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    METHOD OF NONINVASIVE OPTICAL MEASUREMENT OF PROPERTIES OF FREE-FLOWING BLOOD
    13.
    发明申请
    METHOD OF NONINVASIVE OPTICAL MEASUREMENT OF PROPERTIES OF FREE-FLOWING BLOOD 审中-公开

    公开(公告)号：US20170181633A1

    公开(公告)日：2017-06-29

    申请号：US15310980

    申请日：2015-05-19

    申请人： NIRLUS Engineering AG

    发明人： Vera HERRMANN

    IPC分类号： A61B5/00 ,  A61B8/08 ,  G01N21/47 ,  A61B5/1455

    CPC分类号： A61B5/0048 ,  A61B5/0097 ,  A61B5/01 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/14552 ,  A61B5/7228 ,  A61B8/085 ,  A61B8/4416 ,  A61B8/488 ,  A61B2562/0233 ,  G01N21/4795 ,  G01N2021/4709

    摘要： The invention relates to a method of the noninvasive optical in-vivo measurement of properties of flowing blood in a blood vessel within a body, for example for determining the concentration of blood constituents, wherein the body is irradiated with ultrasound radiation at an ultrasound frequency (fUS) in order to label a blood vessel, the body with the blood vessel is illuminated with light with at least one light wavelength and the back-scattered light is detected with a detector, the light component backscattered by the body outside of the blood vessel is modulated by a frequency (fMG) that corresponds to the frequency (fUS) of the ultrasound radiation, and the light component backscattered inside the blood vessel is modulated due to the Doppler effect in flowing blood with a frequency (fMB) that is shifted by the Doppler shift (fD) with respect to the frequency (fUS) of the ultrasound radiation, and an evaluation device extracts the signal component modulated by the shifted frequency (fMB) from the detector signal measured at the detector.

    Method and instrumentation for determining a physical property of a particle
    14.
    发明授权
    Method and instrumentation for determining a physical property of a particle 有权
    用于确定颗粒物理性质的方法和仪器

    公开(公告)号：US09594011B2

    公开(公告)日：2017-03-14

    申请号：US12124767

    申请日：2008-05-21

    申请人： William D. Herzog

    发明人： William D. Herzog

    IPC分类号： G01N33/50 ,  G01N15/14 ,  G01N21/53 ,  G01N21/35 ,  G01N21/47 ,  G01N21/3577

    CPC分类号： G01N15/1456 ,  G01N21/35 ,  G01N21/3577 ,  G01N21/53 ,  G01N2021/4707 ,  G01N2021/4709 ,  G01N2021/4726

    摘要： Physical property determination of a particle or classification of the particle as a function of the physical property by evaluating scattered light profile from a single particle is disclosed. The particle may include chemical structures that vibrate as a function of a physical property of the particle. The physical property may include an absorptive property of the particle or a chemical composition. From a detected scattered light spectrum, at least two anomalous dispersive regions may be identified. The physical property of the particle may be determined as a function of the at least two regions. A system employing the physical property determination can achieve sensitivities useful for low particle density applications such as detection for biological and chemical agents.

    摘要翻译： 公开了通过从单个颗粒评估散射光轮廓，粒子的物理性质或颗粒的分类作为物理性质的函数。 颗粒可以包括作为颗粒的物理性质的函数振动的化学结构。 物理性质可以包括颗粒的吸收性质或化学组成。 从检测到的散射光谱中，可以识别至少两个异常色散区域。 颗粒的物理性质可以确定为至少两个区域的函数。 采用物理性质测定的系统可以实现用于低颗粒密度应用的灵敏度，例如生物和化学试剂的检测。

    DYNAMIC LIGHT SCATTERING BASED MICRORHEOLOGY OF COMPLEX FLUIDS WITH IMPROVED SINGLE-SCATTERING MODE DETECTION
    16.
    发明申请
    DYNAMIC LIGHT SCATTERING BASED MICRORHEOLOGY OF COMPLEX FLUIDS WITH IMPROVED SINGLE-SCATTERING MODE DETECTION 审中-公开
    具有改进的单扫描模式检测的复合流体的基于动态光散射的微观学

    公开(公告)号：US20170003220A1

    公开(公告)日：2017-01-05

    申请号：US15013084

    申请日：2016-02-02

    申请人： Samiul Amin ,  Carlos Alberto Rega

    发明人： Samiul Amin ,  Carlos Alberto Rega

    IPC分类号： G01N21/51 ,  G01N15/14 ,  G01N11/00 ,  G01N21/03

    CPC分类号： G01N21/51 ,  G01N11/00 ,  G01N15/1436 ,  G01N21/03 ,  G01N2011/008 ,  G01N2021/0346 ,  G01N2021/4707 ,  G01N2021/4709 ,  G01N2021/513 ,  G01N2201/08

    摘要： A fluid characterization measuring instrument is disclosed that comprises a sample vessel for a bulk complex sample fluid having a capacity that is substantially larger than a domain size of the complex sample fluid and that is sufficiently large to cause bulk scattering effects to substantially exceed surface effects for the complex fluid sample, a coherent light source positioned to illuminate the bulk complex sample fluid in the sample vessel and a first fibre having a first end positioned to receive backscattered light from the sample after it has interacted with the sample. The first fibre can also be positioned close enough to an optical axis of the coherent light source and to the sample vessel to substantially decrease a contribution of multiply scattered light in the backscattered light. The instrument can further comprise a first photon-counting detector positioned to receive the backscattered light from a second end of the fibre, correlation logic responsive to the first photon-counting detector and single-scattering fluid property analysis logic responsive to the correlation logic and operative to derive at least one fluid property for the sample fluid.

    摘要翻译： 公开了一种流体表征测量仪器，其包括用于大体积复合物样品流体的样品容器，其容量基本上大于复杂样品流体的结构域尺寸，并且足够大以引起体积散射效应，从而基本上超过表面效应 所述复杂流体样品，定位成照射所述样品容器中的本体复合物样品流体的相干光源和具有第一端的第一光纤，所述第一光纤定位成在与所述样品相互作用后接收来自所述样品的反向散射光。 第一光纤还可以被定位成足够靠近相干光源的光轴并且到达样品容器，以显着降低多个散射光在后向散射光中的贡献。 仪器还可以包括第一光子计数检测器，其定位成从光纤的第二端接收反向散射光，响应于第一光子计数检测器的相关逻辑和响应于相关逻辑和操作的单散射流体属性分析逻辑 以产生用于样品流体的至少一种流体性质。

    Systems and Methods for Detecting Gases, Airborne Compounds, and Other Particulates
    19.
    发明申请
    Systems and Methods for Detecting Gases, Airborne Compounds, and Other Particulates 有权
    检测气体，空气化合物和其他微粒的系统和方法

    公开(公告)号：US20160274025A1

    公开(公告)日：2016-09-22

    申请号：US15074840

    申请日：2016-03-18

    申请人： SMS Sensors Incorporated

    发明人： Richard J. Skibo ,  Karin L. Fisher

    IPC分类号： G01N21/39 ,  G06N99/00

    CPC分类号： G01N21/39 ,  G01N21/31 ,  G01N21/3504 ,  G01N21/538 ,  G01N2021/1793 ,  G01N2021/1795 ,  G01N2021/394 ,  G01N2021/399 ,  G01N2021/4709 ,  G01N2201/10 ,  G01S7/4802 ,  G01S17/88 ,  G01S17/95 ,  G06N99/005 ,  Y02A90/19

    摘要： Systems and methods for detecting gases, airborne compounds, and other particulates, are provided. The system detects materials of interest, including but not limited to, volatile organic compounds, aerosols, particulates, and biological and other pathogens in a three dimensional volume over an area of interest. The system detects the concentration of analytes of interest in the presence of atmospheric contaminants. Data points form a three-dimensional “point cloud” to which particle swarm optimization and feature extraction algorithms are applied, providing leak detection, mapping of chemical plumes, and short-term and long-term flux measurements, among other functions.

    摘要翻译： 提供了用于检测气体，空气传播的化合物和其它颗粒物的系统和方法。 该系统检测感兴趣的材料，包括但不限于挥发性有机化合物，气溶胶，颗粒以及在感兴趣区域上的三维体积中的生物和其它病原体。 该系统在大气污染物的存在下检测感兴趣的分析物的浓度。 数据点形成三维“点云”，应用粒子群优化和特征提取算法，提供泄漏检测，化学羽流映射，短期和长期通量测量等功能。

    IMPROVEMENTS RELATING TO PARTICLE CHARACTERISATION
    20.
    发明申请
    IMPROVEMENTS RELATING TO PARTICLE CHARACTERISATION 审中-公开
    关于颗粒特征的改进

    公开(公告)号：US20160252443A1

    公开(公告)日：2016-09-01

    申请号：US15032289

    申请日：2014-11-04

    申请人： MALVERN INSTRUMENTS LIMITED

    发明人： David Spriggs

    IPC分类号： G01N15/02 ,  G01N21/51

    CPC分类号： G01N15/0205 ,  G01N15/0211 ,  G01N15/1456 ,  G01N21/51 ,  G01N2021/4707 ,  G01N2021/4709 ,  G01N2021/4711 ,  G02B3/02

    摘要： A particle characterisation apparatus is disclosed comprising: a light source; a sample cell; a collecting lens and a detector. The light source is operable to illuminate a sample comprising dispersed particles within the sample cell with a light beam along a light beam axis. The light beam axis passes through a first wall of the sample cell, through the sample, and through a second wall of the sample cell, so as to produce scattered light by interactions with the sample. The detector is configured to detect light scattered from the sample. The second wall of the sample cell comprises a lens with a convex external surface through which the light beam axis passes. The collecting lens is arranged to collect and focus scattered light leaving the sample cell onto the detector, and comprises an aspheric surface.

    摘要翻译： 公开了一种粒子表征装置，包括：光源; 样品池; 收集透镜和检测器。 光源可操作以用沿着光束轴的光束照射包含样品池内的分散颗粒的样品。 光束轴穿过样品池的第一壁，通过样品，并通过样品池的第二壁，以便通过与样品的相互作用产生散射光。 检测器被配置为检测从样品散射的光。 样品池的第二壁包括具有凸出的外表面的透镜，光束轴通过该透镜。 收集透镜被布置成将离开样品池的散射光聚集并聚焦到检测器上，并且包括非球面。