公开(公告)号：US20170165023A1

公开(公告)日：2017-06-15

申请号：US15444252

申请日：2017-02-27

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Eric Allan Larson ,  Rajiv Shah

IPC: A61B50/30 ,  A61B5/1486 ,  A61M5/00 ,  A61L2/08 ,  B65B55/16 ,  B65B7/16 ,  B65D75/32 ,  B65D65/38 ,  A61B5/145 ,  B65B5/04

CPC classification number: A61B50/3001 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/14865 ,  A61B2050/0065 ,  A61B2560/063 ,  A61B2562/12 ,  A61B2562/125 ,  A61B2562/242 ,  A61L2/08 ,  A61L2/087 ,  A61M5/003 ,  B65B5/04 ,  B65B7/16 ,  B65B7/2842 ,  B65B55/02 ,  B65B55/16 ,  B65D65/38 ,  B65D75/326 ,  B65D77/26

Abstract: A product allows gaseous manufacturing by-products to be vented from the inside a sealed package tray. An exemplary method for packaging a device includes sealing the device inside a package tray with a gas-permeable sealing material, resulting in a sealed package tray. The sealing material allows volatile substances to vent from inside the sealed package tray to outside the sealed package tray.

公开(公告)号：US09616165B2

公开(公告)日：2017-04-11

申请号：US14788668

申请日：2015-06-30

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Eric Allan Larson ,  Rajiv Shah

IPC: A61M5/00 ,  B65D77/26 ,  A61B5/145 ,  A61L2/08 ,  B65B55/02 ,  B65B5/04 ,  B65B7/28 ,  A61B5/1486 ,  B65D65/38

CPC classification number: A61B50/3001 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/14865 ,  A61B2050/0065 ,  A61B2560/063 ,  A61B2562/12 ,  A61B2562/125 ,  A61B2562/242 ,  A61L2/08 ,  A61L2/087 ,  A61M5/003 ,  B65B5/04 ,  B65B7/16 ,  B65B7/2842 ,  B65B55/02 ,  B65B55/16 ,  B65D65/38 ,  B65D75/326 ,  B65D77/26

Abstract: A glucose sensor product maintains the sterility of the glucose sensor while allowing gaseous manufacturing by-products to be vented from the inside of the glucose sensor package. An exemplary glucose sensor product includes a plastic package tray and a glucose sensor assembly in the plastic package tray. The glucose sensor assembly includes an electrochemical sensor with glucose oxidase enzyme, a sensor base formed at least in part from plastic, a sensor mounting pedestal formed at least in part from plastic, and a sensor introducer formed at least in part from plastic. The glucose sensor product also includes a microbial barrier material coupled to the plastic package tray to seal the glucose sensor assembly in the plastic package tray. The microbial barrier material maintains sterility of the glucose sensor assembly while venting substances outgassed from the plastic package tray, the sensor base, the sensor mounting pedestal, and the sensor introducer.

公开(公告)号：US09579066B2

公开(公告)日：2017-02-28

申请号：US14539855

申请日：2014-11-12

Applicant: Medtronic MiniMed, Inc.

Inventor： Rebecca K. Gottlieb ,  Ying Luo ,  Raghavendhar Gautham ,  Bradley Liang ,  Anirban Roy ,  Kenneth W. Cooper ,  Rajiv Shah ,  Barry Keenan

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1495 ,  A61M5/172

CPC classification number: A61B5/7221 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/1473 ,  A61B5/1495 ,  A61B5/4839 ,  A61B5/6849 ,  A61B5/7275 ,  A61B5/743 ,  A61M5/1723 ,  A61M2005/1726 ,  A61M2205/3303 ,  A61M2230/201

Abstract: Disclosed are a system and method for determining a metric and/or indicator of a reliability of a blood glucose sensor in providing glucose measurements. In one aspect, the metric and/or indicator may be computed based, at least in part, on an observed trend associated with signals generated by the blood glucose sensor.

Abstract translation: 公开了一种用于在提供葡萄糖测量中确定血糖传感器的可靠性的度量和/或指标的系统和方法。 在一个方面，可以至少部分地基于与由血糖传感器产生的信号相关联的观察趋势来计算度量和/或指示符。

公开(公告)号：US20160320338A1

公开(公告)日：2016-11-03

申请号：US15207064

申请日：2016-07-11

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Jenn-Hann Larry Wang ,  Michael E. Miller ,  Raghavendhar Gautham ,  Yiwen Li ,  Rajiv Shah

IPC: G01N27/416 ,  A61B5/145 ,  G01N33/66 ,  G01R35/00 ,  G01N27/02 ,  A61B5/1495 ,  A61M5/172

CPC classification number: A61B5/1495 ,  A61B5/0537 ,  A61B5/0538 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/1459 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/4839 ,  A61B5/6849 ,  A61B5/6852 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7225 ,  A61B5/7242 ,  A61B5/746 ,  A61B2562/0214 ,  A61B2562/04 ,  A61M5/14244 ,  A61M5/14276 ,  A61M5/1582 ,  A61M5/1723 ,  A61M2005/1726 ,  G01N27/026 ,  G01N27/028 ,  G01N27/416 ,  G01N27/4163 ,  G01N33/49 ,  G01N33/66 ,  G01N33/96 ,  G01R35/00 ,  G01R35/005

Abstract: A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.

公开(公告)号：US09480796B2

公开(公告)日：2016-11-01

申请号：US14313098

申请日：2014-06-24

Applicant: Medtronic MiniMed, Inc.

Inventor： Timothy J. Starkweather ,  Ronald J. Lebel ,  Rajiv Shah ,  Michael E. Miller

IPC: A61M5/172 ,  G06F19/00 ,  A61M5/142

CPC classification number: A61M5/1723 ,  A61M5/172 ,  A61M2005/14208 ,  A61M2230/201 ,  G06F19/00 ,  G06F19/3468 ,  G16H50/30

Abstract: A system and method for providing closed loop infusion formulation delivery which accurately calculates a delivery amount based on a sensed biological state by adjusting an algorithm's programmable control parameters. The algorithm calculates a delivery amount having proportional, derivative, and basal rate components. The control parameters may be adjusted in real time to compensate for changes in a sensed biological state that may result from daily events. Safety limits on the delivery amount may be included in the algorithm. The algorithm may be executed by a computing element within a process controller for controlling closed loop infusion formulation delivery. The biological state is sensed by a sensing device which provides a signal to the controller. The controller calculates an infusion formulation delivery amount based on the signal and sends commands to an infusion formulation delivery device which delivers an amount of infusion formulation determined by the commands.

公开(公告)号：US20160252473A1

公开(公告)日：2016-09-01

申请号：US15154560

申请日：2016-05-13

Applicant: Medtronic MiniMed, Inc.

Inventor： Ning Yang ,  Raghavendhar Gautham ,  Bradley C. Liang ,  Rajiv Shah

IPC: G01N27/02 ,  G01N27/416 ,  A61B5/1473 ,  A61B5/00 ,  A61B5/1495 ,  A61B5/145

CPC classification number: G01N27/4163 ,  A61B5/0537 ,  A61B5/0538 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/1459 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/4839 ,  A61B5/6849 ,  A61B5/6852 ,  A61B5/7203 ,  A61B5/7221 ,  A61B5/7225 ,  A61B5/7242 ,  A61B5/746 ,  A61B2562/0214 ,  A61B2562/04 ,  A61M5/14244 ,  A61M5/14276 ,  A61M5/1582 ,  A61M5/1723 ,  A61M2005/1726 ,  G01N27/026 ,  G01N27/028 ,  G01N27/416 ,  G01N33/49 ,  G01N33/66 ,  G01N33/96 ,  G01R35/00 ,  G01R35/005

Abstract: A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.

公开(公告)号：US20160228042A9

公开(公告)日：2016-08-11

申请号：US13657642

申请日：2012-10-22

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Xiaolong Li ,  Brian T. Kannard ,  Rajiv Shah

IPC: A61B5/145 ,  A61M5/172 ,  A61B5/00 ,  A61B5/1495 ,  A61B5/1486

CPC classification number: A61B5/14532 ,  A61B5/1451 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/4839 ,  A61B5/6849 ,  A61M5/1723

Abstract: Subject matter disclosed herein relates to monitoring and/or controlling levels of an analyte in bodily fluid. In particular, estimation of a concentration of the analyte in a first physiological compartment based upon observations of a concentration of the analyte in a second physiological compartment may account for a latency in transporting the analyte between the first and second physiological compartments.

公开(公告)号：US20150331419A1

公开(公告)日：2015-11-19

申请号：US14281773

申请日：2014-05-19

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Keith Nogueira ,  Xiaolong Li ,  Rajiv Shah ,  Brian T. Kannard

IPC: G05B23/00

CPC classification number: G05B23/00 ,  A61M5/14244 ,  A61M5/1723 ,  A61M2205/70 ,  A61M2205/702 ,  A61M2230/201

Abstract: Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device capable of delivering fluid to a user involves determining one or more signal characteristics associated with a subset of the measurements corresponding to a monitoring period, determining a reliability metric for the monitoring period based on the one or more signal characteristics, and providing indication of a maintenance condition when the reliability metric violates a threshold.

Abstract translation: 提供输液系统，输液装置和相关操作方法。 操作能够向用户输送流体的输注装置的示例性方法包括确定与对应于监测周期的测量的子集相关联的一个或多个信号特征，基于一个或多个信号确定监测周期的可靠性度量 特性，并且当可靠性度量违反阈值时提供维护条件的指示。

公开(公告)号：US20150272486A1

公开(公告)日：2015-10-01

申请号：US14686653

申请日：2015-04-14

Applicant: Medtronic Minimed, Inc.

Inventor： Bradley Liang ,  Kenneth W. Cooper ,  Raghavendhar Gautham ,  Rajiv Shah

IPC: A61B5/1495 ,  A61B5/00 ,  A61M5/172 ,  A61B5/145

CPC classification number: A61B5/1495 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14532 ,  A61B5/14865 ,  A61B5/4839 ,  A61B5/6849 ,  A61B5/7221 ,  A61B5/746 ,  A61B2560/0276 ,  A61M5/14248 ,  A61M5/1723 ,  A61M2205/50 ,  A61M2230/201

Abstract: Disclosed are methods, apparatuses, etc. for glucose sensor signal reliability analysis.

Abstract translation: 公开了葡萄糖传感器信号可靠性分析的方法，装置等。

公开(公告)号：US20150073244A1

公开(公告)日：2015-03-12

申请号：US14539855

申请日：2014-11-12

Applicant: Medtronic MiniMed, Inc.

Inventor： Rebecca K. Gottlieb ,  Ying Luo ,  Raghavendhar Gautham ,  Bradley Liang ,  Anirban Roy ,  Kenneth W. Cooper ,  Rajiv Shah ,  Barry Keenan

IPC: A61B5/00 ,  A61B5/1495 ,  A61M5/172 ,  A61B5/145

CPC classification number: A61B5/7221 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/1473 ,  A61B5/1495 ,  A61B5/4839 ,  A61B5/6849 ,  A61B5/7275 ,  A61B5/743 ,  A61M5/1723 ,  A61M2005/1726 ,  A61M2205/3303 ,  A61M2230/201

Abstract: Disclosed are a system and method for determining a metric and/or indicator of a reliability of a blood glucose sensor in providing glucose measurements. In one aspect, the metric and/or indicator may be computed based, at least in part, on an observed trend associated with signals generated by the blood glucose sensor.

Abstract translation: 公开了一种用于在提供葡萄糖测量中确定血糖传感器的可靠性的度量和/或指标的系统和方法。 在一个方面，可以至少部分地基于与由血糖传感器产生的信号相关联的观察趋势来计算度量和/或指示符。