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公开(公告)号：US07991461B2
公开(公告)日：2011-08-02
申请号：US11315225
申请日：2005-12-23
申请人： J. Christopher Flaherty , Mijail D. Serruya , Daniel S. Morris , Abraham H. Caplan , Maryam Saleh , John P. Donoghue
发明人： J. Christopher Flaherty , Mijail D. Serruya , Daniel S. Morris , Abraham H. Caplan , Maryam Saleh , John P. Donoghue
IPC分类号： A61B5/04
CPC分类号： A61B5/04001 , A61B5/0482 , G06F3/015
摘要： Various embodiments of a biological interface system and related methods are disclosed. The system may comprise a sensor comprising a plurality of electrodes for detecting multicellular signals emanating from one or more living cells of a patient and a processing unit configured to receive the multicellular signals from the sensor and process the multicellular signals to produce a processed signal. The processing unit may be configured to transmit the processed signal to a controlled device that is configured to receive the processed signal. The system is configured to perform an integrated patient training routine to generate one or more system configuration parameters that are used by the processing unit to produce the processed signal.
摘要翻译： 公开了生物界面系统和相关方法的各种实施例。 该系统可以包括传感器，其包括用于检测从患者的一个或多个活细胞发出的多细胞信号的多个电极和被配置为从传感器接收多细胞信号并处理多细胞信号以产生经处理的信号的处理单元。 处理单元可以被配置为将经处理的信号发送到被配置为接收经处理的信号的受控设备。 该系统被配置为执行综合的患者训练程序，以产生一个或多个系统配置参数，该系统配置参数由处理单元用于产生经处理的信号。
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公开(公告)号：US20100063411A1
公开(公告)日：2010-03-11
申请号：US12285886
申请日：2008-10-15
申请人： John P. Donoghue , J. Christopher Flaherty , Mijail D. Serruya , Abraham H. Caplan , Maryam Saleh , Kirk F. Korver , Almut Branner
发明人： John P. Donoghue , J. Christopher Flaherty , Mijail D. Serruya , Abraham H. Caplan , Maryam Saleh , Kirk F. Korver , Almut Branner
IPC分类号： A61B5/0484
CPC分类号： G06F3/015 , A61B5/0006 , A61B5/04001 , G06F19/00 , G16H40/40
摘要： A system and method for a neural interface system with integral calibration elements may include a sensor including a plurality of electrodes to detect multicellular signals, an interface to process the signals from the sensor into a suitable control signal for a controllable device, such as a computer or prosthetic limb, and an integrated calibration routine to efficiently create calibration output parameters used to generate the control signal. A graphical user interface may be used to make various portions of the calibration and signal processing configuration more efficient and effective.
摘要翻译： 具有整体校准元件的神经接口系统的系统和方法可以包括传感器，其包括用于检测多细胞信号的多个电极，用于处理来自传感器的信号到用于可控设备（例如计算机）的合适控制信号的接口 或假肢，以及集成校准例程，以有效地产生用于产生控制信号的校准输出参数。 可以使用图形用户界面来使得校准和信号处理配置的各个部分更有效和有效。
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公开(公告)号：US08386050B2
公开(公告)日：2013-02-26
申请号：US12285886
申请日：2008-10-15
申请人： John P. Donoghue , J. Christopher Flaherty , Mijail D. Serruya , Abraham H. Caplan , Maryam Saleh , Kirk F. Korver , Almut Branner
发明人： John P. Donoghue , J. Christopher Flaherty , Mijail D. Serruya , Abraham H. Caplan , Maryam Saleh , Kirk F. Korver , Almut Branner
IPC分类号： A61N1/3605 , A61B5/04001 , A61B5/0422
CPC分类号： G06F3/015 , A61B5/0006 , A61B5/04001 , G06F19/00 , G16H40/40
摘要： A system and method for a neural interface system with integral calibration elements may include a sensor including a plurality of electrodes to detect multicellular signals, an interface to process the signals from the sensor into a suitable control signal for a controllable device, such as a computer or prosthetic limb, and an integrated calibration routine to efficiently create calibration output parameters used to generate the control signal. A graphical user interface may be used to make various portions of the calibration and signal processing configuration more efficient and effective.
摘要翻译： 具有整体校准元件的神经接口系统的系统和方法可以包括传感器，其包括用于检测多细胞信号的多个电极，用于处理来自传感器的信号到用于可控设备（例如计算机）的合适控制信号的接口 或假肢，以及集成校准例程，以有效地产生用于产生控制信号的校准输出参数。 可以使用图形用户界面来使得校准和信号处理配置的各个部分更有效和有效。
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公开(公告)号：US07751877B2
公开(公告)日：2010-07-06
申请号：US10992111
申请日：2004-11-19
申请人： J. Christopher Flaherty , L. Renée Capachione , Daniel S. Morris , Abraham H. Caplan , Maryam Saleh , K. Shane Guillory
发明人： J. Christopher Flaherty , L. Renée Capachione , Daniel S. Morris , Abraham H. Caplan , Maryam Saleh , K. Shane Guillory
IPC分类号： A61B5/00
CPC分类号： A61B5/0031 , A61B5/04001 , A61B2560/0223 , A61B2560/045 , A61B2562/08
摘要： A system and method for a neural interface system with a unique identification code includes a sensor including a plurality of electrodes to detect multicellular signals, an processing unit to process the signals from the sensor into a suitable control signal for a controllable device such as a computer or prosthetic limb. The unique identification code is embedded in one or more discrete components of the system. Internal and external system checks for compatibility and methods of ensuring safe and effective performance of a system with detachable components are also disclosed.
摘要翻译： 一种用于具有唯一识别码的神经接口系统的系统和方法包括：传感器，包括用于检测多细胞信号的多个电极;处理单元，用于将来自传感器的信号处理成用于诸如计算机之类的可控设备的合适的控制信号 或假肢。 唯一的识别码嵌入在系统的一个或多个分立组件中。 还公开了内部和外部系统检查兼容性以及确保具有可拆卸部件的系统的安全和有效性能的方法。
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公开(公告)号：US07647097B2
公开(公告)日：2010-01-12
申请号：US11014907
申请日：2004-12-20
IPC分类号： A61B5/04
CPC分类号： A61N1/0529 , A61B5/04001 , A61B5/4041 , A61B5/6864 , A61M39/0247 , A61M2039/025 , A61M2039/0267 , A61M2039/0288 , A61M2205/3569 , A61M2205/3592 , A61N1/0531 , A61N1/0539 , A61N1/375 , A61N1/3787
摘要： Devices, systems and methods are disclosed for a neural access device that includes an implant which transcutaneously exits the skin of a patient and provides transport of signals between a sensor implanted in a patient and an external device. The transcutaneous implant has integrated features to provide reduced risk of injury due to mechanical forces as well as electrostatic discharge energy applied to the external portion of the device. Transcutaneous devices which provide wireless communication between a sensor and an external device are also disclosed.
摘要翻译： 公开了用于神经访问装置的装置，系统和方法，其包括经皮离开患者皮肤的植入物，并且在植入患者体内的传感器和外部装置之间提供信号传输。 经皮植入物具有集成的特征，以减少由于机械力的损伤风险以及施加到装置的外部部分的静电放电能量。 还公开了在传感器和外部设备之间提供无线通信的经皮装置。
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公开(公告)号：US07901368B2
公开(公告)日：2011-03-08
申请号：US11319237
申请日：2005-12-29
CPC分类号： A61N1/08 , A61H1/0255 , A61H1/0277 , A61H3/00 , A61H3/008 , A61H3/04 , A61H2201/1635 , A61H2201/1638 , A61H2201/1642 , A61H2201/1676 , A61H2201/5058 , A61H2201/5061 , A61H2201/5071 , A61H2201/5082 , A61H2203/03 , A61H2230/085 , A61H2230/10 , A61H2230/605 , A61N1/36003
摘要： Various embodiments of an ambulation system and a movement assist system are disclosed. For example, an ambulation system for a patient may comprise a biological interface apparatus and an ambulation assist apparatus. The biological interface apparatus may comprise a sensor having a plurality of electrodes for detecting multicellular signals, a processing unit configured to receive the multicellular signals from the sensor, process the multicellular signals to produce a processed signal, and transmit the processed signal to a controlled device. The ambulation assist apparatus may comprise a rigid structure configured to provide support between a portion of the patient's body and a surface. Data may be transferred from the ambulation assist apparatus to the biological interface apparatus.
摘要翻译： 公开了一种行走系统和运动辅助系统的各种实施例。 例如，患者的行走系统可以包括生物界面装置和行走辅助装置。 生物界面装置可以包括具有用于检测多细胞信号的多个电极的传感器，处理单元，被配置为从传感器接收多细胞信号，处理多细胞信号以产生经处理的信号，并将经处理的信号发送到受控装置 。 移动辅助装置可以包括构造成在患者身体的一部分和表面之间提供支撑的刚性结构。 数据可以从行走辅助装置传送到生物界面装置。
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公开(公告)号：US08812096B2
公开(公告)日：2014-08-19
申请号：US11320710
申请日：2005-12-30
IPC分类号： A61B5/04 , G06F3/01 , A61F2/50 , A61F2/68 , G09B23/28 , G06N3/06 , G09B19/00 , A61F2/76 , A61F2/70
CPC分类号： G06F3/015 , A61F2/50 , A61F2/68 , A61F2002/704 , A61F2002/7615 , G06N3/061 , G09B19/00 , G09B23/28
摘要： Various embodiments of a biological interface system and related methods are disclosed. The system may include a sensor having a plurality of electrodes for detecting multicellular signals emanating from one or more living cells of a patient, and a processing unit configured to receive the multicellular signals from the sensor and process the multicellular signals to produce a processed signal. The processing unit may be configured to transmit the processed signal to a controlled device that is configured to receive the processed signal. The system may also include a patient training apparatus configured to receive a patient training signal that causes the patient training apparatus to controllably move one or more joints of the patient. The system may be configured to perform an integrated patient training routine to produce the patient training signal, to store a set of multicellular signal data detected during a movement of the one or more joints, and to correlate the set of multicellular signal data to a second set of data related to the movement of the one or more joints.
摘要翻译： 公开了生物界面系统和相关方法的各种实施例。 该系统可以包括具有多个电极的传感器，用于检测从患者的一个或多个活细胞发出的多细胞信号，以及处理单元，被配置为从传感器接收多细胞信号并处理多细胞信号以产生经处理的信号。 处理单元可以被配置为将经处理的信号发送到被配置为接收经处理的信号的受控设备。 该系统还可以包括被配置为接收患者训练信号的患者训练装置，其使得患者训练装置可控制地移动患者的一个或多个关节。 该系统可以被配置为执行综合的患者训练程序以产生患者训练信号，以存储在一个或多个关节的运动期间检测到的一组多细胞信号数据，并将该多组细胞信号数据集合与第二 与一个或多个关节的移动相关的数据集。
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公开(公告)号：US20050267597A1
公开(公告)日：2005-12-01
申请号：US10992111
申请日：2004-11-19
申请人： J. Christopher Flaherty , L. Renee Capachione , Daniel Morris , Abraham Caplan , Maryam Saleh , K. Shane Guillory
发明人： J. Christopher Flaherty , L. Renee Capachione , Daniel Morris , Abraham Caplan , Maryam Saleh , K. Shane Guillory
CPC分类号： A61B5/0031 , A61B5/04001 , A61B2560/0223 , A61B2560/045 , A61B2562/08
摘要： A system and method for a neural interface system with a unique identification code includes a sensor including a plurality of electrodes to detect multicellular signals, an processing unit to process the signals from the sensor into a suitable control signal for a controllable device such as a computer or prosthetic limb. The unique identification code is embedded in one or more discrete components of the system. Internal and external system checks for compatibility and methods of ensuring safe and effective performance of a system with detachable components are also disclosed.
摘要翻译： 一种用于具有唯一识别码的神经接口系统的系统和方法包括：传感器，包括用于检测多细胞信号的多个电极;处理单元，用于将来自传感器的信号处理成用于诸如计算机之类的可控设备的合适的控制信号 或假肢。 唯一的识别码嵌入在系统的一个或多个分立组件中。 还公开了内部和外部系统检查兼容性以及确保具有可拆卸部件的系统的安全和有效性能的方法。
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公开(公告)号：US07280870B2
公开(公告)日：2007-10-09
申请号：US10453785
申请日：2003-06-04
CPC分类号： G02B6/125 , A61B5/0031 , A61B5/04001 , A61B2560/0219 , A61M5/14276 , A61N1/08 , A61N1/372 , A61N1/378 , G02B6/2813 , G02B6/381 , G02B6/4249 , H01L31/105
摘要： According to embodiments of the invention, one or more implants in a body may be connected with optical fibers for transmitting data and/or power to or from the implants. Aspects of the invention related to various embodiments of the actual implant as well as to various embodiments for connecting optical fibers to the implants.
摘要翻译： 根据本发明的实施例，身体中的一个或多个植入物可以与光纤连接，用于将数据和/或动力传送到植入物或从植入物传递。 与实际植入物的各种实施方案相关的本发明的各个方面以及用于将光纤连接到植入物的各种实施方案。
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公开(公告)号：US20200253504A1
公开(公告)日：2020-08-13
申请号：US16758494
申请日：2017-11-01
申请人： Daniel Shen , Brett Herscher , David Krawzsenek , Kyler Connelly , Michael Baker , R. Maxwell Flaherty , J. Christopher Flaherty
发明人： Daniel Shen , Brett Herscher , David Krawzsenek , Kyler Connelly , Michael Baker , R. Maxwell Flaherty , J. Christopher Flaherty
摘要： Systems for characterizing tissue comprise: a tissue probe comprising a plurality of probe electrodes; a signal generator, a controller, and a user interface. The signal generator is in communication with the probe electrodes for delivering a drive signal to at least one probe electrode. The controller receives a recorded signal from one or more probe electrodes, the recorded signal resulting from delivery of the drive signal through tissue proximate the plurality of probe electrodes. The controller is configured to determine patient-to-patient differences when the tissue probe is proximate a known type of patient tissue and/or bodily fluid, and it produces tissue characterization information based on the recorded signal and the patient-to-patient differences. The user interface provides the tissue characterization information to an operator of the system. Methods of characterizing tissue are also provided.
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