公开(公告)号：US20070137314A1

公开(公告)日：2007-06-21

申请号：US10545820

申请日：2004-02-16

申请人： David Watson ,  Lewis Jones ,  James Kovach

发明人： David Watson ,  Lewis Jones ,  James Kovach

IPC分类号： G01N1/38 ,  G01N35/02 ,  G01N15/10

CPC分类号： G01N15/10 ,  G01N1/2035 ,  G01N1/38 ,  G01N35/085 ,  G01N2001/1012 ,  G01N2001/383 ,  G01N2015/025 ,  G01N2015/1087 ,  G01N2015/1409 ,  G01N2015/1493 ,  G01N2035/1032 ,  Y10T436/25625

摘要： A multi-stage dilution device, comprising a first stage dilution apparatus (A), and a second stage dilution apparatus (B), each of the stage dilution device comprising: (i) a housing (1) having a diluent inlet (7); (ii) a sample inlet (2) having a sample introducer within the housing (1) adapted to introduce the sample at an introducer point (4) within the housing (1); and, (iii) a mixing conduit (5) mounted at least partially within the housing (1), the mixing conduit (5) having an inlet section comprising a mouth (10), and a fluid outlet (8), and a throat section (9) capable of producing a pressure drop within the mixing conduit (5), the pressure drop being sufficient to draw sample through the sample inlet (2); the introducer point (4) of the sample inlet (2) being proximate the mixing conduit inlet; and wherein the fluid output (8) of the first stage dilution apparatus (A) is in communication with the sample inlet (2) of the second stage dilution apparatus (B). A method of diluting a sample is also disclosed.

摘要翻译： 一种多级稀释装置，包括第一级稀释装置（A）和第二级稀释装置（B），每种级稀释装置包括：（i）具有稀释剂入口（7）的壳体（1） ; （ii）样品入口（2），其具有在所述壳体（1）内的样品引入器，适于将所述样品引入所述壳体（1）内的导引点（4）; 以及（iii）至少部分地安装在所述壳体（1）内的混合管道（5），所述混合管道（5）具有包括口（10）和流体出口（8）的入口部分，以及喉部 能够在所述混合管道（5）内产生压降的部分（9），所述压降足以将样品通过所述样品入口（2）; 样品入口（2）的导引点（4）靠近混合导管入口; 并且其中所述第一级稀释装置（A）的流体输出（8）与所述第二级稀释装置（B）的样品入口（2）连通。 还公开了稀释样品的方法。

公开(公告)号：US20060256340A1

公开(公告)日：2006-11-16

申请号：US11414839

申请日：2006-05-01

申请人： Frans Hansen ,  Martin Glensbjerg ,  Borkur Arnvidarson ,  Jesper Jeppesen

发明人： Frans Hansen ,  Martin Glensbjerg ,  Borkur Arnvidarson ,  Jesper Jeppesen

IPC分类号： G01N21/00

CPC分类号： G01N15/1459 ,  B01L3/5027 ,  G01N15/1463 ,  G01N21/31 ,  G01N21/59 ,  G01N21/6428 ,  G01N21/6458 ,  G01N21/76 ,  G01N33/04 ,  G01N2015/025 ,  G01N2015/1452 ,  G01N2015/1486 ,  G01N2021/5957 ,  G01N2021/6491

摘要： The present invention relates to a method for the assessment of quantity and quality parameters of biological particles in a liquid analyte material. The method comprises applying a volume of a liquid sample to an exposing domain from which exposing domain electromagnetic signals from the sample in the domain can pass to the exterior, and exposing, onto an array of active detection elements such as CCD-elements, a spatial representation of electromagnetic signals having passed from the domain, the representation being detectable as an intensity by individual active detection elements, under conditions permitting processing of the intensities detected by the array of detection elements during the exposure in such a manner that representations of electromagnetic signals from the biological particles are identified as distinct from representations of electromagnetic signals from background signals. The size of the volume of the liquid sample is sufficiently large to permit the assessment of the quantity and quality parameters to fulfill a predetermined requirement to the statistical quality of the assessment based on substantially one exposure.

公开(公告)号：US20060066851A1

公开(公告)日：2006-03-30

申请号：US11224600

申请日：2005-09-12

申请人： Lee Heineman

发明人： Lee Heineman

IPC分类号： G01N21/00

CPC分类号： G01N15/0227 ,  G01N15/1475 ,  G01N21/39 ,  G01N21/47 ,  G01N2015/025 ,  G01N2021/399

摘要： Computer-implemented methods and programs for organizing image data representing light scattered from one or more substantially spherical microparticles and the resulting data structures are disclosed. A digital representation of an image produced on an electronic image plane by light scattered from one or more substantially spherical microparticles at each of a predetermined number (Q) of illuminating wavelengths is created. For each of the N pixels in each image an associated Image Intensity Data Array containing Q values is created. In one embodiment the resulting data structure is an inclusive collection of Pixel Records from each pixel in the image. In a second embodiment a select set of S number of Image Intensity Data Arrays is chosen. Each Image Intensity Data Array in the select set has at least one intensity value that exceeds a predetermined analog threshold. A Pointer Array containing N values is also created. The Pointer Array correlates the position on the electronic image plane of the pixel associated with each Image Intensity Data Array in the select set with the order of selection of that data array into the select set.

摘要翻译： 公开了用于组织表示从一个或多个基本上为球形的微粒散射的光的图像数据的计算机实现的方法和程序以及所得到的数据结构。 产生在预定数量（Q）的照明波长的每一个上由从一个或多个基本上球形的微粒散射的光在电子图像平面上产生的图像的数字表示。 对于每个图像中的每个N个像素，创建包含Q值的相关图像强度数据阵列。 在一个实施例中，所得到的数据结构是来自图像中的每个像素的像素记录的包含性集合。 在第二实施例中，选择一组S个图像强度数据阵列。 选择集中的每个图像强度数据阵列具有至少一个超过预定模拟阈值的强度值。 还会创建一个包含N值的指针数组。 指针阵列将与选择集中的每个图像强度数据阵列相关联的像素的电子图像平面上的位置与该数据阵列的选择顺序相关联到选择集中。

公开(公告)号：US20040246483A1

公开(公告)日：2004-12-09

申请号：US10727832

申请日：2003-12-04

申请人： CHEMOMETEC A/S

发明人： Frans Ejner Rvan Hansen ,  Martin Glensbjerg ,  Borkur Arnvidarson ,  Jesper Myron Jeppesen

IPC分类号： G01N021/00

CPC分类号： G01N15/1459 ,  B01L3/5027 ,  G01N15/1463 ,  G01N21/31 ,  G01N21/59 ,  G01N21/6428 ,  G01N21/6458 ,  G01N21/76 ,  G01N33/04 ,  G01N2015/025 ,  G01N2015/1452 ,  G01N2015/1486 ,  G01N2021/5957 ,  G01N2021/6491

摘要： This invention relates to apparatuses for non-contact three-dimensional measurement of bodies and methods for determining a system of coordinates for measuring points on an apparatus for non-contact three-dimensional measurement of bodies. The apparatus and the method are characterized by particular simplicity and easy implementation. Advantageously, this makes the apparatus and method applicable in production sites for special workpieces. This opens up a wide and highly cost-efficient range of uses. Before the workpieces are measured, a system of coordinates for three-dimensional matching of the workpiece geometry is determined in a first measurement. A body with known dimensions of its edges or lines is placed on any position on the turntable and measured during one rotation using the triangulation sensor. The apparatus according to the invention is thus characterized by its minimal design. The low number of movements required, i.e. one translatory movement of the triangulation sensor and a rotational movement of the turntable, results in determining the outline of a body with a minimal error of measurement.

摘要翻译： 本发明涉及用于身体的非接触三维测量的装置和用于确定用于身体的非接触式三维测量的装置上的测量点的坐标系的方法。 该装置和方法的特征在于特别简单和容易实现。 有利地，这使得该装置和方法适用于特殊工件的生产现场。 这开辟了广泛和高性价比的使用范围。 在测量工件之前，在第一测量中确定工件几何形状的三维匹配的坐标系。 具有其边缘或线的已知尺寸的主体被放置在转台上的任何位置上，并且在使用三角测量传感器的一次旋转期间被测量。 因此，根据本发明的装置的特征在于其最小的设计。 所需的运动次数较少，即三角测量传感器的一个平移运动和转台的旋转运动导致以最小的测量误差来确定身体轮廓。

公开(公告)号：US20040190009A1

公开(公告)日：2004-09-30

申请号：US10792869

申请日：2004-03-05

发明人： Hidekazu Yoshizawa ,  Masaki Hayashi

IPC分类号： G01B011/28

CPC分类号： G01B11/0625 ,  G01N15/1456 ,  G01N2015/025 ,  G01N2015/1493

摘要： In a microcapsule having a wall of a refractive index n1, a thickness-determining apparatus comprises at least (i) a sensor 1 for detecting a light scattering intensity data I1 with respect to a microcapsule dispersed in a medium having a refractive index n1, and a light scattering intensity data I2 with respect to a microcapsule dispersed in a medium having a refractive index n2; (ii) a memory circuit 3 for storing a theoretical equation correlating a light scattering intensity characteristic with a particle size; and (iii) an arithmetic circuit 5 for calculating an inner diameter r1 and an outer diameter r2 from the theoretical equation based on the light scattering intensity data I1 and I2, and calculating a wall thickness. In such an apparatus, since the refractive index of the medium conforms to the refractive index of the wall, the inner diameter can be calculated by a simple theoretical equation, and the wall thickness can be conveniently or certainly determined without destroying the wall by cutting.

摘要翻译： 在具有折射率n1的壁的微胶囊中，厚度测定装置至少包括：（i）用于检测相对于分散在具有折射率n1的介质中的微胶囊的光散射强度数据I1的传感器1，以及 相对于分散在具有折射率n2的介质中的微胶囊的光散射强度数据I2; （ii）存储电路3，用于存储将光散射强度特性与粒度相关的理论方程; 以及（iii）运算电路5，用于根据光散射强度数据I1和I2从理论方程计算内径r1和外径r2，并计算壁厚。 在这种装置中，由于介质的折射率符合壁的折射率，所以可以通过简单的理论方程来计算内径，并且可以方便或肯定地确定壁厚，而不会通过切割破坏壁。

公开(公告)号：US20040046957A1

公开(公告)日：2004-03-11

申请号：US10622318

申请日：2003-07-18

发明人： Barry James Stagg

IPC分类号： G01N015/02

CPC分类号： G01N1/2258 ,  B82Y30/00 ,  C01P2004/64 ,  C01P2006/12 ,  C09C1/50 ,  G01N1/2202 ,  G01N15/0205 ,  G01N15/1456 ,  G01N15/1459 ,  G01N21/71 ,  G01N2001/2223 ,  G01N2001/2264 ,  G01N2001/227 ,  G01N2001/242 ,  G01N2015/0092 ,  G01N2015/025 ,  G01N2015/0693 ,  G01N2015/1493

摘要： Method for in-situ sampling and measuring particulate (e.g., carbon black) fineness in a process stream, such as in a carbon black reactor, comprising (a) sampling particles in-situ from a process stream, (b) adjusting the sample to conditions suitable for LII, (c) measuring the fineness using LII, and (d) correlating the LII fineness measurement with actual particle fineness. Method for in-situ sampling a particle-containing stream and measuring particle fineness using laser-induced incandescence (LII) comprising (a) sampling particles in-situ, (b) adjusting the sample to conditions suitable for LII, (c) measuring the adjusted sample using LII, and (d) correlating the LII measurements with actual particle fineness. Also included is a method of sampling and controlling a process based on the real-time, on-line, in-situ methods for sampling and measuring particles. Sampling can comprise drawing a sidestream from a source of the particles. Adjusting the sample to conditions suitable for LII can comprise diluting the sample or bringing the temperature of the sample to ambient conditions. Correlating may comprise using a correlation function determined by comparing LII measurements and laboratory fineness measurements for particle samples drawn at the same time.

摘要翻译： 用于原位取样和测量工艺流中的颗粒（例如，炭黑）细度的方法，例如在炭黑反应器中，包括（a）从工艺流原位取样颗粒，（b）将样品调整为 适用于LII的条件，（c）使用LII测量细度，和（d）将LII细度测量与实际颗粒细度相关联。 用于使用激光诱导白炽（LII）原位取样含粒子流并测量颗粒细度的方法，包括（a）原位取样颗粒，（b）将样品调节至适合于LII的条件，（c） 使用LII调整样本，（d）将LII测量与实际颗粒细度相关联。 还包括一种基于用于采样和测量粒子的实时在线现场方法对过程进行采样和控制的方法。 抽样可以包括从颗粒的来源画出侧流。 将样品调整到适合LII的条件可包括稀释样品或使样品的温度达到环境条件。 相关可以包括使用通过比较LII测量和同时绘制的颗粒样品的实验室细度测量确定的相关函数。

公开(公告)号：US20030020910A1

公开(公告)日：2003-01-30

申请号：US09906580

申请日：2001-07-13

发明人： Todd Peterson ,  Laurence Warden ,  Juan Yguerabide ,  Evangelina Yguerabide

IPC分类号： G01N021/00

CPC分类号： G01N15/1459 ,  G01N15/1463 ,  G01N15/1484 ,  G01N2015/025 ,  G01N2015/0288 ,  G01N2015/0693 ,  G01N2015/1486

摘要： The use of light scattering particles in the design, manufacturing, and quality control of microscale devices and process, and the analysis of solid substrate and porous substrate characteristics is described.

摘要翻译： 描述了在微尺度器件和工艺的设计，制造和质量控制中的光散射粒子的使用，以及固体衬底和多孔衬底特​​性的分析。

公开(公告)号：US20030020447A1

公开(公告)日：2003-01-30

申请号：US09917453

申请日：2001-07-27

发明人： Richard Lee Taylor ,  Min Zheng

IPC分类号： G01N027/00

CPC分类号： G01N15/12 ,  G01N2015/025 ,  G01N2015/1062

摘要： A method is disclosed which allows more accurate counting of particles where the sample has significant size variability between particles. The method uses flight time and wait time to obtain a corrected count of particles.

摘要翻译： 公开了一种方法，其允许对颗粒进行更精确的计数，其中样品在颗粒之间具有显着的尺寸变化。 该方法使用飞行时间和等待时间来获得校正的粒子数。

公开(公告)号：US5748311A

公开(公告)日：1998-05-05

申请号：US614937

申请日：1996-03-11

申请人： Oliver Hamann ,  Reinhard Ulrich

发明人： Oliver Hamann ,  Reinhard Ulrich

IPC分类号： G01N15/02 ,  G01N15/14 ,  G01N21/00

CPC分类号： G01N15/0205 ,  G01N2015/025 ,  G01N2015/0294 ,  G01N2015/145 ,  G01N2015/1497

摘要： The invention provides a method and a system for measuring geometric properties, such as diameter, shape and surface roughness of single rough particles by an optical method. The particle may be immersed in a gaseous or liquid fluid. A volume of the fluid, containing the particles to be measured, is illuminated by a beam of coherent electromagnetic radiation, resulting in a distribution of scattered radiation with a speckle structure. This distribution is detected with a one-dimensional or two-dimensional image detector. An autocorrelation function RI(r) of the detected intensity distribution is calculated, and from the position .delta.r of its first zero the diameter d.sub.P of the scattering particle is evaluated based on I, the wavelength of the electromagnetic radiation, and Z.sub.0, the distance from the particle to the detector. The system to perform this method comprises a radiation source, which is preferably a laser, to illuminate a measuring volume, and an array or matrix detector arranged to receive the backscattered light. The detected intensity distribution is converted to binary data and a signal processing unit calculates the autocorrelation function of the detected intensity distribution to yield the particle size. In a preferred embodiment of the invention, the radiation scattered from a particle is relayed to the detector by an optical system comprising a set of lenses, a polarizer and a pinhole. The surface roughness of the particle under investigation is estimated from the contrast of the measured intensity distribution. The shape of the particle follows from an evaluation of the calculated diameter values along a set of angular directions .phi.=0 . . . .pi..

摘要翻译： 本发明提供一种用于通过光学方法测量单个粗糙颗粒的几何性质，例如直径，形状和表面粗糙度的方法和系统。 颗粒可以浸入气体或液体流体中。 含有待测量颗粒的流体体积被相干电磁辐射束照射，导致具有斑点结构的散射辐射的分布。 该分布用一维或二维图像检测器检测。 计算检测强度分布的自相关函数RI（r），从其第一零点的位置delta r，基于I，电磁辐射的波长和Z0来评估散射粒子的直径dP，距离 从粒子到检测器。 执行该方法的系统包括辐射源（其优选地是激光器）照射测量体积，以及布置成接收反向散射光的阵列或矩阵检测器。 检测到的强度分布被转换为二进制数据，信号处理单元计算检测到的强度分布的自相关函数以产生粒子大小。 在本发明的优选实施例中，从颗粒散射的辐射通过包括一组透镜，偏振器和针孔的光学系统中继到检测器。 根据测量的强度分布的对比度估算研究中的颗粒的表面粗糙度。 粒子的形状遵循沿着一组角度方向phi = 0计算的直径值的评估。 。 。 pi。

公开(公告)号：US11774339B2

公开(公告)日：2023-10-03

申请号：US17215691

申请日：2021-03-29

申请人： X ENERGY, LLC

发明人： Nicholas Linneen

IPC分类号： G01N15/02 ,  G01N11/12 ,  G01N11/00

CPC分类号： G01N15/0205 ,  G01N11/12 ,  G01N2011/008 ,  G01N2015/025

摘要： Metal oxide gel particles, may be prepared with a desired particle size, by preparing a low-temperature aqueous metal nitrate solution containing hexamethylene tetramine as a feed solution; and causing the feed solution to flow through a first tube and exit the first tube as a first stream at a first flow rate, so as to contact a high-temperature nonaqueous drive fluid. The drive fluid flows through a second tube at a second flow rate. Shear between the first stream and the drive fluid breaks the first stream into particles of the metal nitrate solution, and decomposition of hexamethylene tetramine converts metal nitrate solution particles into metal oxide gel particles. A metal oxide gel particle size is measured optically, using a sensor device directed at a flow of metal oxide gel particles within the stream of drive fluid. The sensor device measures transmission of light absorbed by either the metal oxide gel particles or the drive fluid, so that transmission of light through the drive fluid changes for a period of time as a metal oxide gel particle passes the optical sensor. If a measured particle size is not about equal to a desired particle size, the particle size may be corrected by adjusting a ratio of the first flow rate to a total flow rate, where the total flow rate is the sum of the first and second flow rates.