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    Malodour standards and inhibitors
    1.
    发明授权
    Malodour standards and inhibitors 有权
    Malodour标准和抑制剂

    公开(公告)号：US09249448B2

    公开(公告)日：2016-02-02

    申请号：US13994289

    申请日：2011-12-19

    申请人： Markus Pompejus

    发明人： Markus Pompejus

    IPC分类号： C12Q1/25 ,  C12N9/84 ,  A61K8/36 ,  A61Q15/00

    CPC分类号： C12Q1/25 ,  A61K8/36 ,  A61K8/64 ,  A61Q15/00 ,  C12N9/84

    摘要： The invention pertains to the field of reaction systems generating malodor, particularly from constituents of human sweat. Specifically, the invention pertains to proteins for generating malodors, substrates for generating such malodor, inhibitors of such malodor generation and test and screening systems for measuring their malodor inhibition efficacy and finding substances previously not known to inhibit malodor generation. Thus, the invention also pertains to the field of deodorants.

    摘要翻译： 本发明涉及产生恶臭的反应系统领域，特别是人汗的成分。 具体地，本发明涉及用于产生恶臭的蛋白质，用于产生这种恶臭的底物，这种恶臭产生的抑制剂以及测量和筛选系统，用于测量其恶臭抑制功效并发现先前不知道抑制恶臭产生的物质。 因此，本发明也涉及除臭剂领域。

    Oral Health Improving Compositions
    2.
    发明申请
    Oral Health Improving Compositions 审中-公开
    口腔健康改善组合

    公开(公告)号：US20130344010A1

    公开(公告)日：2013-12-26

    申请号：US13981194

    申请日：2012-01-12

    申请人： Markus Pompejus

    发明人： Markus Pompejus

    IPC分类号： A61K8/99 ,  A61Q11/00

    CPC分类号： A61K8/99 ,  A23K10/16 ,  A23K10/18 ,  A23K50/42 ,  A23L33/135 ,  A61K35/74 ,  A61P1/02 ,  A61Q11/00

    摘要： The present invention is concerned with microorganisms or fragments thereof as sensorically neutral oral care agents, particularly for prevention of dental calculus, as anti-caries agents and/or anti-oral malodor agents. The invention is furthermore concerned with compositions comprising microorganisms or fragments thereof for reducing mutans Streptococci. Such compositions can be used in oral care compositions, e.g. for caries prophylaxis, or for prophylaxis of dental calculus or oral malodor. They may also or instead be used for prevention or treatment of oral malodor. As the microorganisms and fragments thereof according to the present invention have a very low, unobtrusive smell and taste, they are particularly suited as sensorically neutral agents for preventment of dental calculus, caries, oral biofilm formation and/or for prevention or treatment of oral malodor. The microorganisms and fragments thereof, and also compositions comprising such microorganisms and fragments, can thus advantageously be used in food and feed compositions, particularly in pet foods. Furthermore, the invention is concerned with methods of preparing such microorganisms, fragments, compositions, foods and feeds.

    摘要翻译： 本发明涉及作为感觉中性口腔护理剂的微生物或其片段，特别是用于预防牙结石，作为抗龋剂和/或抗口腔恶臭剂。 本发明还涉及包含用于降低变形链球菌的微生物或其片段的组合物。 这样的组合物可以用于口腔护理组合物，例如 用于龋齿预防，或预防牙结石或口腔恶臭。 他们也可以或替代地用于预防或治疗口臭。 由于根据本发明的微生物及其碎片具有非常低的，不显眼的气味和味道，所以它们特别适用于用于预防牙结石，龋齿，口腔生物膜形成和/或预防或治疗口腔恶臭的感觉中性剂 。 微生物及其片段以及包含这些微生物和碎片的组合物因此可有利地用于食品和饲料组合物中，特别是在宠物食品中。 此外，本发明涉及制备这种微生物，碎片，组合物，食品和饲料的方法。

    Malodour Standards And Inhibitors
    3.
    发明申请
    Malodour Standards And Inhibitors 有权
    Malodour标准和抑制剂

    公开(公告)号：US20130315851A1

    公开(公告)日：2013-11-28

    申请号：US13994289

    申请日：2011-12-19

    申请人： Markus Pompejus

    发明人： Markus Pompejus

    IPC分类号： C12Q1/25 ,  A61K8/36 ,  A61Q15/00

    CPC分类号： C12Q1/25 ,  A61K8/36 ,  A61K8/64 ,  A61Q15/00 ,  C12N9/84

    摘要： The invention pertains to the field of reaction systems generating malodour, particularly from constituents of human sweat. Specifically, the invention pertains to proteins for generating malodours, substrates for generating such malodour, inhibitors of such malodour generation and test and screening systems for measuring their malodour inhibition efficacy and finding substances previously not known to inhibit malodour generation. Thus, the invention also pertains to the field of deodorants.

    摘要翻译： 本发明涉及产生恶臭的反应系统领域，特别是人汗的成分。 具体地，本发明涉及用于产生恶臭的蛋白质，用于产生这种恶臭的底物，这种恶臭产生的抑制剂以及用于测量其恶臭抑制功效的测试和筛选系统，并且发现先前不知道抑制恶臭产生的物质。 因此，本发明也涉及除臭剂领域。

    Method for producing methionine using a microorganism with reduced expression activity of a negative regulator of methionine biosynthesis
    4.
    发明授权
    Method for producing methionine using a microorganism with reduced expression activity of a negative regulator of methionine biosynthesis 有权
    使用具有降低甲硫氨酸生物合成负调节子的表达活性的微生物生产甲硫氨酸的方法

    公开(公告)号：US08389251B2

    公开(公告)日：2013-03-05

    申请号：US13018119

    申请日：2011-01-31

    申请人： Markus Pompejus ,  Burkhard Kröger ,  Hartwig Schröder ,  Oskar Zelder ,  Gregor Haberhauer ,  Stefan Haefner ,  Corrinna Klopprogge

    发明人： Markus Pompejus ,  Burkhard Kröger ,  Hartwig Schröder ,  Oskar Zelder ,  Gregor Haberhauer ,  Stefan Haefner ,  Corrinna Klopprogge

    IPC分类号： C12P13/12 ,  C12N15/74

    CPC分类号： C07K14/34

    摘要： Isolated nucleic acid molecules, designated MR nucleic acid molecules, which encode novel MR proteins from Corynebacterium glutamicum are described which are involved in biosynthesis of a fine chemical, e.g., methionine biosynthesis. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MR nucleic acid molecules, and host cells into which the expression vectors have been introduced. The invention still further provides methods of producing methionine from microorganisms, e.g., C. glutamicum, which involve culturing recombinant microorganisms which overexpress or underexpress at least one MR molecule of the invention under conditions such that methionine is produced. Also featured are methods of producing a fine chemical, e.g., methionine, which involve culturing recombinant microorganisms having selected MR genes deleted or mutated under conditions such that the fine chemical, e.g., methionine, is produced.

    摘要翻译： 描述了编码来自谷氨酸棒杆菌的新型MR蛋白质的分离的核酸分子，称为MR核酸分子，其涉及精细化学品的生物合成，例如甲硫氨酸生物合成。 本发明还提供反义核酸分子，含有MR核酸分子的重组表达载体和已经引入表达载体的宿主细胞。 本发明还提供了从微生物例如谷氨酸棒杆菌制备甲硫氨酸的方法，其涉及在产生甲硫氨酸的条件下培养过表达或低表达本发明的至少一种MR分子的重组微生物。 还特征在于生产精细化学品的方法，例如甲硫氨酸，其涉及在产生精细化学物质例如甲硫氨酸的条件下培养具有选择的MR基因缺失或突变的重组微生物。