公开(公告)号：US20050264292A1

公开(公告)日：2005-12-01

申请号：US11180713

申请日：2005-07-14

申请人： Kazuya Okamoto ,  Yoshinori Hamamura ,  Yoshio Machida

发明人： Kazuya Okamoto ,  Yoshinori Hamamura ,  Yoshio Machida

IPC分类号： G01R33/341 ,  A61B5/055 ,  G01R33/3415 ,  G01V3/00

CPC分类号： G01R33/3415 ,  G01R33/3678

摘要： A magnetic resonance imaging apparatus acquires magnetic resonance signals by the PI method using an RF coil unit having basic coils serving as surface coils which are arrayed with at least two coils along a static magnetic field direction (z direction) and at least two coils along each of two orthogonal x, y directions. The coils are divided into an upper unit and a lower unit. The upper unit and lower unit are fixed by a band or the like to allow them to be mounted on an object to be examined. The signals detected by the respective surface coils are sent to a data processing system through independent receiver units and formed into a magnetic resonance image.

摘要翻译： 磁共振成像装置使用具有作为表面线圈的基本线圈的RF线圈单元，通过PI法获取磁共振信号，该线圈单元沿着静磁场方向（z方向）排列有至少两个线圈，并且沿着每个线圈具有至少两个线圈 两个正交的x，y方向。 线圈分为上部单元和下部单元。 上部单元和下部单元通过带状物等固定，以便将它们安装在被检查物体上。 由各个表面线圈检测的信号通过独立的接收器单元被发送到数据处理系统并形成磁共振图像。

公开(公告)号：US06765217B1

公开(公告)日：2004-07-20

申请号：US09302075

申请日：1999-04-28

申请人： Hiroshi Nishimura ,  Naoto Kihara ,  Kinya Kato ,  Toru Takagi ,  Akihiro Goto ,  Junji Ikeda ,  Kazuya Okamoto

发明人： Hiroshi Nishimura ,  Naoto Kihara ,  Kinya Kato ,  Toru Takagi ,  Akihiro Goto ,  Junji Ikeda ,  Kazuya Okamoto

IPC分类号： G01N2100

CPC分类号： H01J37/26 ,  G01N23/225 ,  H01J37/1471 ,  H01J37/226 ,  H01J37/265 ,  H01J2237/0492 ,  H01J2237/057 ,  H01J2237/1501 ,  H01J2237/2482 ,  H01J2237/2538 ,  H01J2237/262 ,  H01J2237/2806 ,  H01J2237/2817 ,  H01J2237/282 ,  H01J2237/2823 ,  H01J2237/2826 ,  H01J2237/30438

摘要： Charged-particle-beam (CPB) mapping projection-optical systems and adjustment methods for such systems are disclosed that can be performed quickly and accurately. In a typical system, an irradiation beam is emitted from a source, passes through an irradiation optical system, and enters a Wien filter (“E×B”). Upon passing through the E×B, the irradiation beam passes through an objective optical system and is incident on an object surface. Such impingement generates an observation beam that returns through the objective optical system and the E×B in a different direction to a detector via an imaging optical system. An adjustment-beam source emits an adjustment beam used for adjusting and aligning the position of, e.g., the object surface and/or the Wien's condition of the E×B. The adjustment beam can be off-axis relative to the objective-optical system. For such adjusting and aligning, fiducial marks (situated, e.g., in the plane of the object surface) can be used that are optimized for the CPB optical system and the off-axis optical system. Desirably, the image formed on the detector when electrical voltage and current are not applied to the E×B is in the same position as the image formed on the detector when electrical voltage and current are applied to the E×B. Also provided are “evaluation charts” for use in such alignments that do not require adjustment of the optical axis of the irradiation optical system, and from which the kinetic-energy distribution of the emitted adjustment beam is stable.

摘要翻译： 公开了可以快速且准确地执行这种系统的带电粒子束（CPB）映射投影光学系统和调整方法。 在典型的系统中，照射光束从光源发射，通过照射光学系统，并进入维恩滤光片（“ExB”）。 当通过ExB时，照射光束通过物镜光学系统并入射到物体表面上。 这种冲击产生观察光束，该观察光束经由成像光学系统通过物镜光学系统和ExB以不同的方向返回到检测器。 调整光束源发射用于调整和对准例如物体表面的位置和/或ExB的维恩状态的调节光束。 调节光束可以相对于物镜光学系统偏轴。 对于这种调整和对准，可以使用为CPB光学系统和离轴光学系统优化的基准标记（例如位于物体表面的平面中）。 理想地，当电压和电流未施加到ExB时，在检测器上形成的图像与当将电压和电流施加到ExB时形成在检测器上的图像位于相同的位置。 还提供了用于这种对准的“评估图”，其不需要调整照射光学系统的光轴，并且发射的调节光束的动能分布从该距离稳定。

公开(公告)号：US06707240B1

公开(公告)日：2004-03-16

申请号：US09890959

申请日：2001-09-28

申请人： Mamoru Nakasuji ,  Kazuya Okamoto

发明人： Mamoru Nakasuji ,  Kazuya Okamoto

IPC分类号： H01J115

CPC分类号： H01J3/024 ,  H01J37/075 ,  H01J2237/3175

摘要： An electron gun includes a plate-like main cathode 77 having an electron emitting surface 79 and a sub-cathode 81 provided toward the rear surface of the main cathode to heat the main cathode 77 by imparting an electron bombardment. The sub-cathode 81 is constituted of filaments 83 and 85 coiled in a double helix structure and the diameter of the sub-cathode 81 is larger than the diameter of the main cathode 77. As a result, the temperature at the peripheral area of the electron emitting surface 79 can be set higher than the temperature at the center, to achieve an electron beam with a uniform intensity distribution.

摘要翻译： 电子枪包括具有电子发射表面79的板状主阴极77和朝向主阴极的后表面设置的副阴极81，以通过施加电子轰击来加热主阴极77。 副阴极81由以双螺旋结构卷绕的细丝83和85构成，并且副阴极81的直径大于主阴极77的直径。因此， 电子发射表面79可以被设置为高于中心处的温度，以实现具有均匀强度分布的电子束。

公开(公告)号：US06291145B1

公开(公告)日：2001-09-18

申请号：US09038683

申请日：1998-03-09

申请人： Tadayosi Kokubo ,  Kazuya Okamoto ,  Hiroshi Ooki ,  Masato Shibuya ,  Soichi Owa

发明人： Tadayosi Kokubo ,  Kazuya Okamoto ,  Hiroshi Ooki ,  Masato Shibuya ,  Soichi Owa

IPC分类号： G03F524

CPC分类号： G03F7/70466 ,  G03F7/033 ,  G03F7/038 ,  G03F7/2022

摘要： Image-formation methods and photosensitive materials used in such methods are disclosed that form very high-resolution patterns. The photosensitive materials comprise an ingredient that is triggered by a radical to undergo a latent-image-forming reaction. The radicals are produced by photons from an illumination light. Alternatively, the ingredient is triggered by a reactive-intermediate compound that is activated by the exposure-produced radical. The photosensitive materials possess a non-linear sensitivity characteristic in which the latent-image reaction density increases according to the mth power (m>1) of the incident light intensity. The photosensitive material can be applied to a sensitive substrate for exposure. Multiple exposures of the sensitive substrate are performed using a projected mask pattern in the presence of a radical deactivator. The multiple exposures can be performed while: (a) changing the exposure intensity distribution on the photosensitive material, or (b) shifting the projected mask pattern and the sensitive substrate relative to each other by a specified amount, or (c) using a different projected mask pattern for each exposure.

摘要翻译： 公开了在这种方法中使用的图像形成方法和感光材料，其形成非常高分辨率的图案。 感光材料包括由自由基触发以进行潜像形成反应的成分。 自由基由照明光的光子产生。 或者，成分由被暴露产生的自由基活化的反应性中间体化合物触发。 感光材料具有根据入射光强度的第m次幂（m> 1）潜影反应密度增加的非线性灵敏度特性。 可以将感光材料施加到敏感基板上以进行曝光。 在存在自由基失活剂的情况下，使用投影的掩模图案来进行敏感基材的多次曝光。 可以执行多次曝光，同时：（a）改变感光材料上的曝光强度分布，或（b）将投影的掩模图案和敏感基板相对于彼此移动指定量，或（c）使用不同的 每次曝光的投影面具图案。

公开(公告)号：US5969362A

公开(公告)日：1999-10-19

申请号：US30653

申请日：1998-02-05

申请人： Shintaro Kawata ,  Kazuya Okamoto

发明人： Shintaro Kawata ,  Kazuya Okamoto

IPC分类号： H01J37/073 ,  H01J37/305 ,  H01J37/317 ,  H01J37/30 ,  H01J37/14

CPC分类号： B82Y10/00 ,  B82Y40/00 ,  H01J37/3177

摘要： An electron-beam exposure system includes: (1) a stage for supporting a wafer, (2) a planar electron-beam source that emits multiple electron beamlets toward the stage, (3) an electric-field generator for forming an electric field to accelerate the electrons in the electron beamlets, (4) a magnetic-field generator for forming a magnetic flux in the space between the planar electron-beam source and the wafer stage. The magnetic filed generator is structured and arranged such that the magnetic flux formed thereby is (1) substantially evenly distributed within a plane perpendicular to the optical axis, and (2) of increasing flux density, ranging from a first density in the vicinity of the planar electron-beam source, to a second density (greater than the first density) in the vicinity of the wafer stage. The electrons in the electron beamlets follow the lines of magnetic flux such that the beamlet width is decreased at the stage compared to the beamlet width at the planar electron-beam source. The electron beamlets are preferably individually switchable, on and off, by word lines and bit lines on the planar electron-beam source. To form a desired pattern on a wafer surface, the stage is moved through a small area, while the electron beamlets are modulated as needed to write the desired pattern.

摘要翻译： 电子束曝光系统包括：（1）用于支撑晶片的台，（2）朝向平台发射多个电子束的平面电子束源，（3）用于形成电场的电场发生器 加速电子束中的电子，（4）用于在平面电子束源和晶片台之间的空间中形成磁通量的磁场发生器。 磁场发生器的结构和布置使得由此形成的磁通量是（1）在垂直于光轴的平面内基本上均匀分布，以及（2）增加磁通密度，范围从第 平面电子束源在晶片台附近达到第二密度（大于第一密度）。 电子束中的电子遵循磁通线，使得在与平面电子束源处的子束宽度相比较的阶段，子束宽度减小。 电子子束优选地可以通过平面电子束源上的字线和位线单独地切换，打开和关闭。 为了在晶片表面上形成期望的图案，将载物台移动通过小的区域，同时根据需要对电子束进行调制以写入期望的图案。

公开(公告)号：US5916161A

公开(公告)日：1999-06-29

申请号：US713430

申请日：1996-09-13

申请人： Yasutoshi Ishihara ,  Kazuya Okamoto

发明人： Yasutoshi Ishihara ,  Kazuya Okamoto

IPC分类号： G01R33/48 ,  A61B5/00 ,  A61B5/055

CPC分类号： A61B5/015 ,  A61B5/055

摘要： A magnetic resonance imaging apparatus capable of measuring a temperature increase due to an application of RF magnetic fields for data acquisition purpose, and notifying an information on the measured temperature increase regularly to an operator, so as to secure the safety of a body to be examined. In this magnetic resonance imaging apparatus, the image data acquisition operation is controlled to acquire a phase information associated with a temperature change in an interior of the body to be examined, by displacing either an observation start timing or a radio frequency magnetic field application timing for a prescribed magnetic resonance signal in the magnetic resonance signal sequence from a normal timing for acquiring image data.

摘要翻译： 一种磁共振成像装置，其能够测量由于应用RF磁场而导致的温度升高以用于数据采集目的，并且向操作者通知关于所测量的温度升高的信息，以确保要检查的身体的安全性 。 在该磁共振成像装置中，控制图像数据获取操作，通过将观察开始定时或射频磁场施加定时移位，来取得与被检体内部的温度变化相关的相位信息， 从用于获取图像数据的正常定时的磁共振信号序列中规定的磁共振信号。

公开(公告)号：US5787105A

公开(公告)日：1998-07-28

申请号：US589125

申请日：1996-01-22

申请人： Kazuya Okamoto ,  Atsushi Yamada ,  Yoshiaki Nakano ,  Kunio Tada

发明人： Kazuya Okamoto ,  Atsushi Yamada ,  Yoshiaki Nakano ,  Kunio Tada

IPC分类号： G02B6/42 ,  H01S5/026 ,  H01S5/042 ,  H01S5/12 ,  H01S5/30 ,  H01S5/32 ,  H01S3/19

CPC分类号： G02B6/42 ,  H01S5/026 ,  H01S5/0422 ,  H01S5/12 ,  H01S5/305 ,  H01S5/3211

摘要： An integrated semiconductor laser apparatus is constructed in such an arrangement that a core layer is located in the proximity of an active layer so as to be in an evanescent-field area of light propagating in the active layer and that a carrier concentration of a second cladding layer is higher than that of a first cladding layer. Thus, most evanescent waves of light propagating in the core layer propagate in the first cladding layer of the low carrier concentration. Since the rate of evanescent waves absorbed by carriers is very low, the integrated semiconductor laser apparatus can propagate the light with small losses.

摘要翻译： 以这样的结构构成集成半导体激光装置，其中芯层位于有源层附近，以便处于在有源层中传播的光的消逝场区域中，并且第二包层的载流子浓度 层高于第一覆层的层。 因此，在芯层中传播的大部分消逝的光在低载流子浓度的第一包层中传播。 由于载流子吸收的ev逝波速度非常低，所以集成半导体激光装置可以以较小的损耗传播光。

公开(公告)号：US5208534A

公开(公告)日：1993-05-04

申请号：US564328

申请日：1990-08-08

申请人： Kazuya Okamoto ,  Kozo Satoh

发明人： Kazuya Okamoto ,  Kozo Satoh

IPC分类号： G01R33/3415 ,  G01R33/54 ,  G01R33/56

CPC分类号： G01R33/3415 ,  G01R33/54 ,  G01R33/56

摘要： A magnetic resonance imaging system includes a magnetic field applying section for applying a static field, gradient field pulses, and an RF field to an object to be examined, a signal detecting section, including a homogeneous coil and a plurality of surface coils arranged to surround a desired region of the object, for detecting magnetic resonance signals from the object through the homogeneous coil and the surface coils, and an image data processing section for obtaining an image of the desired region by synthesizing image data based on the magnetic resonance signals respectively detected by the surface coils upon weighting/adding processing. The system uses differential surface coils as the surface coils. A magnetic resonance signal is detected through the homogeneous coil within the same time interval in which magnetic resonance signals are detected through the surface coils. Weighting functions for weighting/adding processing of image data are determined on the basis of these magnetic resonance signals.

公开(公告)号：US4905316A

公开(公告)日：1990-02-27

申请号：US136337

申请日：1987-12-22

申请人： Kazuya Okamoto

发明人： Kazuya Okamoto

IPC分类号： G01R33/20 ,  A61B5/055 ,  A61B10/00 ,  G01R33/381 ,  G01R33/3815 ,  G01R33/385 ,  G01R33/421 ,  H01F6/00 ,  H01F7/20

CPC分类号： G01R33/421 ,  G01R33/3815 ,  G01R33/385

摘要： A magnetic field generating system for use in a magnetic resonance imaging system to apply a static magnetic field and additionally a gradient field and a high frequency field to a body under examination in order to excite a magnetic resonance and to collect magnetic resonance data about the magnetic resonance. The field generating system comprises a superconducting including magnet a superconducting coil for generating the static magnetic field, a gradient coil for generating the gradient field and a high frequency coil for generating the high frequency field. At least part of the superconducting magnet is made of a metal member, and at least part of the metal member is interposed between the superconducting coil the gradient coil provided with non-conductive sections for impeding an eddy current.

摘要翻译： 一种用于磁共振成像系统的磁场产生系统，用于向被检体内施加静磁场和附加梯度场和高频场，以便激发磁共振并收集有关磁共振的磁共振数据 谐振。 场产生系统包括超导，包括磁体，用于产生静磁场的超导线圈，用于产生梯度场的梯度线圈和用于产生高频场的高频线圈。 超导磁体的至少一部分由金属构件制成，并且金属构件的至少一部分插入在超导线圈之间，设置有用于阻止涡流的非导电部分的梯度线圈。

公开(公告)号：US08865907B2

公开(公告)日：2014-10-21

申请号：US13260063

申请日：2010-03-26

申请人： Yukihito Sumino ,  Kazuya Okamoto ,  Moriyasu Masui ,  Toshiyuki Akiyama

发明人： Yukihito Sumino ,  Kazuya Okamoto ,  Moriyasu Masui ,  Toshiyuki Akiyama

IPC分类号： C07D213/79 ,  C07D213/80 ,  C07D471/04 ,  C07D309/32 ,  C07D405/06 ,  C07D498/14

CPC分类号： C07D498/14 ,  C07D213/80 ,  C07D309/32 ,  C07D309/40 ,  C07D405/06 ,  C07D471/04 ,  C07D471/14

摘要： The present invention provides a pyrone derivative and a pyridone derivative, which are novel intermediates for synthesizing an anti-influenza drug, a method of producing the same, and a method of using the same.

摘要翻译： 本发明提供了作为合成抗流感药物的新中间体的吡喃酮衍生物和吡啶酮衍生物，其制造方法及其使用方法。