dispensing fluid from the containers (12a-12d) via the dispensing end portions, and a mixing space part encasing element (45) having a mixing space part in its inner space, the dispensing end portions of the tube elements (13a-13e) are arranged to extend into the mixing space part, and a filling unit (10) having a base portion (44) and a neck portion (40) adapted for holding the mixing space part encasing element (45), and the base portion (44) and the neck portion (40) are configured to be movable relative to each other, and are adapted for encompassing a container (25) being connectible to the fluid discharge portion. The invention is furthermore a mixing system for mixing fluids comprising a data entry unit (200), a control unit, and the mixing apparatus. The invention is furthermore a fountain pen (100) comprising a container (25) adapted for storing ink which is filled up applying the mixing apparatus.

公开(公告)号：US11958028B2

公开(公告)日：2024-04-16

申请号：US17405096

申请日：2021-08-18

Applicant: DENSO TEN Limited

Inventor： Hisaki Hayashi

IPC: B01F35/22 ,  B01F23/40 ,  B01F33/40 ,  B01F35/10 ,  B01F35/21 ,  B01F35/221 ,  B01F35/71 ,  B01F23/47

CPC classification number: B01F35/2209 ,  B01F23/405 ,  B01F33/403 ,  B01F35/1452 ,  B01F35/2112 ,  B01F35/2115 ,  B01F35/2136 ,  B01F35/22162 ,  B01F35/2217 ,  B01F35/71805 ,  B01F23/471

Abstract: A preparation apparatus includes a first tank, a second tank, a preparation tank, and a computer having a hardware processor. The first tank contains a first liquid. The second tank contains a second liquid having a lower viscosity than the first liquid. The preparation tank stirs the first liquid supplied from the first tank and the second liquid supplied from the second tank to prepare a preparation liquid. The hardware processor measures a viscosity of the first liquid based on a supply time required to supply a specified amount of the first liquid at a constant pressure from the first tank to the preparation tank, and supplies an amount of the second liquid to the preparation tank based on the measured viscosity of the first liquid so as to cause the preparation liquid to have a target viscosity.