公开(公告)号：US20240336527A1

公开(公告)日：2024-10-10

申请号：US18744627

申请日：2024-06-15

申请人： Biomason Inc.

发明人： Kent J. Smith ,  Cameron Arnette ,  Ginger K. Dosier ,  J. Michael Dosier

IPC分类号： C04B20/10 ,  B05D1/02 ,  C04B12/00 ,  C04B28/10 ,  C04B103/00 ,  C04B111/00 ,  C04B111/60 ,  C12N11/02 ,  C12N11/14 ,  C12P3/00

CPC分类号： C04B20/1092 ,  B05D1/02 ,  C04B12/00 ,  C04B28/10 ,  C12N11/02 ,  C12N11/14 ,  C12P3/00 ,  C12Y305/01005 ,  C04B2103/0001 ,  C04B2103/0075 ,  C04B2111/00146 ,  C04B2111/60 ,  Y02W30/91

摘要： Compositions, tools and methods for the manufacture of construction materials, masonry, solid structures and compositions to facilitate dust control are described. Compositions and methods for the manufacture of pigmented solids structures for which can be used for construction and/or decoration are also described. Manufacturing comprises fixing one or more pigments to an aggregate material such as crushed rock, stone or sand. The pigmented aggregate is incubated with urease or urease producing microorganisms, an amount of a nitrogen source such as urea, and an amount of calcium source such as calcium chloride forming calcite bridges between particles of aggregate. Using selected aggregate and pigment, the process also provides for the manufacture of simulated-stone materials such as clay or granite bricks or blocks, marble counter-tops, and more. Compositions containing microorganisms and pigment as kits that can be added to most any aggregate materials are also described.

公开(公告)号：US20240167014A1

公开(公告)日：2024-05-23

申请号：US18548909

申请日：2022-03-04

申请人： NEXTKIDNEY S.A. ,  Dialyss Pte Ltd

发明人： Harmen Henri Jacobus De Jongh ,  Jacobus Adrianus Wilhelmus Jong ,  Christian Gert Bluechel

IPC分类号： C12N9/80 ,  C12N9/96

CPC分类号： C12N9/80 ,  C12N9/96 ,  C12Y305/01005

摘要： The present invention relates to methods and compositions that are useful for improving the stability of an enzyme, for instance during storage. Using the methods and compositions of the invention, enzyme activity is preserved over time, allowing longer storage.

公开(公告)号：US11987741B2

公开(公告)日：2024-05-21

申请号：US17192337

申请日：2021-03-04

申请人： ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

发明人： Edward Kavazanjian ,  Nasser Hamdan ,  Hamed Khodadadi Tirkolaei ,  Abdullah Almajed

IPC分类号： C09K17/44 ,  C04B24/14 ,  C04B28/00 ,  C04B103/00 ,  C04B111/00 ,  E02D3/12

CPC分类号： C09K17/44 ,  C04B24/14 ,  C04B28/003 ,  E02D3/12 ,  C04B2103/0001 ,  C04B2111/00732 ,  C12Y305/01005 ,  E02D2300/0025 ,  E02D2300/0045

摘要： The present disclosure provides a method of biocementation comprising contacting a granular, cohesionless soil with a solution, wherein the solution comprises urea, urease, a source of calcium ions, and a source of non-urease proteins, wherein the urea, urease, source of calcium ions, and source of non-urease proteins are provided in effective amounts suitable to cause crystallization of calcium carbonate.

公开(公告)号：US20180119185A1

公开(公告)日：2018-05-03

申请号：US15803700

申请日：2017-11-03

申请人： Arizona Board of Regents on behalf of Arizona State University

发明人： Edward Kavazanjian ,  Nasser Hamdan

IPC分类号： C12P9/00 ,  C12N9/80 ,  C12P3/00 ,  C01F11/00

CPC分类号： C12P9/00 ,  C01F11/00 ,  C04B28/10 ,  C04B2103/0001 ,  C04B2111/72 ,  C12N9/80 ,  C12P3/00 ,  C12Y305/01005

摘要： The present invention provides methods for mineral precipitation and/or cementation of permeable or fractured non-porous materials using isolated urease.

公开(公告)号：US20180112163A1

公开(公告)日：2018-04-26

申请号：US15794048

申请日：2017-10-26

申请人： Jiangnan University

发明人： Fang Fang ,  Xia Ding ,  Qiaoyu Li ,  Fan Liu ,  Xinhu Zhou ,  Xiang Chen ,  Jian Chen ,  Guocheng Du

IPC分类号： C12G3/08 ,  C12N1/20 ,  C12N9/54 ,  C12R1/07

CPC分类号： C12G3/08 ,  C12N1/20 ,  C12N9/54 ,  C12R1/07 ,  C12Y305/01005

摘要： The present invention a method for simultaneously reducing urethane and its precursors levels during Chinese liquor production process, which relates to the field of fermented food production. The present invention is carried out through inoculating Bacillus amyloliquefaciens JP21 or combines with urease into the grains for fermentation. The content of EC and urea in the fermented grains after 5-day fermentation could reduce 30.16% and 50.05% respectively, With an addition of the B. amyloliquefaciens during grains fermentation, EC and urea levels are successfully controlled, and at the same time aroma and tastes of Chinese liquor hasn't been affected.

公开(公告)号：US20160264463A1

公开(公告)日：2016-09-15

申请号：US15066692

申请日：2016-03-10

申请人： BioMason, Inc.

发明人： Ginger K. Dosier ,  Victoria M. Durham ,  Thomas A. Hill ,  J. Michael Dosier ,  Steven W. McAllister

IPC分类号： C04B14/28 ,  B28B1/14 ,  C12N11/02 ,  B05D1/02 ,  C09K3/22 ,  C12N11/14

CPC分类号： B05D1/02 ,  C04B12/00 ,  C04B28/10 ,  C04B2103/0001 ,  C04B2103/0075 ,  C04B2111/00146 ,  C04B2111/60 ,  C12N11/02 ,  C12N11/14 ,  C12Y305/01005 ,  Y02W30/96 ,  Y02W30/97 ,  C04B14/04 ,  C04B14/22 ,  C04B14/34 ,  C04B18/20 ,  C04B18/241 ,  C04B18/26 ,  C04B38/10

摘要： Compositions and methods for producing materials for construction and for dust control utilizing enzyme producing cells, an amount of a nitrogen source such as urea, and an amount of calcium such as calcium chloride. Calcium contributes to the formation of calcium carbonate which creates a solid structure, layer or shield. Compositions of the invention can be sprayed or otherwise applied to surfaces for erosion control, foundation support, prevention of sink hole formation or other applications. Ammonia, water and other by-products of the process can be recycled and re-utilized for the same or other purposes including, for example, as fertilizers and energy sources, or independently fermented from selectively cultivated microorganisms.

摘要翻译： 用于生产施用材料和利用酶产生细胞的粉尘控制的组合物和方法，氮源如尿素的量以及钙如氯化钙的量。 钙有助于形成碳酸钙，产生固体结构，层或屏蔽。 本发明的组合物可以喷涂或以其他方式施加到表面用于侵蚀控制，基础支撑，防止沉孔形成或其它应用。 该方法的氨，水和其它副产物可以用于相同或其他目的，例如作为肥料和能源，或独立地从选择性栽培的微生物中发酵而再利用和再利用。

公开(公告)号：US09428418B2

公开(公告)日：2016-08-30

申请号：US14939118

申请日：2015-11-12

申请人： BioMason, Inc.

发明人： Ginger K. Dosier

IPC分类号： C04B24/12 ,  C04B28/10 ,  C04B40/00 ,  C04B24/14 ,  C04B35/632 ,  C12P1/04 ,  C04B103/00

CPC分类号： C04B24/14 ,  C04B14/305 ,  C04B24/12 ,  C04B28/10 ,  C04B35/632 ,  C04B40/0039 ,  C04B2103/0001 ,  C04B2103/0067 ,  C04B2111/00017 ,  C12N9/80 ,  C12P1/04 ,  C12Y305/01005 ,  C04B14/06 ,  C04B22/124 ,  C04B24/126

摘要： Methods for producing construction material utilizing loose pieces of aggregate (30), enzyme producing bacteria, an amount of urea and an amount of calcium ions. A first solution is prepared which includes urease which is formed by enzyme producing bacteria. A second solution is prepared which includes urea and calcium ions. The first and second solutions are added to the loose aggregate (30). The calcium ions contribute to the formation of calcium carbonate wherein the calcium carbonate fills and bonds between at least some of the gaps between the loose pieces of aggregate forming a solid construction material (92).

摘要翻译： 使用松散的骨料（30），酶产生细菌，一定量的尿素和一定量的钙离子来生产建筑材料的方法。 制备第一种溶液，其包括由酶产生细菌形成的脲酶。 制备了包括尿素和钙离子的第二种溶液。 将第一和第二溶液加入松散骨料（30）中。 钙离子有助于碳酸钙的形成，其中碳酸钙填充并粘结在形成固体结构材料（92）的松散骨料块之间的至少一些间隙之间。

公开(公告)号：US08945585B2

公开(公告)日：2015-02-03

申请号：US13516733

申请日：2011-08-29

申请人： Baoning Wang

发明人： Baoning Wang

IPC分类号： A61K39/02 ,  A61K39/00 ,  C07H21/04 ,  C07K14/205 ,  C07K14/245

CPC分类号： C07K14/205 ,  A61K39/02 ,  A61K39/105 ,  C07K14/245 ,  C07K2319/00 ,  C12N9/80 ,  C12Y305/01005

摘要： The present invention discloses a multi-target recombination gene and the application of its protein to prevent and cure Helicobacter pylori. It includes a multi-target fusion polypeptide having amino acid sequence shown in SEQ ID NO:2, a multi-target recombination gene of encoding multi-target fusion polypeptide having nucleotide sequence shown in SEQ ID NO:1, and the application of the multi-target recombination gene or the multi-target fusion polypeptide or specific antibody of the multi-target fusion polypeptide as biological products for preventing and curing Helicobacter pylori. The present invention effectively combines the key target protein UreI for Hp gastric colonization, and antigen target of UreB to create the best drug target.

摘要翻译： 本发明公开了一种多靶点重组基因及其蛋白质在预防和治疗幽门螺杆菌中的应用。 它包括具有SEQ ID NO：2所示氨基酸序列的多靶融合多肽，编码具有SEQ ID NO：1所示核苷酸序列的多靶融合多肽的多靶基因重组基因， 靶标重组基因或多靶融合多肽或多靶融合多肽的特异性抗体作为预防和治疗幽门螺杆菌的生物制品。 本发明有效地结合了Hp胃定植的关键靶蛋白UreI和UreB的抗原靶点，创造了最佳的药物靶点。

公开(公告)号：US08268604B2

公开(公告)日：2012-09-18

申请号：US11961498

申请日：2007-12-20

申请人： Gordon Bruce Collier ,  Jason Andrew Macleod ,  Anjulia Wong ,  Attila Csaba Nemeth

发明人： Gordon Bruce Collier ,  Jason Andrew Macleod ,  Anjulia Wong ,  Attila Csaba Nemeth

IPC分类号： C12N9/96

CPC分类号： C12Q1/005 ,  C12N11/08 ,  C12Y305/01005

摘要： The invention is directed to enzyme immobilization compositions comprising: one or more enzymes, a humectant, an acrylic-based monomer, a water-soluble organic photo-initiator and a water-soluble acrylic-based cross-linker in a substantially homogeneous aqueous mixture. The invention is also directed to methods for forming sensors comprising such compositions and to apparati for forming arrays of immobilized layers on an array of sensors by dispensing such compositions onto a substrate.

摘要翻译： 本发明涉及酶固定组合物，其包含：在基本上均匀的含水混合物中的一种或多种酶，湿润剂，丙烯酸类单体，水溶性有机光引发剂和水溶性丙烯酸类交联剂。 本发明还涉及用于形成包含这种组合物的传感器的方法，并且通过将这样的组合物分配到基底上来设置在传感器阵列上形成固定化层的阵列。

公开(公告)号：US20170246627A1

公开(公告)日：2017-08-31

申请号：US15506435

申请日：2015-08-31

申请人： Siemens Healthcare Diagnostics Inc.

发明人： John Perng

IPC分类号： B01L3/00 ,  C12Q1/54 ,  C12Q1/40 ,  C12Q1/58 ,  C12Q1/34 ,  C12Q1/26

CPC分类号： B01L3/5027 ,  B01L3/502707 ,  B01L3/50273 ,  B01L2200/0621 ,  B01L2300/0816 ,  B01L2300/0851 ,  B01L2300/0864 ,  B01L2300/0887 ,  B01L2300/165 ,  B01L2400/0406 ,  C12Q1/25 ,  C12Q1/26 ,  C12Q1/34 ,  C12Q1/40 ,  C12Q1/54 ,  C12Q1/58 ,  C12Y101/03004 ,  C12Y113/12004 ,  C12Y302/01108 ,  C12Y305/01005 ,  C12Y305/0201 ,  C12Y305/03003 ,  G01N27/447

摘要： A diagnostic device 10 for screening for a target analyte in a sample is provided. The diagnostic device 10 comprises a substrate 12 and a hydrophobic material 20 disposed on the substrate. The hydrophobic material 20 is selected to be converted from the hydrophobic material 20 to a hydrophilic material 22 upon contact with a conversion component within or derived from a sample introduced to the device 10.