QUINAZOLINE BASED EGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY
    4.
    发明申请
    QUINAZOLINE BASED EGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY 审中-公开
    喹唑啉类EGFR抑制剂含锌结合片的研究

    公开(公告)号:WO2008033748A3

    公开(公告)日:2008-12-24

    申请号:PCT/US2007077974

    申请日:2007-09-10

    CPC分类号: C07D239/94

    摘要: The present invention relates to quinazoline containing zinc-binding moiety based derivatives that have enhanced and unexpected properties as inhibitors of epidermal growth factor receptor tyrosine kinase (EGFR-TK) and their use in the treatment of EGFR-TK related diseases and disorders such as cancer.

    摘要翻译: 本发明涉及含有基于锌结合部分的衍生物的喹唑啉,其具有作为表皮生长因子受体酪氨酸激酶(EGFR-TK)抑制剂的增强和出乎意料的性质及其在治疗EGFR-TK相关疾病和病症例如癌症中的用途 。

    NEW SPIRO COMPOUNDS AND THEIR USE IN ORGANIC ELECTRONICS APPLICATIONS AND DEVICES
    6.
    发明申请
    NEW SPIRO COMPOUNDS AND THEIR USE IN ORGANIC ELECTRONICS APPLICATIONS AND DEVICES 审中-公开
    新型SPIRO化合物及其在有机电子应用和器件中的应用

    公开(公告)号:WO2014170839A3

    公开(公告)日:2014-10-23

    申请号:PCT/IB2014/060759

    申请日:2014-04-16

    摘要: The present invention relates to 9,9'-spirobifluorene compounds of general formula I wherein the variables have the meaning R 11 , R 12 , R 21 , R 22 ,R 31 , R 32 , R 41 and R 42 independently of each other aryl or hetaryl, S 1 , S 2 , S 3 and S 4 independently of each other π-conjugated, bivalent moieties, n 1 , n 2 , n 3 and n 4 independently of each other 0, 1, 2 or 3, with the proviso that n 1 + n 2 + n 3 + n 4 ≠ 0, in case n 1 ≥ 2, n 2 ≥ 2, n 3 ≥ 2 and/or n 4 ≥ 2 the moieties S 1 , S 2 , S 3 and S 4 are identical to or different from each other and in case n 1 + n 2 + n 3 + n 4 = 12 not all of the radicals R 11 , R 12 , R 21 , R 22 , R 31 , R 32 , R 41 and R 42 are identical, to the use of compounds of general formula I in organic electronics applications, especially in organic field effect transistors, in organic photodetectors and organic solar cells, specifically in dye-sensitized solar cells and bulk heterojunction solar cells, and to an organic field effect transistor, a dye-sensitized solar cell and a bulk heterojunction solar cell comprising compounds of general formula I.

    摘要翻译: 本发明涉及通式I的9,9'-螺二芴化合物,其中变量具有R 11,R 12,R 12, R 21,R 22,R 31,R 32,R 41和 R 42彼此独立地为芳基或杂芳基,S 1,S 2,S 3和S 4彼此独立地为0,1,2或3,条件是n 1 + n 2 + n 3 + 3 > + n <4>≠0,如果n <1> 2,n <2>≥2,n <3> ≥ 2和/或n 4≥2的部分S 1,S 2,S 3和S 4 彼此相同或不同,并且在n <1> + n <2> + n <3> + n 4 = 12时,不是所有的基团R 11,R 12,R 21, R 22,R 31,R 32,R 41和R 42是 与在有机电子应用中,特别是在有机场效应晶体管中,在有机光电探测器和有机太阳能电池中,特别是在染料敏化太阳能电池和本体异质结太阳能电池中以及有机场效应中使用通式I化合物 晶体管,染料敏化太阳能电池和包含通式I化合物的本体异质结太阳能电池。