公开(公告)号：US07829555B1

公开(公告)日：2010-11-09

申请号：US09367261

申请日：1998-02-13

申请人： David Blake ,  Declan Naughton ,  Ged Adams ,  Margaret Adams, legal representative ,  Ian Stratford ,  Christopher Morris ,  Mohammed Jaffar ,  Matthew Naylor

发明人： David Blake ,  Declan Naughton ,  Ged Adams ,  Ian Stratford ,  Christopher Morris ,  Mohammed Jaffar ,  Matthew Naylor

IPC分类号： A61K31/573 ,  C07J5/00

CPC分类号： A61K47/559

摘要： The invention provides a method of targeting a drug to areas of hypoxic and/or ischemic tissue within the body in which the desired drug species is linked to a non-cytotoxic bioreductive carrier. Also provided by the invention are novel bioreductive conjugates comprising a non-cytotoxic bioreductive moiety with linked-thereto at least one therapeutic agent. The compounds of the invention are particularly suitable for the treatment of rheumatoid arthritis and other arthritic conditions, diabetes, atherosclerosis, stroke, sepsis, Alzheimer's disease and other neurological disorders, cancer, kidney disease, digestive diseases, liver disease, chronic periodontitis or ischemia following tissue transplantation.

摘要翻译： 本发明提供了将药物靶向体内缺氧和/或缺血组织的区域的方法，其中所需药物物种与非细胞毒性生物还原载体连接。 本发明还提供了包含与至少一种治疗剂连接的非细胞毒性生物还原性部分的新型生物还原性缀合物。 本发明的化合物特别适用于治疗类风湿性关节炎和其他关节炎病症，糖尿病，动脉粥样硬化，中风，败血症，阿尔茨海默病和其他神经障碍，癌症，肾脏疾病，消化系统疾病，肝病，慢性牙周炎或缺血后续 组织移植。

公开(公告)号：US06894278B1

公开(公告)日：2005-05-17

申请号：US10630110

申请日：2003-07-30

申请人： Frank E. Merrill ,  Christopher Morris

发明人： Frank E. Merrill ,  Christopher Morris

IPC分类号： H01J37/26

CPC分类号： H01J37/26 ,  H01J37/04 ,  H01J2237/04922 ,  H01J2237/262

摘要： A system capable of performing radiography using a beam of electrons. Diffuser means receive a beam of electrons and diffuse the electrons before they enter first matching quadrupoles where the diffused electrons are focused prior to the diffused electrons entering an object. First imaging quadrupoles receive the focused diffused electrons after the focused diffused electrons have been scattered by the object for focusing the scattered electrons. Collimator means receive the scattered electrons and remove scattered electrons that have scattered to large angles. Second imaging quadrupoles receive the collimated scattered electrons and refocus the collimated scattered electrons and map the focused collimated scattered electrons to transverse locations on an image plane representative of the electrons' positions in the object.

摘要翻译： 一种能够使用电子束进行射线照相的系统。 扩散器装置在电子进入第一匹配四极之前接收电子束并扩散电子，其中扩散电子在扩散电子进入物体之前被聚焦。 第一个成像四极体在被聚焦的扩散电子被物体散射以聚焦散射电子之后接收聚焦的漫射电子。 准直器意味着接收散射的电子并去除散射到大角度的散射电子。 第二成像四极杆接收准直的散射电子并重新聚焦准直的散射电子，并将聚焦的准直散射电子映射到代表物体中的电子位置的图像平面上的横向位置。

公开(公告)号：US20210030515A1

公开(公告)日：2021-02-04

申请号：US16981760

申请日：2019-03-29

申请人： Christopher Morris

发明人： Christopher Morris

IPC分类号： A61C3/02

摘要： Two new burs to be used in dentistry applications. The two burs are used one after the other to create a natural anatomy in restorations of teeth. One of the burs also reduces the need for anesthetic by providing for minimal contact with the dentin while removing the enamel when cutting into a tooth.

公开(公告)号：US10772711B2

公开(公告)日：2020-09-15

申请号：US15580660

申请日：2016-07-15

申请人： Christopher Morris

发明人： Christopher Morris

IPC分类号： A61C13/00 ,  A61C13/275

摘要： A reinforcement bar combination for a direct dental bridge, the reinforcement bar combination including: first and second elongate bars, each of the first and second elongate bars contacting a single occlusal preparation formed in a single abutment tooth and each of the first and second elongate bars having an end positioned on a central pad of a third elongate bar to form a reinforcement scaffold. The first elongate bar is a first elongate torque bar that is optionally bent. The second elongate bar is a second elongate torque bar that is optionally bent. The third elongate bar is a proximal bar including a central planar pad bound by a perimeter, a coronal facing surface and an apical facing surface, a first insertion arm extending in a mesial direction from the perimeter of the pad, a second insertion arm extending in a distal direction from the perimeter of the pad; a first vertical sidewall extending in a coronal direction from the coronal oriented surface of the pad; a second vertical sidewall extending in a coronal direction from the coronal oriented surface of the pad. A method of using of the reinforcement bar combination to produce a direct dental bridge is also described.

公开(公告)号：US20170159921A1

公开(公告)日：2017-06-08

申请号：US14959462

申请日：2015-12-04

申请人： Christopher Morris

发明人： Christopher Morris

IPC分类号： F21V23/04 ,  F41A35/00 ,  F21V23/02

CPC分类号： F21V23/04 ,  F21V23/02 ,  F21V33/0076 ,  F21Y2115/10 ,  F41A3/66 ,  F41A35/00 ,  F41C23/10 ,  F41C23/16

摘要： Various means are provided which enable a user to individualize the appearance of a firearm and further enhance visibility of the various elements comprising the firearm in low light. More particularly, the firearm may comprise a serialized receiver and at least one of a barrel, upper receiver, grip, hand guard, and buttstock defining firearm accessories. A light source, means for distributing the light, a power source, and means for activating the light source are then provided to permit a user to selectively illuminate any of the elements comprising the firearm. The light source and means for distributing the light source may, for example, be disposed on a skin adhesible the serialized receiver and firearm accessories, on a clip slideably mateable with any of the serialized receiver and firearm accessories, or even integrated directly into the body of any of the firearm accessories and serialized receiver.

公开(公告)号：US08608965B2

公开(公告)日：2013-12-17

申请号：US12918746

申请日：2009-02-20

申请人： Christopher Morris ,  James Murcott ,  Jonathan Tomlinson ,  Richard Tomlinson

发明人： Christopher Morris ,  James Murcott ,  Jonathan Tomlinson ,  Richard Tomlinson

IPC分类号： C02F3/28 ,  B01F13/02

CPC分类号： C12M27/04 ,  B01F7/00208 ,  B01F13/0216 ,  B01F15/0289 ,  C12M21/04 ,  Y02E50/343

摘要： A gas bubble agitated mixing system for viscous fluids comprising: a container (1) in which a viscous fluid (2) may be held; one or more gas pipes (6), each gas pipe having an outlet (8) arranged to introduce gas bubbles (9) into the base region of the container (1), said gas bubbles (9) being of a size suitable to agitate the viscous fluid (2). The system also comprises a moveable carrier arm (4) upon which said one or more gas pipe outlets (8) are mounted; and wherein the movement of the carrier arm (4) causes the position at which each outlet (8) introduces gas bubbles (9) into the container (1) to vary over time.

摘要翻译： 一种用于粘性流体的气泡搅拌混合系统，包括：容器（1），其中可以保持粘性流体（2）; 一个或多个气体管道（6），每个气体管道具有布置成将气泡（9）引入容器（1）的基部区域中的出口（8），所述气泡（9）的尺寸适于搅拌 粘性流体（2）。 该系统还包括可移动的承载臂（4），所述一个或多个气体管道出口（8）安装在该可移动的承载臂上; 并且其中所述承载臂（4）的运动导致每个出口（8）将气泡（9）引入所述容器（1）中的位置随时间变化。

公开(公告)号：US20080265156A1

公开(公告)日：2008-10-30

申请号：US11977410

申请日：2007-10-24

申请人： Christopher Morris ,  Andrew Mcleod Fraser ,  Larry Joe Schultz ,  Konstantin N. Borozdin ,  Alexei Vasilievich Klimenko ,  Michael James Sossong ,  Gary Blanpied

发明人： Christopher Morris ,  Andrew Mcleod Fraser ,  Larry Joe Schultz ,  Konstantin N. Borozdin ,  Alexei Vasilievich Klimenko ,  Michael James Sossong ,  Gary Blanpied

IPC分类号： H01J47/00

CPC分类号： G01N23/201 ,  G01N23/20 ,  G01V5/0025 ,  G01V5/0075 ,  G06F17/18

摘要： Methods, apparatus and systems for detecting charged particles and obtaining tomography of a volume by measuring charged particles including measuring the momentum of a charged particle passing through a charged particle detector. Sets of position sensitive detectors measure scattering of the charged particle. The position sensitive detectors having sufficient mass to cause the charged particle passing through the position sensitive detectors to scatter in the position sensitive detectors. A controller can be adapted and arranged to receive scattering measurements of the charged particle from the charged particle detector, determine at least one trajectory of the charged particle from the measured scattering; and determine at least one momentum measurement of the charged particle from the at least one trajectory. The charged particle can be a cosmic ray-produced charged particle, such as a cosmic ray-produced muon. The position sensitive detectors can be drift cells, such as gas-filled drift tubes.

摘要翻译： 用于检测带电粒子的方法，装置和系统，并通过测量带电粒子来测量体积的断层摄影，包括测量通过带电粒子检测器的带电粒子的动量。 位置敏感检测器的集合测量带电粒子的散射。 位置敏感检测器具有足够的质量以使带电粒子通过位置敏感检测器散射在位置敏感检测器中。 控制器可以被适配和布置成从带电粒子检测器接收带电粒子的散射测量，从测量的散射中确定带电粒子的至少一个轨迹; 并且从所述至少一个轨迹确定所述带电粒子的至少一个动量测量。 带电粒子可以是宇宙射线产生的带电粒子，例如宇宙射线产生的μ子。 位置敏感检测器可以是漂移电池，例如充气漂移管。

公开(公告)号：US20060203010A1

公开(公告)日：2006-09-14

申请号：US11079781

申请日：2005-03-14

申请人： Peter Kirchner ,  Christopher Morris

发明人： Peter Kirchner ,  Christopher Morris

IPC分类号： G09G5/00

CPC分类号： G09G5/397 ,  G09G3/003

摘要： A method for creating composite images of multiple objects using standard commodity graphics cards is provided that eliminates the need for expensive specialty graphics hardware for generating real-time renderings of the composite images. After the desired composite image and the objects contained in the composite image are identified, a volume rendered image of a first object is obtained. In addition, at least a first geometric representation and a second geometric representation of a second object based upon a desired composite image of the first and second objects are generated. These geometric representations are preferably polygonal representations. The volume rendered image and the geometric representations are used to create a plurality of composite image components. Each composite image component contains at least one of the volume rendered image, the first geometric representation and the second geometric representation. The composite image components are blended to create the desired composite image.

摘要翻译： 提供了使用标准商品图形卡创建多个对象的合成图像的方法，其消除了对用于生成合成图像的实时渲染的昂贵的专业图形硬件的需要。 在所需的合成图像和包含在合成图像中的对象被识别之后，获得第一对象的体绘制图像。 此外，生成基于第一和第二对象的期望的合成图像的第二对象的至少第一几何表示和第二几何表示。 这些几何表示优选为多边形表示。 体积渲染图像和几何表示用于创建多个合成图像分量。 每个合成图像分量包含体绘制图像，第一几何表示和第二几何表示中的至少一个。 将合成图像分量混合以产生期望的合成图像。

公开(公告)号：US20180078073A1

公开(公告)日：2018-03-22

申请号：US15269857

申请日：2016-09-19

申请人： Christopher Morris

发明人： Christopher Morris

IPC分类号： A47H1/00 ,  A47H1/102 ,  A47H1/12 ,  A47H1/18 ,  F16M13/02 ,  F16B2/22 ,  F16B2/08

CPC分类号： F16B2/08 ,  A47H1/142 ,  A47H1/144 ,  F16M13/022

摘要： Systems and apparatuses for hanging articles while avoiding removal and/or damage to pre-installed supports and even surfaces are provided. In an embodiment, a device comprises a body configured to mechanically rest on or grip a portion of the pre-installed support, or even to be forcibly strapped to the pre-installed support. Additionally, a linking member, such as a clip, groove, channel, or hook, may be disposed along the body to join an article to the support. In practice, a plurality of devices may be applied to a variety of different types of head rails and other supports to join, for example, curtains to the head rail or other support, whether by forcibly gripping such curtains or supportively receiving a rod fitted with curtains.

公开(公告)号：US20130199831A1

公开(公告)日：2013-08-08

申请号：US13366436

申请日：2012-02-06

申请人： Christopher Morris

发明人： Christopher Morris

IPC分类号： H05K1/16 ,  H05K13/04

CPC分类号： H05K13/0015 ,  B23K1/0016 ,  B23K1/20 ,  H01L24/05 ,  H01L24/13 ,  H01L24/81 ,  H01L24/95 ,  H01L2224/0401 ,  H01L2224/05644 ,  H01L2224/05647 ,  H01L2224/05655 ,  H01L2224/13111 ,  H01L2224/29111 ,  H01L2224/81002 ,  H01L2224/81085 ,  H01L2224/81444 ,  H01L2224/81447 ,  H01L2224/81455 ,  H01L2224/95001 ,  H01L2224/95085 ,  H01L2224/95133 ,  H01L2924/0132 ,  H01L2924/10156 ,  H01L2924/15788 ,  H05K3/303 ,  H05K3/3436 ,  H05K13/027 ,  H05K13/04 ,  H05K2201/083 ,  H05K2203/04 ,  H05K2203/048 ,  H05K2203/0776 ,  H05K2203/104 ,  Y02P70/613 ,  H01L2924/01082 ,  H01L2924/01083 ,  H01L2924/0105 ,  H01L2924/00

摘要： A method and apparatus for self-assembling a part on a substrate are disclosed herein. In some embodiments, a method includes placing a substrate having a first binding site capable of generating a first magnetic field and having a first shaped surface with a first droplet conformably disposed thereon into a first fluid; placing a part having a second binding site capable of generating a second magnetic field and having a second shaped surface with a second droplet conformably disposed on the second shaped surface into the first fluid; and attracting the part towards the first binding site such that an equilibrium is formed between an attractive force and a repulsive force such that the part is free to rotate about the first binding site to minimize the repulsive force when the first and second shaped surfaces rotate into an alignment causing the part to aligned with the first binding site.

摘要翻译： 本文公开了一种用于自组装衬底上的部件的方法和装置。 在一些实施例中，一种方法包括放置具有能够产生第一磁场的第一结合位点的基底，并具有第一成形表面，其中第一液滴顺应地设置在第一流体中; 放置具有能够产生第二磁场的第二结合位点的部分，并具有第二成形表面，其中第二液滴在第二成形表面上顺应地设置在第一流体中; 并且将部分吸引到第一结合部位，使得在吸引力和排斥力之间形成平衡，使得部件围绕第一结合部位自由旋转，以使当第一和第二成形表面旋转时的排斥力最小化 使部分与第一结合位点对准的对准。