公开(公告)号：US20170254825A1

公开(公告)日：2017-09-07

申请号：US15599080

申请日：2017-05-18

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Dietmar Reisch ,  Gottlieb Schacher

IPC: C12M1/02 ,  G01N33/00

CPC classification number: G01N35/025 ,  B01L9/06 ,  B65G65/00 ,  G01N1/28 ,  G01N33/00 ,  G01N35/0099 ,  G01N35/02 ,  G01N2035/0462 ,  G01N2035/0465 ,  G01N2035/0467 ,  G01N2035/0491 ,  Y10T436/2575

Abstract: An automated system and method for processing vessels containing biological samples are presented. The system comprises vessel holders, a transport medium for transporting the vessel holders between the components of the system, a work cell for processing, a storage module for empty vessel holders, wherein the storage module is connected to the transport medium, a robotic manipulator for engaging and/or disengaging the vessels with empty vessel holders, an empty vessel holder transfer unit for introducing empty vessel holders into or retrieving them from the storage module, and an empty vessel holder detection unit, including an empty vessel holder detector for discriminating between filled and empty vessel holders as well as a transfer initiator configured to initiate the introduction or re-introduction of an empty vessel holder detected in or on the transport medium into the storage module by the empty vessel holder transfer unit.

公开(公告)号：US20170253431A1

公开(公告)日：2017-09-07

申请号：US15437942

申请日：2017-02-21

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Rolf Schnarwiler ,  Beat Jaeggi

IPC: B65G11/08

CPC classification number: B65G11/086 ,  G01N35/04 ,  G01N2035/0406 ,  G01N2035/046 ,  G01N2035/0467

Abstract: A transporting device for transporting a laboratory diagnostic vessel carrier from a first line portion to a second line portion of a conveying line is disclosed. The first line portion is above the second line portion with respect to gravity. The transporting device comprises first and second transporting portions. The first transporting portion is connected to the first line portion and the second transporting portion is connected to the second line portion. The first transporting portion extends in a first direction and the second transporting portion extends in a second direction different from the first direction. The first and second transporting portions transport the laboratory diagnostic vessel carrier by gravity. The first direction comprises at least a first component and the second direction comprises at least a second component. The second component is opposite to the first component. Further, a conveying line comprising such a transporting device is disclosed.

公开(公告)号：US09751208B2

公开(公告)日：2017-09-05

申请号：US15040383

申请日：2016-02-10

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Matthias Edelmann

IPC: B25J9/04 ,  B65G47/90 ,  B25J9/00 ,  B25J9/10

CPC classification number: B25J9/044 ,  B25J9/0021 ,  B25J9/042 ,  B25J9/1065 ,  B65G47/902 ,  B65G47/905

Abstract: A robotic device is presented. The robotic device comprises a stationary base, a first arm rotationally mounted on the base for rotation about a first axis (I), a second arm rotationally mounted on the first arm for rotation about a second axis (II), in which second axis (II) is parallel to the first axis (I), a first driving device for driving the first arm to rotate about the first axis (I), and a second arm drive unit with a second driving device for driving the second arm to rotate about the second axis (I). The first driving device and the second driving devices are mounted stationary at the base. A linear drive unit moves the first arm and the second arm in a direction parallel to the first axis (I) and the second axis (II). The linear drive unit comprises a third driving device mounted stationary at the base.

公开(公告)号：USD794068S1

公开(公告)日：2017-08-08

申请号：US29490200

申请日：2014-05-07

Applicant: Roche Diagnostics Operations, Inc.

Designer： Magnus Gyllensward ,  Mark G. Mears ,  Wilfried Schmidt

公开(公告)号：US09718595B2

公开(公告)日：2017-08-01

申请号：US13928088

申请日：2013-06-26

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Wilhelm Leichner

IPC: B65D81/02 ,  A61B5/151 ,  A61B5/157 ,  A61B5/15

CPC classification number: B65D81/025 ,  A61B5/150022 ,  A61B5/15029 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/15146 ,  A61B5/15151 ,  A61B5/15161 ,  A61B5/15176 ,  A61B5/157

Abstract: A container at least to some extent composed of a sheet of composite material, where the composite material includes an aluminum foil with a first and a second surface side, a first polymer layer, bonded to at least one of the two surface sides, where the aluminum foil covers, by way of the polymer layer, at least one aperture of a holder, where the composite material and the holder together form the container, where the holder accepts at least one analytical aid in a cutout, where the aluminum foil has been molded.

公开(公告)号：US20170184622A1

公开(公告)日：2017-06-29

申请号：US15455773

申请日：2017-03-10

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Achim Sinz ,  Christian Riether ,  Norbert Oranth ,  Martin Burri

IPC: G01N35/04 ,  B65G54/02 ,  G01N35/00

Abstract: A method of operating a laboratory sample distribution system is presented. The method comprises a number of sample container carriers on a transport plane by a number of electro-magnetic actuators. The method is adapted to compensate deviations regarding physical properties of the sample container carriers, the transport plane and the electro-magnetic actuators compared to reference components. A laboratory automation system comprising such a laboratory sample distribution system is also presented.

公开(公告)号：US20170184591A1

公开(公告)日：2017-06-29

申请号：US15246607

申请日：2016-08-25

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Elke Faatz ,  Christian Scholz ,  Peter Muench

IPC: G01N33/569 ,  C07K14/005

CPC classification number: G01N33/56988 ,  C07K14/005 ,  C07K2319/35 ,  C12N2740/14022 ,  C12N2740/14031 ,  C12N2740/14051 ,  G01N33/56983 ,  G01N2333/15 ,  G01N2469/20

Abstract: The invention concerns soluble and antigenic HTLV p24 variants that can be fused to chaperones and their use in diagnostic applications such as immunoassays for detecting antibodies against HTLV-I or HTLV-II in an isolated biological sample. In particular, the invention relates to a soluble HTLV-I or HTLV-II p24 antigen comprising either the N- or the C-terminal domain of p24 and lacking the other domain. Moreover, the invention covers recombinant DNA molecules encoding these HTLV-I and -II fusion antigens as well as their recombinant production using expression vectors and host cells transformed with such expression vectors. In addition, the invention focuses on compositions of these HTLV p24 antigens with HTLV gp21 antigen and on an immunoassay method for detection of HTLV antibodies using the antigens of the invention. Also the use of HTLV p24 antigens in an in vitro diagnostic assay as well as a reagent kit for detection of anti-HTLV-antibodies comprising said HTLV antigens is encompassed.

公开(公告)号：US20170176306A1

公开(公告)日：2017-06-22

申请号：US15387007

申请日：2016-12-21

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Christoph Boehm ,  Thorsten Brueckner ,  Sascha Lutz ,  Bruntje Esrom ,  Herbel Michael

IPC: G01N1/40 ,  B01L3/00

CPC classification number: G01N1/4077 ,  A61B5/1411 ,  A61B5/150022 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150343 ,  A61B5/150358 ,  A61B5/150755 ,  A61B5/150832 ,  A61B5/157 ,  A61B10/0045 ,  B01D17/0217 ,  B01L3/5021 ,  B01L3/502753 ,  B01L2200/025 ,  B01L2200/026 ,  B01L2200/0631 ,  B01L2200/10 ,  B01L2300/043 ,  B01L2300/0803 ,  B01L2300/123 ,  B01L2400/0406 ,  B01L2400/0409 ,  G01N21/07 ,  G01N21/84 ,  G01N33/491 ,  G01N2001/4083 ,  Y10T436/25375 ,  Y10T436/2575

Abstract: System and method of determining an amount of an analyte in a blood sample using a cartridge and blood collector are disclosed. The blood collector has a mounting surface, a capillary structure with a curved portion, and a capillary inlet. The cartridge has a receiving surface, a cartridge inlet, a microfluidic structure, and a measurement structure. The method includes placing the blood sample into the capillary inlet; attaching the mounting surface to the receiving surface; rotating the cartridge about a rotational axis to transport the blood sample from the capillary structure to the cartridge inlet and into the microfluidic structure; controlling the rotation of the cartridge to process the blood sample into the processed sample using the microfluidic structure; controlling the rotation of the cartridge to transfer the processed sample to the measurement structure; and measuring the amount of the analyte using the measurement structure and a measurement system.

公开(公告)号：US09684007B2

公开(公告)日：2017-06-20

申请号：US14567531

申请日：2014-12-11

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Dietmar Reisch ,  Gottlieb Schacher

IPC: B65G65/00 ,  G01N35/00 ,  G01N35/02 ,  G01N1/28 ,  G01N33/00 ,  B01L9/06 ,  G01N35/04

CPC classification number: G01N35/025 ,  B01L9/06 ,  B65G65/00 ,  G01N1/28 ,  G01N33/00 ,  G01N35/0099 ,  G01N35/02 ,  G01N2035/0462 ,  G01N2035/0465 ,  G01N2035/0467 ,  G01N2035/0491 ,  Y10T436/2575

Abstract: An automated system and method for processing vessels containing biological samples are presented. The system comprises vessel holders, a transport medium for transporting the vessel holders between the components of the system, a work cell for processing, a storage module for empty vessel holders, wherein the storage module is connected to the transport medium, a robotic manipulator for engaging and/or disengaging the vessels with empty vessel holders, an empty vessel holder transfer unit for introducing empty vessel holders into or retrieving them from the storage module, and an empty vessel holder detection unit, including an empty vessel holder detector for discriminating between filled and empty vessel holders as well as a transfer initiator configured to initiate the introduction or re-introduction of an empty vessel holder detected in or on the transport medium into the storage module by the empty vessel holder transfer unit.

公开(公告)号：US09678093B2

公开(公告)日：2017-06-13

申请号：US14909782

申请日：2014-06-27

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION ,  ROCHE DIAGNOSTICS OPERATIONS, INC.

Inventor： Susumu Sakairi ,  Katsuhiro Kambara ,  Stephan Sattler ,  Reinhold Kraemer

IPC: G01N35/10 ,  G01N35/00 ,  G01N35/02 ,  B01L3/00 ,  G01N35/04

CPC classification number: G01N35/1002 ,  B01L3/50825 ,  G01N35/00663 ,  G01N35/025 ,  G01N2035/00287 ,  G01N2035/00673 ,  G01N2035/0405 ,  G01N2035/0443

Abstract: An automatic analyzer provided with a roller and a reagent container shoulder presser at the position where an operator inserts a reagent container into the automatic analyzer. The reagent container is pushed while the lid of the reagent container is made to touch the upper side of the roller and the shoulder presser is made to touch the shoulder of the reagent container, and the application of upward force to the lid causes the lid of the reagent container to be half open, after which the reagent container is inserted in the analyzer.