Nucleic acid sequencing and electronic detection
    12.
    发明授权
    Nucleic acid sequencing and electronic detection 有权
    核酸测序和电子检测

    公开(公告)号:US08563240B2

    公开(公告)日:2013-10-22

    申请号:US12319168

    申请日:2008-12-31

    摘要: Embodiments of the present invention provide devices methods for sequencing DNA using arrays of reaction regions containing sensors to monitor changes in solutions or bound molecules contained in the reaction regions. Additional embodiments provide devices and methods for sequencing DNA using arrays of reaction regions that allow for optical monitoring of solutions in the reaction regions. Chemical amplification schemes that allow DNA to be sequenced in which multiple nucleotide addition reactions are performed to detect the incorporation of a base are disclosed. By sequencing DNA using parallel reactions contained in large arrays, DNA can be rapidly sequenced.

    摘要翻译: 本发明的实施方案提供了使用包含传感器的反应区域的阵列来测序DNA的装置方法,以监测反应区域中包含的溶液或结合分子的变化。 另外的实施方案提供了使用允许对反应区域中的溶液进行光学监测的反应区域阵列来测序DNA的装置和方法。 公开了允许进行多核苷酸加成反应进行DNA测序以检测碱基掺入的化学扩增方案。 通过使用大阵列中包含的平行反应测序DNA,可以快速测序DNA。

    SOLAR MODULE WITH BIMETAL BREAKER
    14.
    发明申请
    SOLAR MODULE WITH BIMETAL BREAKER 有权
    双模断路器太阳能模块

    公开(公告)号:US20120087054A1

    公开(公告)日:2012-04-12

    申请号:US13268297

    申请日:2011-10-07

    申请人: Kai Wu

    发明人: Kai Wu

    IPC分类号: H02H5/04

    CPC分类号: H02S40/34

    摘要: The primary objective of the present invention is to provide a solar module with a bimetal breaker, which comprises a solar module with terminal ribbons deposited on both sides of the solar module and inter-connecting ribbons extended and connected to the terminal ribbons, and a bimetal breaker being deposited on a joint of the terminal ribbon and the inter-connecting ribbon of the solar module. The bimetal breaker comprises a bimetal unit that is composed of two metal layers, and when the bimetal unit is heated, the bimetal unit will bend because of different thermal expansion coefficients and push the conducting terminals to separate from each other, so as to prevent the solar module from being damaged due to high temperature.

    摘要翻译: 本发明的主要目的是提供一种具有双金属断路器的太阳能模块,其包括太阳能模块,其具有沉积在太阳能模块两侧的端子带和延伸并连接到端子带的互连带和双金属片 断路器沉积在太阳能模块的端子带和连接带的接头上。 双金属断路器包括由两个金属层组成的双金属单元,并且当双金属单元被加热时,双金属单元将由于不同的热膨胀系数而弯曲,并且将导电端子彼此分离,以防止 太阳能组件由于高温而被损坏。

    Scalable model-based product matching
    15.
    发明授权
    Scalable model-based product matching 有权
    可扩展的基于模型的产品匹配

    公开(公告)号:US07979459B2

    公开(公告)日:2011-07-12

    申请号:US11763539

    申请日:2007-06-15

    IPC分类号: G06F17/30 G06Q10/00

    摘要: Aspects of the subject matter described herein relate to matching product information to products. In aspects, a product matching component receives product information. The product matching component normalizes the product information and obtains keywords from the product information. By querying a database of recognized products, the keywords are used to obtain a list of products that potentially match the product information. A confidence level is assigned to each of the potential matches in the list. A match may be returned for the highest matched product or for a selectable number of products whose confidence level(s) exceed a selectable threshold.

    摘要翻译: 本文描述的主题的方面涉及将产品信息与产品相匹配。 在方面,产品匹配组件接收产品信息。 产品匹配组件对产品信息进行规范化,并从产品信息中获取关键字。 通过查询已识别产品的数据库,关键字用于获取可能与产品信息相匹配的产品列表。 信任级别分配给列表中的每个潜在匹配项。 可以为最高匹配产品或可信度等级超过可选阈值的产品的可选数量返回匹配。

    SCALABLE MODEL-BASED PRODUCT MATCHING
    16.
    发明申请
    SCALABLE MODEL-BASED PRODUCT MATCHING 有权
    可扩展模型的产品匹配

    公开(公告)号:US20080313165A1

    公开(公告)日:2008-12-18

    申请号:US11763539

    申请日:2007-06-15

    IPC分类号: G06F7/06 G06F17/30

    摘要: Aspects of the subject matter described herein relate to matching product information to products. In aspects, a product matching component receives product information. The product matching component normalizes the product information and obtains keywords from the product information. By querying a database of recognized products, the keywords are used to obtain a list of products that potentially match the product information. A confidence level is assigned to each of the potential matches in the list. A match may be returned for the highest matched product or for a selectable number of products whose confidence level(s) exceed a selectable threshold.

    摘要翻译: 本文描述的主题的方面涉及将产品信息与产品相匹配。 在方面,产品匹配组件接收产品信息。 产品匹配组件对产品信息进行规范化,并从产品信息中获取关键字。 通过查询已识别产品的数据库,关键字用于获取可能与产品信息相匹配的产品列表。 信任级别分配给列表中的每个潜在匹配项。 可以为最高匹配产品或可信度等级超过可选阈值的产品的可选数量返回匹配。

    DETECTION OF DNA METHYLATION USING RAMAN SPECTROSCOPY
    17.
    发明申请
    DETECTION OF DNA METHYLATION USING RAMAN SPECTROSCOPY 审中-公开
    使用拉曼光谱法检测DNA甲基化

    公开(公告)号:US20080241828A1

    公开(公告)日:2008-10-02

    申请号:US11694427

    申请日:2007-03-30

    IPC分类号: C12Q1/68

    摘要: Epigenetic events such as DNA methylation play important roles in the regulation of gene expression. DNA methylation patterns have been found to differ between healthy and diseased tissue, such as healthy and cancerous tissue, thereby allowing DNA methylation to serve as a biomarker for disease states. Embodiments of the invention provide methods for detecting methylation patterns in DNA polymers. Methylation patterns are detected, in part, through the use of surface enhanced Raman spectroscopy (SERS). SERS provides a sensitive structure-based technique for chemical analysis.

    摘要翻译: 表观遗传事件如DNA甲基化在调控基因表达中起重要作用。 已经发现DNA甲基化模式在健康和患病组织如健康和癌组织之间不同,从而允许DNA甲基化作为疾病状态的生物标志物。 本发明的实施方案提供了检测DNA聚合物中甲基化模式的方法。 甲基化模式部分地通过使用表面增强拉曼光谱(SERS)来检测。 SERS提供了一种敏感的基于结构的化学分析技术。

    System and method for updating the firmware of a device in a storage network

    公开(公告)号:US20060277328A1

    公开(公告)日:2006-12-07

    申请号:US11145763

    申请日:2005-06-06

    申请人: Jacob Cherian Kai Wu

    发明人: Jacob Cherian Kai Wu

    IPC分类号: G06F3/00

    摘要: A system and method is disclosed for managing access command transmitted to a storage controller during the period that a device coupled to the storage controller is undergoing a firmware update. The storage controller manages access commands directed to the storage controller so that the access command may be managed in a manner that does not disrupt the firmware update processor or the completion of the access command itself. The storage controller enters a guard mode in which the firmware of the storage controller intercepts commands directed to the device undergoing a firmware update. Depending on the characteristics of the access command, the data of the command may be generated from other drives in a redundant drive array or the command may be saved to a cache or journal for later processing.

    Dual stage actuator systems for high density hard disk drives using annular rotary piezoelectric actuators
    19.
    发明授权
    Dual stage actuator systems for high density hard disk drives using annular rotary piezoelectric actuators 失效
    双级致动器系统,用于使用环形旋转压电致动器的高密度硬盘驱动器

    公开(公告)号:US06653763B2

    公开(公告)日:2003-11-25

    申请号:US09811112

    申请日:2001-03-16

    IPC分类号: H01L4108

    摘要: A piezoelectric actuator is disclosed including an annular piezoelectric element and a base. There is a gap along the radial direction of the annular piezoelectric element. One of the two ends, i.e., the fixed end of the said annular element, is connected to the base, while the other end is free. The base is made of piezoelectric materials. Furthermore, the annular element is divided into two or more annular parts along the direction of its circumference by the electrode patterns applied on its two opposite surface and/or its polarization directions. When driving voltages are applied, the actuator can generate roughly a rotary motion around the center of the annular piezoelectric element. The annular rotary actuator could be either a single plate or with multilayer structure. The present invention further relates to a dual stage head positioning actuator system of a hard disk drive with a plurality of disks and a plurality of vertically aligned head sliders mounted on distal ends of a plurality of suspensions via the annular piezoelectric actuators.

    摘要翻译: 公开了一种压电致动器,其包括环形压电元件和基座。 沿着环形压电元件的径向存在间隙。 两个端部中的一个,即所述环形元件的固定端连接到基座,而另一端是自由的。 基座由压电材料制成。 此外,通过施加在其两个相对表面和/或其偏振方向上的电极图案,环形元件沿其圆周方向被分成两个或更多个环形部分。 当施加驱动电压时,致动器可围绕环形压电元件的中心大致产生旋转运动。 环形旋转致动器可以是单板或具有多层结构。 本发明还涉及具有多个盘的硬盘驱动器的双级头定位致动器系统和经由环形压电致动器安装在多个悬架的远端上的多个垂直对准的头滑块。