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    Process for producing fermented breads comprising rice flour as the main component
    141.
    发明授权
    Process for producing fermented breads comprising rice flour as the main component 失效
    以米粉为主要成分的发酵面包的制造方法

    公开(公告)号：US07815952B2

    公开(公告)日：2010-10-19

    申请号：US10502600

    申请日：2003-01-31

    申请人： Susumu Inoue ,  Kanou Takeuchi

    发明人： Susumu Inoue ,  Kanou Takeuchi

    IPC分类号： A21D13/04

    CPC分类号： A21D2/265 ,  A21D2/18 ,  A21D2/181 ,  A21D2/186 ,  A21D10/02 ,  A21D13/04 ,  A21D13/047 ,  A21D13/40 ,  A21D13/80

    摘要： A process is provided for producing bakery products using rice flour as a major ingredient, which products have improved qualities, such as appearance, crumb, taste, and shelf life as well as satisfactory handleability, as well as excellent qualities. Premixed flours containing rice flour, gluten and a saccharide such as an oligosaccharide or a sugar alcohol, are provided for making these bakery products. Fermented doughs for making the bakery products from the premix are also provided.

    摘要翻译： 提供了使用米粉作为主要成分生产面包店产品的方法，该产品具有改善的品质，例如外观，面包屑，味道和保质期以及令人满意的可操作性以及优异的品质。 提供含有米粉，麸质和糖类如低聚糖或糖醇的预混粉，用于制造这些烘焙产品。 还提供用于从预混物制造面包店产品的发酵面团。

    Peptide Vaccine for Inducing the Production of Anti-Amyloid ß-Peptide Antibody
    142.
    发明申请
    Peptide Vaccine for Inducing the Production of Anti-Amyloid ß-Peptide Antibody 失效
    用于诱导抗淀粉样蛋白β肽抗体生产的肽疫苗

    公开(公告)号：US20100062011A1

    公开(公告)日：2010-03-11

    申请号：US12280535

    申请日：2007-02-16

    申请人： Akira Yano

    发明人： Akira Yano

    IPC分类号： A61K39/00 ,  C07K14/00 ,  C07H21/04 ,  A61P25/28

    CPC分类号： A61K39/0008 ,  A61K2039/543 ,  A61K2039/55516 ,  A61K2039/55544 ,  A61K2039/6037 ,  C07K14/005 ,  C07K14/4711 ,  C07K2319/00 ,  C12N2740/16222

    摘要： An object of the present invention is to provide a peptide vaccine for preventing and/or treating diseases caused by amyloid β-peptide, such as Alzheimer's disease. The present invention solves the above object by providing a peptide vaccine constructed by inserting a peptide having an amino acid sequence of a cell attachment motif of a cell adhesive molecule to a peptide which consists of a peptide having an amino acid sequence of multiagretope type T-cell epitope, which has been generated immunological memory, or a peptide including the same; an linker peptide; and a peptide having an amino acid sequence of a B cell epitope which is a specific region of amyloid β-peptide or a peptide including the same.

    摘要翻译： 本发明的目的是提供一种用于预防和/或治疗由淀粉样蛋白和诸如阿尔茨海默病等引起的疾病的肽疫苗。 本发明通过提供通过将具有细胞粘附分子的细胞附着基序的氨基酸序列的肽插入到由具有多重靶向型T-氨基酸的氨基酸序列的肽组成的肽而构成的肽疫苗来解决上述目的， 已经产生免疫记忆的细胞表位或包含其的肽; 接头肽; 以及具有B细胞表位的氨基酸序列的肽，所述B细胞表位是淀粉样蛋白的特异性区域或包含该氨基酸的肽。

    Cyanine dye
    143.
    发明授权
    Cyanine dye 失效
    花青染料

    公开(公告)号：US07632945B2

    公开(公告)日：2009-12-15

    申请号：US10565592

    申请日：2004-07-21

    申请人： Akira Shinpo ,  Yoshimi Takahashi ,  Kentaro Yano ,  Yasushi Aizawa

    发明人： Akira Shinpo ,  Yoshimi Takahashi ,  Kentaro Yano ,  Yasushi Aizawa

    IPC分类号： C07F1/08 ,  C07D213/89 ,  C07F15/00

    CPC分类号： C09B69/06 ,  C09B23/00 ,  C09B23/0016 ,  C09B23/0066 ,  C09B23/086

    摘要： An objective of this invention is to extend the range of choosing organic dye compounds as light-absorbing agent in a variety of fields of, for example, information storage, information display, solar energy generation, electric machinery apparatus, electric communicating apparatus, optical apparatus, cloth, building/bedding/decorating product, sanitary and health goods, and agricultural material by providing an organic dye compound which is superior in light-absorbing property, light resistance, and solubility in the near-infrared region: The objective is attainable by providing a cyanine dye that bears within the same molecule a plurality of cyanine dye skeletons bound to a divalent group(s) and an organometallic complex as counter ion, as well as substantially absorbing a light with a wavelength longer than 700 nm.

    摘要翻译： 本发明的目的是在例如信息存储，信息显示，太阳能发电，电机装置，电通信装置，光学装置等各种领域中扩大选择有机染料化合物作为光吸收剂的范围 ，布，建筑物/床上用品/装饰品，卫生用品和农用材料，通过提供在近红外区域的光吸收性，耐光性和溶解性优异的有机染料化合物。该目的可通过 提供在相同分子内具有与二价基团结合的多个花青染料骨架和作为抗衡离子的有机金属络合物的花青染料，以及基本上吸收波长长于700nm的光。

    Cyanine dyes
    145.
    发明授权
    Cyanine dyes 失效
    花青染料

    公开(公告)号：US07402375B2

    公开(公告)日：2008-07-22

    申请号：US10438839

    申请日：2003-05-16

    申请人： Chiaki Kasada ,  Yasushi Aizawa ,  Toshio Kawata ,  Shigeo Yasui

    发明人： Chiaki Kasada ,  Yasushi Aizawa ,  Toshio Kawata ,  Shigeo Yasui

    IPC分类号： G11B7/24

    CPC分类号： C09B69/045 ,  C09B23/04 ,  C09B69/02 ,  G11B7/244 ,  G11B7/247 ,  G11B7/2472 ,  G11B7/249 ,  G11B7/2492 ,  G11B7/2531 ,  Y10S430/146

    摘要： The present invention provides organic dye compounds having their absorption maxima in a region ranging from the ultraviolet region to a relatively short wavelength visible region and uses thereof. The present invention provides specific monomethine cyanine dyes, light absorbents and optical recording media comprising the monomethine cyanine dyes, and a process for producing the monomethine cyanine dyes which comprises a step of reacting a quaternary ammonium salt of nitrogen atom-containing heterocyclic compound having a reactive methyl group with a quaternary ammonium salt of nitrogen atom-containing heterocyclic compound having an appropriate leaving group.

    摘要翻译： 本发明提供了在从紫外线区域到相当短的波长可见区域的范围内具有最大吸收的有机染料化合物及其用途。 本发明提供了特定的单甲氰基染料，光吸收剂和包含单甲基花青染料的光学记录介质，以及制备单甲基花青染料的方法，该方法包括使具有反应性的含氮原子杂环化合物的季铵盐 甲基与具有适当离去基团的含氮原子杂环化合物的季铵盐。

    alpha-isomaltosylglucosaccharide-forming enzyme, process and uses of the same
    146.
    发明申请
    alpha-isomaltosylglucosaccharide-forming enzyme, process and uses of the same 有权
    α-异麦芽糖基葡萄糖形成酶，其工艺和用途

    公开(公告)号：US20080003651A1

    公开(公告)日：2008-01-03

    申请号：US11797932

    申请日：2007-05-09

    申请人： Michio Kubota ,  Keiji Tsusaki ,  Takanobu Higashiyama ,  Shigeharu Fukuda ,  Toshio Miyake

    发明人： Michio Kubota ,  Keiji Tsusaki ,  Takanobu Higashiyama ,  Shigeharu Fukuda ,  Toshio Miyake

    IPC分类号： C12P19/04

    CPC分类号： A23G1/40 ,  A21D2/181 ,  A23C9/005 ,  A23C9/1307 ,  A23C9/1544 ,  A23C9/156 ,  A23G3/42 ,  A23G4/10 ,  A23G9/34 ,  A23L2/60 ,  A23L15/00 ,  A23L15/20 ,  A23L27/30 ,  A23L33/10 ,  A23L33/21 ,  A61K8/60 ,  A61K8/66 ,  A61K9/0014 ,  A61K47/26 ,  A61Q11/00 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/10 ,  C07H3/04 ,  C07H3/06 ,  C12N9/1051 ,  C12N9/2425 ,  C12N9/2428 ,  C12P19/04 ,  C12Y302/01001 ,  C12Y302/01002 ,  C12Y302/01003 ,  C12Y302/0102

    摘要： The object of the present invention is to provide an α-isomaltosylglucosaccharide-forming enzyme, process of the same, cyclotetrasaccharide, and saccharide composition comprising the saccharide which are obtainable by using the enzyme; and is solved by establishing an α-isomaltosylglucosaccharide-forming enzyme which forms a saccharide, having a glucose polymerization degree of at least three and having both the α-1,6 glucosidic linkage as a linkage at the non-reducing end and the α-1,4 glucosidic linkage other than the linkage at the non-reducing end, by catalyzing the α-glucosyl-transfer from a saccharide having a glucose polymerization degree of at least two and having the α-1,4 glucosidic linkage as a linkage at the non-reducing end without substantially increasing the reducing power; α-isomaltosyl-transferring method using the enzyme; method for forming α-isomaltosylglucosaccharide; process for producing a cyclotetrasaccharide having the structure of cyclo{66)-α-D-glucopyranosyl-(163)-α-D-glucopyranosyl-(166)-α-D-glucopyranosyl-(163)-α-D-glucopyranosyl-(16} using both the α-isomaltosylglucosaccharide-forming enzyme and the α-isomaltosyl-transferring enzyme; and the uses of the saccharides obtainable therewith.

    摘要翻译： 本发明的目的是提供一种α-异麦芽糖基葡萄糖形成酶，其工艺，环四糖和包含可通过使用酶获得的糖的糖组合物; 并且通过建立形成葡糖聚合度至少为3并且在非还原末端具有α-1,6糖苷键作为连接的α糖异构体糖结合酶和α - 通过催化从葡萄糖聚合度至少为2并具有α-1,4糖苷键作为连接的糖的α-葡糖基转移而在非还原性末端的连接以外的1,4-葡糖苷键 所述非还原端基本上不增加所述还原能力; 使用该酶的α-异麦芽糖基转移法; 形成α-异麦芽糖基糖的方法; 制备具有环{66）-alpha-D-吡喃葡萄糖基 - （163）-al-D-glucopyranosyl-（166）-al-D-glucopyranosyl-（163）-al-D-glucopyranosyl-（163）-al-D-glucopyranosyl- （16）同时使用α-异麦芽糖基糖产生酶和α-异麦芽糖基转移酶;以及可用其获得的糖的用途。

    Cyanine Dye
    147.
    发明申请
    Cyanine Dye 失效
    花青染料

    公开(公告)号：US20080000034A1

    公开(公告)日：2008-01-03

    申请号：US10590895

    申请日：2005-02-24

    申请人： Yasushi Aizawa ,  Yoshinori Koyama ,  Ayashi Noguchi

    发明人： Yasushi Aizawa ,  Yoshinori Koyama ,  Ayashi Noguchi

    IPC分类号： C09B69/02 ,  C09B23/00 ,  C09B45/14 ,  C09B45/20

    CPC分类号： C09B69/02 ,  C09B69/045

    摘要： An objective of this invention is to extend the range of choosing organic dye compounds as radiation-absorbing agents in a variety of fields by providing a novel organic dye compound which absorbs short-wavelength visible radiation and exhibits a superior in optical resistance, solubility in solvents, and heat characteristics required in a novel field in which the organic dye compound is applied: The objective is attainable by providing a cyanine dye which has a specific structure and exhibits a major adsorption maximum at a wavelength longer than 400 nm in a solution.

    摘要翻译： 本发明的目的是通过提供吸收短波长可见光辐射并表现出优异的耐光性，溶剂在溶剂中的溶解度的新型有机染料化合物来扩展在各种领域中选择有机染料化合物作为辐射吸收剂的范围 ，以及应用有机染料化合物的新领域中所需的热特性：通过提供具有特定结构并在溶液中在长于400nm的波长下显示主要吸收最大值的花青染料可以实现该目的。

    Pharmaceutical composition of human interferon-α2 and interferon α8 subtypes
    149.
    发明授权
    Pharmaceutical composition of human interferon-α2 and interferon α8 subtypes 失效
    人类干扰素-α2和干扰素α8亚型的药物组合物

    公开(公告)号：US07189389B2

    公开(公告)日：2007-03-13

    申请号：US10777081

    申请日：2004-02-13

    申请人： Yoshiaki Yanai ,  Osamu Sano ,  Masashi Kurimoto

    发明人： Yoshiaki Yanai ,  Osamu Sano ,  Masashi Kurimoto

    IPC分类号： A61K38/21 ,  C07K1/00

    CPC分类号： A61K38/212

    摘要： The objects of the present invention are to reveal a specific combination of human interferon-α subtypes that remarkably enhances the expression of protein synthesis inhibitory genes, and to provide an expression enhancer comprising as effective ingredients interferon-α subtypes in such a combination and uses thereof. The above objects are solved by providing an expression enhancer for protein synthesis inhibitory genes which comprises as effective ingredients interferon-α2 and interferon-α8 subtypes of human interferon-α, and uses thereof including pharmaceuticals.

    摘要翻译： 本发明的目的是揭示显着增强蛋白质合成抑制基因表达的人类干扰素-α亚型的特异性组合，并提供一种表达增强剂，其包含作为有效成分的干扰素-α亚型在这种组合中的用途及其用途 。 通过提供用于蛋白质合成抑制基因的表达增强子来解决上述目的，其包含作为干扰素-α的干扰素-α2和干扰素-α8亚型的有效成分及其包括药物的用途。