摘要:
Compositions and methods for diagnosing, monitoring, or treating cancers. Genes encoding transmembrane proteins that are over-expressed in colon, lung, breast, prostate, liver, stomach, esophagus, or kidney cancer tissues are identified. These transmembrane genes can be used as biological markers for the detection or diagnosis of cancers. These genes can also serve as targets for cancer therapeutics. In addition, these genes can also be used for screening for anti-cancer drugs.
摘要:
The present invention provides novel isolated CRF2-12 polynucleotides and polypeptides encoded by the CRF2-12 polynucleotides. Also provided are the antibodies that immunospecifically bind to a CRF2-12 polypeptide or any derivative (including fusion derivative), variant, mutant or fragment of the CRF2-12 polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the CRF2-12 polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.
摘要:
The present invention relates to a seal oil based lipid emulsion injection, and the main ingredients of which contains 190-210 g/l of refined OMEGA3 seal oil, 11-13 g/l of refined lecithin, 24-26 g/l of glycerol for injection, and balance amount of water. The preparation of the seal oil based lipid emulsion injection comprising the steps of stir and dispersion, high-pressure homogenization, vacuum filtration, antisepsis and encapsulation. The OMEGA3 seal oil lipid based emulsion injections have high content of energy, and thus are highly absorbable to human body, and can not only provide human body with caloricity, but also supply the fatty acids necessary for human body, and can enhance body's immunizing ability, reduce the content of cholesterol, adjust the blood concentration and then be used for anti-inflammation, in particular, it is highly useful for a postoperative patient to restore his strength.
摘要:
A method of etching a substrate is provided. The method of etching a substrate includes transferring a pattern into the substrate using a double patterned amorphous carbon layer on the substrate as a hardmask. Optionally, a non-carbon based layer is deposited on the amorphous carbon layer as a capping layer before the pattern is transferred into the substrate.
摘要:
A multi-channel modular device (10) processes between two fluid streams of different compositions. The device (10) includes a porous body (150) having a first plurality of feed-flow pathways (110) disposed in the body (150) for transporting a first stream (180). A pathway wall (114) surrounds each of the first plurality of feed-flow pathways (110) for processing the first stream (180) into a first composition (1852) and a second composition (1802). At least one feed-flow inlet (1101) is disposed in the body (150) for introducing the first stream (180) into the first plurality of feed-flow pathways (110). At least one feed-flow outlet (1102) is disposed in the body (150) for discharging the remaining first stream containing the second composition (1802). At least one second pathway (210) is disposed in the body (150) for transporting a second stream (280) having a second inlet (2101) and a second outlet (2102). A networked plurality of fluid conduits (152) formed in the porous body (150) provides the flow-conduit for the second stream (280) to sweep the first composition (1852) from each of the first plurality of the feed-flow pathways (110) to the second outlet (2102). A vessel (300) ports the inlets (1101 and 2101) and outlets (1102 and 2102) to provide a second stream flow access and for spacing the body within and away from the inner surfaces of the vessel (300) to provide a gap (310) for access. A partition (350) is disposed in the gap between the body and the vessel for diverting the flow within the gap (310).
摘要:
An improved process for growing carbon nanotubes includes steps of providing a glass substrate that has a porous surface, depositing a catalyst into the pores on the porous surface, and growing carbon nanotubes on the substrate. Desirably, the carbon nanotubes are grown using a chemical vapor deposition technique in which the direction of flow of a carbon precursor gas (and any optional diluent gases) is aligned with the desired direction of growth propagation. The techniques of the invention provide a field emission device having more uniformly aligned carbon nanotubes and/or more uniformly sized carbon nanotubes.
摘要:
A conductive polymer is formed enzymatically in the presence of a polynucleotide template. The method includes combining at least one redox monomer with a polynucleotide template and a redox enzyme, such as horseradish peroxidase, to form a reaction mixture. The monomer aligns along the template before or during the polymerization. Therefore, the polynucleotide template thereby affects the molecular weight and conformation of the conductive polymer. When the conductive polymer is complexed to a polynucleotide duplex, the conformation of the polynucleotide duplex can be modulated by changing the oxidation state of the conductive polymer.
摘要:
Human cell surface molecules CD70 and CD203c are expressed at higher levels in kidney carcinomas, particularly renal cell carcinomas and clear cell renal cell carcinomas, yet are expressed at low levels in normal kidney and other diseased kidney tissue, and at low levels in other tissues. CD70 and CD203c show specificity towards kidney carcinomas, particularly renal cell carcinomas and clear cell renal cell carcinomas and thus can be used as diagnostic markers and therapeutic targets for these diseases. In addition, antibodies or small molecules against these molecules could be used in treatments towards these diseases.
摘要:
A Centralized Authentication & Authorization (CAA) system that prevents unauthorized access to client data using a secure global hashtable residing in the application server in a web services environment. CAA comprises a Service Request Filter (SRF) and Security Program (SP). The SRF intercepts service requests, extracts the service client's identifier from a digital certificate attached to the request, and stores the identifier in memory accessible to service providers. The client identifier is secured by the SP using a key unique to the client identifier. When the web services manager requests the client identifier, the web services manager must present the key to the SP in order to access the client identifier. Thus, the present invention prevents a malicious user from attempting to obtain sensitive data within the application server once the malicious user has gained access past the firewall.
摘要:
A method for controlling etch processes during fabrication of semiconductor devices comprises tests and measurements performed on non-product and product substrates to define an N-parameter CD control graph that is used to calculate a process time for trimming a patterned mask to a pre-determined width. An apparatus for performing such a method.