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28 条记录 (耗时 0.057 秒)

    Methods and apparatus for accessing and stabilizing an area of the heart
    12.
    发明申请
    Methods and apparatus for accessing and stabilizing an area of the heart 审中-公开
    获取和稳定心脏区域的方法和装置

    公开(公告)号：US20050261673A1

    公开(公告)日：2005-11-24

    申请号：US11172287

    申请日：2005-06-30

    申请人： Matthew Bonner ,  Raymond Usher ,  Victor Chen ,  James Keogh

    发明人： Matthew Bonner ,  Raymond Usher ,  Victor Chen ,  James Keogh

    IPC分类号： A61B18/14 ,  A61B19/00 ,  A61B19/02 ,  A61B19/08 ,  A61B19/10 ,  A61M1/00 ,  A61B18/18

    CPC分类号： A61B18/1485 ,  A61B17/0401 ,  A61B18/1402 ,  A61B46/00 ,  A61B46/23 ,  A61B50/20 ,  A61B2017/00026 ,  A61B2017/00039 ,  A61B2017/00084 ,  A61B2017/0243 ,  A61B2017/06052 ,  A61B2017/306 ,  A61B2018/00291 ,  A61B2090/306 ,  A61B2090/3614 ,  A61B2218/007 ,  A61M1/008

    摘要： A tubular suction tool for accessing an anatomic surface or anatomic space and particularly the pericardium to access pericardial space and the epicardial surface of the heart to implant cardiac leads in a minimally invasive manner are disclosed. The suction tool incorporates a suction pad concave wall defining a suction cavity, a plurality of suction ports arrayed about the concave wall, and a suction lumen, to form a bleb of tissue into the suction cavity when suction is applied. The suction cavity extends along one side of the suction pad, so that the suction pad and suction cavity can be applied tangentially against a tissue site. The suction tool can incorporate light emission and video imaging of tissue adjacent the suction pad. A working lumen terminating in a working lumen port into the suction cavity enables introduction of tools, cardiac leads, and other instruments, cells, drugs or materials into or through the tissue bleb drawn into the suction cavity.

    摘要翻译： 公开了一种用于进入解剖表面或解剖空间的管状抽吸工具，特别是用于进入心包的心包以心脏心外膜表面以微创方式植入心脏引线。 抽吸工具包括限定吸入腔的吸盘凹壁，围绕凹壁排列的多个吸入口和吸入腔，以在施加抽吸时形成吸入腔中的组织泡。 吸入腔沿吸盘的一侧延伸，使得吸力垫和抽吸腔可以相对于组织部位切向施加。 吸入工具可以包含邻近吸盘的组织的发光和视频成像。 终止在吸入腔中的工作管腔端口的工作腔使得可以将工具，心脏引线以及其它器械，细胞，药物或材料引入到吸入腔中或穿过组织气泡中的吸入腔中。

    Devices and methods for interstitial injection of biologic agents into tissue
    13.
    发明申请
    Devices and methods for interstitial injection of biologic agents into tissue 有权
    将生物制剂间插注入组织的装置和方法

    公开(公告)号：US20070049863A1

    公开(公告)日：2007-03-01

    申请号：US11545197

    申请日：2006-10-10

    申请人： Scott Jahns ,  Gary Oehme ,  Matthew Bonner ,  James Keogh

    发明人： Scott Jahns ,  Gary Oehme ,  Matthew Bonner ,  James Keogh

    IPC分类号： A61M31/00

    CPC分类号： A61B17/3478 ,  A61B17/00234 ,  A61B17/205 ,  A61B2017/00247 ,  A61B2017/00876 ,  A61B2017/2936 ,  A61B2017/2943 ,  A61B2017/306 ,  A61B2018/00392 ,  A61B2090/034 ,  A61M5/32 ,  A61M2025/0086 ,  A61M2025/0087

    摘要： Apparatus and methods for injecting biological agents into tissue. Devices are provided having elongate shafts and distal injection heads for transversely driving needles into tissue and injecting medical agents into the tissue through the needles. A longitudinal force directed along the shaft can be translated to a needle driving force transverse to the shaft. Some devices provide controllably variable needle penetration depth. Devices include mechanical needle drivers utilizing four link pantographs, rack and pinions, and drive yokes for driving a first needle bearing body toward a second tissue contacting body. Other devices include inflatable members for driving and retracting needles. Still other devices include magnets for biasing the needles in extended and/or retracted positions. The invention includes minimally invasive methods for epicardially injecting cardiocyte precursor cells into infarct myocardial tissue.

    摘要翻译： 将生物制剂注入组织的装置和方法。 设备具有细长的轴和远端注射头，用于将针横向驱动到组织中，并通过针将药剂注射到组织中。 沿着轴引导的纵向力可以平移到与轴垂直的针驱动力​​。 一些装置提供可控的可变针穿透深度。 设备包括利用四个连杆缩放仪，齿条和小齿轮的机械针驱动器和用于将第一滚针轴承体朝向第二组织接触体驱动的驱动轭。 其他装置包括用于驱动和缩回针的可充气构件。 还有其它装置包括用于在延伸和/或缩回位置偏置针的磁体。 本发明包括用心外膜将心脏细胞前体细胞注入梗死心肌组织的微创方法。

    Method and system for nerve stimulation and cardiac sensing prior to and during a medical procedure
    14.
    发明申请
    Method and system for nerve stimulation and cardiac sensing prior to and during a medical procedure 审中-公开
    在医疗过程之前和期间神经刺激和心脏感知的方法和系统

    公开(公告)号：US20070208388A1

    公开(公告)日：2007-09-06

    申请号：US11796663

    申请日：2007-04-27

    申请人： Scott Jahns ,  Michael Hill ,  James Keogh

    发明人： Scott Jahns ,  Michael Hill ,  James Keogh

    IPC分类号： A61N1/362

    CPC分类号： A61N1/36114 ,  A61N1/362 ,  A61N1/385

    摘要： A method of performing a medical procedure, such as surgery, is provided. A nerve is stimulated in order to adjust the beating of the heart to a first condition, such as a stopped or slowed condition. The medical procedure is performed on the heart or another organ. The stimulation of the nerve is stopped in order to adjust the beating of the heart to a second condition, such as a beating condition. The heart itself may also be stimulated to a beating condition, such as by pacing. The stimulation of the nerve may be continued in order to allow the medical procedure to be continued. A sensor to sense a characteristic of a fluid or tissue, such as an impending contraction, may be also used during the medical procedure. Systems and devices for performing the medical procedure are also provided.

    摘要翻译： 提供了一种执行诸如手术的医疗程序的方法。 刺激神经以将心脏的跳动调节到第一状态，例如停止或减缓的状态。 医疗程序在心脏或另一个器官上进行。 停止对神经的刺激，以便将心脏的跳动调节到第二状态，例如打浆状态。 心脏本身也可能被刺激到跳动状态，例如通过起搏。 可以继续刺激神经以允许继续医疗手术。 也可以在医疗过程中使用用于感测流体或组织的特征的传感器，例如即将收缩的收缩。 还提供用于执行医疗程序的系统和设备。

    Method and system for monitoring and controlling systemic and pulmonary circulation during a medical procedure
    15.
    发明申请
    Method and system for monitoring and controlling systemic and pulmonary circulation during a medical procedure 审中-公开
    在医疗过程中监测和控制全身和肺循环的方法和系统

    公开(公告)号：US20050096707A1

    公开(公告)日：2005-05-05

    申请号：US11000262

    申请日：2004-11-30

    申请人： Michael Hill ,  Scott Jahns ,  James Keogh

    发明人： Michael Hill ,  Scott Jahns ,  James Keogh

    IPC分类号： A61N1/36 ,  A61N1/38 ,  A61N1/365

    CPC分类号： A61N1/36114 ,  A61N1/385

    摘要： A method of performing a medical procedure, such as surgery, is provided. The system comprises a sensor to sense a biological characteristic, such as a chemical, physical or physiological characteristic of a bodily tissue or fluid. The method also comprises a nerve stimulator in communication with the sensor to inhibit beating of a heart when the sensor senses the biological characteristic at a first value; and a cardiac stimulator in communication with the sensor to stimulate beating of the heart when the sensor senses the biological characteristic at a second value.

    摘要翻译： 提供了一种执行诸如手术的医疗程序的方法。 该系统包括用于感测身体组织或液体的生物学特性，例如化学，物理或生理特征的传感器。 所述方法还包括与所述传感器通信的神经刺激器，以在所述传感器以第一值感测所述生物学特性时抑制心脏跳动; 以及与所述传感器通信的心脏刺激器，以在所述传感器以第二值感测所述生物特征时刺激所述心跳。

    Methods and systems for treating injured cardiac tissue
    18.
    发明申请
    Methods and systems for treating injured cardiac tissue 审中-公开
    治疗受伤心脏组织的方法和系统

    公开(公告)号：US20070093748A1

    公开(公告)日：2007-04-26

    申请号：US11643359

    申请日：2006-12-20

    申请人： Asha Nayak ,  James Keogh

    发明人： Asha Nayak ,  James Keogh

    IPC分类号： A61M31/00 ,  A61M37/00

    CPC分类号： A61B17/3478 ,  A61B2017/00247 ,  A61B2017/00495 ,  A61B2017/0243 ,  A61B2017/306 ,  A61B2017/308 ,  A61B2018/00392 ,  A61N1/306 ,  A61N1/325 ,  A61N1/36014

    摘要： Methods and systems are disclosed for treating injury to cardiac tissue by delivering a composition which provides structural support to the cardiac tissue. The composition helps to prevent chamber remodeling by providing structural reinforcement of the tissue or structural reinforcement of the tissue combined with biological therapy. The structurally reinforcing composition can thicken the wall of a heart, or act to prevent further thinning and thereby provide resistance against further remodeling. A number of compositions are disclosed, including multi-component substances such as autologous platelet gel, and other substances. The compositions disclosed can contain additives to augment/enhance the desired effects of the injection.

    摘要翻译： 公开了通过递送向心脏组织提供结构支持的组合物来治疗心脏组织损伤的方法和系统。 该组合物通过提供结合组织或组织结构加强组织结合生物疗法来防止室重塑。 结构上增强的组合物可以增厚心脏的壁，或用于防止进一步变薄，从而提供抵抗进一步重塑的抵抗力。 公开了许多组合物，包括多组分物质如自体血小板凝胶和其它物质。 所公开的组合物可以含有添加剂以增强/增强注射的期望效果。