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    DUAL EMISSION FLUORESCENT COMPOUNDS
    1.
    发明申请
    DUAL EMISSION FLUORESCENT COMPOUNDS 审中-公开
    双发射荧光化合物

    公开(公告)号：WO2017147646A1

    公开(公告)日：2017-09-08

    申请号：PCT/AU2017/050170

    申请日：2017-02-28

    申请人： MACQUARIE UNIVERSITY

    发明人： KARUSO, Peter ,  CHATTERJEE, Soumit

    IPC分类号： C07D263/22 ,  C07D233/06 ,  C07C233/76 ,  C07C231/10

    CPC分类号： C07C231/10 ,  C07C231/14 ,  C07C233/85 ,  C07D233/96 ,  C07D263/42 ,  C07D403/04 ,  C07D405/04 ,  C07C211/10

    摘要： The invention relates to a dual emission fluorescent compound comprising a chromophore suitable for exhibiting an emission at a first wavelength from an excited state; wherein the compound further comprises one or more groups suitable for inducing a structural rearrangement in the molecule on formation of the excited state, wherein the structural rearrangement stabilises at least a second electromagnetic emission at a second wavelength, such that dual emission is observable at room temperature. Such dual emission allows for the super sensitive ratiometric quantification of analytes.

    摘要翻译： 本发明涉及一种双发射荧光化合物，其包含适合于从激发态显示第一波长发射的发色团; 其中所述化合物还包含一个或多个适于在形成激发态时引起分子中的结构重排的基团，其中所述结构重排稳定至少第二波长的第二电磁发射，使得双重发射在室温下可观察到 。 这种双重发射允许对分析物进行超敏感的比率定量分析。

    AROMATIC IMIDAZOLIDINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASES OF BACTERIAL NATURE
    2.
    发明申请
    AROMATIC IMIDAZOLIDINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASES OF BACTERIAL NATURE 审中-公开
    芳香咪唑啉酮衍生物及其在治疗细菌性疾病中的应用

    公开(公告)号：WO2013151450A1

    公开(公告)日：2013-10-10

    申请号：PCT/PL2013/000044

    申请日：2013-04-02

    申请人： UNIWERSYTET JAGIELLOŃSKI

    发明人： HANDZLIK, Jadwiga ,  KIEĆ-KONONOWICZ, Katarzyna ,  OTRĘBSKA, Ewa ,  KALETA, Maria

    IPC分类号： C07D233/96 ,  C07D409/06 ,  A61K31/4178 ,  A61P31/00

    CPC分类号： C07D233/96 ,  C07D409/06

    摘要： The invention introduces new derivatives of aromatic imidazolidinones, which fall within the scope of the general formula I and their pharmaceutical forms of suitable additive salts with acids, wherein R 1 and R 2 are as defined herein, in particular for the prevention or treatment of diseases of bacterial nature. The invention further introduces the use of compounds according to the invention for the manufacture of a medication useful for the treatment of various conditions as described above.

    摘要翻译： 本发明引入芳族咪唑烷酮的新衍生物，它们属于通式I的范围内，以及它们与酸的合适添加剂的药物形式，其中R 1和R 2如本文所定义，特别是用于预防或治疗细菌性疾病 性质。 本发明进一步介绍了根据本发明的化合物在制备用于治疗如上所述的各种病症的药物中的用途。

    NEW HETEROCYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYES AND PIGMENTS
    9.
    发明申请
    NEW HETEROCYCLIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYES AND PIGMENTS 审中-公开
    新的杂环化合物，其制备方法及其用作染料和颜料

    公开(公告)号：WO2004089941A1

    公开(公告)日：2004-10-21

    申请号：PCT/EP2004/050276

    申请日：2004-03-10

    申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. ,  ADAM, Jean-Marie ,  DALVI, Pramod V. ,  EKKUNDI, Vadiraj Subbanna ,  BACHER, Jean-Pierre ,  SREENIVASAN, Ramaswami ,  RANE, Deepak M.

    发明人： ADAM, Jean-Marie ,  DALVI, Pramod V. ,  EKKUNDI, Vadiraj Subbanna ,  BACHER, Jean-Pierre ,  SREENIVASAN, Ramaswami ,  RANE, Deepak M.

    IPC分类号： C07D407/04

    CPC分类号： C07D207/44 ,  C07D233/96 ,  C07D263/40 ,  C07D307/34

    摘要： Compounds of formula (I) wherein R 1 is hydrogen, hydroxy, halogen, nitro, cyano, amino, carboxy, carboxylic ester, sulfo, sulfonic ester, carboxylic amide, sulfonic amide, alkylthio, arylthio, alkoxy or aryloxy, R' 1 is hydrogen, hydroxy, halogen, nitro, cyano, amino, carboxy, carboxylic ester, sulfo, sulfonic ester, carboxylic amide, sulfonic arnide, alkylthio, arylthio, alkoxy or aryloxy, X is -O-, -S-, -NH- or -N(alkyl)-, X' is -0-, -S-, -NH- or -N(alkyl)-, Y is hydrogen or carboxylic ester, Y' is hydrogen or carboxylic ester, Z is =C- or =N-, Z' is =C- or =N-, x is 0 or 1, when Z is =N-, then x is 0, y is 0 or 1, when Z' is =N-, then y is 0, A is a conjugated linking bridge of the formulae (II), (III), (IV), (V), or (VI), wherein n is 0, 1, 2 or 3, m is 0, 1, 2 or 3, B is a phenyl ring, T is =C(R 3 )- or =N-, wherein R 3 is hydrogen, C 1 -C 12 alkyl or CN, W is a heterocyclic, or linear or polycondensed aromatic group which is unsubstituted or substituted by alkyl, halogen, hydroxy, alkoxy, alkylthio or amino, G is -CH= or -N=, and R 2 is hydrogen, alkyl, halogen, hydroxy, alkoxy, alkylthio or amino, their preparation and their use in the production of coloured plastics or polymeric color particles.

    摘要翻译： R 1是氢，羟基，卤素，硝基，氰基，氨基，羧基，羧酸酯，磺基，磺酸酯，羧酸酰胺，磺酰胺，烷硫基，芳硫基，烷氧基或芳氧基的式 羟基，卤素，硝基，氰基，氨基，羧基，羧酸酯，磺基，磺酸酯，羧酸酰胺，磺酰胺，烷硫基，芳硫基，烷氧基或芳氧基，X是-O - ， - S - ， - NH-或 - N（烷基） - ，X'是-O - ， - S-，-NH-或-N（烷基） - ，Y是氢或羧酸酯，Y'是氢或羧酸酯，Z是= N，Z'= C或= N-，x为0或1，当Z为= N-时，则x为0，y为0或1，当Z'为= N-时，y为0 A是式（II），（III），（IV），（V）或（VI）的共轭连接桥，其中n为0,1,2或3，m为0,1,2或 3，B是苯环，T是=（R 3） - 或= N-，其中R 3是氢，C 1 -C 12烷基或CN，W是杂环基，或未被取代或被烷基取代的直链或缩聚芳基 ，卤素，羟基，烷氧基 ，烷硫基或氨基，G为-CH =或-N =，R2为氢，烷基，卤素，羟基，烷氧基，烷硫基或氨基，它们的制备及其在生产有色塑料或聚合物色颗粒中的应用。

    NAPHTHALENE DERIVATIVES
    10.
    发明申请
    NAPHTHALENE DERIVATIVES 审中-公开
    萘衍生物

    公开(公告)号：WO01077082A1

    公开(公告)日：2001-10-18

    申请号：PCT/JP2000/002278

    申请日：2000-04-07

    IPC分类号： A61P7/02 ,  C07D233/96 ,  A61K31/4166 ,  A61K31/4168 ,  A61K31/505 ,  A61K31/506 ,  A61K31/5377 ,  C07D233/34 ,  C07D233/36 ,  C07D233/42 ,  C07D239/26 ,  C07D239/30 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12

    CPC分类号： C07D233/96

    摘要： Naphthalene derivatives represented by the general formula (1), which exhibit an excellent fibrinolysis accelerating effect and are useful as orally administrable antithrombotic or thrombolytic drugs wherein R1 is hydrogen, halogeno, hydroxyl, carboxyl, -OSO3H, -O-C1-6 Ak-R1a, C2-6 alkenyl substituted with C1-6 alkoxycarbonyl, or -CO-N(R1c)(R1d); R2 is hydrogen, halogeno, or -C1-6 Ak-CO-N(R1c)(R1d); and A is a group having a pyrimidine or 1-methylhydantoin ring as represented by the general formula (a), (b) or (c).

    摘要翻译： 通式（1）表示的萘衍生物，其具有优异的纤维蛋白溶解加速作用，可用作口服给药的抗血栓形成或血栓溶解药物，其中R1为氢，卤代，羟基，羧基，-OSO3H，-O-C1-6 Ak- R1a，被C1-6烷氧基羰基取代的C2-6烯基或-CO-N（R1c）（R1d）; R2是氢，卤素或-C1-6 Ak-CO-N（R1c）（R1d）; A为具有通式（a），（b）或（c）所示的嘧啶或1-甲基乙内酰脲环的基团。