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公开(公告)号：US10370504B2
公开(公告)日：2019-08-06
申请号：US15433650
申请日：2017-02-15
Applicant: MODERN MEADOW, INC.
Inventor： Brendan Patrick Purcell , David Thomas Williamson , Francoise Suzanne Marga , Susan J. Schofer , Darryl Miles Cassingham , Stephen M. Spinella , Amy Congdon
IPC: C08J3/24 , C14C13/00 , D04H13/00 , D06P3/32 , C07K14/78 , C14C9/00 , C14C9/02 , D04H1/4382 , D01C3/00 , D06N3/00 , D04H1/00 , D06M15/05 , D01F4/00 , B32B5/26 , D06M15/15 , D06N7/00 , B32B5/02 , B32B7/12 , B32B9/02 , B32B15/02 , B32B15/14 , B32B23/10 , B32B27/12 , B32B29/02 , B32B1/08 , B32B3/26 , D06M101/06 , D06M23/16
Abstract: Described herein is a method for producing a biofabricated material from collagen or collagen-like proteins which are recombinantly produced and which contain substantially no 3-hydroxyproline. The collagen or collagen-like proteins are isolated from animal sources, or produced by recombinant DNA techniques or by chemical synthesis. The collagen or collagen-like proteins are fibrillated, crosslinked, dehydrated and lubricated thus forming the biofabricated material having a substantially uniform network of collagen fibrils.
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公开(公告)号：US11542374B2
公开(公告)日：2023-01-03
申请号：US15433877
申请日：2017-02-15
Applicant: MODERN MEADOW, INC.
Inventor： Brendan Patrick Purcell , David Thomas Williamson , Suzanne Lee , Amy Congdon
IPC: B32B5/26 , D06M15/15 , D06N3/00 , D06N7/00 , D04H13/00 , C08J3/24 , D01F4/00 , B32B5/02 , B32B7/12 , B32B9/02 , B32B15/02 , B32B15/14 , B32B23/10 , B32B27/12 , B32B29/02 , B32B1/08 , B32B3/26 , D04H1/4382 , C14C13/00 , D06P3/32 , C07K14/78 , C14C9/00 , C14C9/02 , D01C3/00 , D04H1/00 , D06M15/05 , D06M23/16 , D06M101/06
Abstract: The invention is directed to a composite material comprising a biofabricated material and a secondary component. The secondary component may be a porous material, such as a sheet of paper, cellulose, or fabric that has been coated or otherwise contacted with the biofabricated material. The biofabricated material comprises a uniform network of crosslinked collagen fibrils and provides strength, elasticity and an aesthetic appearance to the composite material.
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公开(公告)号：US20170233837A1
公开(公告)日：2017-08-17
申请号：US15433693
申请日：2017-02-15
Applicant: MODERN MEADOW, INC.
Inventor： Brendan Patrick PURCELL , David Thomas Williamson , Suzanne Lee , Amy Congdon
CPC classification number: C08J3/24 , B32B1/08 , B32B3/266 , B32B5/022 , B32B5/024 , B32B5/026 , B32B5/26 , B32B7/12 , B32B9/025 , B32B15/02 , B32B15/14 , B32B23/10 , B32B27/12 , B32B29/02 , B32B2250/02 , B32B2250/03 , B32B2250/20 , B32B2250/40 , B32B2250/42 , B32B2255/02 , B32B2255/26 , B32B2262/0207 , B32B2262/0261 , B32B2262/0269 , B32B2262/0276 , B32B2262/0292 , B32B2262/04 , B32B2262/062 , B32B2262/065 , B32B2262/067 , B32B2262/08 , B32B2262/10 , B32B2262/101 , B32B2262/103 , B32B2262/106 , B32B2262/14 , B32B2264/105 , B32B2307/202 , B32B2307/208 , B32B2307/308 , B32B2307/4026 , B32B2307/422 , B32B2307/50 , B32B2307/51 , B32B2307/54 , B32B2307/5825 , B32B2307/708 , B32B2307/7265 , B32B2437/00 , B32B2437/02 , B32B2437/04 , B32B2439/46 , B32B2451/00 , B32B2457/00 , B32B2471/00 , B32B2479/00 , B32B2519/00 , B32B2571/00 , B32B2601/00 , B32B2605/003 , B32B2605/08 , B32B2605/12 , B32B2605/18 , C07K14/78 , C08J2389/06 , C14C9/00 , C14C9/02 , C14C13/00 , D01C3/00 , D01F4/00 , D04H1/00 , D04H1/4382 , D04H13/00 , D06M15/05 , D06M15/15 , D06M23/16 , D06M2101/06 , D06N3/00 , D06N3/0018 , D06N7/0097 , D06N2201/06 , D06N2203/02 , D06P3/32
Abstract: The invention is directed to a composite material comprising a biofabricated material and a secondary component. The secondary component may be a porous material, such as a sheet of paper, cellulose, or fabric that has been coated or otherwise contacted with the biofabricated material. The biofabricated material comprises a uniform network of crosslinked collagen fibrils and provides strength, elasticity and an aesthetic appearance to the composite material.
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公开(公告)号：US11530304B2
公开(公告)日：2022-12-20
申请号：US15433566
申请日：2017-02-15
Applicant: MODERN MEADOW, INC.
Inventor： Brendan Patrick Purcell , David Thomas Williamson , Lixin Dai , Darryl Miles Cassingham , Stephen M. Spinella , Katherine Amy Congdon
IPC: B32B5/26 , D06N3/00 , D06N7/00 , C08J3/24 , D01F4/00 , D06M15/15 , B32B5/02 , B32B7/12 , B32B9/02 , B32B15/02 , B32B15/14 , B32B23/10 , B32B27/12 , B32B29/02 , B32B1/08 , B32B3/26 , D04H1/4382 , C14C13/00 , D04H13/00 , D06P3/32 , C07K14/78 , C14C9/00 , C14C9/02 , D01C3/00 , D04H1/00 , D06M15/05 , D06M23/16 , D06M101/06
Abstract: A biofabricated material comprising a network of crosslinked collagen fibrils produced from recombinant collagen that contains substantially no 3-hydroxyproline residues is disclosed. This material is composed of collagen which is also a major component of natural leather and is produced by a process of fibrillation of collagen molecules into fibrils, crosslinking the fibrils and lubricating the crosslinked fibrils. Unlike natural leathers, this biofabricated material exhibits non-anisotropic (not directionally dependent) physical properties, for example, a sheet of biofabricated material can have substantially the same elasticity or tensile strength when stretched or stressed in different directions. Unlike natural leather, it has a uniform texture that facilitates uniform uptake of dyes and coatings. Aesthetically, it produces a uniform and consistent grain for ease of manufacturability. It can have substantially identical grain, texture and other aesthetic properties on both sides distinct from natural leather where the grain increases from one side (e.g., distal surface) to the other (proximal inner layers).
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公开(公告)号：US11028146B2
公开(公告)日：2021-06-08
申请号：US16125386
申请日：2018-09-07
Applicant: MODERN MEADOW, INC.
Inventor： Lixin Dai , Kristin Ruebling-Jass , David Thomas Williamson
IPC: C12N9/96 , C07K14/78 , D01F4/00 , C07K14/195 , C07K14/245 , C12N9/02 , C12N15/81 , C12N9/04 , C12N9/12 , C12N9/18 , C12N9/90 , C12R1/84 , D01F1/02
Abstract: This invention relates to genetically engineered strains of yeast and methods for producing recombinant protein (e.g., collagen). Recombinant protein of the present invention is used to produce biofabricated leather or a material having leather-like properties containing recombinant or engineered collagen. The yeast strains are engineered to produce ascorbate and/or increased production of α ketoglutarate.
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Patent Agency Ranking
公开(公告)号：US11286354B2
公开(公告)日：2022-03-29
申请号：US15433632
申请日：2017-02-15
Applicant: MODERN MEADOW, INC.
Inventor： Brendan Patrick Purcell , David Thomas Williamson , Francoise Suzanne Marga , Susan J. Schofer , Darryl Miles Cassingham
IPC: C08J3/24 , D01F4/00 , B32B5/26 , D06M15/15 , D06N3/00 , D06N7/00 , B32B5/02 , B32B7/12 , B32B9/02 , B32B15/02 , B32B15/14 , B32B23/10 , B32B27/12 , B32B29/02 , B32B1/08 , B32B3/26 , D04H1/4382 , C14C13/00 , D04H13/00 , D06P3/32 , C07K14/78 , C14C9/00 , C14C9/02 , D01C3/00 , D04H1/00 , D06M15/05 , D06M23/16 , D06M101/06
Abstract: Described herein is a method for producing a biofabricated material from collagen or collagen-like proteins. The collagen or collagen-like proteins are isolated from animal sources or produced by recombinant DNA techniques or by chemical synthesis. The collagen or collagen-like proteins are fibrillated, crosslinked, dehydrated and lubricated thus forming the biofabricated material having a substantially uniform network of collagen fibrils.
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公开(公告)号：US11001679B2
公开(公告)日：2021-05-11
申请号：US16358299
申请日：2019-03-19
Applicant: MODERN MEADOW, INC.
Inventor： Brendan Patrick Purcell , David Thomas Williamson , Lixin Dai , Darryl Miles Cassingham , Stephen M. Spinella
IPC: D06M15/15 , C08J3/24 , D01F4/00 , B32B5/26 , D06N3/00 , D06N7/00 , B32B5/02 , B32B7/12 , B32B9/02 , B32B15/02 , B32B15/14 , B32B23/10 , B32B27/12 , B32B29/02 , B32B1/08 , B32B3/26 , C14C13/00 , D04H13/00 , D06P3/32 , C07K14/78 , C14C9/00 , C14C9/02 , D04H1/4382 , D01C3/00 , D04H1/00 , D06M15/05 , D06M23/16 , D06M101/06
Abstract: A biofabricated material containing a network of crosslinked collagen fibrils is disclosed. This material is composed of collagen which is also a major component of natural leather and is produced by a process of fibrillation of collagen molecules into fibrils, crosslinking the fibrils and lubricating the crosslinked fibrils. Unlike natural leathers, this biofabricated material exhibits non-anisotropic (not directionally dependent) physical properties, for example, a sheet of biofabricated material can have substantially the same elasticity or tensile strength when stretched or stressed in different directions. Unlike natural leather, it has a uniform texture that facilitates uniform uptake of dyes and coatings. Aesthetically, it produces a uniform and consistent grain for ease of manufacturability. It can have substantially identical grain, texture and other aesthetic properties on both sides distinct from natural leather where the grain increases from one side (e.g., distal surface) to the other (proximal inner layers).
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公开(公告)号：US10370505B2
公开(公告)日：2019-08-06
申请号：US15433693
申请日：2017-02-15
Applicant: MODERN MEADOW, INC.
Inventor： Brendan Patrick Purcell , David Thomas Williamson , Suzanne Lee , Amy Congdon
IPC: C08J3/24 , C14C13/00 , D04H13/00 , D06P3/32 , C07K14/78 , C14C9/00 , C14C9/02 , D04H1/4382 , D01C3/00 , D06N3/00 , D04H1/00 , D06M15/05 , D01F4/00 , B32B5/26 , D06M15/15 , D06N7/00 , B32B5/02 , B32B7/12 , B32B9/02 , B32B15/02 , B32B15/14 , B32B23/10 , B32B27/12 , B32B29/02 , B32B1/08 , B32B3/26 , D06M101/06 , D06M23/16
Abstract: The invention is directed to a composite material comprising a biofabricated material and a secondary component. The secondary component may be a porous material, such as a sheet of paper, cellulose, or fabric that has been coated or otherwise contacted with the biofabricated material. The biofabricated material comprises a uniform network of crosslinked collagen fibrils and provides strength, elasticity and an aesthetic appearance to the composite material.
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公开(公告)号：US20190093116A1
公开(公告)日：2019-03-28
申请号：US16125386
申请日：2018-09-07
Applicant: MODERN MEADOW, INC.
Inventor： Lixin Dai , Kristin Ruebling-Jass , David Thomas Williamson
Abstract: This invention relates to genetically engineered strains of yeast and methods, for producing recombinant protein (e.g., collagen). Recombinant protein of the present invention is used to produce biofabricated leather or a material having leather-like properties containing recombinant or engineered collagen. The yeast strains are engineered to produce ascorbate and/or increased production of α ketoglutarate.
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公开(公告)号：US20170233834A1
公开(公告)日：2017-08-17
申请号：US15433650
申请日：2017-02-15
Applicant: MODERN MEADOW, INC
Inventor： Brendan Patrick PURCELL , David Thomas Williamson , Francoise Suzanne Marga , Susan J. Schofer , Darryl Miles Cassingham , Stephen M. Spinella , Amy Congdon
IPC: C14C9/00 , D04H1/4382 , C07K14/78 , C14C9/02 , D06P3/32
CPC classification number: C08J3/24 , B32B1/08 , B32B3/266 , B32B5/022 , B32B5/024 , B32B5/026 , B32B5/26 , B32B7/12 , B32B9/025 , B32B15/02 , B32B15/14 , B32B23/10 , B32B27/12 , B32B29/02 , B32B2250/02 , B32B2250/03 , B32B2250/20 , B32B2250/40 , B32B2250/42 , B32B2255/02 , B32B2255/26 , B32B2262/0207 , B32B2262/0261 , B32B2262/0269 , B32B2262/0276 , B32B2262/0292 , B32B2262/04 , B32B2262/062 , B32B2262/065 , B32B2262/067 , B32B2262/08 , B32B2262/10 , B32B2262/101 , B32B2262/103 , B32B2262/106 , B32B2262/14 , B32B2264/105 , B32B2307/202 , B32B2307/208 , B32B2307/308 , B32B2307/4026 , B32B2307/422 , B32B2307/50 , B32B2307/51 , B32B2307/54 , B32B2307/5825 , B32B2307/708 , B32B2307/7265 , B32B2437/00 , B32B2437/02 , B32B2437/04 , B32B2439/46 , B32B2451/00 , B32B2457/00 , B32B2471/00 , B32B2479/00 , B32B2519/00 , B32B2571/00 , B32B2601/00 , B32B2605/003 , B32B2605/08 , B32B2605/12 , B32B2605/18 , C07K14/78 , C08J2389/06 , C14C9/00 , C14C9/02 , C14C13/00 , D01C3/00 , D01F4/00 , D04H1/00 , D04H1/4382 , D04H13/00 , D06M15/05 , D06M15/15 , D06M23/16 , D06M2101/06 , D06N3/00 , D06N3/0018 , D06N7/0097 , D06N2201/06 , D06N2203/02 , D06P3/32
Abstract: Described herein is a method for producing a biofabricated material from collagen or collagen-like proteins which are recombinantly produced and which contain substantially no 3-hydroxyproline. The collagen or collagen-like proteins are isolated from animal sources, or produced by recombinant DNA techniques or by chemical synthesis. The collagen or collagen-like proteins are fibrillated, crosslinked, dehydrated and lubricated thus forming the biofabricated material having a substantially uniform network of collagen fibrils.
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