利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

5 条记录 (耗时 0.011 秒)

    ALPHA-FLUORO ALKYNOIC ACIDS WITH ANTICONVULSANT ACTIVITY
    1.
    发明申请
    ALPHA-FLUORO ALKYNOIC ACIDS WITH ANTICONVULSANT ACTIVITY 审中-公开
    具有抗病毒活性的ALPHA-FLUORO ALKYNOIC酸

    公开(公告)号：WO99067195A1

    公开(公告)日：1999-12-29

    申请号：PCT/US1999/013838

    申请日：1999-06-22

    IPC分类号： C07C57/52 ,  C07C57/56 ,  C07C67/307 ,  C07C67/343 ,  A61K31/16 ,  A61K31/19 ,  A61K31/215 ,  C07C69/65 ,  C07C233/09 ,  C07C233/10 ,  C07C233/20 ,  C07C233/21 ,  C07C233/38 ,  C07C233/39

    CPC分类号： C07C67/307 ,  C07C57/52 ,  C07C57/56 ,  C07C67/343 ,  C07C69/65 ,  C07C69/606

    摘要： Alpha-fluorinated alkynoic acids of structure (I) wherein R is C3 to C10 alkyl, C3 to C6 cycloalkyl, or cyclopropylmethyl, and R is C1 to C3 alkyl or cyclopropyl, and the pharmaceutically acceptable salts, esters, and amides thereof; and pharmaceutical compositions containing these compounds are provided, which are useful for the treatment and prevention of seizures such as are associated with epilepsy. The compounds of the invention exhibit reduced side effects, relative to valproic acid, with regard to sedation and teratogenic potential.

    摘要翻译： 其中R 1为C 3至C 10烷基，C 3至C 6环烷基或环丙基甲基的结构（I）的α-氟化炔丙基，R 2为C 1至C 3烷基或环丙基，其药学上可接受的盐，酯， 及其酰胺; 并提供含有这些化合物的药物组合物，其可用于治疗和预防与癫痫相关的癫痫发作。 相对于丙戊酸，本发明的化合物在镇静和致畸潜能方面表现出减少的副作用。

    AMINE ADDUCTS, DERIVATIVES THEREOF, METHODS FOR MAKING SUCH ADDUCTS AND DERIVATIVES, AND METHODS FOR USING SUCH ADDUCTS AND DERIVATIVES
    2.
    发明申请
    AMINE ADDUCTS, DERIVATIVES THEREOF, METHODS FOR MAKING SUCH ADDUCTS AND DERIVATIVES, AND METHODS FOR USING SUCH ADDUCTS AND DERIVATIVES 审中-公开
    胺助剂，其衍生物，制备此类添加剂和衍生物的方法，以及使用此类添加剂和衍生物的方法

    公开(公告)号：WO2013093626A3

    公开(公告)日：2013-11-21

    申请号：PCT/IB2012002993

    申请日：2012-12-21

    申请人： RHODIA OPERATIONS

    发明人： PAKENHAM DEREK ,  MORVAN MIKEL ,  DEGRE GUILLAUME

    IPC分类号： C07C233/39 ,  C07C309/14 ,  C09K8/584 ,  C11D1/94 ,  E21B43/20

    CPC分类号： C09K8/584 ,  C07C227/02 ,  C07C231/14 ,  C07C233/38 ,  C07C233/39 ,  C07C303/20 ,  C07C309/14 ,  C11D1/62 ,  C11D1/90 ,  C11D1/92 ,  C11D1/94 ,  E21B43/16 ,  E21B43/26 ,  Y10T137/0318

    摘要： An amine adduct is made by (1 ) forming an addition intermediate by heating a mixture comprising at least one diene and at least one unsaturated fatty acyl compound, and reacting the addition intermediate with a diamine to form the amine adduct, or by (2) reacting at least one unsaturated fatty acyl compound with at least one diamine to form an amine intermediate, and heating a mixture of the amidoamine intermediate and at least one diene to form the amine adduct, or by (3) reacting at least one unsaturated fatty tertiary amine compound with at least at least one diene to form the amine adduct. A surfactant composition is derived from the amine adduct and is particularly useful in a method for enhancing the recovery of oil from a reservoir having a production wellbore, comprising introducing an aqueous flooding fluid into the reservoir at one or more locations different from the location of the production wellbore, said fluid comprising the surfactant composition and recovering the oil through the production wellbore.

    摘要翻译： 通过（1）通过加热包含至少一种二烯和至少一种不饱和脂肪酰基化合物的混合物形成加成中间体，并使加成中间体与二胺反应形成胺加合物，或通过（2） 使至少一种不饱和脂肪酰基化合物与至少一种二胺反应形成胺中间体，并加热酰胺胺中间体和至少一种二烯的混合物以形成胺加合物，或通过（3）使至少一种不饱和脂肪三 胺化合物与至少一种二烯形成胺加合物。 表面活性剂组合物衍生自胺加合物，并且特别可用于增强从具有生产井眼的储层中回收油的方法，包括将水性驱油流体引导到不同于 所述流体包含表面活性剂组合物并通过生产井眼回收油。