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公开(公告)号：US11186731B2
公开(公告)日：2021-11-30
申请号：US15973193
申请日：2018-05-07
Applicant: President and Fellows of Harvard College
Inventor： Joanna Aizenberg , Michael Aizenberg , Jiaxi Cui , Stuart Dunn , Benjamin Hatton , Caitlin Howell , Philseok Kim , Tak Sing Wong , Xi Yao
IPC: C09D5/16 , A61L29/14 , A61L31/04 , A61L31/06 , A61L31/14 , C10M171/00 , C09D201/00 , A61L29/08 , B01D65/08 , B08B17/02 , B08B17/06 , C10M105/76 , B05D5/08 , C10N50/00 , C10N70/00
Abstract: The present disclosure describes a strategy to create self-healing, slippery self-lubricating polymers. Lubricating liquids with affinities to polymers can be utilized to get absorbed within the polymer and form a lubricant layer (of the lubricating liquid) on the polymer. The lubricant layer can repel a wide range of materials, including simple and complex fluids (water, hydrocarbons, crude oil and bodily fluids), restore liquid-repellency after physical damage, and resist ice, microorganisms and insects adhesion. Some exemplary applications where self-lubricating polymers will be useful include energy-efficient, friction-reduction fluid handling and transportation, medical devices, anti-icing, optical sensing, and as self-cleaning, and anti-fouling materials operating in extreme environments.
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公开(公告)号：US10265694B2
公开(公告)日：2019-04-23
申请号：US14900567
申请日：2014-06-30
Applicant: President and Fellows of Harvard College
Inventor： Joanna Aizenberg , Tanya Shirman , Nicolas Vogel , Mathias Kolle , Michael Aizenberg
Abstract: Methods for forming an interconnected network of solid material and pores, with metal residing only at the air/solid interface of the interconnected network structure are described. In certain embodiments, nanoparticle decorated sacrificial particles can be used as sacrificial templates for the formation of a porous structure having an interconnected network of solid material and interconnected network of pores. The nanoparticles reside predominantly at the air/solid interface and allow further growth and accessibility of the nanoparticles at defined positions of the interconnected structure. SEM and TEM measurements reveal the formation of 3D interconnected porous structures with nanoparticles residing predominantly at the air/solid interface of the interconnected structure.
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公开(公告)号：US10233334B2
公开(公告)日：2019-03-19
申请号：US15804809
申请日：2017-11-06
Applicant: President and Fellows of Harvard College
Inventor： Joanna Aizenberg , Michael Aizenberg , Sung Hoon Kang , Philseok Kim , Tak Sing Wong
IPC: B65D25/14 , C09D5/00 , A61L15/24 , A61L15/34 , A61L15/42 , A61L15/46 , A61L27/28 , A61L27/34 , A61L27/50 , A61L33/00 , A61L33/06 , C09D5/16 , F15D1/02 , F15D1/10 , B05D5/00 , B05D3/00 , F01D25/18 , F28F13/18 , H01L31/0236 , G02B1/14 , B01L3/00 , C10M105/54 , C10M105/56 , F28F19/02 , B05D5/08 , B01D69/02 , B63B59/04 , B64D15/00 , C02F1/44 , D06M13/00 , E04B1/92 , F01D25/02 , F16L57/00 , H01L31/0216
Abstract: The present disclosure describes a strategy to create self-healing, slippery liquid-infused porous surfaces. Roughened (e.g., porous) surfaces can be utilized to lock in place a lubricating fluid, referred to herein as Liquid B to repel a wide range of materials, referred to herein as Object A (Solid A or Liquid A). Slippery liquid-infused porous surfaces outperforms other conventional surfaces in its capability to repel various simple and complex liquids (water, hydrocarbons, crude oil and blood), maintain low-contact-angle hysteresis (
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公开(公告)号：US09651548B2
公开(公告)日：2017-05-16
申请号：US14268561
申请日：2014-05-02
Applicant: President and Fellows of Harvard College
Inventor： Joanna Aizenberg , Ximin He , Michael Aizenberg
IPC: G01N33/543 , B81B3/00 , B01L3/00 , G05D23/02 , C12P1/02 , C12P3/00 , C12Q1/66 , G01N33/58 , G01N33/86
CPC classification number: G01N33/54366 , B01L3/5027 , B01L2300/0636 , B01L2300/0877 , B01L2300/1822 , B01L2400/084 , B81B3/0032 , B81B2201/058 , C12P1/02 , C12P3/00 , C12Q1/66 , G01N33/582 , G01N33/86 , G05D23/021
Abstract: A chemo-mechano-chemical (C1-M-C2) system includes a base supporting an actuatable structure, said structure comprising a functionalized portion and being embedded in an environmentally responsive gel capable of volume change in response to an environmental stimulus; a first fluid layer disposed over the base and in contact with the actuatable structure, said first fluid layer comprising the environmentally responsive gel; and a second fluid layer in contact with the actuatable structure, wherein the layers are positioned such that the functionalized portion is in contact with the second layer in a first relaxed state and in contact with the first layer in a second actuated state and wherein the functionalized portion interacts with at least one of the layers to provide a chemical or physical response.
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公开(公告)号：US20160114046A1
公开(公告)日：2016-04-28
申请号：US14878578
申请日：2015-10-08
Applicant: President and Fellows of Harvard College
Inventor： Yevgeny Brudno , Cathal J. Kearney , Eduardo Silva , Michael Aizenberg , Brian Kwee , Rajiv Desai , Neel S. Joshi , David J. Mooney
IPC: A61K47/36 , A61K9/00 , A61K31/704
CPC classification number: A61K47/4823 , A61K9/0024 , A61K9/06 , A61K31/704 , A61K47/36 , A61K47/549 , A61K47/555 , A61K47/6903 , A61K49/0021 , A61K49/0054 , C12N15/113 , C12N2310/113 , C12N2310/315 , C12N2310/351 , C12N2320/32
Abstract: The present invention provides refillable drug delivery systems, as well as methods of refilling the systems, and methods of using them to treat diseases.
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Patent Agency Ranking
16.发明申请Structured Flexible Supports and Films for Liquid-Infused Omniphobic Surfaces 审中-公开用于液体注入式无所不在的表面的结构化柔性支撑和薄膜公开(公告)号：US20150209846A1
公开(公告)日：2015-07-30
申请号：US14414598
申请日：2013-07-12
Applicant: President and Fellows of Harvard College
Inventor： Joanna Aizanberg , Michael Aizenberg , Philseok Kim , Xi Yao
IPC: B08B17/06 , B32B3/26 , B32B27/08 , B32B27/32 , B32B27/28 , B32B5/16 , B05D3/02 , B05D3/10 , B05D3/12 , B05D1/36 , B32B37/24 , B32B37/12 , B32B38/00 , B32B38/06 , B32B37/00 , B32B7/12
CPC classification number: A61F13/537 , A61F13/15617 , A61F13/15699 , A61F2013/8455 , A61L15/42 , A61L15/50 , A61L29/06 , B05D1/36 , B05D3/0218 , B05D3/104 , B05D3/107 , B05D3/12 , B05D5/08 , B08B17/065 , B32B3/26 , B32B3/263 , B32B5/16 , B32B7/12 , B32B27/08 , B32B27/283 , B32B27/322 , B32B37/0038 , B32B37/1284 , B32B37/24 , B32B38/0004 , B32B38/0012 , B32B38/06 , B32B2037/1246 , B32B2037/243 , B32B2038/0016 , B32B2038/002 , B32B2255/10 , B32B2264/102 , B32B2307/746 , B32B2307/754 , B32B2405/00 , B32B2419/00 , B32B2419/04 , B32B2419/06 , B32B2457/12 , B32B2535/00 , B32B2551/00 , B32B2556/00 , B32B2590/00 , C09D5/1681 , C09D5/1693 , C09D171/00 , C09J7/203 , C09J2427/005 , C09J2483/006 , C10M107/38 , C10M177/00 , C10M2213/0623 , C10M2229/0415 , C10N2230/06 , C10N2250/18 , Y10T156/10 , Y10T428/24322 , Y10T428/24355 , Y10T428/24364
Abstract: An article with different surface properties on opposing sides is provided including a sheet having a first side and a second side, wherein the first side displays low adhesion properties, said first side comprising a roughened, porous or structured surface and a wetting liquid disposed upon the surface to form a stable liquid film; and wherein the second side displays a second property dissimilar from that of the first side. The article can be adhered to a variety of objects to impart anti-fouling properties.
Abstract translation: 提供了在相对侧具有不同表面性质的物品，包括具有第一侧和第二侧的片，其中第一侧显示低粘附性，所述第一面包括粗糙化，多孔或结构化表面，以及润湿液体， 表面形成稳定的液膜; 并且其中所述第二侧显示与所述第一侧不同的第二特性。 该物品可以粘附到各种物体上以赋予防污性能。
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公开(公告)号：US20150152270A1
公开(公告)日：2015-06-04
申请号：US14414291
申请日：2013-07-12
Applicant: President and Fellows of Harvard College
Inventor： Joanna Aizenberg , Michael Aizenberg , Jiaxi Cui , Stuart Dunn , Benjamin Hatton , Caitlin Howell , Philseok Kim , Tak Sing Wong , Xi Yao
IPC: C09D5/16 , C10M105/76 , B01D65/08 , B08B17/02 , B08B17/06
CPC classification number: C09D5/1637 , A61L29/085 , A61L29/14 , A61L31/04 , A61L31/049 , A61L31/06 , A61L31/14 , A61L2400/10 , B01D65/08 , B01D2321/00 , B05D5/08 , B08B17/025 , B08B17/065 , C08J2300/00 , C09D5/1675 , C09D5/1693 , C09D201/005 , C10M105/76 , C10M171/00 , C10M2203/1006 , C10M2229/025 , C10M2229/0515 , C10N2250/18 , C10N2270/00 , C08L83/04
Abstract: The present disclosure describes a strategy to create self-healing, slippery self-lubricating polymers. Lubricating liquids with affinities to polymers can be utilized to get absorbed within the polymer and form a lubricant layer (of the lubricating liquid) on the polymer. The lubricant layer can repel a wide range of materials, including simple and complex fluids (water, hydrocarbons, crude oil and bodily fluids), restore liquid-repellency after physical damage, and resist ice, microorganisms and insects adhesion. Some exemplary applications where self-lubricating polymers will be useful include energy-efficient, friction-reduction fluid handling and transportation, medical devices, anti-icing, optical sensing, and as self-cleaning, and anti-fouling materials operating in extreme environments.
Abstract translation: 本公开描述了创建自愈合，滑滑的自润滑聚合物的策略。 可以使用与聚合物亲和性的润滑液体在聚合物内吸收，并在聚合物上形成润滑液层（润滑液体）。 润滑层可以排斥各种材料，包括简单和复杂的流体（水，碳氢化合物，原油和体液），物理损坏后恢复拒水性，并抵抗冰，微生物和昆虫的粘附。 自润滑聚合物将有用的一些示例性应用包括在极端环境中操作的能量效率，摩擦减少流体处理和运输，医疗装置，防冰，光学感测以及作为自清洁和防污染材料。
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公开(公告)号：US11590483B2
公开(公告)日：2023-02-28
申请号：US16651951
申请日：2018-10-01
Applicant: President and Fellows of Harvard College
Inventor： Elijah Shirman , Tanya Shirman , Joanna Aizenberg , Michael Aizenberg
Abstract: Aspects of the present application provides for enhanced catalytic materials, which can feature multiple functional and/or catalytic species, and methods of their formation. The materials can include catalytic nanoparticles (NPs) partially embedded within a supporting matrix. Treatment of the material, e.g., thermal, optical, microwave, plasma, and/or chemical treatment, can lead to the formation of functionally, e.g., catalytic or co-catalytic, relevant chemical and structural/morphological species or features at the NP-matrix, NP-pore, and matrix-pore interfaces. The treated material is characterized by enhanced properties, e.g., greater mechanical stability.
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公开(公告)号：US11325114B2
公开(公告)日：2022-05-10
申请号：US16391053
申请日：2019-04-22
Applicant: President and Fellows of Harvard College
Inventor： Joanna Aizenberg , Tanya Shirman , Nicolas Vogel , Mathias Kolle , Michael Aizenberg
Abstract: Methods for forming an interconnected network of solid material and pores, with metal residing only at the air/solid interface of the interconnected network structure are described. In certain embodiments, nanoparticle decorated sacrificial particles can be used as sacrificial templates for the formation of a porous structure having an interconnected network of solid material and interconnected network of pores. The nanoparticles reside predominantly at the air/solid interface and allow further growth and accessibility of the nanoparticles at defined positions of the interconnected structure. SEM and TEM measurements reveal the formation of 3D interconnected porous structures with nanoparticles residing predominantly at the air/solid interface of the interconnected structure.
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公开(公告)号：US10450467B2
公开(公告)日：2019-10-22
申请号：US15879526
申请日：2018-01-25
Applicant: President and Fellows of Harvard College
Inventor： Joanna Aizenberg , Michael Aizenberg , Sung Hoon Kang , Philseok Kim , Tak Sing Wong
IPC: B05D3/00 , C09D5/00 , C09D5/16 , A61L15/24 , A61L15/34 , A61L15/42 , A61L15/46 , A61L27/28 , A61L27/34 , A61L27/50 , A61L33/00 , A61L33/06 , F15D1/02 , F15D1/10 , B05D5/00 , F01D25/18 , F28F13/18 , H01L31/0236 , G02B1/14 , B01L3/00 , B65D25/14 , C10M105/54 , C10M105/56 , F28F19/02 , B05D5/08 , B01D69/02 , B63B59/04 , B64D15/00 , C02F1/44 , D06M13/00 , E04B1/92 , F01D25/02 , F16L57/00 , H01L31/0216
Abstract: The present disclosure describes a strategy to create self-healing, slippery liquid-infused porous surfaces. Roughened (e.g., porous) surfaces can be utilized to lock in place a lubricating fluid, referred to herein as Liquid B to repel a wide range of materials, referred to herein as Object A (Solid A or Liquid A). Slippery liquid-infused porous surfaces outperforms other conventional surfaces in its capability to repel various simple and complex liquids (water, hydrocarbons, crude oil and blood), maintain low-contact-angle hysteresis (
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