公开(公告)号：US20070059437A1

公开(公告)日：2007-03-15

申请号：US11441265

申请日：2006-05-25

申请人： William Murphy ,  Martin Peters ,  David Mooney ,  David Kohn

发明人： William Murphy ,  Martin Peters ,  David Mooney ,  David Kohn

IPC分类号： B05D3/00

CPC分类号： A61L27/58 ,  A61L27/00 ,  A61L27/18 ,  A61L27/306 ,  A61L27/44 ,  A61L27/50 ,  A61L27/56 ,  A61L2400/18 ,  A61L2430/02 ,  C08L67/04

摘要： Disclosed are advantageous methods for patterning and/or mineralizing biomaterial surfaces. The techniques described are particularly useful for generating three-dimensional or contoured bioimplant materials with patterned surfaces or patterned, mineralized surfaces. Also provided are various methods of using the mineralized and/or patterned biomaterials in tissue engineering, such as bone tissue engineering, providing more control over ongoing biological processes, such as mineralization, growth factor release, cellular attachment and tissue growth.

摘要翻译： 公开了用于图案化和/或矿化生物材料表面的有利方法。 所描述的技术对于生成具有图案化表面或图案化的矿化表面的三维或轮廓生物植入物材料特别有用。 还提供了在组织工程中使用矿化和/或图案化生物材料的各种方法，例如骨组织工程，提供对正在进行的生物过程例如矿化，生长因子释放，细胞附着和组织生长的更多控制。

公开(公告)号：US20050002982A1

公开(公告)日：2005-01-06

申请号：US10726072

申请日：2003-12-01

申请人： David Mooney ,  Charles Vacanti ,  Craig Halberstadt ,  Andrea Ferguson ,  Jennifer Marler ,  Byung-Soo Kim

发明人： David Mooney ,  Charles Vacanti ,  Craig Halberstadt ,  Andrea Ferguson ,  Jennifer Marler ,  Byung-Soo Kim

IPC分类号： A61K35/12 ,  A61K48/00 ,  A61L27/38 ,  C12N5/071

CPC分类号： A61L27/3886 ,  A61K35/12 ,  A61K48/00 ,  A61L27/3817 ,  A61L27/3821 ,  A61L27/3826 ,  A61L27/383 ,  A61L27/3847 ,  A61L27/3852 ,  A61L27/3895 ,  C12N5/0697 ,  C12N2502/1317 ,  C12N2502/28 ,  C12N2533/40

摘要： The present invention comprises an implantable device that provides artificial tissues for repair, augmentation and reconstructive surgery which have mechanical properties comparable to the natural tissues that they supplement or replace. Such devices can be produced by a tissue engineering method comprising seeding a polymer matrix with a first cell type and a second cell type and culturing the seeded matrix under conditions suitable for cell growth or maintenance, whereby a tissue comprising a mixed cell population containing both the first and second cell types is produced. The tissue produced by this method contains a mixed population in which the two cell types are intimately associated without apparent stratification and has mechanical properties which are intermediate between similarly produced tissues containing either one of the two cell types. This invention is particularly useful in forming implantable structural members.

摘要翻译： 本发明包括可植入装置，其提供用于修复，增加和重建手术的人造组织，其具有与其补充或替代的天然组织相当的机械性能。 这样的装置可以通过组织工程方法来生产，包括将具有第一种细胞类型和第二种细胞类型的聚合物基质接种，并在适于细胞生长或维持的条件下培养接种的基质，由此将包含混合细胞群的组织 产生第一和第二细胞类型。 通过该方法产生的组织包含混合群体，其中两种细胞类型密切相关而没有明显的分层，并且具有在含有两种细胞类型之一的类似产生的组织之间中间的机械性质。 本发明特别可用于形成可植入结构构件。

公开(公告)号：US06639972B1

公开(公告)日：2003-10-28

申请号：US09300025

申请日：1999-04-27

申请人： Joseph M. Cannon ,  Donald Alfred Fleck ,  James A. Johnason ,  Philip David Mooney

发明人： Joseph M. Cannon ,  Donald Alfred Fleck ,  James A. Johnason ,  Philip David Mooney

IPC分类号： H04M1100

CPC分类号： H04L43/00 ,  H04M3/42042 ,  H04M3/533 ,  H04M3/53366 ,  H04M2203/4563

摘要： A method for screening of an active voice mail message enables real time monitoring by a subscriber to the voice mail system of incoming calls. Once the identity of the subscriber is established, the subscriber is presented with the option of screening an incoming message. A subscriber desiring to screen the message responds by activating a predetermined key or sequence of keys to enter a listen-only mode for monitoring of the incoming message. The subscriber may then interrupt the message and take the call, continue listening to the incoming message, or terminate listen-only mode and simply permit the message to be stored for later retrieval.

摘要翻译： 用于筛选活动语音邮件消息的方法使得用户能够对来电的语音邮件系统进行实时监控。 一旦建立了订户的身份，就向用户呈现筛选进入消息的选项。 希望屏蔽消息的用户通过激活预定的密钥或序列来进行响应，以进入用于监听传入消息的仅监听模式。 用户然后可以中断消息并接听电话，继续监听传入消息，或者终止只听模式，并且简单地允许消息被存储以供以后检索。

公开(公告)号：US06511650B1

公开(公告)日：2003-01-28

申请号：US09958376

申请日：2002-04-18

申请人： Petra Eiselt ,  Craig Halberstadt ,  David Mooney ,  Julia Yeh ,  Rachel Latvala ,  Jon A. Rowley

发明人： Petra Eiselt ,  Craig Halberstadt ,  David Mooney ,  Julia Yeh ,  Rachel Latvala ,  Jon A. Rowley

IPC分类号： A61L1542

CPC分类号： C08J9/30 ,  A61L27/20 ,  A61L27/52 ,  A61L27/56 ,  A61L31/042 ,  A61L31/145 ,  A61L31/146 ,  C08J9/08 ,  C08J2205/022 ,  C08J2305/04 ,  C12N5/0068 ,  C12N2533/74 ,  C08L5/04

摘要： This invention is directed to a new approach to form porous hydrogel materials by first creating gas pockets in the gel and then removing this gas. The removal of the gas creates a porous material, and the initial incorporation of sufficient gas allows one to create a material with an open, interconnected pore structure. Advantageous features of the resulting materials, in addition to their interconnected pore structure, may include that the pore structure is maintained over extended time periods and that the gels maintain a high mechanical integrity that allows seeding with cells and implantation without destruction or compression of the material.

摘要翻译： 本发明涉及通过首先在凝胶中产生气体袋然后除去该气体来形成多孔水凝胶材料的新方法。 气体的去除产生多孔材料，并且初始引入足够的气体允许产生具有开放的互连孔结构的材料。 所得材料的有利特征除了其相互连接的孔结构之外，可以包括孔结构在延长的时间段内保持，并且凝胶保持高机械完整性，允许使用细胞进行接种并且不会破坏或压缩材料 。

公开(公告)号：US06269257B1

公开(公告)日：2001-07-31

申请号：US09234737

申请日：1999-01-21

申请人： Joseph M. Cannon ,  James A. Johanson ,  Philip David Mooney

发明人： Joseph M. Cannon ,  James A. Johanson ,  Philip David Mooney

IPC分类号： H04M100

CPC分类号： G08B21/0247 ,  G08B21/24 ,  H04M1/72502 ,  H04M1/72519

摘要： In one embodiment, a cordless telephone according to the invention includes a base unit, including a paging mechanism, and a handset, including an alerting mechanism responsive to the paging mechanism. At least one of the base unit and the handset includes a page adjusting mechanism to affect an alerting signal output from the alerting mechanism based on a condition. Thus, the paging signal is adaptive to increase the opportunity for a user to determine the location of a misplaced handset. In another embodiment, a cordless telephone is equipped so that the base unit can provide an indication related to a distance between the base unit and the handset. In yet another embodiment, a cordless telephone is equipped so that the paging mechanism is adjusted based on user control. In a further embodiment according to the invention, a method is provided for affecting an alerting signal output by an alerting mechanism of a cordless telephone handset. The method includes the steps of sensing a condition, and affecting the alerting signal based on the sensed condition.

公开(公告)号：US20070023728A1

公开(公告)日：2007-02-01

申请号：US11527277

申请日：2006-09-26

申请人： Sylvester Ledo ,  David Mooney

发明人： Sylvester Ledo ,  David Mooney

IPC分类号： F16K3/00

CPC分类号： F16K3/0272 ,  F16K27/003 ,  Y10T137/87885

摘要： A valve manifold that is adapted to be positioned between a main flow line and a measuring instrument, including a body; a pair of fluid flow passages in said body, each having one port for coupling with the main flow line and an opposite end port for coupling with the measuring instrument; a pair of valve members for controlling the fluid flow through the respective pair of fluid flow passages; and a pair of handles for respectively controlling said pair of valve members. Each of the valve members includes a control end coupling with a respective handle to control the position of the valve member and a valving end adapted for positioning in a valve passage that extends transverse to the fluid flow passage. Each valve member further has a resilient seal member that is supported by either the body or valve member and that, in a closed position, provides a seal about the fluid flow passage between the valve member and body so as to inhibit fluid flow through the fluid flow passage, and that, in at least a partially open position, enables fluid flow through the fluid flow passage.

摘要翻译： 一种适于定位在主流线和包括主体的测量仪器之间的阀歧管; 所述主体中的一对流体流动通道各自具有用于与所述主流动管线连接的一个端口和用于与所述测量仪器联接的相对的端部端口; 一对阀构件，用于控制通过相应的一对流体流动通道的流体流动; 以及用于分别控制所述一对阀构件的一对把手。 每个阀构件包括与相应手柄联接以控制阀构件的位置的控制端和适于定位在横向于流体流动通道延伸的阀通道中的阀端。 每个阀构件还具有弹性密封构件，其由主体或阀构件支撑，并且在关闭位置中，围绕阀构件和主体之间的流体流动通道提供密封，以便阻止流体流过流体 流动通道，并且在至少部分打开位置使得流体流过流体流动通道。

公开(公告)号：US20050252563A1

公开(公告)日：2005-11-17

申请号：US11119841

申请日：2005-05-02

申请人： Sylvester Ledo ,  David Mooney

发明人： Sylvester Ledo ,  David Mooney

IPC分类号： F16K3/02 ,  F16K27/00

CPC分类号： F16K3/0272 ,  F16K27/003 ,  Y10T137/87885

摘要： A valve manifold that is adapted to be positioned between a main flow line and a measuring instrument, including a body; a pair of fluid flow passages in said body, each having one port for coupling with the main flow line and an opposite end port for coupling with the measuring instrument; a pair of valve members for controlling the fluid flow through the respective pair of fluid flow passages; and a pair of handles for respectively controlling said pair of valve members. Each of the valve members includes a control end coupling with a respective handle to control the position of the valve member and a valving end adapted for positioning in a valve passage that extends transverse to the fluid flow passage. Each valve member further has a resilient seal member that is supported by either the body or valve member and that, in a closed position, provides a seal about the fluid flow passage between the valve member and body so as to inhibit fluid flow through the fluid flow passage, and that, in at least a partially open position, enables fluid flow through the fluid flow passage.

摘要翻译： 一种适于定位在主流线和包括主体的测量仪器之间的阀歧管; 所述主体中的一对流体流动通道各自具有用于与所述主流动管线连接的一个端口和用于与所述测量仪器联接的相对的端部端口; 一对阀构件，用于控制通过相应的一对流体流动通道的流体流动; 以及用于分别控制所述一对阀构件的一对把手。 每个阀构件包括与相应手柄联接以控制阀构件的位置的控制端和适于定位在横向于流体流动通道延伸的阀通道中的阀端。 每个阀构件还具有弹性密封构件，其由主体或阀构件支撑，并且在关闭位置中，围绕阀构件和主体之间的流体流动通道提供密封，以便阻止流体流过流体 流动通道，并且在至少部分打开位置使得流体流过流体流动通道。

公开(公告)号：US06233322B1

公开(公告)日：2001-05-15

申请号：US09220586

申请日：1998-12-28

申请人： Joseph M. Cannon ,  Donald Alfred Fleck ,  Philip David Mooney

发明人： Joseph M. Cannon ,  Donald Alfred Fleck ,  Philip David Mooney

IPC分类号： H04M1100

CPC分类号： H04M3/53366 ,  H04M3/436 ,  H04M2201/18

摘要： Unique, electronic mailboxes may be configured to allow multiple users to use a single mailbox for storing messages and for screening messages using information related to the messages, such as the name and telephone number of the originator of a message. The unique mailboxes may be configured using systems and methods which make use of user-defined filters which may be applied to each mailbox. Each mailbox may be additionally protected by a password for changing the user defined filters and for retrieving messages.

摘要翻译： 唯一的电子邮箱可以被配置为允许多个用户使用单个邮箱来存储消息，并且使用与消息相关的信息（例如消息的发起者的姓名和电话号码）来筛选消息。 可以使用可以应用于每个邮箱的用户定义的过滤器的系统和方法来配置唯一邮箱。 每个邮箱可以额外受到用于改变用户定义的过滤器和检索消息的密码的保护。

公开(公告)号：US07361158B1

公开(公告)日：2008-04-22

申请号：US09477572

申请日：2000-01-04

申请人： Paul David Mooney, Jr.

发明人： Paul David Mooney, Jr.

IPC分类号： A61M5/32

CPC分类号： A61M25/0043 ,  A61M25/06

摘要： A catheter including a body for insertion into a blood vessel of a medical patient. The body including an interface thereon which is the portion of the body that is inserted into and in contact with the skin or blood vessel of the patient. The interface includes texture on its exterior surface such that when the catheter body is inserted into the blood vessel, the texture secures the catheter body from migration at the point of entry of the catheter body into the patient. The texture is obtained by scoring or molding an irregular surface along the length of the interface. In the event that the catheter is configured for use with an introducer or cannula, portions of the introducer or cannula may also be textured in accordance with the invention.

摘要翻译： 一种导管，其包括用于插入到医疗患者的血管中的主体。 身体包括其上插入到患者的皮肤或血管中并与其接触的身体部分的界面。 该界面包括其外表面上的纹理，使得当导管主体插入血管时，纹理将导管主体在导管主体进入患者体内的过程中保持不动。 通过沿着界面的长度刻痕或模制不规则表面来获得纹理。 在导管配置成与导引器或插管一起使用的情况下，导引器或套管的部分也可以根据本发明进行纹理化。

公开(公告)号：US20070174325A1

公开(公告)日：2007-07-26

申请号：US11338212

申请日：2006-01-24

申请人： David Mooney ,  Kelly Rodger ,  Michael Roecken

发明人： David Mooney ,  Kelly Rodger ,  Michael Roecken

IPC分类号： G06F7/00

CPC分类号： G06F11/1448 ,  G06F11/1469 ,  G06F11/1471

摘要： Building a database from stored backup data images. In one aspect, an identification of a target image is received, the target image including a copy of a logical storage unit of data from a previous database and description information that describes the previous database. The target image holds a copy of a subset of the data of the previous database. A received list has at least one desired logical storage unit of data from the previous database to be included in a built database. The desired logical storage unit is restored from at least one stored data image to the built database using the description information in the target image. Other aspects include the target image being a database image, and the desired logical storage units of data being a subset of database data.

摘要翻译： 从存储的备份数据映像构建数据库。 一方面，接收目标图像的识别，目标图像包括来自先前数据库的数据的逻辑存储单元的副本和描述先前数据库的描述信息。 目标图像保存以前数据库的数据子集的副本。 接收到的列表具有至少一个期望的来自先前数据库的数据的逻辑存储单元，以被包括在内置的数据库中。 使用目标图像中的描述信息，将期望的逻辑存储单元从至少一个存储的数据图像恢复到内置的数据库。 其他方面包括作为数据库图像的目标图像，并且期望的逻辑存储单元的数据是数据库数据的子集。