公开(公告)号：US20050100987A1

公开(公告)日：2005-05-12

申请号：US10960905

申请日：2004-10-07

Applicant: Thomas Evans ,  Ming Xu ,  Shaorong Chong

Inventor： Thomas Evans ,  Ming Xu ,  Shaorong Chong

IPC: C07K19/00 ,  C12N9/00 ,  C12N9/02 ,  C12N9/14 ,  C12N15/10 ,  C12N15/62 ,  C12P21/02 ,  C12P21/06 ,  C07H21/04 ,  C12N1/18 ,  C12N5/06 ,  C12N15/74

CPC classification number: C12N9/0093 ,  C07K19/00 ,  C07K2319/00 ,  C07K2319/20 ,  C07K2319/24 ,  C07K2319/55 ,  C07K2319/92 ,  C12N9/14 ,  C12N9/93 ,  C12N15/10 ,  C12N15/62 ,  C12P21/02

Abstract: A method for the ligation of expressed proteins which utilizes inteins, for example the RIR1 intein from Methanobacterium thermotrophicum , is provided. Constructs of the Mth RIR1 intein in which either the C-terminal asparagine or N-terminal cysteine of the intein are replaced with alanine enable the facile isolation of a protein with a specified N-terminal, for example, cysteine for use in the fusion of two or more expressed proteins. The method involves the steps of generating a C-terminal thioester-tagged target protein and a second target protein having a specified N-terminal via inteins, such as the modified Mth RIR1 intein, and ligating these proteins. A similar method for producing a cyclic or polymerized protein is provided. Modified inteins engineered to cleave at their C-terminus or N-terminus, respectively, and DNA and plasmids encoding these modified inteins are also provided.

Abstract translation: 提供了利用内含肽表达的蛋白质的连接方法，例如来自热嗜热杆菌的RIR1内含肽。 第三RIR1内含肽的构建体，其中内含肽的C-末端天门冬酰胺或N-末端半胱氨酸被丙氨酸取代，能够容易地分离具有指定N-末端的蛋白质，例如半胱氨酸用于融合 两种或更多表达的蛋白质。 该方法包括产生C-末端硫酯标记的靶蛋白和通过内含肽（例如经修饰的第M RIR1内含肽）具有特定N-末端的第二靶蛋白并连接这些蛋白质的步骤。 提供了用于生产环状或聚合蛋白质的类似方法。 还提供了修饰的内含肽，分别设计用于在其C末端或N末端切割，以及编码这些修饰的内含肽的DNA和质粒。

公开(公告)号：US06879754B2

公开(公告)日：2005-04-12

申请号：US10188955

申请日：2002-07-03

Applicant: Jianjun Zhang ,  Peiching Ling ,  Jinliang Chen ,  Ming Xu

Inventor： Jianjun Zhang ,  Peiching Ling ,  Jinliang Chen ,  Ming Xu

IPC: A61K31/40 ,  A61K31/44 ,  A61K31/63 ,  C07C311/39 ,  C07C311/49 ,  C07D209/14 ,  G02B6/12 ,  G02B6/124 ,  G02B6/125 ,  G02B6/34 ,  G02B6/35 ,  H04Q11/00

CPC classification number: G02B6/3536 ,  A61K31/40 ,  A61K31/44 ,  A61K31/63 ,  C07C311/39 ,  C07C311/49 ,  C07D209/14 ,  G02B6/12004 ,  G02B6/12007 ,  G02B6/124 ,  G02B6/125 ,  G02B6/29323 ,  G02B6/3502 ,  G02B6/355 ,  G02B6/3566 ,  G02B6/357 ,  G02B2006/12107 ,  G02B2006/12145 ,  H04Q11/0005 ,  H04Q2011/0016 ,  H04Q2011/0024 ,  H04Q2011/0032 ,  H04Q2011/0058

Abstract: The present invention discloses a drop-before-add optical routing and switching system. The drop-before-add optical routing and switching system includes an input waveguide for carrying a multiplexed optical signal comprising optical signals transmitted over a plurality of wavelength channels represented by λ1, λ2, λ3, . . . , λN−1 and λN, where N is a positive integer wherein the input waveguide extending over a first direction. The drop-before-add optical routing and switching system further includes a plurality of second direction waveguides extending over a second direction and intersecting at N intersections with the input waveguide. The drop-before-add optical routing and switching system further includes a plurality of wavelength selective grating switches each disposed on one of the N intersections for selectively transmitting an optical signal of a selected wavelength into an associated one of the second direction waveguide.

Abstract translation: 本发明公开了一种前置添加光路由和交换系统。 后添加光路由和交换系统包括用于承载复用光信号的输入波导，该多路复用光信号包括由λ1，λ2，λ3表示的多个波长信道上发送的光信号。 。 。 ，λN-1和λN，其中N是正整数，其中输入波导在第一方向上延伸。 后添加光路由和交换系统还包括多个第二方向波导，其在第二方向上延伸并且在与输入波导的N个交叉处相交。 前置添加光路由和切换系统还包括多个波长选择性光栅开关，每个波长选择光栅开关各自设置在N个相交中的一个上，用于选择性地将所选波长的光信号传输到第二方向波导中的相关联的一个。

公开(公告)号：US06868348B1

公开(公告)日：2005-03-15

申请号：US09430077

申请日：1999-10-29

Applicant: Donn V. Stoutenburg ,  Ming Xu

Inventor： Donn V. Stoutenburg ,  Ming Xu

IPC: G01M7/02 ,  G01F17/00 ,  G01F23/00

CPC classification number: G01M7/025 ,  G01N2291/044

Abstract: A data collector having a digital signal processing circuit that receives a digitized vibration signal, and performs processing steps to isolate high frequency pulses in the digitized vibration signal and quantify energy content of those pulses by detecting a peak negative value of the digitized peak-to-peak amplitude of the received vibration signal, and then using this peak negative value to compute a maximum peak-to-peak value of the received vibration signal. Periodically, the maximum peak-to-peak value and peak negative value are reduced in magnitude by a decay factor, such that the peak negative value and maximum peak-to-peak value decay over time. The decay factors used in computing the maximum peak-to-peak value and peak negative value are determined by the digital signal processing circuit and may be readily changed. As a consequence, high frequency processing performed by the digital signal processing circuit may be readily adapted to the particular frequency characteristics of the machine being analyzed for predictive maintenance, without modification of the analog circuitry of the data collector. The resulting maximum peak-to-peak value comprises a peak-detected digital output signal that may be stored and/or displayed to a user as a reflection of the high frequency content of the vibration signal, or frequency transformed for storage and/or display to a user.

Abstract translation: 数据采集​​器具有接收数字化振动信号的数字信号处理电路，并且执行处理步骤，以隔离数字化振动信号中的高频脉冲，并且通过检测数字化峰 - 峰信号的峰值负值来量化这些脉冲的能量含量， 接收到的振动信号的峰值振幅，然后使用该峰值负值来计算接收振动信号的最大峰 - 峰值。 周期性地，最大峰 - 峰值和峰值负值以幅度减小衰减因子，使得峰值负值和最大峰 - 峰值随时间衰减。 用于计算最大峰 - 峰值和峰值负值的衰减因子由数字信号处理电路确定，并且可以容易地改变。 因此，数字信号处理电路执行的高频处理可以容易地适应于被分析用于预测维护的机器的特定频率特性，而不改变数据采集器的模拟电路。 所产生的最大峰 - 峰值包括峰值检测数字输出信号，其可以被存储和/或显示给用户，作为振动信号的高频内容的反映，或变换为用于存储和/或显示的频率 给用户

公开(公告)号：US06781853B2

公开(公告)日：2004-08-24

申请号：US10269952

申请日：2002-10-15

Applicant: Ming Xu ,  Fred C. Lee

Inventor： Ming Xu ,  Fred C. Lee

IPC: H02M3335

CPC classification number: H02M3/33592 ,  Y02B70/1475

Abstract: A method and apparatus for preventing current flow through the integral body diode of an electronic switch (e.g. MOSFET) in the secondary circuit of a synchronous rectifier. In a conventional synchronous rectifier, body diode current 31a 31b occurs during dead times 32a 32b. In the present invention, current steering pulses 40 are applied to the secondary circuit to oppose freewheeling current flow through the integral body diode. The current steering pulses produce a current that maintains the body diode in a reverse-biased state. Also, body diode current 31a 31b is prevented in the invention by short-circuiting a primary winding 19 of a transformer. The present invention prevents body diode conduction energy losses, as well as reverse recovery losses. The present invention is applicable to many different kinds of synchronous rectifiers such as current doubling rectifiers, center-tapped rectifiers, full bridge rectifiers.

Abstract translation: 一种用于防止电流通过同步整流器的次级电路中的电子开关（例如MOSFET）的整体二极管的方法和装置。 在传统的同步整流器中，体二极管电流31a 31b在死区时间32a 32b期间发生。 在本发明中，电流转向脉冲40被施加到次级电路以抵抗通过整体二极管的续流电流。 当前的转向脉冲产生将体二极管保持在反向偏置状态的电流。 此外，本发明通过使变压器的初级绕组19短路来防止体二极管电流31a 31b。 本发明防止体二极管传导能量损失以及反向恢复损耗。 本发明可应用于许多不同种类的同步整流器，例如电流倍增整流器，中心抽头整流器，全桥整流器。

公开(公告)号：US06320563B1

公开(公告)日：2001-11-20

申请号：US09235082

申请日：1999-01-21

Applicant: Deng-Ke Yang ,  Ming Xu

Inventor： Deng-Ke Yang ,  Ming Xu

IPC: G09G336

CPC classification number: G09G3/3629 ,  G09G2300/0486

Abstract: A dual frequency cholesteric display includes a pair of opposed substrates, wherein one of the substrates has a first plurality of electrodes facing a second plurality of electrodes on the other substrate. A dual frequency bistable cholesteric liquid crystal material is disposed between the substrates, wherein the material and the intersection of the first and second plurality of electrodes forms a plurality of pixels. By selectively applying high and low frequency voltages to the plurality of pixels, the high frequency voltage causes the material to exhibit one texture and the low frequency voltage causes the material to exhibit another texture. By adjusting a voltage amplitude value for each high and low frequency causes each pixel to exhibit a desired reflectance.

Abstract translation: 双频胆甾型显示器包括一对相对的基板，其中一个基板具有面对另一基板上的第二多个电极的第一多个电极。 双频双稳态胆甾型液晶材料设置在基板之间，其中第一和第二多个电极的材料和交点形成多个像素。 通过选择性地将高频和低频电压施加到多个像素，高频电压使材料呈现出一个纹理，并且低频电压导致材料呈现另外的纹理。 通过调整每个高频和低频的电压振幅值使每个像素呈现所需的反射率。

公开(公告)号：US6103041A

公开(公告)日：2000-08-15

申请号：US374144

申请日：1999-08-12

Applicant: Barbara Wagner ,  Ming Xu ,  Kimberlee Thompson

Inventor： Barbara Wagner ,  Ming Xu ,  Kimberlee Thompson

IPC: B41M5/382 ,  B32B37/00 ,  B41M1/26 ,  B41M5/025 ,  B41M5/385 ,  B41M5/392 ,  B41M7/00 ,  B44C1/17 ,  C09D11/02 ,  D06P1/38 ,  D06P1/52 ,  D06P5/00 ,  D06P5/20 ,  D06P5/24 ,  D06Q1/10 ,  D06Q1/12 ,  B44C1/165 ,  B32B27/14 ,  B32B31/00 ,  B41M31/00 ,  C09J31/00

CPC classification number: D06Q1/12 ,  B41M5/0023 ,  B41M5/0256 ,  B41M5/392 ,  B41M7/009 ,  B44C1/1716 ,  C09D11/03 ,  D06P1/5285 ,  D06P5/001 ,  D06P5/007 ,  D06P5/2077 ,  D06Q1/10 ,  D06P1/38

Abstract: A method of printing an ink or meltable ink layer which comprises dyes or pigments or other colorants. The ink or ink melt layer comprises compounds with functional groups capable of reacting with active hydrogen, and compounds with functional groups containing active hydrogen, or functional groups capable of conversion to active hydrogen containing groups. An image is printed onto a substrate, at a relatively low temperature, so that the ink is not activated during the process of printing on to the medium. The image is subsequently transferred or permanently fixed on the substrate by the application of heat and pressure, which activates the ink, and bonds the colorant to the substrate. The reactive compounds may be blocked with blocking agents which are removed by the application of heat or other energy during activation of the ink.

Abstract translation: 印刷油墨或可熔化油墨层的方法，其包含染料或颜料或其它着色剂。 油墨或油墨熔融层包括具有能够与活性氢反应的官能团的化合物，以及含有活性氢的官能团的化合物或能够转化为含活性氢基团的官能团。 在相对较低的温度下将图像印刷到基材上，使得在印刷到介质的过程中油墨不被活化。 随后通过施加热和压力将图像转移或永久地固定在基底上，其激活墨水，并将着色剂粘合到基底上。 活性化合物可以用封闭剂封闭，封闭剂在油墨活化期间通过施加热或其它能量除去。

公开(公告)号：US5830263A

公开(公告)日：1998-11-03

申请号：US807964

申请日：1997-02-28

Applicant: Nathan Hale ,  Ming Xu

Inventor： Nathan Hale ,  Ming Xu

IPC: B41F16/02 ,  B41J2/01 ,  B41J2/315 ,  B41J2/325 ,  B41J3/407 ,  B41M5/025 ,  B41M5/035 ,  B41M5/382 ,  B44C1/17 ,  C09D11/00 ,  C09D11/02 ,  D06P5/24 ,  D06P5/28 ,  G03G9/09

CPC classification number: B41M5/38257 ,  B41F16/02 ,  B41J2/01 ,  B41J2/315 ,  B41J2/325 ,  B41J3/407 ,  B41M5/0256 ,  B41M5/035 ,  B44C1/1712 ,  C09D11/32 ,  C09D11/328 ,  C09D11/34 ,  D06P5/003 ,  D06P5/004 ,  D06P5/006 ,  D06P5/007 ,  G03G15/6591 ,  G03G9/0926 ,  B41M5/0356 ,  G03G2215/00527

Abstract: A method of printing a liquid ink which is produced from a heat activated dye which is selected from a limited group of dyes which are capable of transfer at low energy. A printer which uses liquid ink, such as an ink jet printer, prints an image onto an intermediate substrate medium. The dyes contained in the ink are not substantially activated during the process of printing on to the medium. The image formed by the printed ink is transferred from the medium to a final substrate by the application of heat and pressure for a short period of time to activate the ink. The dye and dispersing/emulsifying agent(s) are selected from a limited group to produce an ink which permits thermal transfer at low energy, with the resulting image, as deposited on the final substrate, having an optical density of 1.0 or greater.

Abstract translation: 一种印刷由热活化染料制成的液体油墨的方法，所述热活性染料选自能够以低能量转移的有限组的染料。 使用液体墨水的打印机，例如喷墨打印机，将图像打印到中间基板介质上。 包含在墨水中的染料在印刷到介质的过程中基本上不被活化。 由印刷油墨形成的图像通过在短时间内施加热和压力从介质转移到最终的基板以启动油墨。 染料和分散/乳化剂选自有限的组合以产生允许以低能量进行热转印的油墨，沉积在最终基底上的所得图像具有1.0或更大的光密度。

公开(公告)号：US5728810A

公开(公告)日：1998-03-17

申请号：US425069

申请日：1995-04-19

Applicant: Randolph V. Lewis ,  Ming Xu ,  Michael B. Hinman

Inventor： Randolph V. Lewis ,  Ming Xu ,  Michael B. Hinman

IPC: C07K14/195 ,  C07K14/435 ,  C12N1/21 ,  A61K38/17

CPC classification number: C07K14/195 ,  C07K14/43518 ,  C07K2319/00

Abstract: The present invention is directed to isolated cDNA which codes for spider silk protein or a fragment or variant thereof, a replicable vector containing cDNA which codes for spider silk protein and which is capable of expressing spider silk protein, a transformed cell or microorganism containing cDNA which codes for spider silk protein or a fragment thereof which is capable of expressing spider silk protein and products, such as fibers, which may be manufactured utilizing the recombinant protein of the present invention.

Abstract translation: 本发明涉及编码蜘蛛丝蛋白或其片段或变体的分离的cDNA，包含编码蜘蛛丝蛋白并能够表达蜘蛛丝蛋白的cDNA的可复制载体，含有cDNA的转化细胞或微生物 能够表达蜘蛛丝蛋白的蜘蛛丝蛋白质或其片段的代码，以及可以使用本发明的重组蛋白质制造的产品，例如纤维。

公开(公告)号：US5642141A

公开(公告)日：1997-06-24

申请号：US695121

申请日：1996-08-05

Applicant: Nathan Hale ,  Ming Xu

Inventor： Nathan Hale ,  Ming Xu

IPC: B41F16/02 ,  B41J2/01 ,  B41J2/315 ,  B41J2/325 ,  B41J3/407 ,  B41M5/025 ,  B41M5/035 ,  B41M5/382 ,  B44C1/17 ,  C09D11/00 ,  D06P5/24 ,  D06P5/28 ,  G03G9/09

CPC classification number: C09D11/34 ,  B41F16/02 ,  B41J2/01 ,  B41J2/315 ,  B41J2/325 ,  B41J3/407 ,  B41M5/0256 ,  B41M5/035 ,  B41M5/38257 ,  B44C1/1712 ,  C09D11/32 ,  C09D11/328 ,  D06P5/003 ,  D06P5/004 ,  D06P5/006 ,  D06P5/007 ,  G03G9/0926 ,  B41M5/0356 ,  G03G2215/00527

Abstract: A method of printing a liquid ink which is produced from a heat activated dye which is selected from a limited group of dyes which are capable of transfer at low energy. A printer which uses liquid ink, such as an ink jet printer, prints an image onto an intermediate substrate medium. The dyes contained in the ink are not substantially activated during the process of printing on to the medium. The image formed by the printed ink is transferred from the medium to a final substrate by the application of heat and pressure for a short period of time to activate the ink. The dye and dispersing/emulsifying agent(s) are selected from a limited group to produce an ink which permits thermal transfer at low energy, with the resulting image, as deposited on the final substrate, having an optical density of 1.0 or greater.

Abstract translation: 一种印刷由热活化染料制成的液体油墨的方法，所述热活性染料选自能够以低能量转移的有限组的染料。 使用液体墨水的打印机，例如喷墨打印机，将图像打印到中间基板介质上。 包含在墨水中的染料在印刷到介质的过程中基本上不被活化。 由印刷油墨形成的图像通过在短时间内施加热和压力从介质转移到最终的基板以启动油墨。 染料和分散/乳化剂选自有限的组合以产生允许以低能量进行热转印的油墨，沉积在最终基底上的所得图像具有1.0或更大的光密度。

公开(公告)号：US10051489B2

公开(公告)日：2018-08-14

申请号：US14129259

申请日：2012-05-11

Applicant: Hui Tong ,  Masayuki Hoshino ,  Akihiko Nishio ,  Ming Xu ,  Daichi Imamura

Inventor： Hui Tong ,  Masayuki Hoshino ,  Akihiko Nishio ,  Ming Xu ,  Daichi Imamura

IPC: H04B7/06 ,  H04W24/02 ,  H04L1/00 ,  H04W24/10 ,  H04W88/02

CPC classification number: H04W24/02 ,  H04B7/063 ,  H04B7/0632 ,  H04B7/0639 ,  H04B7/065 ,  H04B7/066 ,  H04L1/0026 ,  H04L1/0027 ,  H04L1/003 ,  H04L1/0031 ,  H04W24/10 ,  H04W88/02

Abstract: Provided is reporting one or more long term CSI components to an eNode B, wherein at least one long term CSI component being reported with multiple values; and reporting a transmission scheme assumption indicator (TSAI) together with a set of short term CSI components to the eNode B, wherein the TSAI indicating the eNode B of a value of the multiple values of the at least one long term CSI component to be currently used and of the set of short term CSI components being conditioned on the value indicated by the TSAI, wherein the short term CSI components being reported more frequently.