摘要:
An embodiment of the invention relates to a device for detecting an analyte in a sample. The device comprises a fluidic network and an integrated circuitry component. The fluidic network comprises a sample zone, a cleaning zone and a detection zone. The fluidic network contains a magnetic particle and/or a signal particle. A sample containing an analyte is introduced, and the analyte interacts with the magnetic particle and/or the signal particle through affinity agents. A microcoil array or a mechanically movable permanent magnet is functionally coupled to the fluidic network, which are activatable to generate a magnetic field within a portion of the fluidic network, and move the magnetic particle from the sample zone to the detection zone. A detection element is present which detects optical or electrical signals from the signal particle, thus indicating the presence of the analyte.
摘要:
Embodiments of the present invention provide devices methods for sequencing DNA using arrays of reaction regions containing sensors to monitor changes in solutions or bound molecules contained in the reaction regions. Additional embodiments provide devices and methods for sequencing DNA using arrays of reaction regions that allow for optical monitoring of solutions in the reaction regions. Chemical amplification schemes that allow DNA to be sequenced in which multiple nucleotide addition reactions are performed to detect the incorporation of a base are disclosed. By sequencing DNA using parallel reactions contained in large arrays, DNA can be rapidly sequenced.
摘要:
An embodiment of the invention relates to a device for detecting an analyte in a sample. The device comprises a fluidic network and an integrated circuitry component. The fluidic network comprises a sample zone, a cleaning zone and a detection zone. The fluidic network contains a magnetic particle and/or a signal particle. A sample containing an analyte is introduced, and the analyte interacts with the magnetic particle and/or the signal particle through affinity agents. A microcoil array or a mechanically movable permanent magnet is functionally coupled to the fluidic network, which are activatable to generate a magnetic field within a portion of the fluidic network, and move the magnetic particle from the sample zone to the detection zone. A detection element is present which detects optical or electrical signals from the signal particle, thus indicating the presence of the analyte.
摘要:
The primary objective of the present invention is to provide a solar module with a bimetal breaker, which comprises a solar module with terminal ribbons deposited on both sides of the solar module and inter-connecting ribbons extended and connected to the terminal ribbons, and a bimetal breaker being deposited on a joint of the terminal ribbon and the inter-connecting ribbon of the solar module. The bimetal breaker comprises a bimetal unit that is composed of two metal layers, and when the bimetal unit is heated, the bimetal unit will bend because of different thermal expansion coefficients and push the conducting terminals to separate from each other, so as to prevent the solar module from being damaged due to high temperature.
摘要:
Aspects of the subject matter described herein relate to matching product information to products. In aspects, a product matching component receives product information. The product matching component normalizes the product information and obtains keywords from the product information. By querying a database of recognized products, the keywords are used to obtain a list of products that potentially match the product information. A confidence level is assigned to each of the potential matches in the list. A match may be returned for the highest matched product or for a selectable number of products whose confidence level(s) exceed a selectable threshold.
摘要:
Aspects of the subject matter described herein relate to matching product information to products. In aspects, a product matching component receives product information. The product matching component normalizes the product information and obtains keywords from the product information. By querying a database of recognized products, the keywords are used to obtain a list of products that potentially match the product information. A confidence level is assigned to each of the potential matches in the list. A match may be returned for the highest matched product or for a selectable number of products whose confidence level(s) exceed a selectable threshold.
摘要:
Epigenetic events such as DNA methylation play important roles in the regulation of gene expression. DNA methylation patterns have been found to differ between healthy and diseased tissue, such as healthy and cancerous tissue, thereby allowing DNA methylation to serve as a biomarker for disease states. Embodiments of the invention provide methods for detecting methylation patterns in DNA polymers. Methylation patterns are detected, in part, through the use of surface enhanced Raman spectroscopy (SERS). SERS provides a sensitive structure-based technique for chemical analysis.
摘要:
A system and method is disclosed for managing access command transmitted to a storage controller during the period that a device coupled to the storage controller is undergoing a firmware update. The storage controller manages access commands directed to the storage controller so that the access command may be managed in a manner that does not disrupt the firmware update processor or the completion of the access command itself. The storage controller enters a guard mode in which the firmware of the storage controller intercepts commands directed to the device undergoing a firmware update. Depending on the characteristics of the access command, the data of the command may be generated from other drives in a redundant drive array or the command may be saved to a cache or journal for later processing.
摘要:
A piezoelectric actuator is disclosed including an annular piezoelectric element and a base. There is a gap along the radial direction of the annular piezoelectric element. One of the two ends, i.e., the fixed end of the said annular element, is connected to the base, while the other end is free. The base is made of piezoelectric materials. Furthermore, the annular element is divided into two or more annular parts along the direction of its circumference by the electrode patterns applied on its two opposite surface and/or its polarization directions. When driving voltages are applied, the actuator can generate roughly a rotary motion around the center of the annular piezoelectric element. The annular rotary actuator could be either a single plate or with multilayer structure. The present invention further relates to a dual stage head positioning actuator system of a hard disk drive with a plurality of disks and a plurality of vertically aligned head sliders mounted on distal ends of a plurality of suspensions via the annular piezoelectric actuators.
摘要:
Host cells comprising recombinant vectors encoding the FK-520 polyketide synthase and FK-520 modification enzymes can be used to produce the FK-520 polyketide. Recombinant DNA constructs comprising one or more FK-520 polyketide synthase domains, modules, open reading frames, and variants thereof can be used to produce recombinant polyketide synthases and a variety of different polyketides with application as pharmaceutical and veterinary products.