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公开(公告)号：US09932233B2
公开(公告)日：2018-04-03
申请号：US14766157
申请日：2014-02-06
Inventor： Kevin William Powers , Jiaqing Zhou , Parvesh Sharma , Spyros A. Svoronos , Brij M. Moudgil , Gary Wayne Scheiffele , Ajoy K. Saha , Paul Louis Carpinone
CPC classification number: C01B19/007 , B01J4/008 , B01J19/0033 , B01J19/004 , B01J2219/00054 , B01J2219/00162 , B01J2219/00186 , B22F9/24 , B82Y20/00 , C01B33/12 , C01P2002/72 , C01P2002/84 , C01P2004/04 , C01P2004/64 , C01P2004/80 , C22B11/04 , H01B1/02 , Y10S977/774
Abstract: A continuous reaction system (CRS) allows a method to prepare quantum dots (QDs) in a continuous manner with high precision. The CRS pumps a plurality of reagent fluids into one or more mixing sites to form a reaction fluid that is carried through a heating chamber at elevated pressures to carry out hydrothermal growth of the QDs. The pumps and heating chamber are controlled with a high precision by employing a detector downstream of the heating chamber to provide a signal that is dependent on the composition and size of the QDs. The signal is provided to a signal processor that provides a signal that control the flow rates and temperature parameters in the system. The QDs produced in this manner are consistent in size and composition and can be of a single semiconductor composition or can be core-shell QDs with a shell semiconductor formed on a core semiconductor.
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公开(公告)号：US09907833B2
公开(公告)日：2018-03-06
申请号：US14340858
申请日：2014-07-25
Inventor： Kirk P. Conrad
CPC classification number: A61K38/2221 , C12Q1/6876 , C12Q2600/106 , C12Q2600/158 , C12Q2600/16 , G01N33/6893 , G01N2800/368
Abstract: The subject application relates to methods for treating a placental syndrome, wherein relaxin is administered during the late secretory/luteal (LS) phase of the menstrual cycle in women who have a propensity for developing the placental syndrome. In certain embodiments, administration of relaxin continues beyond the LS phase and into pregnancy.
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公开(公告)号：US20180051299A9
公开(公告)日：2018-02-22
申请号：US14994477
申请日：2016-01-13
Inventor： Barry John Byrne , Darin J. Falk , Christina Pacak , Lara Robert Deruisseau , Cathryn Mah , David D. Fuller
CPC classification number: C12N15/86 , A61K9/0019 , A61K45/06 , A61K48/0058 , A61K48/0075 , C12N7/00 , C12N2710/16644 , C12N2750/14143 , C12N2750/14145 , C12N2750/14151 , C12N2810/6027 , C12N2830/008 , C12Y302/0102
Abstract: The present invention provides compositions and methods of use pertaining to rAAV-mediated delivery of therapeutically effective molecules for treatment of diseases such as Pompe disease. These compositions in combination with various routes and methods of administration result in targeted expression of therapeutic molecules in specific organs, tissues and cells.
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公开(公告)号：US20180038873A1
公开(公告)日：2018-02-08
申请号：US15549166
申请日：2016-02-05
Inventor： SADASIVAN VIDYASAGAR , PAUL OKUNIEFF , ANAND VIDYASAGAR
IPC: G01N33/68 , G01N33/567 , C12Q1/68
CPC classification number: G01N33/6893 , C12Q1/6876 , C12Q1/6883 , C12Q2600/158 , G01N33/566 , G01N33/567 , G01N2800/40
Abstract: Embodiments of the present invention are directed to the use of NHE3 as an early biomarker for radiation biodosimetry. In other embodiments, the present invention relates to the use of NHE3 as a biomarker for determining the absorbed radiation dose in a subject who has been exposed to a known or unknown dose of ionizing radiation. Further embodiments relate to the use of NHE3 as a biomarker for determining effectiveness of a therapy for reducing radiation toxicity. Advantageously, the diagnostic and prognostic assays of the present invention are rapid, sensitive, and non-invasive, rendering it useful in civilian and military industries.
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公开(公告)号：US20180037466A1
公开(公告)日：2018-02-08
申请号：US15317265
申请日：2016-04-20
Inventor： James Klausner , Kelvin Fnu Randhir , Nicholas AuYueng , Like Li , Nathan Rhodes , Amey Anand Barde , Renwei Mei , David Worthington Hahn
CPC classification number: C01F11/06 , C01B15/04 , C01B32/50 , C01F11/187 , F03G6/003 , F03G6/06 , F28F13/18 , Y02E10/46 , Y02P20/129 , Y02P20/134
Abstract: Disclosed herein is a method comprising heating a strontium-containing compound using radiation in a first reactor; decomposing the strontium-containing compound into an oxide and carbon dioxide as a result of heat generated by the exposure to the radiation; reacting the oxide and the carbon dioxide in a second reactor; where the oxide and carbon dioxide react to produce heat; heating a working fluid using the heat produced in the second reactor; and driving a turbine with the heated working fluid to generate energy. Disclosed herein too is a composition comprising strontium carbonate; and strontium zirconate; where the mass ratio of strontium carbonate to strontium zirconate 2:8 to 8:2.
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Patent Agency Ranking
236.发明申请公开(公告)号：US20180033511A1
公开(公告)日：2018-02-01
申请号：US15709782
申请日：2017-09-20
Inventor： JUAN CLAUDIO NINO , PAUL M. JOHNS , JAMES EDWARD BACIAK
Abstract: Embodiments of the present disclosure relate to compositions including a doped material, batteries including the composition, photovoltaic devices including the battery, and the like.
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公开(公告)号：US20180019491A1
公开(公告)日：2018-01-18
申请号：US15669155
申请日：2017-08-04
Inventor： Andrew Gabriel Rinzler , Rajib Kumar Das , Yan Wang , Hai-Ping Cheng
CPC classification number: H01M8/0656 , C25B11/12 , H01M4/8615 , H01M4/8825 , H01M4/90 , H01M4/96 , H01M8/0234 , H01M8/0239 , H01M8/186 , H01M2250/10 , H01M2250/402 , Y02B90/12 , Y02B90/14 , Y02E60/528 , Y02P20/133
Abstract: An electrode comprises an acid treated, cathodically cycled carbon-comprising film or body. The carbon consists of single walled nanotubes (SWNTs), pyrolytic graphite, microcrystalline graphitic, any carbon that consists of more than 99% sp2 hybridized carbons, or any combination thereof. The electrode can be used in an electrochemical device functioning as an electrolyser for evolution of hydrogen or as a fuel cell for oxidation of hydrogen. The electrochemical device can be coupled as a secondary energy generator into a system with a primary energy generator that naturally undergoes generation fluctuations. During periods of high energy output, the primary source can power the electrochemical device to store energy as hydrogen, which can be consumed to generate electricity as the secondary source during low energy output by the primary source. Solar cells, wind turbines and water turbines can act as the primary energy source.
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公开(公告)号：US20180017569A1
公开(公告)日：2018-01-18
申请号：US15665726
申请日：2017-08-01
Inventor： Richard J. Melker , Donn Michael Dennis , Christopher D. Batich , Mark S. Gold
CPC classification number: G01N33/58 , A61B5/083 , A61B5/411 , A61B5/4833 , A61K49/0004 , A61K51/1206 , G01N2458/15 , Y10T436/22
Abstract: The present invention relates to the detection of markers in exhaled breath, wherein the detection of the presence or absence of the marker(s) in exhaled breath is used to assess various clinical data, including patient adherence in taking the medication and patient enzymatic (metabolic) competence in metabolizing the medication. An embodiment of the invention comprises a parent therapeutic agent labeled with a marker, where upon metabolism (e.g., via enzymatic action) of the therapeutic agent, the marker becomes volatile or semi-volatile and is present in the breath. In certain related embodiments, the marker contain a deuterium label, which is also present in the breath upon metabolism of the therapeutic agent. In another embodiment of the invention, the therapeutic agent is associated with a taggant (that may be either labeled or unlabeled with deuterium), which in turn will generate a marker in the breath that is easily measurable.
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公开(公告)号：US20180008737A1
公开(公告)日：2018-01-11
申请号：US15698795
申请日：2017-09-08
Inventor： Subrata ROY , Karl ZAWOY
CPC classification number: A61L2/14 , A61L2/24 , A61L2202/11 , A61L2202/24
Abstract: Embodiments of the invention relate to a method and apparatus for self-sterilizing a surface or other portion of the apparatus and/or sterilizing other objects. Embodiments can utilize self-generated and/or remotely controlled plasma fields for the purpose of self-sterilization and/or sterilization of another object. Embodiments of the invention can have broad applications in procedures and equipment requiring the sterility of devices used for medical procedures, decontamination procedures, drug delivery, sterility of consumer products, and sterility of food preparation equipment and tools.
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公开(公告)号：US20180008155A1
公开(公告)日：2018-01-11
申请号：US15651697
申请日：2017-07-17
Inventor： Richard J. Melker , Neil Euliano , Brian Fuerhlein
IPC: A61B5/0295 , A61B5/02 , A61B5/1455 , A61M16/06 , A61B5/00 , A61B5/026 , A61B5/024
CPC classification number: A61B5/0295 , A61B5/02 , A61B5/02416 , A61B5/0261 , A61B5/14552 , A61B5/6803 , A61B5/6815 , A61B5/6817 , A61B5/6819 , A61B5/6838 , A61M16/0051 , A61M16/06 , A61M16/0627 , A61M16/0683 , A61M2230/205 , A61M2230/432
Abstract: Provided according to embodiments of the present invention are methods of monitoring individuals that include securing a photoplethysmography probe to at least one of a pre-auricular region and a post-auricular region of the individual and obtaining photoplethysmography signals from the photoplethysmography probe. Photoplethysmography probes and helmets related to such methods are also described herein.
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