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公开(公告)号:US20070100177A1
公开(公告)日:2007-05-03
申请号:US11506273
申请日:2006-08-11
申请人: Richard Clark , John Davenport , Jurgen Louis
发明人: Richard Clark , John Davenport , Jurgen Louis
IPC分类号: C10L1/08
CPC分类号: C10L10/02 , C10L10/12 , Y10S208/95
摘要: Fuel composition containing a blend of a non-Fischer-Tropsch derived, preferably petroleum derived, diesel base fuel and a Fischer-Tropsch derived kerosene fuel product, optionally together with a Fischer-Tropsch derived gas oil is provided. The Fischer Tropsch derived kerosene fuel product may be included for the purpose of improving the performance of a combustion engine or vehicle which is running or is intended to be run on the fuel composition. It may also be used to reduce vehicle emissions and/or improve the cold flow performance of the composition and/or increase the cetane number of the composition.
摘要翻译: 提供了包含非费 - 托衍生,优选石油衍生的柴油基础燃料和费 - 托衍生的煤油燃料产物的混合物的燃料组合物,任选地与费 - 托衍生的瓦斯油一起。 可以包括费托衍生的煤油燃料产品,目的是改善运行或预期在燃料组合物上运行的内燃机或车辆的性能。 它还可用于减少车辆排放和/或改善组合物的冷流性能和/或增加组合物的十六烷值。
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公开(公告)号:US20050245592A1
公开(公告)日:2005-11-03
申请号:US11158941
申请日:2005-06-22
申请人: Shuichi Suzuki , Makoto Kotake , Mitsuaki Miyamoto , Tetsuya Kawahara , Akiharu Kajiwara , Ieharu Hishinuma , Kazuo Okano , Syuhei Miyazawa , Richard Clark , Fumihiro Ozaki , Nobuaki Sato , Masanobu Shinoda , Atsushi Kamada , Itaru Tsukada , Fumiyoshi Matsuura , Yoshimitsu Naoe , Taro Terauchi , Yoshiaki Oohashi , Osamu Ito , Hiroshi Tanaka , Takashi Musha , Motoji Kogushi , Tsutomu Kawata , Toshiyuki Matsuoka , Hiroko Kobayashi , Ken-ichi Chiba , Akifumi Kimura , Naoto Ono
发明人: Shuichi Suzuki , Makoto Kotake , Mitsuaki Miyamoto , Tetsuya Kawahara , Akiharu Kajiwara , Ieharu Hishinuma , Kazuo Okano , Syuhei Miyazawa , Richard Clark , Fumihiro Ozaki , Nobuaki Sato , Masanobu Shinoda , Atsushi Kamada , Itaru Tsukada , Fumiyoshi Matsuura , Yoshimitsu Naoe , Taro Terauchi , Yoshiaki Oohashi , Osamu Ito , Hiroshi Tanaka , Takashi Musha , Motoji Kogushi , Tsutomu Kawata , Toshiyuki Matsuoka , Hiroko Kobayashi , Ken-ichi Chiba , Akifumi Kimura , Naoto Ono
IPC分类号: A61K20060101 , A61K31/403 , A61K31/4035 , A61K31/4178 , A61K31/4184 , A61K31/422 , A61K31/437 , A61K31/454 , A61K31/496 , A61K31/5377 , A61K31/538 , A61P20060101 , A61P7/02 , A61P9/00 , A61P9/10 , A61P9/12 , A61P11/00 , A61P11/06 , A61P13/12 , A61P19/10 , A61P25/00 , A61P29/00 , A61P35/00 , A61P43/00 , C07D20060101 , C07D207/22 , C07D207/24 , C07D207/26 , C07D207/263 , C07D207/267 , C07D207/34 , C07D209/44 , C07D209/52 , C07D209/54 , C07D209/62 , C07D209/96 , C07D213/73 , C07D213/74 , C07D233/46 , C07D233/66 , C07D233/88 , C07D233/90 , C07D235/30 , C07D249/14 , C07D261/14 , C07D401/04 , C07D401/06 , C07D401/10 , C07D401/12 , C07D403/04 , C07D403/06 , C07D403/10 , C07D403/12 , C07D405/06 , C07D409/04 , C07D409/06 , C07D409/10 , C07D413/06 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/06 , C07D417/10 , C07D471/04 , C07D487/04 , C07D491/10 , C07D498/04 , C07D521/00 , C07D209/48 , C07D471/02
CPC分类号: C07D209/44
摘要: A 2-iminopyrrolidine derivative represented by the formula: {wherein ring B represents a benzene ring, pyridine ring, etc.; R101-R103 represent hydrogen, halogen, C1-6 alkyl, etc.; R5 represents hydrogen, C1-6 alkyl, C1-6 alkoxy-C1-6 alkyl, etc.; R6 represents hydrogen, C1-6 alkyl, C1-6 alkyloxycarbonyl, etc.; Y1 represents a single bond, —CH2—, etc.; Y2 represents a single bond, —CO—, etc.; and Ar represents hydrogen, a group represented by the formula: [wherein R10-R14 represent hydrogen, C1-6 alkyl, hydroxyl, C1-6 alkoxy, etc.; and R11 and R12 or R12 and R13 may bond together to form a 5- to 8-membered heterocyclic ring], etc.}, or a salt thereof.
摘要翻译: 由下式表示的2-亚氨基吡咯烷衍生物:其中环B表示苯环,吡啶环等; R 101为-O-,卤素,C 1-6烷基等; R 5表示氢,C 1-6烷基,C 1-6烷氧基-C 1-6烷基 等等 R 6表示氢,C 1-6烷基,C 1-6烷氧基羰基等; Y 1表示单键,-CH 2 - 等; Y 2表示单键,-CO-等; 和Ar表示氢,由下式表示的基团:其中R 10 -R 14表示氢,C 1-6烷基,羟基 C 1-6烷氧基等; 并且R 11和R 12或R 12和R 13可以键合在一起形成5-8个 - 杂环]等,或其盐。
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公开(公告)号:US20050014833A1
公开(公告)日:2005-01-20
申请号:US10486396
申请日:2002-08-16
申请人: Richard Clark , Fumiyoshi Matsuura , Eita Emori , Masanobu Shinoda , Shunji Kasai , Hideki Yoshitomi , Kazuto Yamazaki , Takashi Inoue , Sadakazu Miyashita , Taro Hihara
发明人: Richard Clark , Fumiyoshi Matsuura , Eita Emori , Masanobu Shinoda , Shunji Kasai , Hideki Yoshitomi , Kazuto Yamazaki , Takashi Inoue , Sadakazu Miyashita , Taro Hihara
IPC分类号: A61P1/00 , A61P1/04 , A61P3/04 , A61P3/06 , A61P3/10 , A61P9/00 , A61P9/10 , A61P19/10 , A61P29/00 , A61P35/00 , A61P37/02 , C07C233/87 , C07C251/60 , C07D213/53 , C07D263/32 , C07D277/56 , C07D307/24 , C07D307/30 , C07D317/32 , C07D339/08 , C07D405/06 , C07D405/12 , C07D407/12 , C07D413/12 , C07D417/12 , C07D417/14 , C07C229/02 , A61K31/195
CPC分类号: C07D213/53 , C07C233/87 , C07C251/60 , C07C2601/02 , C07C2601/14 , C07D263/32 , C07D277/56 , C07D307/24 , C07D307/30 , C07D317/32 , C07D339/08 , C07D405/06 , C07D405/12 , C07D407/12 , C07D413/12 , C07D417/12 , C07D417/14
摘要: The present invention provides a novel compound having an excellent PPAR agonist action. More specifically, it provides a compound represented by the following formula, a salt thereof, an ester thereof or a hydrate of them. Wherein a, b and c are the same as or different from one another and each represents 0 to 4; R1 to R6 are the same as or different from one another and each represents a hydrogen atom, a hydroxyl group, a cyano group, a halogen atom, etc.; A1 and A2 are the same as or different from each other and each represents a single bond, an oxygen atom, etc.; L, M and T each represent a single bond, an alkylene group having one to six carbon atoms, etc.; W represents a carboxyl group; the partial structure represented by the formula: represents a single bond or a double bond; X represents a single bond, an oxygen atom, —NRX1CQ1O—, etc.; Y represents Y1—Y2— (wherein Y1 represents a 5 to 14-membered aromatic ring having one to four substituents, etc.; and Y2 represents a single bond or a 5 to 14-membered aromatic ring); and the ring Z represents a 5 to 14-membered aromatic ring which have one to four substituents selected form the above-mentioned Group A, may have one or more hetero atoms and may be partially saturated.
摘要翻译: 本发明提供具有优异的PPAR激动剂作用的新化合物。 更具体地,它提供由下式表示的化合物,其盐,其酯或它们的水合物。 其中a,b和c彼此相同或不同,各自表示0〜4; R 1〜R 6彼此相同或不同,表示氢原子,羟基,氰基,卤素原子等; A 1和A 2彼此相同或不同,各自表示单键,氧原子等; L,M和T各自表示单键,具有1〜6个碳原子的亚烷基等; W表示羧基; 由式表示的部分结构表示单键或双键; X表示单键,氧原子,-NR X 1 C 10 O等; Y表示Y 1 -Y 2 - (其中Y 1表示具有1〜4个取代基的5〜14元芳环等,Y 2表示单键或5〜14个 芳环); 并且环Z表示具有一至四个选自上述A组的取代基的5至14元芳环,可具有一个或多个杂原子并且可部分饱和。
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公开(公告)号:US20050004421A1
公开(公告)日:2005-01-06
申请号:US10892656
申请日:2004-07-16
申请人: John Pacella , Andrew Goldstein , Dennis Trumble , Richard Clark , Fred Moeller , George Magovern
发明人: John Pacella , Andrew Goldstein , Dennis Trumble , Richard Clark , Fred Moeller , George Magovern
CPC分类号: A61M1/102 , A61M1/1008 , A61M1/101 , A61M1/1031 , A61M1/1086 , A61M1/122 , A61M2205/3334
摘要: The present invention pertains to a blood pump device which comprises a blood pump having blood transport ports and cannulae connected to the ports. The blood pump device also comprises a coating material covering the junction between the inner surfaces of the ports and cannulae. This forms a smooth transition so blood can flow unimpeded therefrom and collection cavities for the blood are eliminated. The invention is also related to a method of producing a smooth coating. The present invention is a blood pump device comprising a second portion having a stator mechanism and a rotor mechanism disposed adjacent to and driven by the stator mechanism. The second portion has a journal disposed about the rotor mechanism to provide support therewith. The second portion has an impeller disposed in the chamber and a one-piece seal member for sealing about a shaft of the impeller. The seal member is fixedly attached to the journal so that the seal member is supported by the journal. The present invention is also related to means for providing power to the blood pump so that blood can be pumped through a cannulae. The providing means includes a controller having means for sensing pump failure and an output terminal for actuating a safety occluder in an event of pump failure. Preferably, there is a safety occluder device disposed about the cannulae and in communication with the output terminal. Preferably, the blood pump comprises a motor having stator mechanism and a rotor mechanism driven by the stator mechanism. The sensing means comprises means for determining back electromagnetic force within the stator mechanism. Preferably, the controlling means has means for providing signals indicate of stator current and rotor speed, respectively. The providing means is in communication with the means for determining back electromagnetic force in the stator mechanism.
摘要翻译: 本发明涉及一种血液泵装置,其包括具有血液输送口的血液泵和与端口连接的插管。 血液泵装置还包括覆盖端口的内表面和套管之间的接合处的涂层材料。 这形成平滑的过渡,因此血液可以不受阻碍地流动,消除了血液的收集腔。 本发明还涉及一种制备光滑涂层的方法。 本发明是一种血泵装置,包括具有定子机构的第二部分和与定子机构相邻并由定子机构驱动的转子机构。 第二部分具有围绕转子机构设置的轴颈,以便为其提供支撑。 第二部分具有设置在室中的叶轮和用于围绕叶轮的轴密封的一体式密封构件。 密封构件固定地连接到轴颈上,使得密封构件由轴颈支撑。 本发明还涉及用于向血液泵提供动力以使血液能够通过套管泵送的装置。 提供装置包括具有用于感测泵故障的装置的控制器和用于在泵故障的情况下致动安全闭塞器的输出端子。 优选地,存在围绕插管设置并与输出端子连通的安全闭塞器装置。 优选地,血泵包括具有定子机构的马达和由定子机构驱动的转子机构。 感测装置包括用于确定定子机构内的反向电磁力的装置。 优选地,控制装置具有分别提供定子电流和转子速度的信号的装置。 提供装置与用于确定定子机构中的反向电磁力的装置通信。
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公开(公告)号:USD484354S1
公开(公告)日:2003-12-30
申请号:US29169209
申请日:2002-10-16
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公开(公告)号:US5913613A
公开(公告)日:1999-06-22
申请号:US932556
申请日:1997-09-19
申请人: Kelly Ragsdale , Richard Clark , Cory Brady
发明人: Kelly Ragsdale , Richard Clark , Cory Brady
CPC分类号: E04H4/101
摘要: A system for deploying and recovering a cover over a space, like a swimming pool, has a reel housing that has extensions and a base that may be used to securely mount the reel housing in a receptacle, like a recess box. The extensions and the base may brace the reel housing which is made of inelastic or non deformable material which may be thick metal. The ropes are shortened in length so that there is no excess when the cover is in its fully open position. The ropes are selected to be inelastically deformable. A motor drives the rope reels in the reel housing and the drum for the cover. The clutch, that alternately engages the rope reels and the drum has a non sacrificial pin to ensure that the clutch and the reels or the drum remain driven and engaged.
摘要翻译: 用于在诸如游泳池的空间上部署和恢复盖子的系统具有卷轴壳体,该卷轴壳体具有延伸部和底座,其可用于将卷轴壳体牢固地安装在诸如凹槽的插座中。 延伸部和基部可以支撑由非弹性或不可变形的材料制成的卷轴壳体,其可以是厚金属。 绳子的长度被缩短,使得当盖子处于其完全打开位置时没有多余的绳索。 选择绳索是非弹性变形的。 电机驱动卷轴壳体中的绳卷轴和盖的滚筒。 交替地接合绳卷轴和滚筒的离合器具有非牺牲销,以确保离合器和卷轴或滚筒保持驱动和接合。
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公开(公告)号:US10298747B2
公开(公告)日:2019-05-21
申请号:US15295786
申请日:2016-10-17
申请人: Richard Clark
发明人: Richard Clark
摘要: A phone and system is disclosed which includes a programmed button(s) that initiates a telephone call from the phone to a second phone. In some embodiments, the phone may be a toy or instructional equipment configured to provide for example, children a device to learn how to converse over a telephone call with trusted parties. The phone may initiate a phone call request when a programmed button is pressed by connecting with a computing device that has a wireless local area network (LAN) transceiver and a connection to the telephone network (for example, a smartphone, a tablet, or a wearable device). The phone call request may then be re-routed through the telephone network to the second phone being called and communication may occur between the two phones through the intermediary device. Trusted and restricted communication may thus occur between parents/grandparents and children.
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公开(公告)号:US20130186664A1
公开(公告)日:2013-07-25
申请号:US13558066
申请日:2012-07-25
申请人: Albert Binder , Richard Clark , Sarah Duggan , Bernhard Sander
发明人: Albert Binder , Richard Clark , Sarah Duggan , Bernhard Sander
IPC分类号: B25D11/06
CPC分类号: B25D11/06 , B25D11/064 , B25D17/28 , B25D2250/245 , H02K7/08 , H02K33/16 , H02K41/031
摘要: A hand-held power tool is disclosed. The power tool has a linear motor with a rotor, an exciter piston that is coupled mechanically to the rotor, and a bearing device with a rotor mounting to support the longitudinal movement of the rotor and an exciter piston mounting to support the exciter piston. The rotor mounting and the exciter piston mounting form a three-point mounting, which is the sole bearing for the rotor and the exciter piston.
摘要翻译: 公开了一种手持电动工具。 电动工具具有带有转子的线性电动机,机械地连接到转子的励磁机活塞以及具有转子安装以支撑转子的纵向运动的轴承装置和用于支撑励磁机活塞的励磁机活塞安装。 转子安装和励磁机活塞安装形成三点安装,这是转子和励磁机活塞的唯一轴承。
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公开(公告)号:US08436009B2
公开(公告)日:2013-05-07
申请号:US13695665
申请日:2011-05-18
申请人: Richard Clark , Fumiyoshi Matsuura , Masanobu Shinoda , Shinsuke Hirota , Kazunobu Kira , Hiroshi Azuma , Atsushi Takemura , So Yasui , Kazutomi Kusano , Masaki Mikamoto , Takao Omae
发明人: Richard Clark , Fumiyoshi Matsuura , Masanobu Shinoda , Shinsuke Hirota , Kazunobu Kira , Hiroshi Azuma , Atsushi Takemura , So Yasui , Kazutomi Kusano , Masaki Mikamoto , Takao Omae
IPC分类号: A61K31/506 , C07D239/42
CPC分类号: C07D401/14 , C07D403/04
摘要: By oral administration of a compound represented by the following Formula (I): the blood level of Compound (IV): which has an excellent inhibitory action against blood coagulation factor VIIa and the anticoagulant action, reaches a level sufficient for expression of its pharmacological actions. Therefore, the compound of the present invention is useful as a therapeutic and/or prophylactic agent for diseases caused by thrombus formation.
摘要翻译: 通过口服给药由下式(I)表示的化合物:对血液凝固因子VIIa具有优异抑制作用的化合物(IV)的血液水平和抗凝血作用达到足以表达其药理作用的水平 。 因此,本发明的化合物可用作由血栓形成引起的疾病的治疗和/或预防剂。
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公开(公告)号:US20130053563A1
公开(公告)日:2013-02-28
申请号:US13695665
申请日:2011-05-18
申请人: Richard Clark , Fumiyoshi Matsuura , Masanobu Shinoda , Shinsuke Hirota , Kazunobu Kira , Hiroshi Azuma , Atsushi Takemura , So Yasui , Kazutomi Kusano , Masaki Mikamoto , Takao Omae
发明人: Richard Clark , Fumiyoshi Matsuura , Masanobu Shinoda , Shinsuke Hirota , Kazunobu Kira , Hiroshi Azuma , Atsushi Takemura , So Yasui , Kazutomi Kusano , Masaki Mikamoto , Takao Omae
IPC分类号: C07D403/04 , C07D401/14
CPC分类号: C07D401/14 , C07D403/04
摘要: By oral administration of a compound represented by the following Formula (I): the blood level of Compound (IV): which has an excellent inhibitory action against blood coagulation factor VIIa and the anticoagulant action, reaches a level sufficient for expression of its pharmacological actions. Therefore, the compound of the present invention is useful as a therapeutic and/or prophylactic agent for diseases caused by thrombus formation.
摘要翻译: 通过口服给药由下式(I)表示的化合物:对血液凝固因子VIIa具有优异抑制作用的化合物(IV)的血液水平和抗凝血作用达到足以表达其药理作用的水平 。 因此,本发明的化合物可用作由血栓形成引起的疾病的治疗和/或预防剂。
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