Abstract:
The invention relates to systems and methods for making intracycle adjustments to an osmotic agent concentration of peritoneal dialysate inside the peritoneal cavity of a patient. The systems and methods include osmotic agent sources, flow paths, and processors to adjust the osmotic agent concentration of dialysate in the peritoneal cavity of the patient. The method can include infusing peritoneal dialysate containing an osmotic agent into the peritoneal cavity of a patient; monitoring one or more patient parameters; and adjusting the osmotic agent concentration of the peritoneal dialysate in the peritoneal cavity of the patient by infusing a concentrated osmotic agent solution or by infusing sterile fluid into the peritoneal cavity of the patient using an on-line peritoneal dialysis machine. The system can include a peritoneal dialysis cycler.
Abstract:
The invention relates to systems and methods for monitoring the long term health of the peritoneum and catheter in a patient undergoing peritoneal dialysis (PD) treatment. The systems and methods include processors and sensors for determining changes in the peritoneum health or catheter of a PD patient to support analysis, replacement, and possible medical intervention. The method can include receiving a prior history of a patient; storing the prior history in a machine-readable storage medium, which when executed performs the steps of trending the one or more fluid parameters from the prior history; and determining a change in peritoneum health or catheter patency from the trended prior history. The system can include a peritoneal dialysis cycler having an infusion line and an effluent line; at least one sensor positioned in the infusion line, the effluent line, or combinations thereof; and a processor in communication with the sensor.
Abstract:
The invention relates to systems and methods for optimizing a peritoneal dialysate prescription based on one or more fluid characteristics sensed from a filtrate removed from a patient. The systems and methods include sensors, flow paths, and processors to adjust a peritoneal dialysate prescription and deliver peritoneal dialysis therapy to a patient based on the adjusted prescription. The method can include the steps of removing fluid from a peritoneal cavity of a patient; sampling one or more characteristics of the removed fluid; and adjusting a peritoneal dialysate prescription based on the one or more characteristics of the removed fluid. The system can include a peritoneal dialysate effluent line; at least one concentrate source fluidly connectable to the peritoneal dialysate flow path; and at least one sensor positioned in the peritoneal dialysate effluent line.
Abstract:
Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer of a sorbent material such as zirconium oxide and/or zirconium phosphate in a sorbent cartridge. The methods and apparatuses include passing solutions containing aqueous basic solutions through the zirconium oxide. The apparatus allows for recharging the zirconium oxide, and also for recharging zirconium phosphate, wherein the sorbent materials are contained in reusable sorbent modules.
Abstract:
A system and method for determining the amount of fluid to be removed from a dialysis patient is disclosed. The system utilizes sensors and a computer. The computer obtains the input parameters from the sensors, along with information added directly by the user, and performs a forward algorithm to determine a recommended change in patient fluid level. As fluid is removed, the effect of the removal on the parameters is detected by the sensors and re-transmitted back to the computer. The computer then performs a backward algorithm to refine the variables used in the forward algorithm and obtain more accurate results. The system and method provide for changing the amount of fluid removed from the patient based on the results of the algorithm and the data received from the sensors.
Abstract:
A dialysis authentication system comprising at least one dialysis component having at least one authentication component affixed thereon. The dialysis component can be any one of a dialyzer, sorbent cartridge, or recharger. The authentication component can be selected from the group comprising a radio-frequency identification marker, a bar code, a one-wire security component, and a wireless authentication component.
Abstract:
A module for optionally recharging sorbent materials in-line, including zirconium phosphate, with an optional bypass and conduits for a sorbent cartridge. The sorbent cartridge can have one or more modules contained therein having connectors connecting each of the modules. One or more of the modules can be reusable and the sorbent materials therein recharged.