公开(公告)号：US11717550B2

公开(公告)日：2023-08-08

申请号：US17546272

申请日：2021-12-09

Applicant: Sang-Kuk Lee ,  Yong-Suk Lee

Inventor： Sang-Kuk Lee ,  Yong-Suk Lee

IPC: A61K36/42 ,  A61P1/14 ,  A61K9/00 ,  A61K9/08 ,  A61K33/04 ,  A61K33/26 ,  A61K33/32 ,  A61K36/22 ,  A23L2/00 ,  A23L2/38 ,  A23L33/00

CPC classification number: A61K36/42 ,  A23L2/00 ,  A61K9/0095 ,  A61K9/08 ,  A61K33/04 ,  A61K33/26 ,  A61K33/32 ,  A61K36/22 ,  A61P1/14 ,  A23L2/38 ,  A23L33/00

Abstract: A method for preparing drinking water for livestock includes mixing 2.5 to 5.0 WT % of tourmaline and 2.5 to 5.0 WT % of illite as natural minerals in powder form of 2 to 3 μm with 90 to 95 WT % of water to produce a mixed solution, and maintaining the mixed solution for 5 to 7 hours at room temperature, and removing the tourmaline powders and illite powders to produce leachate; mixing 15 to 25 WT % of detoxified sulfur in powder form of 2 to 3 μm, 10 to 25 WT % of Rrhus verniciflua Stokes extract, and 10 to 25 WT % of Momordicae Semen extract with 25 to 65 WT % of the leachate to produce a liquid mixture, and maintaining the liquid mixture for 12 hours; and mixing 150 to 250 ml of the liquid mixture with 20 l of water and maintaining the liquid mixture for 6 to 7 hours for amplification.

公开(公告)号：US20230233599A1

公开(公告)日：2023-07-27

申请号：US17936361

申请日：2022-09-28

Applicant: RHA INVESTMENT LIMITED

Inventor： Shawn J. Green

IPC: A61K33/00 ,  A61K36/74 ,  A61K36/185 ,  A61K31/375 ,  A61K31/51 ,  A61K31/519 ,  A61K31/714 ,  A61K33/06 ,  A61K47/38 ,  A61K47/02 ,  A61K47/12 ,  A23L33/00 ,  A23L33/105 ,  A23L33/15 ,  A23L33/16 ,  A61K36/21 ,  A61K9/20 ,  A61K47/46 ,  A61K9/00

CPC classification number: A61K33/00 ,  A61K36/74 ,  A61K36/185 ,  A61K31/375 ,  A61K31/51 ,  A61K31/519 ,  A61K31/714 ,  A61K33/06 ,  A61K47/38 ,  A61K47/02 ,  A61K47/12 ,  A23L33/30 ,  A23L33/105 ,  A23L33/15 ,  A23L33/16 ,  A61K36/21 ,  A61K9/2068 ,  A61K47/46 ,  A61K9/2054 ,  A61K9/0095 ,  A61K9/0056 ,  A23V2002/00

Abstract: Compositions and methods for improving nitric oxide levels in a subject, comprising administering to a subject, a composition comprising dietary nitrate derived from potassium nitrate, beet root (whole plant, powder, plant extract), and/or nitrate-rich leafy green portions (whole plant, powder, plant extract) that improve functional nitric oxide levels in subjects as shown by increasing salivary bioconversion of nitrate to nitrite, a necessary a required step for nitric oxide mediated health benefits. The disclosed novel compositions improve cardiac health, lowers blood pressure, intraocular pressure, and LDL and restores nitric oxide mediated cardiovascular benefits, including but not limited, restoring endothelium function and improving flow mediated dilation.

公开(公告)号：US20230225999A1

公开(公告)日：2023-07-20

申请号：US18001889

申请日：2021-06-18

Applicant: SOCIETE DES PRODUITS NESTLE S.A.

Inventor： CLARA LUCIA GARCIA-RODENAS ,  JANE MEA M NATIVIDAD ,  ANDREAS RYTZ

IPC: A61K31/19 ,  A61P1/00 ,  A23L33/00 ,  A23L33/10

CPC classification number: A61K31/19 ,  A61P1/00 ,  A23L33/40 ,  A23L33/10

Abstract: The present invention relates to nutritional compositions comprising 3-hydroxybutyric acid for use in improving gastrointestinal barrier. In particular, the present invention relates to improving the gastrointestinal barrier in an individual, preferably in an infant or a child.

公开(公告)号：US20230217939A1

公开(公告)日：2023-07-13

申请号：US18185049

申请日：2023-03-16

Applicant: Prolacta Bioscience, Inc.

Inventor： Joseph FOURNELL ,  Scott EAKER ,  Scott ELSTER ,  David J. RECHTMAN

IPC: A23C9/20 ,  A23C9/142 ,  A23C9/148 ,  A23C9/158 ,  A61K35/20 ,  A23C3/02 ,  A23L33/00 ,  A23C9/152

CPC classification number: A23C9/206 ,  A23C9/1422 ,  A23C9/148 ,  A23C9/158 ,  A61K35/20 ,  A23C3/02 ,  A23L33/40 ,  A23C9/1522 ,  A23C9/1427 ,  A23V2002/00

Abstract: This disclosure features human milk permeates and compositions containing the same obtained from fractionated whole human milk. The oligosaccharide rich permeate and permeate compositions of the present invention are useful as nutritional supplements for pre-term and full term infants, for establishing or maintaining gut flora and for treating the symptoms of inflammatory bowel disease.

公开(公告)号：US20230201282A1

公开(公告)日：2023-06-29

申请号：US17996501

申请日：2021-01-29

Applicant: ATOGEN CO., LTD.

Inventor： Hae-Jeung LEE ,  Eun-Jung PARK ,  Ji-Hee KANG ,  Hyun-Guh BAEK ,  Gun-Seok PARK

IPC: A61K35/747 ,  A61P3/04 ,  A61P1/16 ,  A61P3/06 ,  A23L33/00 ,  A23L33/135

CPC classification number: A61K35/747 ,  A61P3/04 ,  A61P1/16 ,  A61P3/06 ,  A23L33/40 ,  A23L33/135 ,  A61K2035/115

Abstract: Provided is a composition for preventing and treating lipid-related metabolic diseases, the composition comprising, as an active ingredient, Lactobacillus plantarum ATG-K2 or Lactobacillus plantarum ATG-K6 isolated from fermented vegetables.

公开(公告)号：US20230201279A1

公开(公告)日：2023-06-29

申请号：US17692414

申请日：2022-03-11

Applicant: GenMont Biotech Incorporation

Inventor： Wan-Hua Tsai ,  Wen-Wei Chang ,  Chia-Hsuan Chou ,  I-Jen Wang ,  Wen-Ling Yeh ,  Jhih-Hua Jhong ,  Tzong-Yi Lee

IPC: A61K35/747 ,  A61P37/08 ,  A23L33/00 ,  A23L33/135

CPC classification number: A61K35/747 ,  A61P37/08 ,  A23L33/40 ,  A23L33/135 ,  A23Y2220/63 ,  A23V2002/00

Abstract: The invention provides an extracellular vesicle and a nucleotide fragment isolated from Lactobacillus paracasei GM-080 with the deposition number BCRC 910220 and CCTCC M 204012 and use thereof. The invention also relates to a method for modulating immune function comprising administering a composition including the extracellular vesicle and the nucleotide fragment.

公开(公告)号：US20230201253A1

公开(公告)日：2023-06-29

申请号：US18117321

申请日：2023-03-03

Applicant: Juan Carlos Parodi ,  Samuel Fernandez ,  Scott R. Miller

Inventor： Juan Carlos Parodi ,  Samuel Fernandez ,  Scott R. Miller

IPC: A61K33/00 ,  A23L33/19 ,  A23L33/00 ,  A23L33/175 ,  A23L33/16 ,  A23L33/125 ,  A23L33/15 ,  A61P3/12 ,  A61B5/11 ,  A61B5/00 ,  A61K9/00 ,  A61K31/198 ,  A61K31/405 ,  A61K31/7004 ,  A61K38/00 ,  A61K47/10 ,  A61K47/36 ,  A61K47/42

CPC classification number: A61K33/00 ,  A23L33/15 ,  A23L33/16 ,  A23L33/19 ,  A23L33/30 ,  A23L33/40 ,  A23L33/125 ,  A23L33/175 ,  A61B5/1118 ,  A61B5/4875 ,  A61B5/6887 ,  A61B5/7275 ,  A61K9/0053 ,  A61K31/198 ,  A61K31/405 ,  A61K31/7004 ,  A61K38/00 ,  A61K47/10 ,  A61K47/36 ,  A61K47/42 ,  A61P3/12 ,  A23V2002/00 ,  A61B5/026 ,  A61B5/0082

Abstract: Systems and methods for administering one or more hydration compositions to an individual to improve vascular health are provided. A system comprises a hydration composition delivery element and a sensor operatively coupled to the hydration composition delivery element. The sensor is configured to determine one or more of the intake of fluids, the amount of fluid discharged, the activity level of the patient, or level of hydration of the patient based on the level of fluid in the hydration composition delivery element. The system further includes a monitoring system which, based on a signal received from the sensor, provides an indication of one or more of the need to intake fluid, the identity of a specific hydration composition of a plurality of hydration compositions to be consumed or an amount of a hydration composition to be consumed.

公开(公告)号：US20230190839A1

公开(公告)日：2023-06-22

申请号：US17925842

申请日：2021-05-18

Applicant: GYNOV ,  S.P.M.D.

Inventor： PIERRE-YVES MOUSSET

IPC: A61K36/064 ,  A61P15/08 ,  A61K31/05 ,  A61K36/9066 ,  A61K31/733 ,  A61K33/30 ,  A61K31/121 ,  A61K36/28 ,  A23L33/00 ,  A23L33/105 ,  A23L33/14 ,  A23L33/125 ,  A23L33/15 ,  A23L33/16 ,  A23L33/135

CPC classification number: A61K36/064 ,  A61P15/08 ,  A61K31/05 ,  A61K36/9066 ,  A61K31/733 ,  A61K33/30 ,  A61K31/121 ,  A61K36/28 ,  A23L33/40 ,  A23L33/105 ,  A23L33/14 ,  A23L33/125 ,  A23L33/15 ,  A23L33/16 ,  A23L33/135

Abstract: The present invention relates to the use of a combination of a yeast of the species Saccharomyces cerevisiae, resveratrol and a curcuma extract, for use in the management of a subject who has endometriosis or is susceptible to endometriosis. The combination according to the invention may be used in the treatment or prevention of endometriotic lesions in a subject who has endometriosis or is susceptible to endometriosis, for example to slow the development or to reduce the endometriotic lesions. It may also be used in the treatment or prevention of one or more symptoms or disorders associated with endometriosis. The invention also relates to pharmaceutical or nutraceutical compositions and kits based on said combination.

公开(公告)号：US20230183767A1

公开(公告)日：2023-06-15

申请号：US17916695

申请日：2021-04-01

Applicant: Zimitech, Inc.

Inventor： Jingjing Liu ,  James Harrison Doudna Cate

IPC: C12P19/18 ,  C12N9/10 ,  C12N9/12 ,  C12N9/90 ,  A23L33/135 ,  A23L33/125 ,  A23L33/00 ,  A23K10/18 ,  A23K20/163

CPC classification number: C12P19/18 ,  C12N9/1051 ,  C12N9/1085 ,  C12Y205/01056 ,  C12N9/1081 ,  C12Y204/99001 ,  C12Y204/99004 ,  C12N9/1241 ,  C12Y207/07043 ,  C12N9/90 ,  C12Y501/03008 ,  A23L33/135 ,  A23L33/125 ,  A23L33/40 ,  A23K10/18 ,  A23K20/163

Abstract: Disclosed herein are genetically modified microorganisms and related methods for the enhanced production and export of oligosaccharides. The microorganisms described herein express major facility superfamily proteins such as CDT-1, which allows for the export of oligosaccharides. Variants of CDT-1 exhibit higher activity regarding oligosaccharide export. The microorganisms described herein express formation enzymes for the production of oligosaccharides. Means to export oligosaccharides into the growth medium are provided herein.

公开(公告)号：US20230183665A1

公开(公告)日：2023-06-15

申请号：US17924704

申请日：2021-02-10

Applicant: TEIKYO UNIVERSITY

Inventor： Jinichiro KOGA ,  Hisakazu YAMANE ,  Koji MIYAMOTO ,  Makoto YAZAWA ,  Tomoyoshi KUBOTA

IPC: C12N9/24 ,  C12N15/70 ,  C12P13/02 ,  A23L33/185 ,  A23L33/115 ,  A23L33/00

CPC classification number: C12N9/2402 ,  C12Y302/01045 ,  C12N15/70 ,  C12P13/02 ,  A23L33/185 ,  A23L33/115 ,  A23L33/40 ,  A61K38/00

Abstract: Provided is a protein having glucocerebrosidase activity and further having thermostability. The object is attained by a protein which is derived from a plant, belongs to glycoside hydrolase family 1 (GH1), and has glucocerebrosidase activity.