利索-全球专利检索

  1. Login
  2. Sign Up

Search Results

131 records (took 0.021 seconds)

    ABSORPTION METHOD FOR ENTRAPMENT OF DRUGS IN POLYMERIC NANOPARTICLES
    4.
    发明申请
    ABSORPTION METHOD FOR ENTRAPMENT OF DRUGS IN POLYMERIC NANOPARTICLES 审中-公开
    用于在聚合物纳米颗粒中形成药物的吸收方法

    公开(公告)号：US20130149381A1

    公开(公告)日：2013-06-13

    申请号：US13708825

    申请日：2012-12-07

    Applicant: Centro De Investigacion En Quimica Aplicada

    Inventor： Raúl Guillermo López Campos ,  Hened Saade Caballero

    IPC: A61K9/51

    CPC classification number: A61K9/5192 ,  A61K9/5123 ,  A61K9/5138 ,  B82Y5/00 ,  Y10S977/773 ,  Y10S977/897 ,  Y10S977/906

    Abstract: A method for preparing polymeric nanoparticles having entrapped active ingredients or drugs, the method includes the step of preparing a reaction by mixturing water, a surfactant, and a water-soluble radical initiator; polymerizing a polymerizable monomer in the reaction to obtain a dispersion of polymeric nanoparticles having a controlled size with average diameters smaller than 50 nm; dissolving one or more active ingredients in a suitable solvent; adding the solution of active ingredients to the dispersion of polymeric nanoparticles and allowing that the active ingredients to become entrapped within polymeric nanoparticles; and evaporating the dispersion of polymeric nanoparticles having entrapped active ingredients to evaporate the residual monomer and the solvent used as a vehicle for loading the active ingredient.

    Abstract translation: 一种制备具有捕获的活性成分或药物的聚合物纳米颗粒的方法，该方法包括通过混合水，表面活性剂和水溶性自由基引发剂来制备反应的步骤; 在反应中聚合可聚合单体以获得具有平均直径小于50nm的受控尺寸的聚合物纳米颗粒的分散体; 将一种或多种活性成分溶解在合适的溶剂中; 将活性成分溶液加入到聚合物纳米颗粒的分散体中，并允许活性成分被截留在聚合物纳米颗粒内; 并蒸发具有捕获的活性成分的聚合物纳米颗粒的分散体，以蒸发残留的单体和用作装载活性成分的载体的溶剂。

    Aqueous dispersion of hydrogel nanoparticles with inverse thermoreversible gelation
    5.
    发明授权
    Aqueous dispersion of hydrogel nanoparticles with inverse thermoreversible gelation 失效
    具有逆热反应凝胶化的水凝胶纳米颗粒的水分散体

    公开(公告)号：US08048450B2

    公开(公告)日：2011-11-01

    申请号：US10581678

    申请日：2004-12-09

    Applicant: Zhibing Hu ,  Xiaohu Xia

    Inventor： Zhibing Hu ,  Xiaohu Xia

    IPC: A61K9/14

    CPC classification number: A61K9/0024 ,  A61K9/06 ,  A61K9/10 ,  A61K9/1635 ,  A61K9/5138 ,  A61K9/5161 ,  A61K9/5192 ,  Y10S977/702 ,  Y10S977/897 ,  Y10S977/906

    Abstract: An aqueous dispersion of hydrogel nanoparticles and methods of making the aqueous dispersion of hydrogel nanoparticles having an interpenetrating polymer network (“IPN”) are described. The uniformed sized mono-disperse IPN nanoparticles have inverse thermo gelation properties that allow therapeutic medications to be uniformly distributed in a liquid form of the aqueous dispersion of hydrogel nanoparticles. Such medications can then be released from a solid form of the aqueous dispersion of hydrogel nanoparticles in time dependant manor.

    Abstract translation: 描述了水凝胶纳米颗粒的水分散体和制备具有互穿聚合物网络（“IPN”）的水凝胶纳米颗粒的水分散体的方法。 均匀尺寸的单分散IPN纳米颗粒具有逆热凝胶化性质，其允许治疗性药物均匀分布在液体形式的水凝胶纳米颗粒的水分散体中。 然后可以从固体形式的时间依赖性的水凝胶纳米颗粒的水分散体中释放这些药物。

    Nanoparticle-polymer bistable devices
    6.
    发明授权
    Nanoparticle-polymer bistable devices 有权
    纳米颗粒聚合物双稳态器件

    公开(公告)号：US07554111B2

    公开(公告)日：2009-06-30

    申请号：US11131980

    申请日：2005-05-18

    Applicant: Yang Yang ,  Richard Kaner

    Inventor： Yang Yang ,  Richard Kaner

    IPC: H01L35/24

    CPC classification number: G11C13/0014 ,  B82Y10/00 ,  G11C13/0016 ,  Y10S977/81 ,  Y10S977/897 ,  Y10S977/943

    Abstract: A bistable electrical device employing a bistable polymer body made from an electrically insulating polymer material in which doped nanofibers are dispersed. The doped nanofibers are composed of an electrically conductive nanofiber material and electrically conductive nanoparticles. The doped nanofibers impart bistable electrical characteristics to the polymer body, such that the polymer body is reversibly convertible between a low resistance state and a high resistance state by application of an electrical voltage.

    Abstract translation: 一种双稳态电气装置，其采用由掺杂纳米纤维分散的电绝缘聚合物材料制成的双稳态聚合物体。 掺杂的纳米纤维由导电纳米纤维材料和导电纳米颗粒组成。 掺杂的纳米纤维向聚合物体赋予双稳态电特性，使得聚合物体通过施加电压在低电阻状态和高电阻状态之间可逆地转换。

    SURFACE AND SITE-SPECIFIC POLYMERIZATION BY DIRECT-WRITE LITHOGRAPHY
    8.
    发明申请
    SURFACE AND SITE-SPECIFIC POLYMERIZATION BY DIRECT-WRITE LITHOGRAPHY 失效
    通过直写写地图的表面和位点特异性聚合

    公开(公告)号：US20080167202A1

    公开(公告)日：2008-07-10

    申请号：US11966764

    申请日：2007-12-28

    Applicant: Chad A. Mirkin ,  Xiaogang Liu ,  Shouwu Guo

    Inventor： Chad A. Mirkin ,  Xiaogang Liu ,  Shouwu Guo

    IPC: C40B40/14 ,  B05D5/00

    CPC classification number: G03F7/0002 ,  G01Q80/00 ,  G03F7/2049 ,  H01J2237/31738 ,  Y10S977/857 ,  Y10S977/882 ,  Y10S977/897

    Abstract: Polymeric microstructures and nanostructures can be prepared with use of a tip to pattern a surface. A tip can be used to pattern a structure which can initiate polymerization. The structure can be then exposed to monomer to induce polymerization at the structure. Alternatively, a tip can be used to pattern a surface with a monomer in which the surface is treated with polymerization catalyst so that polymerization occurs at the patterning site. Ring-opening metathesis polymerization can be carried out with use of the tip to control the polymerization. The tip can be a sharp tip as used in for example an atomic force microscope tip. Norbornene types of monomers can be used. Biological macromolecules can be also prepared.

    Abstract translation: 可以使用尖端来制备聚合物微结构和纳米结构以对表面进行图案化。 尖端可用于图案化可引发聚合的结构。 然后将该结构暴露于单体以在结构处引发聚合。 或者，可以使用尖端来用表面用聚合催化剂处理的单体对表面进行图案化，使得在图案化位点发生聚合。 可以使用尖端进行开环易位聚合以控制聚合。 尖端可以是例如原子力显微镜尖端中使用的尖锐尖端。 可以使用降冰片烯类型的单体。 还可制备生物大分子。

    Step and flash imprint lithography
    9.
    发明申请
    Step and flash imprint lithography 审中-公开
    步进和闪光刻印光刻

    公开(公告)号：US20050236739A1

    公开(公告)日：2005-10-27

    申请号：US11062420

    申请日：2005-02-22

    Applicant: Carlton Willson ,  Matthew Colburn

    Inventor： Carlton Willson ,  Matthew Colburn

    IPC: G03F7/038 ,  B29C31/00 ,  B81C1/00 ,  G03F7/00 ,  H01L21/027 ,  H01L21/30 ,  H01L21/302 ,  H01L21/3065 ,  H05K3/06

    CPC classification number: B82Y10/00 ,  B29C43/003 ,  B29C43/021 ,  B29C2043/025 ,  B82Y40/00 ,  G03F7/0002 ,  H05K3/061 ,  Y10S977/887 ,  Y10S977/897

    Abstract: A method of forming a relief image in a structure comprising a substrate and a transfer layer formed thereon comprises covering the transfer layer with a polymerizable fluid composition, and then contacting the polymerizable fluid composition with a mold having a relief structure formed therein such that the polymerizable fluid composition fills the relief structure in the mold. The polymerizable fluid composition is subjected to conditions to polymerize polymerizable fluid composition and form a solidified polymeric material therefrom on the transfer layer. The mold is then separated from the solid polymeric material such that a replica of the relief structure in the mold is formed in the solidified polymeric material; and the transfer layer and the solidified polymeric material are subjected to an environment to selectively etch the transfer layer relative to the solidified polymeric material such that a relief image is formed in the transfer layer.

    Abstract translation: 在包括基板和形成在其上的转印层的结构中形成浮雕图像的方法包括用可聚合流体组合物覆盖转印层，然后使可聚合流体组合物与其中形成有浮雕结构的模具接触，使得可聚合的 流体组合物填充模具中的浮雕结构。 可聚合流体组合物经受聚合可聚合流体组合物并在转移层上形成固化的聚合物材料的条件。 然后将模具与固体聚合物材料分离，使得在固化的聚合物材料中形成模具中的浮雕结构的复制品; 并且转印层和固化的聚合物材料经受环境以相对于固化的聚合物材料选择性地蚀刻转印层，使得在转印层中形成浮雕图像。

    Polymeric and carbon compositions with metal nanoparticles
    10.
    发明授权
    Polymeric and carbon compositions with metal nanoparticles 有权
    具有金属纳米粒子的聚合物和碳组成

    公开(公告)号：US06890504B2

    公开(公告)日：2005-05-10

    申请号：US10652081

    申请日：2003-08-28

    Applicant: Teddy M. Keller ,  Syed B. Qadri

    Inventor： Teddy M. Keller ,  Syed B. Qadri

    IPC: D01F9/127 ,  C01B31/34 ,  B01J23/00 ,  C07F15/00

    CPC classification number: B82Y30/00 ,  D01F9/127 ,  Y10S977/773 ,  Y10S977/775 ,  Y10S977/777 ,  Y10S977/788 ,  Y10S977/896 ,  Y10S977/897

    Abstract: The invention comprises a chemical composition with the structure shown below. The composition can be polymerized or pyrolyzed, forming transition metal nanoparticles homogeneously dispersed in a thermoset or carbon composition. The size of the nanoparticles can be controlled by manipulating the number and arrangement of functional groups in the composition and by changing the conditions of the polymerization or pyrolysis. The resulting thermosets and carbon compositions have useful magnetic, electric, mechanical, catalytic and/or optical properties. wherein A is selected from the group consisting of H, wherein M is a metal selected independently from the group consisting of Fe, Mn, Ru, Co, Ni, Cr and V; wherein Rx is independently selected from the group consisting of an aromatic, a substituted aromatic group and combinations thereof; wherein Ry is independently selected from the group consisting of an aromatic, a substituted aromatic group and combinations thereof; wherein m is ≧0; wherein s is ≧0; wherein z is ≧0; and wherein m and s are independently determined in each repeating unit.

    Abstract translation: 本发明包括具有如下结构的化学组合物。 组合物可以聚合或热解，形成均匀分散在热固性或碳组合物中的过渡金属纳米颗粒。 可以通过操纵组合物中官能团的数目和排列以及通过改变聚合或热解的条件来控制纳米颗粒的尺寸。 所得的热固性和碳组合物具有有用的磁性，电学，机械，催化和/或光学性质。 其中A选自H，其中M是独立选自Fe，Mn，Ru，Co，Ni，Cr和V的金属; 其中Rx独立地选自芳族，取代的芳族基团及其组合; 其中R y独立地选自芳族，取代的芳族基团及其组合; 其中m是> = 0; 其中s为> = 0; 其中z是> = 0; 并且其中m和s在每个重复单元中独立地确定。

Patent Agency Ranking