摘要:
The present invention provides compounds, compositions and methods for treating and/or preventing a flavivirus infection by administering such compounds and compositions.
摘要:
This disclosure provides compounds and compositions for use as analgesics and for the treatment of various conditions, such as pain, headaches, allodynia, and fibromyalgia. The disclosure also provides compounds that are ligands, and in some embodiments, modulators (e.g., agonists), for the imidazoline receptor type 1.
摘要:
The present invention provides compounds, compositions and methods for treating and/or preventing a flavivirus infection by administering such compounds and compositions.
摘要:
The present invention relates to quinazoline containing zinc-binding moiety based derivatives that have enhanced and unexpected properties as inhibitors of epidermal growth factor receptor tyrosine kinase (EGFR-TK) and their use in the treatment of EGFR-TK related diseases and disorders such as cancer.
摘要:
The present invention relates to 9,9'-spirobifluorene compounds of general formula I wherein the variables have the meaning R 11 , R 12 , R 21 , R 22 ,R 31 , R 32 , R 41 and R 42 independently of each other aryl or hetaryl, S 1 , S 2 , S 3 and S 4 independently of each other π-conjugated, bivalent moieties, n 1 , n 2 , n 3 and n 4 independently of each other 0, 1, 2 or 3, with the proviso that n 1 + n 2 + n 3 + n 4 ≠ 0, in case n 1 ≥ 2, n 2 ≥ 2, n 3 ≥ 2 and/or n 4 ≥ 2 the moieties S 1 , S 2 , S 3 and S 4 are identical to or different from each other and in case n 1 + n 2 + n 3 + n 4 = 12 not all of the radicals R 11 , R 12 , R 21 , R 22 , R 31 , R 32 , R 41 and R 42 are identical, to the use of compounds of general formula I in organic electronics applications, especially in organic field effect transistors, in organic photodetectors and organic solar cells, specifically in dye-sensitized solar cells and bulk heterojunction solar cells, and to an organic field effect transistor, a dye-sensitized solar cell and a bulk heterojunction solar cell comprising compounds of general formula I.
摘要翻译:本发明涉及通式I的9,9'-螺二芴化合物,其中变量具有R 11,R 12,R 12, R 21,R 22,R 31,R 32,R 41和 R 42彼此独立地为芳基或杂芳基,S 1,S 2,S 3和S 4彼此独立地为0,1,2或3,条件是n 1 + n 2 + n 3 + 3 > + n <4>≠0,如果n <1> 2,n <2>≥2,n <3> sup>≥ 2和/或n 4≥2的部分S 1,S 2,S 3和S 4 sup>彼此相同或不同,并且在n <1> + n <2> + n <3> + n 4 = 12时,不是所有的基团R 11,R 12,R 21, R 22,R 31,R 32,R 41和R 42是 与在有机电子应用中,特别是在有机场效应晶体管中,在有机光电探测器和有机太阳能电池中,特别是在染料敏化太阳能电池和本体异质结太阳能电池中以及有机场效应中使用通式I化合物 晶体管,染料敏化太阳能电池和包含通式I化合物的本体异质结太阳能电池。 p>
摘要:
The invention relates to N-oxides of tamoxifen analogs having activity for treating hyperproliferative disorders. Pharmaceutical compositions comprising therapeutically effective amount of an N-oxide of an estrogen receptor modulator, or a pharmaceutically acceptable salt or prodrug thereof, are disclosed. Further, the invention relates to methods of using the compounds, alone or in combination with one or more other active agents or treatments, to treat hyperproliferative disorders.
摘要:
New ligands having a backbone comprised of NCCX can be combined with a metal or metal precursor compound or formed into a metal-ligand complex to catalyze a number of different chemical transformations, including polymerization.