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公开(公告)号:US20250091051A1
公开(公告)日:2025-03-20
申请号:US18959319
申请日:2024-11-25
Applicant: Essenlix Corporation
Inventor: Stephen Y. Chou , Wei Ding , Ji Qi , Yufan Zhang
IPC: B01L7/00
Abstract: The present invention provides devices, systems, and methods for rapid sample thermal cycle changes for the facilitation of reactions such as but not limited to PCR.
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公开(公告)号:US12181472B2
公开(公告)日:2024-12-31
申请号:US16621185
申请日:2018-06-12
Applicant: Essenlix Corporation
Inventor: Stephen Y. Chou , Wei Ding , Yufan Zhang , Ji Li , Ji Qi , Jun Tian
IPC: G01N33/543 , G06T7/00
Abstract: Among other things, the present invention is related to devices and methods of performing biological and chemical assays, such as but not limited to immunoassays and nucleic assay acid, particularly the homogeneous assay that does not use the step of wash and that is fast (e.g. 60 seconds from dropping a sample to displaying results).
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公开(公告)号:US12151246B2
公开(公告)日:2024-11-26
申请号:US16078356
申请日:2018-02-14
Applicant: Essenlix Corporation
Inventor: Stephen Y. Chou , Wei Ding , Ji Qi , Yufan Zhang
IPC: B01L7/00
Abstract: A device and system for changing the temperature of a fluidic sample includes a first plate and a second plate movable relative to each other into an open configuration and a closed configuration, and spacers having a uniform height. The plates include a sample contact area for contacting the sample and have a configuration for changing the temperature of the sample. In the open configuration the plates are separated, and the sample is capable of being deposited onto the plates. In the closed configuration, the plates are parallel, the plates compress the sample into a layer of uniform thickness that is stagnant relative to the plates, the layer is confined by the sample contact areas of the plates and is regulated by the plates and the spacers, and the plates are configured to change the temperature of the sample at a rate of at least 10° C./sec.
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公开(公告)号:US20240159999A1
公开(公告)日:2024-05-16
申请号:US18539243
申请日:2023-12-13
Applicant: Essenlix Corporation
Inventor: Stephen Y. Chou , Wei Ding , Ji Qi , Yuechang Zhang , Wu Chou , Mingquan Wu , Xing Li , Jun Tian
IPC: G02B21/34 , G01N33/543
CPC classification number: G02B21/34 , G01N33/54386 , G01N33/5094 , G01N2496/05
Abstract: A method of assaying an analyte in a sample is disclosed. The method includes having a sample holder with a sample contact area for contacting a sample with an analyte, having a plurality of calibration structures on the sample contact area of the sample holder, imaging a part of the sample contact area that has the calibration structures, and using an algorithm that includes an image, calibration structures in the image, and artificial intelligence and/or machine learning to identify the analyte and/or determine the analyte concentration.
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公开(公告)号:US11940443B2
公开(公告)日:2024-03-26
申请号:US16964870
申请日:2019-01-25
Applicant: Essenlix Corporation
Inventor: Stephen Y. Chou , Wei Ding , Ji Li , Yufan Zhang
IPC: G01N33/543 , B01L3/00 , G01N21/29 , G01N33/50
CPC classification number: G01N33/54313 , B01L3/502746 , G01N21/29 , G01N33/5005 , B01L2300/0816
Abstract: Among other things, the present invention is related to bio/chemical sampling, sensing, assays and applications.
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公开(公告)号:US11906432B2
公开(公告)日:2024-02-20
申请号:US17268799
申请日:2019-08-23
Applicant: Essenlix Corporation
Inventor: Stephen Y. Chou , Wei Ding , Ji Li , Shengjian Cai , Yufan Zhang , Jia Peng
IPC: G01N21/64 , G01N1/30 , G01N21/76 , G01N33/543
CPC classification number: G01N21/6458 , G01N1/30 , G01N21/76 , G01N33/54373
Abstract: The present invention provides, among other things, devices, kits, apparatus, and methods for rapid homogenous cell staining and imaging. Particularly, in some embodiments, the present invention can immunochemically stain a cell or a tissue in less than 60 seconds without washing. In some embodiments, the present invention stains and observers analyte (protein or nucleic acid) inside a cell in 60 seconds without wash.
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公开(公告)号:US11806717B2
公开(公告)日:2023-11-07
申请号:US17268685
申请日:2019-08-16
Applicant: Essenlix Corporation
Inventor: Stephen Y. Chou , Wei Ding , Ji Qi , Yufan Zhang
CPC classification number: B01L3/5088 , G01N1/2813 , G01N33/492 , B01L2200/022 , B01L2200/025 , B01L2300/0636 , B01L2300/0816 , B01L2300/0829 , B01L2300/0851 , B01L2300/0887 , B01L2300/123 , B01L2400/0481
Abstract: One aspect of the present invention is to provide the device and methods for performing an assay that uses the multiplexing of sample thicknesses on the same plate. The sample thickness multiplexing can offer many information that are unavailable in using a single sample thickness.
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公开(公告)号:USD1003453S1
公开(公告)日:2023-10-31
申请号:US29691071
申请日:2019-05-14
Applicant: Essenlix Corporation
Designer: Stephen Y. Chou , Wei Ding , Ji Qi , Hua Tan
Abstract: FIG. 1 shows a top perspective view of an assay card hinge in an open configuration accordance with the present invention;
FIG. 2 shows a top view thereof;
FIG. 3 shows a bottom view thereof;
FIG. 4 shows a front view thereof;
FIG. 5 shows a rear view thereof;
FIG. 6 shows a right side view thereof;
FIG. 7 shows a left side view thereof;
FIG. 8 shows a top perspective view of the assay card hinge in a closed configuration accordance with the present invention;
FIG. 9 shows a top view thereof;
FIG. 10 shows a bottom view thereof;
FIG. 11 shows a front view thereof;
FIG. 12 shows a rear view thereof;
FIG. 13 shows a right side view thereof; and
FIG. 14 shows a left side view thereof.
The dashed broken lines in the drawings depict environmental subject matter and form no part of the claimed design.
The dot-dash-dot broken lines in the drawings depict the boundaries of the claimed subject matter and form no part of the claimed design.-
公开(公告)号:US20230340559A1
公开(公告)日:2023-10-26
申请号:US18214811
申请日:2023-06-27
Applicant: Essenlix Corporation
Inventor: Stephen Y. Chou , Wei Ding
CPC classification number: C12Q1/18 , G16H40/67 , G16H10/40 , G16H30/40 , G16H80/00 , C12M41/46 , G01N1/30 , G06T7/0016 , G06T2207/10016 , G06T2207/30024
Abstract: The present invention provides devices, systems, and methods, for performing biological and chemical assays.
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公开(公告)号:US11796428B2
公开(公告)日:2023-10-24
申请号:US17592410
申请日:2022-02-03
Applicant: Essenlix Corporation
Inventor: Stephen Y. Chou , Wei Ding , Ji Qi , Yufan Zhang
IPC: G01N1/28 , G01N33/483
CPC classification number: G01N1/2813 , G01N33/4833 , G01N1/286 , G01N2001/282
Abstract: The present invention relates to the methods, devices, and systems that make bio/chemical sensing (including, not limited to, immunoassay, nucleic assay, electrolyte analysis, etc.) faster, more sensitive, less steps, easy to perform, smaller amount of samples required, less or reduced (or no) needs for professional assistance, and/or lower cost, than many current sensing methods and devices. The present invention also allows a test performed by a smartphone.
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