公开(公告)号：US08968758B2

公开(公告)日：2015-03-03

申请号：US14253547

申请日：2014-04-15

Applicant: The Hong Kong University of Science and Technology Technology Transfer Center

Inventor： King Lun Yeung ,  Wai Kin Leung

IPC: A01N25/26 ,  A01N25/04 ,  A01N59/00 ,  A01N59/20 ,  A01N59/16

CPC classification number: A01N25/26 ,  A01N25/04 ,  A01N59/00 ,  A01N59/16 ,  A01N59/20 ,  A01N25/18 ,  A01N25/28 ,  A01N25/30 ,  A01N31/16 ,  A01N37/36 ,  A01N43/08 ,  A01N2300/00

Abstract: The present invention provides a method for preparing a material in the form of liquid for forming an antimicrobial surface coating with multi-level antimicrobial properties, comprising: encapsulating one or more volatile or gaseous biocides in two or more amphiphilic block copolymers to obtain a w/o/w double emulsion, and mixing the w/o/w double emulsion with one or more nonvolatile biocides, each of which is selected from the group consisting of a metal containing biocide, triclosan, a carboxylic acid, a sugar acid and a combination thereof.

Abstract translation: 本发明提供了一种制备液体形式的材料的方法，用于形成具有多级抗微生物性质的抗微生物表面涂层，其包括：将一种或多种挥发性或气态杀生物剂包封在两种或更多种两亲性嵌段共聚物中以获得aw / o / w双重乳液，并将w / o / w双重乳液与一种或多种非挥发性杀生物剂混合，每种非杀菌剂选自含有杀生物剂的金属，三氯生，羧酸，糖酸及其组合 。

公开(公告)号：US11945973B2

公开(公告)日：2024-04-02

申请号：US16874402

申请日：2020-05-14

Applicant: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： King Lun Yeung ,  Wei Han ,  Xizi Song ,  Joseph Kai Cho Kwan ,  Yutang Luo

IPC: C09D7/61 ,  B01D46/00 ,  B05D3/10 ,  C09D5/14 ,  C09J1/00

CPC classification number: C09D7/61 ,  B01D46/0028 ,  B05D3/10 ,  C09D5/14 ,  B05D2350/60 ,  C09J1/00

Abstract: The ionic liquid-based coating is a coating for both porous and nonporous materials. As non-limiting examples, a porous substrate coated with the ionic liquid-based coating may be used to disinfect and remove microorganisms from air and water, to provide an antimicrobial surface for preventing microbial contamination, or to enhance filtration efficiency of the porous material for airborne and waterborne particulate matter without increasing flow resistance. As a further non-limiting example, a nonporous substrate coated with the ionic liquid-based coating may be used to form a surface capable of self-disinfection from microorganisms contacting surface. The ionic liquid-based coating includes at least one ionic liquid, an adhesive, and at least one additive, which may be a disinfectant, a viscosity modifier, a pH buffer, a fragrance, or combinations thereof.

公开(公告)号：US10548854B2

公开(公告)日：2020-02-04

申请号：US14432634

申请日：2013-09-23

Applicant: The Hong Kong University of Science and Technology

Inventor： King Lun Yeung ,  Wai Kit Wong ,  Siu Ming Kwan ,  Li Yin Chau ,  Ho Yee Timothy Poon ,  Ming Hung Thomas Lee ,  Albert Hee Lum Chow

IPC: A61M37/00 ,  A61K9/70 ,  A61K9/00 ,  A61K31/196 ,  A61K38/28

Abstract: Transdermal patches and devices for delivery of therapeutic drug and/or cosmetic formulations through an intact or porated skin barrier are described. Active-infusion delivers controlled dosing over a period of time to provide long-term efficacy. Methods and devices for preparing active-infusion patches for controlled dose delivery by nonelectronic devices and methods of skin poration that is safe and painless are described.

公开(公告)号：US10238762B2

公开(公告)日：2019-03-26

申请号：US14385852

申请日：2013-03-19

Applicant: The Hong Kong University of Science and Technology

Inventor： King Lun Yeung ,  Shammi Akter Ferdousi ,  Wei Han

IPC: B01J32/00 ,  A61L2/238 ,  B82Y30/00 ,  B01J37/06 ,  B01J37/10 ,  B01J37/34 ,  B01J21/06 ,  B01J23/06 ,  B01J23/22 ,  B01J23/42 ,  B01J23/44 ,  B01J23/50 ,  B01J23/52 ,  B01J23/72 ,  B01J23/75 ,  B01J35/00 ,  B01J35/10 ,  B01J37/02 ,  C30B29/60 ,  C01G23/00 ,  C01G23/053 ,  C30B7/10 ,  C30B29/02 ,  B01D15/22 ,  B01J20/06 ,  B01J20/30 ,  B82Y40/00 ,  B82Y99/00

Abstract: A multi-walled titanium-based nanotube array containing metal or non-metal dopants is formed, in which the dopants are in the form of ions, compounds, clusters and particles located on at least one of a surface, inter-wall space and core of the nanotube. The structure can include multiple dopants, in the form of metal or non-metal ions, compounds, clusters or particles. The dopants can be located on one or more of on the surface of the nanotube, the inter-wall space (interlayer) of the nanotube and the core of the nanotube. The nanotubes may be formed by providing a titanium precursor, converting the titanium precursor into titanium-based layered materials to form titanium-based nanosheets, and transforming the titanium-based nanosheets to multi-walled titanium-based nanotubes.

公开(公告)号：US20150238433A1

公开(公告)日：2015-08-27

申请号：US14432634

申请日：2013-09-23

Applicant: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： King Lun Yeung ,  Wai Kit Wong ,  Siu Ming Kwan ,  Li Yin Chau ,  Ho Yee Timothy Poon ,  Ming Hung Thomas Lee ,  Albert Hee Lum Chow

IPC: A61K9/70 ,  A61K38/28 ,  A61M37/00 ,  A61K31/196

Abstract: Transdermal patches and devices for delivery of therapeutic drug and/or cosmetic formulations through an intact or porated skin barrier are described. Active-infusion delivers controlled dosing over a period of time to provide long-term efficacy. Methods and devices for preparing active-infusion patches for controlled dose delivery by nonelectronic means and methods of skin poration that is safe and painless are described.

Abstract translation: 描述了经皮贴片和用于递送治疗性药物和/或化妆品制剂通过完整或开放的皮肤屏障的装置。 主动输液在一段时间内提供控制剂量以提供长期疗效。 描述了通过非电子手段制备用于控制剂量递送的活性输注贴剂的方法和装置以及安全和无痛的皮肤赋形方法。

公开(公告)号：US20150050494A1

公开(公告)日：2015-02-19

申请号：US14385852

申请日：2013-03-19

Applicant: The Hong Kong University of Science and Technology

Inventor： King Lun Yeung ,  Shammi Akter Ferdousi ,  Wei Han

IPC: A61L2/238 ,  B01D15/22 ,  B01J20/30 ,  B01J21/06 ,  B01J20/06

CPC classification number: A61L2/238 ,  B01D15/22 ,  B01J20/06 ,  B01J20/3078 ,  B01J21/063 ,  B01J23/06 ,  B01J23/22 ,  B01J23/42 ,  B01J23/44 ,  B01J23/50 ,  B01J23/52 ,  B01J23/72 ,  B01J23/75 ,  B01J35/0013 ,  B01J35/002 ,  B01J35/004 ,  B01J35/1019 ,  B01J37/0201 ,  B01J37/06 ,  B01J37/10 ,  B01J37/346 ,  B82Y30/00 ,  B82Y40/00 ,  B82Y99/00 ,  C01G23/005 ,  C01G23/053 ,  C01P2002/82 ,  C01P2002/84 ,  C01P2002/85 ,  C01P2004/04 ,  C01P2004/13 ,  C01P2004/16 ,  C01P2004/20 ,  C01P2004/51 ,  C01P2004/53 ,  C01P2006/12 ,  C30B7/10 ,  C30B29/02 ,  C30B29/602 ,  Y10S977/734 ,  Y10S977/811 ,  Y10S977/845 ,  Y10S977/846 ,  Y10S977/847 ,  Y10S977/902 ,  Y10T428/2935

Abstract: A multi-walled titanium-based nanotube array containing metal or non-metal dopants is formed, in which the dopants are in the form of ions, compounds, clusters and particles located on at least one of a surface, inter-wall space and core of the nanotube. The structure can include multiple dopants, in the form of metal or non-metal ions, compounds, clusters or particles. The dopants can be located on one or more of on the surface of the nanotube, the inter-wall space (interlayer) of the nanotube and the core of the nanotube. The nanotubes may be formed by providing a titanium precursor, converting the titanium precursor into titanium-based layered materials to form titanium-based nanosheets, and transforming the titanium-based nanosheets to multi-walled titanium-based nanotubes.

Abstract translation: 形成包含金属或非金属掺杂剂的多壁钛基纳米管阵列，其中掺杂剂是位于表面，壁间空间和核心中的至少一个上的离子，化合物，簇和颗粒的形式 的纳米管。 该结构可以包括金属或非金属离子，化合物，簇或颗粒形式的多种掺杂剂。 掺杂剂可以位于纳米管的表面上的一个或多个，纳米管的内壁空间（中间层）和纳米管的核心之间。 纳米管可以通过提供钛前体形成，将钛前体转化成钛基层状材料以形成钛基纳米片，并将钛基纳米片转化为多壁钛基纳米管。