Titanium dioxide nanotubes for production and delivery of nitric oxide and methods for production thereof
    6.
    发明授权
    Titanium dioxide nanotubes for production and delivery of nitric oxide and methods for production thereof 有权
    用于生产和输送一氧化氮的二氧化钛纳米管及其生产方法

    公开(公告)号:US09278113B2

    公开(公告)日:2016-03-08

    申请号:US12750403

    申请日:2010-03-30

    摘要: The present disclosure describes compositions operable for releasing nitric oxide under photochemical conditions. The compositions include a titanium dioxide nanomaterial and a nitric oxide-releasing compound deposited on the titanium dioxide nanomaterial that is operable to release nitric oxide under photochemical conditions. Titanium dioxide nanomaterials include, for example, titanium dioxide nanotubes. To facilitate the photochemical release of nitric oxide, some embodiments of the compositions further include a semiconductor that is deposited on the titanium dioxide nanotubes. Both the semiconductor and the nitric oxide-releasing compound may be deposited on the interior surface, exterior surface, or both of the titanium dioxide nanotubes. A polymer may wrap the titanium dioxide nanotubes to protect the nitric oxide-releasing compounds from moisture. Also disclosed herein are methods for producing such compositions and medical devices obtained therefrom.

    摘要翻译: 本公开描述了可用于在光化学条件下释放一氧化氮的组合物。 组合物包括沉积在二氧化钛纳米材料上的二氧化钛纳米材料和一氧化氮释放化合物,其可操作以在光化学条件下释放一氧化氮。 二氧化钛纳米材料包括例如二氧化钛纳米管。 为了促进一氧化氮的光化学释放,组合物的一些实施方案还包括沉积在二氧化钛纳米管上的半导体。 半导体和一氧化氮释放化合物都可以沉积在二氧化钛纳米管的内表面,外表面或两者上。 聚合物可以包裹二氧化钛纳米管以保护释放一氧化氮的化合物免受湿气侵害。 本文还公开了用于制备由此获得的组合物和医疗装置的方法。