ENZYMATICALLY-CLEAVABLE GLYCIDYL METHACRYLATE HYALURONIC ACID

    公开(公告)号:US20240207420A1

    公开(公告)日:2024-06-27

    申请号:US18555956

    申请日:2022-04-20

    摘要: Disclosed herein is a hydrogel comprising hyaluronic acid polymers that are at least partially crosslinked with fibrinogen molecules. Also disclosed is a composition comprising a glycidyl methacrylate hyaluronic acid monomer chemically conjugated to a fibrinogen molecule. Also disclosed is a method for producing a hydrogel that involves combining the disclosed composition containing GMHA-Fib precursors with an effective amount of a photoinitiator and light (e.g. UV light) to crosslink unconjugated methacrylate sites through free-radical polymerization. Also disclosed is a method for treating a subject with a peripheral nerve injury that involves implanting the disclosed hydrogel at the site of the injury to promote neural regeneration.

    BLOCKCHAIN-GIS BASED FRAMEWORK FOR LAND REGISTRATION

    公开(公告)号:US20240202847A1

    公开(公告)日:2024-06-20

    申请号:US18541637

    申请日:2023-12-15

    IPC分类号: G06Q50/16 G06Q50/18

    CPC分类号: G06Q50/167 G06Q50/18

    摘要: The present disclosure presents blockchain-GIS based systems and methods for land registration. One such method, among others, comprises receiving, by one or more computing devices on a distributed ledger network, a land parcel record comprising geocoded information with a georeferenced map of the land parcel; validating, by the one or more computing devices using a smart contract, the land parcel record against a geo-spatial description of the land parcel in one or more municipal records; adding, by the one or more computing devices, the land parcel record as a block in a distributed ledger of the distributed ledger network with other land parcel records of the municipality; and transmitting, by the one or more computing devices, an electronic confirmation of ownership of the land parcel to the landowner.

    PREVENTION THROUGH DESIGN ENVIRONMENTAL MATERIAL INTELLIGENCE CENTER

    公开(公告)号:US20240119202A1

    公开(公告)日:2024-04-11

    申请号:US18545613

    申请日:2023-12-19

    摘要: The present disclosure presents systems and methods for building infrastructure and infection prevention data analysis. One such method comprises building contents of an electronic repository of performance metrics related to material pathogen propagation or reduction; assigning, via machine learning, a performance score or grade to a certain infrastructure building material based on the performance metrics associated with the building material; and predicting and outputting, via the machine learning, a risk associated with a building based on its infrastructure building materials, wherein the infrastructure building materials comprises the certain infrastructure building material.

    High efficiency metasurface-based multi-scale wireless power transfer

    公开(公告)号:US11888327B2

    公开(公告)日:2024-01-30

    申请号:US17705734

    申请日:2022-03-28

    IPC分类号: H02J50/12 H02J50/00

    CPC分类号: H02J50/12 H02J50/005

    摘要: The present disclosure provides wireless power transfer systems and methods. One such system includes a transmitter comprising a transmitter coil coupled to a power source and a transmitter metasurface slab positioned on a front side of the transmitter coil that is configured to amplify and focus a magnetic field generated by the transmitter coil towards a receiver in a non-contact manner. In such a system, the receiver comprises a receiver coil coupled to a load and a receiver metasurface slab positioned on a front side of the receiver coil configured to amplify and focus a magnetic field generated by the transmitter coil towards the receiver coil in a non-contact manner. Other systems and methods are also provided.