Abstract:
The present invention provides modular microfluidic devices and systems, as well as methods for their manufacture. A microfluidic device is provided comprising first and second substrates (59, 60), and at least one stencil (58) sandwiched between the first and second substrates so as to define one or more sealed microstructures therebetween. The stencil is adhered to at least one of the first and second substrates by an adhesive (44). In a preferred embodiment, there is a plurality of sandwiched stencils. Also, the first and second substrates are preferably substantially planar. These microfluidic devices can be rapidly prototyped with low tool-up cost, and can be easily assembled to form three-dimensional structures having complex microfluidic system geometries.
Abstract:
Microchip devices are provided which include a substrate having a plurality of reservoirs containing a secondary device, a reacting component, or a combination thereof. At least one barrier layer covers each reservoir to isolate the reservoir contents from one or more environmental components outside the reservoirs. The barrier layer can be selectively disintegrated or permeabilized to expose the isolated contents to the one or more environmental components. The secondary device preferably includes a sensor or sensing component, for example, a biosensor, or a light detection or imaging device, such as an optical fiber. Preferred reacting components include catalyst and reagent, which may be immobilized in the reservoirs.
Abstract:
The disclosure concerns methods comprising forming a phenol and acetone mixture from decomposition of a cumene hydroperoxide or a phenol, acetone, and AMS from the decomposition of a mixture containing dicumyl peroxide in a system comprising one or more reactors where at least a portion of an inner surface of the one or more reactors has a polymer coating and wherein the coating inhibits build-up of a fouling precipitate on the coated inner surface of the one or more reactors as compared to such build-up in the absence of the coating.
Abstract:
The present invention is an apparatus for providing a linear temperature gradient to an architecture suitable for massively parallel chemical or biochemical processing. The architecture is disposed on a substrate. The apparatus uses two temperature elements disposed essentially parallel to each other and in thermal contact with the substrate. When the temperature elements are held at different temperatures, a linear temperature gradient is formed in the substrate.
Abstract:
There is disclosed a method providing micro-scale devices, nano-scale devices, or devices having both nano-scale and micro-scale features. The method of the invention comprises fluidic assembly and various novel devices produced thereby. A variety of nanofluidic and molecular electronic type devices and structures having applications such as filtering and genetic sequencing are provided by the invention
Abstract:
A microfluidic device adapted such that the flow of fluids within the device is controlled by different surfaces of the device having different surface characteristics. Preferably the device comprises a substrate not formed from a hydrated oxide material.
Abstract:
Aus einem Stapel von Folien oder Platten (F) aufgebauter Wärmetauscher (1), insbesondere Mikrowärmetauscher, wobei in den einzelnen Platten (F) Durchbrüche (4, 5, 7, 8) und in der Plattenebene verlaufende Kanäle (2, 3) ausgebildet und die Platten (F) so übereinander angeordnet sind, dass sich die Kanäle (2, 3) in aufeinander folgenden Platten (F) kreuzen, ein erstes Fluid (P) durch die Kanäle (2) einer Platte (F) und ein zweites Fluid (W) durch die Kanäle (3) in der benachbarten Platte (F) strömt, an den Außenseiten des sich ergebenden Blocks von sich kreuzenden Kanälen (2, 3) Zuführ- und Abführleitungen durch die Durchbrüche (4, 5, 7, 8) ausgebildet sind, und wobei zumindest eines der beiden Fluide (P,W) antiparallel bzw. abwechselnd in Gegenrichtung durch die Kanäle der betreffenden Platte strömt.
Abstract:
This invention relates to a process for converting ethylene to ethylene oxide comprising: flowing reactants comprising ethylene and oxygen or a source of oxygen in a microchannel reactor in contact with a catalyst to form a product comprising ethylene oxide, the reactants undergoing an exothermic reaction in the microchannel reactor; and transferring heat from the microchannel reactor to a heat exchanger.