公开(公告)号：US20150282743A1

公开(公告)日：2015-10-08

申请号：US14742202

申请日：2015-06-17

Applicant: Google Inc.

Inventor： James Etzkorn ,  Zenghe Liu

IPC: A61B5/1486 ,  A61B5/145 ,  A61B5/00 ,  G01N27/30 ,  G01N27/416

CPC classification number: A61B5/1486 ,  A61B3/101 ,  A61B5/0002 ,  A61B5/0004 ,  A61B5/002 ,  A61B5/14507 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1477 ,  A61B5/6821 ,  A61B5/7264 ,  A61B2560/0214 ,  G01N27/30 ,  G01N27/3271 ,  G01N27/4166 ,  G02C7/04

Abstract: An eye-mountable device includes an electrochemical sensor embedded in a polymeric material configured for mounting to a surface of an eye. The electrochemical sensor includes a working electrode, a reference electrode, and a reagent that selectively reacts with an analyte to generate a sensor measurement related to a concentration of the analyte in a fluid to which the eye-mountable device is exposed. The working electrode can have a first side edge and a second side edge. The reference electrode can be situated such that at least a portion of the first and second side edges of the working electrode are adjacent respective sections of the reference electrode.

Abstract translation: 一种可眼睛安装的装置包括嵌入聚合物材料中的电化学传感器，其被配置用于安装到眼睛的表面。 电化学传感器包括工作电极，参比电极和选择性地与分析物反应以产生与可眼睛安装的装置暴露于的流体中的分析物的浓度相关的传感器测量的试剂。 工作电极可以具有第一侧边缘和第二侧边缘。 参考电极可以被定位成使得工作电极的第一和第二侧边缘的至少一部分与参考电极的相应部分相邻。

公开(公告)号：US20150038809A1

公开(公告)日：2015-02-05

申请号：US14518986

申请日：2014-10-20

Applicant: Google Inc.

Inventor： James Etzkorn ,  Babak Amirparviz

IPC: A61B5/00 ,  A61B5/1455 ,  A61B5/145

CPC classification number: A61B5/6821 ,  A61B5/0002 ,  A61B5/0004 ,  A61B5/14507 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/14865 ,  A61B5/6867 ,  G01N27/3271 ,  G02C7/04 ,  H01L21/568 ,  H01L23/3107 ,  H01L2224/81001 ,  H01Q1/273 ,  H02J50/20 ,  H04B5/0031 ,  H04B5/0037 ,  Y10T29/49826

Abstract: An eye-mountable device includes an electrochemical sensor embedded in a polymeric material configured for mounting to a surface of an eye. The electrochemical sensor includes a working electrode and a reference electrode that reacts with an analyte to generate a sensor measurement related to a concentration of the analyte in a fluid to which the eye-mountable device is exposed. An example assembly process includes: forming a sacrificial layer on a working substrate; forming a first layer of a bio-compatible material on the sacrificial layer; providing an electronics module on the first layer of the bio-compatible material, forming a second layer of the bio-compatible material to cover the electronics module; and annealing the first and second layers of the bio-compatible material together to form an encapsulated structure having the electronics module fully encapsulated by the bio-compatible material.

Abstract translation: 一种可眼睛安装的装置包括嵌入聚合物材料中的电化学传感器，其被配置用于安装到眼睛的表面。 电化学传感器包括工作电极和与分析物反应的参比电极，以产生与可眼睛安装的装置暴露的流体中的分析物的浓度相关的传感器测量。 示例性组装过程包括：在工作衬底上形成牺牲层; 在所述牺牲层上形成生物相容性材料的第一层; 在所述生物相容材料的第一层上提供电子模块，形成所述生物相容材料的第二层以覆盖所述电子模块; 以及将所述生物相容性材料的所述第一和第二层退火在一起以形成具有由所述生物相容性材料完全包封的所述电子模块的封装结构。

公开(公告)号：US20140290054A1

公开(公告)日：2014-10-02

申请号：US13851290

申请日：2013-03-27

Applicant: Google Inc.

Inventor： James Etzkorn

IPC: H05K3/30

CPC classification number: A61B5/14546 ,  A61B3/101 ,  A61B5/0002 ,  A61B5/14532 ,  A61B5/1473 ,  A61B5/1477 ,  A61B5/6813 ,  A61B5/6821 ,  A61B2560/0214 ,  A61B2562/12 ,  B29D11/00817 ,  C12Q1/006 ,  G01N27/3272 ,  G02B1/043 ,  G02C7/04 ,  G02C7/049 ,  G02C7/083 ,  H01L2224/04105 ,  H01L2924/18162 ,  H05K1/185 ,  H05K3/32 ,  H05K2201/10098 ,  H05K2201/10151 ,  H05K2203/1469 ,  Y10T29/49018 ,  Y10T29/4913 ,  Y10T29/49146 ,  Y10T29/49155 ,  Y10T29/49158 ,  Y10T29/49163

Abstract: A mountable device includes a bio-compatible structure embedded in a polymer that defines at least one mounting surface. The bio-compatible structure includes an electronic component having electrical contacts, sensor electrodes, and electrical interconnects between the sensor electrodes and the electrical contacts. The bio-compatible structure is fabricated such that it is fully encapsulated by a bio-compatible material, except for the sensor electrodes. In the fabrication, the electronic component is positioned on a first layer of bio-compatible material and a second layer of bio-compatible material is formed over the first layer of bio-compatible material and the electronic component. The electrical contacts are exposed by removing a portion of the second layer, a conductive pattern is formed to define the sensor electrodes and electrical interconnects, and a third layer of bio-compatible material is formed over the conductive pattern. The sensor electrodes are exposed by removing a portion of the third layer.

Abstract translation: 可安装的装置包括嵌入在聚合物中的生物相容结构，其限定至少一个安装表面。 生物相容性结构包括具有电触点，传感器电极和传感器电极与电触点之间的电互连的电子部件。 生物相容结构被制造成除了传感器电极之外，其被生物相容的材料完全包封。 在制造中，电子部件被定位在生物相容材料的第一层上，并且生物相容性材料的第二层形成在第一层生物相容材料和电子部件上。 通过去除第二层的一部分来暴露电触点，形成导电图案以限定传感器电极和电互连，并且在导电图案上形成第三层生物相容性材料。 通过去除第三层的一部分来暴露传感器电极。

公开(公告)号：US20140200424A1

公开(公告)日：2014-07-17

申请号：US13741725

申请日：2013-01-15

Applicant: Google Inc.

Inventor： James Etzkorn ,  Babak Amirparviz

IPC: A61B5/00

CPC classification number: A61B5/6821 ,  A61B5/0002 ,  A61B5/0004 ,  A61B5/14507 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/1468 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/14865 ,  A61B5/6867 ,  G01N27/3271 ,  G02C7/04 ,  H01L21/568 ,  H01L23/3107 ,  H01L2224/81001 ,  Y10T29/49826

Abstract: An eye-mountable device includes an electrochemical sensor embedded in a polymeric material configured for mounting to a surface of an eye. The electrochemical sensor includes a working electrode and a reference electrode that reacts with an analyte to generate a sensor measurement related to a concentration of the analyte in a fluid to which the eye-mountable device is exposed. An example assembly process includes: forming a sacrificial layer on a working substrate; forming a first layer of a bio-compatible material on the sacrificial layer; providing an electronics module on the first layer of the bio-compatible material, forming a second layer of the bio-compatible material to cover the electronics module; and annealing the first and second layers of the bio-compatible material together to form an encapsulated structure having the electronics module fully encapsulated by the bio-compatible material.

Abstract translation: 一种可眼睛安装的装置包括嵌入聚合物材料中的电化学传感器，其被配置用于安装到眼睛的表面。 电化学传感器包括工作电极和与分析物反应的参比电极，以产生与可眼睛安装的装置暴露的流体中的分析物的浓度相关的传感器测量。 示例性组装过程包括：在工作衬底上形成牺牲层; 在所述牺牲层上形成生物相容性材料的第一层; 在所述生物相容材料的第一层上提供电子模块，形成所述生物相容材料的第二层以覆盖所述电子模块; 以及将所述生物相容性材料的所述第一和第二层退火在一起以形成具有由所述生物相容性材料完全包封的所述电子模块的封装结构。

公开(公告)号：US20160066825A1

公开(公告)日：2016-03-10

申请号：US14476916

申请日：2014-09-04

Applicant: Google Inc.

Inventor： Daniel Patrick Barrows ,  James Etzkorn

IPC: A61B5/1477 ,  B29C63/00 ,  A61B5/145

CPC classification number: A61B5/1477 ,  A61B5/14507 ,  A61B5/14532 ,  A61B5/6821 ,  A61B2562/12 ,  B29C63/0013 ,  B29K2029/00 ,  G02B1/043 ,  G02C7/00 ,  G02C7/04 ,  G02C11/10

Abstract: A body-mountable device may be formed of a polymeric material. A molding form can define a cavity and polymeric material can be formed using the mold to create a device shaped in accordance with the cavity. Electronics disposed on a substrate can be encapsulated within the polymeric material by forming a first layer of polymeric material, positioning the substrate on the first layer, and then forming a second layer of polymeric material over the substrate. A channel can expose a sensor disposed on the substrate. The channel may be formed while molding the second layer of polymeric material over the substrate. The molding form can include a protrusion that extends toward the sensor. A sacrificial sealant material can be applied to the sensor or the protrusion to create a seal between the protrusion and the sensor. The polymeric material forms around the sealed protrusion to create the channel.

Abstract translation: 身体安装装置可以由聚合物材料形成。 模制形式可以限定空腔，并且可以使用模具形成聚合材料以形成根据空腔成形的装置。 设置在基底上的电子可以通过形成聚合物材料的第一层，将基底定位在第一层上，然后在基底上形成第二层聚合材料，将其包封在聚合物材料内。 通道可以暴露设置在基板上的传感器。 可以在衬底上模制第二层聚合物材料的同时形成通道。 模制形式可以包括向传感器延伸的突起。 可以将牺牲密封剂材料施加到传感器或突起以在突起和传感器之间形成密封。 聚合物材料围绕密封突起形成以形成通道。

公开(公告)号：US20160003760A1

公开(公告)日：2016-01-07

申请号：US14325219

申请日：2014-07-07

Applicant: Google Inc.

Inventor： James Etzkorn

IPC: G01N27/30 ,  A61B5/145

CPC classification number: A61B5/14507 ,  A61B5/0537 ,  A61B5/14532 ,  A61B5/1477 ,  A61B5/6821 ,  A61B5/742 ,  A61B2560/0468 ,  A61B2562/125 ,  G02C7/04 ,  G02C11/10

Abstract: An electrochemical sensor is disposed on a sensor substrate suitable for flip-chip mounting to another substrate. The electrochemical sensor can be fabricated in bulk by patterning sets of electrodes on a common substrate with vias that electrically couple each electrode to a conductive pad on the opposite side of the substrate. The substrate with electrodes thereon can then be diced and the individual electrochemical sensors can be flip-chip mounted in a body-mountable device in which the sensor can be used to obtain analyte concentrations. As a result, fabrication of the electrochemical sensor electrodes can be isolated from fabrication of the other electronics in the device, which can facilitate efficient fabrication of the sensor and allows for other electronics to be fabricated without restrictions associated with the electrode fabrication.

Abstract translation: 电化学传感器设置在适于倒装芯片安装到另一基板的传感器基板上。 电化学传感器可以通过在具有通孔的共同衬底上图案化组的电极来大量制造，该过孔将每个电极电耦合到衬底的相对侧上的导电焊盘。 然后可以对其上具有电极的基板进行切割，并且可以将各个电化学传感器倒装安装在体内安装的装置中，其中传感器可用于获得分析物浓度。 结果，电化学传感器电极的制造可以与器件中的其它电子器件的制造隔离开来，这可以促进传感器的有效制造，并允许制造其它电子器件，而不受与电极制造相关的限制。

公开(公告)号：US20150214567A1

公开(公告)日：2015-07-30

申请号：US14163663

申请日：2014-01-24

Applicant: Google Inc.

Inventor： James Etzkorn ,  Ramesh Bhardwaj

IPC: H01M10/04

CPC classification number: H01M6/40 ,  H01M2/0202 ,  H01M2/026 ,  H01M2/1094 ,  H01M6/181 ,  H01M6/187 ,  H01M10/0436 ,  H01M2220/30 ,  H01M2300/0085 ,  Y10T156/10

Abstract: A battery includes an electrolyte disposed on a substantially planar substrate. The electrolyte has a first surface extending from the substrate and in contact with a cathode. The electrolyte has a second surface extending from the substrate and in contact with an anode. The second surface is opposite the first surface. The anode and the cathode are non-overlapping. The battery additionally includes a biocompatible protective layer that covers the electrolyte and at least portions of the anode and cathode. The battery can be disposed in an eye-mountable device or other device to power electronics in the device. The battery can be configured to be rechargeable.

Abstract translation: 电池包括设置在基本平坦的基板上的电解质。 电解质具有从衬底延伸并与阴极接触的第一表面。 电解质具有从基板延伸并与阳极接触的第二表面。 第二表面与第一表面相对。 阳极和阴极不重叠。 电池还包括覆盖电解质和至少部分阳极和阴极的生物相容性保护层。 电池可以设置在眼睛安装的装置或其他装置中以对装置中的电子设备供电。 电池可以配置为可充电。

公开(公告)号：US09084561B2

公开(公告)日：2015-07-21

申请号：US13919764

申请日：2013-06-17

Applicant: Google Inc.

Inventor： James Etzkorn ,  Zenghe Liu

IPC: A61B5/00 ,  A61B3/10 ,  A61B5/1477 ,  A61B5/1486 ,  G01N27/327 ,  A61B5/145

CPC classification number: A61B5/1486 ,  A61B3/101 ,  A61B5/0002 ,  A61B5/0004 ,  A61B5/002 ,  A61B5/14507 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1477 ,  A61B5/6821 ,  A61B5/7264 ,  A61B2560/0214 ,  G01N27/30 ,  G01N27/3271 ,  G01N27/4166 ,  G02C7/04

Abstract: An eye-mountable device includes an electrochemical sensor embedded in a polymeric material configured for mounting to a surface of an eye. The electrochemical sensor includes a working electrode, a reference electrode, and a reagent that selectively reacts with an analyte to generate a sensor measurement related to a concentration of the analyte in a fluid to which the eye-mountable device is exposed. The working electrode can have a first side edge and a second side edge. The reference electrode can be situated such that at least a portion of the first and second side edges of the working electrode are adjacent respective sections of the reference electrode.

Abstract translation: 一种可眼睛安装的装置包括嵌入聚合物材料中的电化学传感器，其被配置用于安装到眼睛的表面。 电化学传感器包括工作电极，参比电极和选择性地与分析物反应以产生与可眼睛安装的装置暴露于的流体中的分析物的浓度相关的传感器测量的试剂。 工作电极可以具有第一侧边缘和第二侧边缘。 参考电极可以被定位成使得工作电极的第一和第二侧边缘的至少一部分与参考电极的相应部分相邻。

公开(公告)号：US20150173680A1

公开(公告)日：2015-06-25

申请号：US14139855

申请日：2013-12-23

Applicant: Google Inc.

Inventor： James Etzkorn ,  Harvey Ho ,  Zenghe Liu

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1486

CPC classification number: A61B5/6821 ,  A61B5/0002 ,  A61B5/14532 ,  A61B5/1486 ,  Y10T29/49155

Abstract: A method may involve providing a conductive pattern on a bio-compatible layer. The conductive pattern may include a first conductive layer that comprises a first metal and a second conductive layer that comprises a second metal. The second conductive layer may be over the first conductive layer, and the first metal may be more malleable than the second metal. The method may also include mounting an electrical component to the conductive pattern to provide an electrochemical sensor. The electrochemical sensor may be configured for use in a body-mountable device.

Abstract translation: 一种方法可以涉及在生物相容层上提供导电图案。 导电图案可以包括包括第一金属的第一导电层和包括第二金属的第二导电层。 第二导电层可以在第一导电层之上，并且第一金属可以比第二金属更具有延展性。 该方法还可以包括将电气部件安装到导电图案以提供电化学传感器。 电化学传感器可被配置为用于体内安装的装置。

公开(公告)号：US20140371558A1

公开(公告)日：2014-12-18

申请号：US13919764

申请日：2013-06-17

Applicant: Google Inc.

Inventor： James Etzkorn ,  Zenghe Liu

IPC: A61B3/10

CPC classification number: A61B5/1486 ,  A61B3/101 ,  A61B5/0002 ,  A61B5/0004 ,  A61B5/002 ,  A61B5/14507 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1477 ,  A61B5/6821 ,  A61B5/7264 ,  A61B2560/0214 ,  G01N27/30 ,  G01N27/3271 ,  G01N27/4166 ,  G02C7/04

Abstract: An eye-mountable device includes an electrochemical sensor embedded in a polymeric material configured for mounting to a surface of an eye. The electrochemical sensor includes a working electrode, a reference electrode, and a reagent that selectively reacts with an analyte to generate a sensor measurement related to a concentration of the analyte in a fluid to which the eye-mountable device is exposed. The working electrode can have a first side edge and a second side edge. The reference electrode can be situated such that at least a portion of the first and second side edges of the working electrode are adjacent respective sections of the reference electrode.

Abstract translation: 一种可眼睛安装的装置包括嵌入聚合物材料中的电化学传感器，其被配置用于安装到眼睛的表面。 电化学传感器包括工作电极，参比电极和选择性地与分析物反应以产生与可眼睛安装的装置暴露于的流体中的分析物的浓度相关的传感器测量的试剂。 工作电极可以具有第一侧边缘和第二侧边缘。 参考电极可以被设置为使得工作电极的第一和第二侧边缘的至少一部分与参考电极的相应部分相邻。