公开(公告)号：US20080128278A1

公开(公告)日：2008-06-05

申请号：US11682910

申请日：2007-03-07

Applicant: Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jin-a Yoo ,  Ji-su Kim ,  Jeong-yun Yang

Inventor： Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jin-a Yoo ,  Ji-su Kim ,  Jeong-yun Yang

IPC: G01N27/327

CPC classification number: C12Q1/001 ,  G01N27/3272

Abstract: A biosensor measuring an analyte contained in a sample is disclosed, including: a lower insulating substrate having formed thereon a working electrode and a reference electrode connected to lead terminals through leads, and an enzyme reactant layer formed on the electrodes to react with the analyte contained in the sample; a spacer which is interposed between the lower substrate and an upper substrate, is attached to the lower and upper substrates, and has a sample guide area to guide the sample to reach to the electrodes through the enzyme reactant layer; and an upper insulating substrate which faces the lower substrate through the spacer, where a dummy electrode is formed on the lower substrate, the dummy electrode being separated from the working electrode and the reference electrode, fixing the enzyme reactant layer, and being not connected to the leads.

Abstract translation: 公开了一种测量样品中包含的分析物的生物传感器，包括：下部绝缘基板，其上形成有工作电极和通过引线连接到引线端子的参考电极，以及形成在电极上以与所包含的分析物反应的酶反应物层 在样品中 插入在下基板和上基板之间的间隔件附接到下基板和上基板，并且具有引导样品以通过酶反应物层到达电极的样本引导区域; 以及通过间隔件面向下基板的上绝缘基板，其中在下基板上形成虚拟电极，所述虚拟电极与工作电极和参比电极分离，固定酶反应物层，并且不连接到 线索。

公开(公告)号：US20080110768A1

公开(公告)日：2008-05-15

申请号：US11654284

申请日：2007-01-17

Applicant: Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jin-a Yoo ,  Ji-su Kim ,  Jeong-yun Yang

Inventor： Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jin-a Yoo ,  Ji-su Kim ,  Jeong-yun Yang

IPC: C12M1/34

CPC classification number: C12Q1/001 ,  G01N27/3272

Abstract: A biosensor measuring an analyte contained in a sample includes a lower insulating substrate having at least one electrode and an enzyme reactant layer which is formed on the electrode to react with the analyte; a spacer which is attached to the lower substrate and an upper substrate and is provided to form a sample injection area to guide the sample to the electrode through the enzyme reactant layer; and an upper insulating substrate which faces the lower substrate and has an air discharge area to discharge air which is absorbed together with the sample through the sample injection area, where the air discharge area is formed on a layer different from that of the sample injection area.

Abstract translation: 测量样品中包含的分析物的生物传感器包括具有至少一个电极的下绝缘基底和形成在电极上以与分析物反应的酶反应物层; 附接到下基板和上基板的间隔件，并且被提供以形成样品注入区域，以通过酶反应物层将样品引导到电极; 以及面向下基板并具有空气排出区域的上绝缘基板，其通过样品注入区域与样品一起吸收的空气排出，其中空气排出区域形成在与样品注入区域不同的层上 。

公开(公告)号：US20080087543A1

公开(公告)日：2008-04-17

申请号：US11548457

申请日：2006-10-11

Applicant: Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jina Yoo ,  Min-sun Kim ,  Jae-hyun Yoo ,  Ki-won Lee

Inventor： Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jina Yoo ,  Min-sun Kim ,  Jae-hyun Yoo ,  Ki-won Lee

IPC: G01N27/26 ,  C12Q1/00

CPC classification number: C12Q1/001 ,  G01N2333/902 ,  G01N2333/904 ,  G01N2333/91 ,  G01N2333/914

Abstract: A biosensor measuring an analyte contained in a sample is provided, including: an insulative lower substrate that has at least one electrode on which an enzyme reaction layer reacting with the analyte is formed; an upper substrate that faces the lower substrate and is made of a conductive material; and an adhesive layer that has a sample feed with a predetermined height on the enzyme reaction layer and attaches the upper and lower substrates to each other, where an end of the upper substrate acts as an electrode in which an electron-transfer mediator contained in the enzyme reaction layer is oxidized or reduced, and the other end acts as an electrical contact part that electrically contacts a measurement unit.

Abstract translation: 提供了一种测量样品中包含的分析物的生物传感器，包括：具有至少一个电极的绝缘下基板，其上形成有与分析物反应的酶反应层; 面向下基板并由导电材料制成的上基板; 以及粘合剂层，其具有在酶反应层上具有预定高度的样品进料并且将上基板和下基板彼此连接，其中上基板的端部用作其中包含在电子转移介体中的电极 酶反应层被氧化或还原，另一端作为电接触测量单元的电接触部分。

公开(公告)号：US09307937B2

公开(公告)日：2016-04-12

申请号：US12722110

申请日：2010-03-11

Applicant: Byeong-Woo Bae ,  Sung-Dong Lee ,  Byung-Hoon Kho ,  Ji-Eon Ryu ,  Jin-Kyeong Kim ,  Hyou-Arm Joung ,  Yooh-Hee Lee

Inventor： Byeong-Woo Bae ,  Sung-Dong Lee ,  Byung-Hoon Kho ,  Ji-Eon Ryu ,  Jin-Kyeong Kim ,  Hyou-Arm Joung ,  Yooh-Hee Lee

IPC: G01N33/50 ,  A61B5/145 ,  G06F19/00 ,  A61B5/1455 ,  G01N33/487 ,  G06G7/58

CPC classification number: A61B5/14546 ,  A61B5/1455 ,  G01N33/48785 ,  G06F19/00 ,  G06F19/30 ,  G06F19/34 ,  G16H40/63

Abstract: Disclosed herein is a method and apparatus for measuring biomedical data. The method of measuring biomedical data using a biochemical reaction includes determining reaction termination time at which the biochemical reaction has been stabilized based on an average variation in a predetermined period in an early stage of measurement, and obtaining a final measured value by adding a correction value to a value measured at the determined reaction termination time.

Abstract translation: 本文公开了一种用于测量生物医学数据的方法和装置。 使用生物化学反应测定生物医学数据的方法包括：根据测定初期的规定期间的平均变化量，确定生物化学反应已稳定的反应终止时间，通过加入校正值得到最终测定值 到在确定的反应终止时间测量的值。

公开(公告)号：US08883086B2

公开(公告)日：2014-11-11

申请号：US12722252

申请日：2010-03-11

Applicant: Byeong-Woo Bae ,  Sung-Dong Lee ,  Byung-Hoon Kho ,  Ji-Eon Ryu ,  Jin-Kyeong Kim ,  Hyou-Arm Joung

Inventor： Byeong-Woo Bae ,  Sung-Dong Lee ,  Byung-Hoon Kho ,  Ji-Eon Ryu ,  Jin-Kyeong Kim ,  Hyou-Arm Joung

IPC: G01N33/52 ,  A61B5/145 ,  G01N21/00 ,  G01N21/17 ,  G01N33/92 ,  G01N33/487 ,  G01N33/49 ,  G01N21/84 ,  A61B5/1455

CPC classification number: A61B5/14546 ,  A61B5/145 ,  A61B5/14532 ,  A61B5/1455 ,  A61B2560/0431 ,  A61B2560/0462 ,  A61B2562/0295 ,  A61B2562/063 ,  B01L2200/025 ,  B01L2300/021 ,  B01L2300/024 ,  B01L2300/025 ,  B01L2300/0816 ,  B01L2300/0825 ,  G01N21/00 ,  G01N21/17 ,  G01N21/8483 ,  G01N33/48771 ,  G01N33/49 ,  G01N33/92 ,  Y10S435/805 ,  Y10S435/808 ,  Y10S435/97

Abstract: Disclosed herein are an apparatus and method for measuring biomedical data and a measurement strip. The apparatus includes a plurality of detection units arranged within a strip reception area on a plane and spaced apart from each other, a measurement type determination unit for determining whether reactive portions are present in areas of the measurement strip corresponding to the plurality of detection units based on detection results obtained by the detection units and determining a type of measurement based on results of the determination, a biomedical data measurement unit for activating part or all of the detection units according to the type of measurement determined by the measurement type determination unit, and measuring the biomedical data using the activated detection units, and an output unit for outputting the measured biomedical data to an outside.

Abstract translation: 本文公开了一种用于测量生物医学数据和测量条的装置和方法。 该装置包括多个检测单元，布置在平面上的条带接收区域中并彼此间隔开;测量类型确定单元，用于确定反应部分是否存在于与多个检测单元相对应的测量条带的区域中 根据由检测单元获得的检测结果，并且基于确定结果确定测量类型;生物医学数据测量单元，用于根据由测量类型确定单元确定的测量类型激活部分或全部检测单元;以及 使用激活的检测单元测量生物医学数据，以及用于将测量的生物医学数据输出到外部的输出单元。

公开(公告)号：US07947222B2

公开(公告)日：2011-05-24

申请号：US11504505

申请日：2006-08-15

Applicant: Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jina Yoo ,  Ki-won Lee

Inventor： Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jina Yoo ,  Ki-won Lee

IPC: C12Q1/68 ,  G01N27/327 ,  H04M1/38 ,  G08B1/08

CPC classification number: A61B5/6898 ,  A61B5/14532 ,  G01N27/3274 ,  H04M1/21 ,  H04M2250/12

Abstract: Disclosed is a mobile communication terminal equipped with temperature compensation function for use in bio-information measurement, including a biosensor insertion in which a biosensor directly detecting bio-information of a subject is inserted, a temperature measurement unit measuring temperatures, and a controller analyzing the bio-information inputted from the biosensor based on stored analysis data and correcting the bio-information using the temperature measured by the temperature measurement unit, in which the temperature measurement unit measures temperature of a target object without contacting the target object directly.

Abstract translation: 公开了一种配备有用于生物信息测量的温度补偿功能的移动通信终端，包括其中插入直接检测被摄体的生物信息的生物传感器的生物传感器插入，测量温度的温度测量单元和分析 基于存储的分析数据从生物传感器输入的生物信息，并且使用由温度测量单元测量的温度校正生物信息，其中温度测量单元直接测量目标对象的温度，而不直接接触目标对象。

公开(公告)号：US20100259394A1

公开(公告)日：2010-10-14

申请号：US11504505

申请日：2006-08-15

Applicant: Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jina Yoo ,  Ki-won Lee

Inventor： Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jina Yoo ,  Ki-won Lee

IPC: G05B23/02

CPC classification number: A61B5/6898 ,  A61B5/14532 ,  G01N27/3274 ,  H04M1/21 ,  H04M2250/12

Abstract: Disclosed is a mobile communication terminal equipped with temperature compensation function for use in bio-information measurement, including a biosensor insertion in which a biosensor directly detecting bio-information of a subject is inserted, a temperature measurement unit measuring temperatures, and a controller analyzing the bio-information inputted from the biosensor based on stored analysis data and correcting the bio-information using the temperature measured by the temperature measurement unit, in which the temperature measurement unit measures temperature of a target object without contacting the target object directly.

Abstract translation: 公开了一种配备有用于生物信息测量的温度补偿功能的移动通信终端，包括其中插入直接检测被摄体的生物信息的生物传感器的生物传感器插入，测量温度的温度测量单元和分析 基于存储的分析数据从生物传感器输入的生物信息，并且使用由温度测量单元测量的温度校正生物信息，其中温度测量单元直接测量目标对象的温度，而不直接接触目标对象。

公开(公告)号：US06554982B1

公开(公告)日：2003-04-29

申请号：US09889032

申请日：2001-07-12

Applicant: Jae Ho Shin ,  Sung Dong Lee ,  Hakhyun Nam ,  Geun Sig Cha ,  Byeong Woo Bae

Inventor： Jae Ho Shin ,  Sung Dong Lee ,  Hakhyun Nam ,  Geun Sig Cha ,  Byeong Woo Bae

IPC: G01N27401

CPC classification number: G01N27/301

Abstract: The present invention relates to a reference electrode for a potentiometric electrode system, characterized in that the junction in contact with a sample solution is enlarged and an ion-sensitive membrane containing an ion selective material as a protective membrane for the inner reference solution is employed, which comprises a substrate; a metal layer; an insoluble metal salt layer; an insulating film for insulating the metal layer from an aqueous solution; a hydrogel serving as an inner reference solution; the junction on the hydrogel contacting with a sample solution; the ion-sensitive, protective membrane formed over all surface areas of the hydrogel, except for the junction, to separate the sample solution from the inner reference solution or act as an ion-sensing membrane upon the contamination of the junction, whereby the operational abnormality caused by junction contamination may be easily checked and fast activation may be achieved.

Abstract translation: 本发明涉及一种用于电位电极系统的参考电极，其特征在于，与样品溶液接触的接合点被扩大，并且使用含有作为内部参比溶液的保护膜的离子选择性材料的离子敏感膜， 其包括基底; 金属层; 不溶性金属盐层; 用于将金属层与水溶液绝缘的绝缘膜; 作为内参照溶液的水凝胶; 水凝胶上的接头与样品溶液接触; 在水凝胶的所有表面区域之外形成的离子敏感的保护膜除了接合部分之外，以将样品溶液与内部参考溶液分离，或者当接合部被污染时用作离子感测膜，由此操作异常 可以容易地检查结点污染引起的并且可以实现快速激活。

公开(公告)号：US09044756B2

公开(公告)日：2015-06-02

申请号：US13588025

申请日：2012-08-17

Applicant: Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jina Yoo ,  Ki-won Lee ,  Jong-won Hong ,  Duck-sung Nam

Inventor： Byeong-woo Bae ,  Sung-dong Lee ,  Hong-seong Suk ,  Jina Yoo ,  Ki-won Lee ,  Jong-won Hong ,  Duck-sung Nam

IPC: B01L3/00 ,  G01N33/487 ,  G01N35/00

CPC classification number: G01N27/3274 ,  B01L3/545 ,  G01N33/48771 ,  G01N2035/00772

Abstract: An apparatus for reading identification information of a biosensor is provided, including a biosensor sensing unit detecting the biosensor, a light-emitting unit emitting light on an identification information recording unit when the biosensor sensing unit detects the biosensor, the identification information recording unit having the identification information of the biosensor recorded thereon, a light-receiving unit that receives the light emitted from the light-emitting unit, and reflected or refracted by or passing through the identification information recording section, and an identification information reading unit analyzing the light received by the light-receiving unit and reading the identification information of the biosensor.

Abstract translation: 提供一种用于读取生物传感器的识别信息的装置，包括检测生物传感器的生物传感器感测单元，当生物传感器感测单元检测到生物传感器时在识别信息记录单元上发光的发光单元，具有 记录在其上的生物传感器的识别信息，接收从发光单元发射并被识别信息记录部分反射或折射或通过的光的光接收单元，以及识别信息读取单元， 光接收单元并读取生物传感器的识别信息。

公开(公告)号：US08846380B2

公开(公告)日：2014-09-30

申请号：US12025443

申请日：2008-02-04

Applicant: Byeong-woo Bae ,  Sung-dong Lee ,  Min-sun Kim ,  Jae-hyun Yoo ,  Hyoung-soo Kim ,  Ki-won Lee ,  Ju-pyo Hong

Inventor： Byeong-woo Bae ,  Sung-dong Lee ,  Min-sun Kim ,  Jae-hyun Yoo ,  Hyoung-soo Kim ,  Ki-won Lee ,  Ju-pyo Hong

IPC: C12M1/34 ,  G01N33/72 ,  G01N33/543 ,  B01L3/00

CPC classification number: G01N33/723 ,  B01L3/502 ,  B01L2200/0621 ,  B01L2400/0457 ,  G01N33/54306 ,  G01N33/726

Abstract: A reaction cassette for a glycated hemoglobin meter and a measuring method thereof are provided. The reaction cassette for the glycated hemoglobin meter includes: a first zone receiving a first reagent and a blood sample; a second zone receiving a second reagent; a reaction zone in which the blood sample reacts with the first reagent, or through which the second reagent passes to react with a first blood sample mixture obtained by reacting the blood sample with the first reagent; and a measurement zone measuring an amount of total hemoglobin in the first blood sample mixture, or measuring an amount of glycated hemoglobin in a second blood sample mixture obtained by reacting the first blood sample mixture with the second reagent, wherein the blood sample, the first reagent, and the second reagent move between the reaction zone and the measurement zone according to a rotation angle of the reaction cassette when the reaction cassette is rotated. Therefore, since the reaction cassette rotates automatically, it is possible to measure the amount of glycated hemoglobin in a blood sample through simple manipulation and reduce a manufacturing time. Furthermore, since reagents are supplied to the reaction cassette from a separate reagent pack, it is possible to resolve storage and distribution problems of the reaction cassette, which occur when reagents are stored in the reaction cassette.

Abstract translation: 提供了糖化血红蛋白计的反应盒及其测定方法。 糖化血红蛋白计的反应盒包括：接收第一试剂和血液样品的第一区; 接收第二试剂的第二区域; 血液样品与第一试剂反应的反应区域，或第二试剂通过的反应区域与通过使血液样品与第一试剂反应获得的第一血液样品混合物反应; 以及测量第一血液样品混合物中的总血红蛋白量的测量区域，或者测量通过使第一血液样品混合物与第二试剂反应获得的第二血液样品混合物中的糖化血红蛋白的量，其中，血液样品，第一 试剂，第二试剂在反应盒旋转时根据反应盒的旋转角度在反应区和测量区之间移动。 因此，由于反应盒自动旋转，因此可以通过简单的操作来测量血液样品中的糖化血红蛋白的量，并减少制造时间。 此外，由于将试剂从单独的试剂盒供给到反应盒中，因此可以解决当试剂储存在反应盒中时发生的反应盒的储存和分配问题。