Quinoline derivatives, their preparation and pharmaceutical compositions comprising the same
    21.
    发明申请
    Quinoline derivatives, their preparation and pharmaceutical compositions comprising the same 审中-公开
    喹啉衍生物,其制备方法和包含其的药物组合物

    公开(公告)号:US20050165006A1

    公开(公告)日:2005-07-28

    申请号:US10509483

    申请日:2002-04-03

    CPC classification number: A61K31/4709

    Abstract: Novel quinoline derivatives were prepared and evaluated their pharmaceutical activities. The quinoline derivatives according to the present invention effectively bind serotonin transporter (SERT) which is called serotonin reuptake site. Serotonin is one of the neurotransmitter and the lack of its concentration in synapse cause the depression. The quinoline derivatives in this invention can interrupt reuptake of serotonin into presynaptic neuron resulting the increasement of concentration of serotonin in synapse as well as stimulating the signal through the binding with serotonin recepter. Thus, they can be used for the prevention and treatment of mental disorder, especially depression, caused by the deficiency of serotonin concentration in synapse.

    Abstract translation: 制备新型喹啉衍生物并评价其药物活性。 根据本发明的喹啉衍生物有效地结合称为血清素再摄取位点的血清素转运蛋白(SERT)。 血清素是神经递质之一,缺乏其突触浓度导致抑郁。 本发明中的喹啉衍生物可以中断5-羟色胺再突入突触前神经元,导致突触中5-羟色胺的浓度增加,并通过与血清素受体的结合刺激信号。 因此,它们可用于预防和治疗由突触中5-羟色胺浓度不足引起的精神障碍,特别是抑郁症。

    Apparatus for removing contaminant particles on a photomask
    22.
    发明授权
    Apparatus for removing contaminant particles on a photomask 失效
    用于去除光掩模上的污染物颗粒的装置

    公开(公告)号:US06453496B1

    公开(公告)日:2002-09-24

    申请号:US09625009

    申请日:2000-07-25

    Applicant: Byung Chul Lee

    Inventor: Byung Chul Lee

    CPC classification number: H01L21/67028 G11B23/505

    Abstract: An apparatus for removing undesired particles on a target object comprises an electrostatic charge inductor for attracting the undesired particles on the target object, an electrostatic charge developer coming into contact with the electrostatic charge inductor, and a driving source for rotating the electrostatic charge developer. The electrostatic charge developer is rotated by the driving source to be rubbed by the electrostatic charge inductor, which in turn charges the electrostatic charge inductor with negative electricity. The charged inductor attracts the undesired particles off the target object, thereby removing the undesired particles therefrom.

    Abstract translation: 用于去除目标物体上不期望的颗粒的装置包括用于吸引目标物体上的不需要的颗粒的静电电荷感应器,与静电电荷感应器接触的静电荷显影剂,以及用于旋转静电荷显影剂的驱动源。 静电荷显影剂被驱动源旋转以被静电电荷感应器摩擦,静电荷电感依次用负电荷对静电荷感应器充电。 带电电感器将不期望的颗粒吸引到目标物体上,从而从其中去除不期望的颗粒。

    Delamination apparatus and inline thermal imaging system
    23.
    发明授权
    Delamination apparatus and inline thermal imaging system 有权
    分层装置和在线热成像系统

    公开(公告)号:US08869863B2

    公开(公告)日:2014-10-28

    申请号:US13486875

    申请日:2012-06-01

    Abstract: A delamination apparatus includes a stage, a first roll unit, a gripper, and a second roll unit. The stage includes a peripheral area and a substrate area. An edge of a donor film is attached at the peripheral area. An acceptor substrate, laminated at on the donor film, is disposed at the substrate area. The first roll unit is disposed on the donor film, moves in a lengthwise direction of the acceptor substrate. The gripper is disposed on the donor film, and is configured to separate the edge of the donor film from the stage so as to cause the donor film to contact the first roll unit. The second roll unit is disposed on the stage, contacts the donor film which contacts the first roll unit, and delaminates the donor film from the acceptor substrate by moving in the lengthwise direction with the first roll unit.

    Abstract translation: 分层装置包括台,第一卷单元,夹具和第二卷单元。 舞台包括周边区域和衬底区域。 供体膜的边缘附着在周边区域。 层叠在供体膜上的受主衬底设置在衬底区域。 第一辊单元设置在供体膜上,在受主衬底的长度方向上移动。 夹持器设置在供体膜上,并且构造成将施体膜的边缘与载物台分离,以使供体膜与第一辊单元接触。 第二辊单元设置在台架上,与第一辊单元接触供体膜,并且通过与第一辊单元沿长度方向移动,使施主膜从受主衬底分层。

    METHOD AND DEVICE FOR DNA SEQUENCE ANALYSIS USING MULTIPLE PNA
    25.
    发明申请
    METHOD AND DEVICE FOR DNA SEQUENCE ANALYSIS USING MULTIPLE PNA 审中-公开
    使用多PNA的DNA序列分析的方法和设备

    公开(公告)号:US20120282709A1

    公开(公告)日:2012-11-08

    申请号:US13496059

    申请日:2009-09-14

    CPC classification number: C12Q1/6869 C12Q2525/107 C12Q2537/161 C12Q2565/631

    Abstract: Provided are a DNA sequence analysis method of high precision providing improved optical limits by detecting wavelengths of lights emitted from labels in the state where a DNA is electrically tethered and completely stretch, and a nanodevice chip for automating the method. Also provided are a DNA sequence analysis method capable of removing binding errors through complementarily binding between a plurality of peptide nucleic acids (PNAs) labeled with labels emitting lights of different wavelengths and a target DNA to be sequenced, and resolving the limit in optical spatial resolution.

    Abstract translation: 提供了一种高精度的DNA序列分析方法,其通过检测在DNA被电连接并完全拉伸的状态下从标签发射的光的波长来提供改善的光学限制,以及用于使该方法自动化的纳米设备芯片。 还提供了一种DNA序列分析方法,其能够通过在发射不同波长的光的标记的标记的多个肽核酸(PNA)和待测序的靶DNA之间的互补结合来消除结合错误,并且解决光学空间分辨率的限制 。

    BIO-SENSORS INCLUDING NANOCHANNEL INTEGRATED 3-DIMENSIONAL METALLIC NANOWIRE GAP ELECTRODES, MANUFACTURING METHOD THEREOF, AND BIO-DISK SYSTEM COMPRISING THE BIO-SENSORS
    27.
    发明申请
    BIO-SENSORS INCLUDING NANOCHANNEL INTEGRATED 3-DIMENSIONAL METALLIC NANOWIRE GAP ELECTRODES, MANUFACTURING METHOD THEREOF, AND BIO-DISK SYSTEM COMPRISING THE BIO-SENSORS 审中-公开
    包括纳米通道一体化三维金属纳米带隙电极的生物传感器,其制造方法和包含生物传感器的生物磁盘系统

    公开(公告)号:US20090188784A1

    公开(公告)日:2009-07-30

    申请号:US12199793

    申请日:2008-08-27

    CPC classification number: B82Y15/00 G01N27/3278 G01N33/5438 G01N33/553

    Abstract: There are provided a bio-sensor including nanochannel-integrated 3-dimensional metallic nanowire gap electrodes, a manufacturing method thereof, and a bio-disk system comprising the bio-sensor. The bio-sensor includes an upper substrate block having a plurality of metallic nanowires formed on a lower surface thereof and including an injection port through which a biomaterial-containing sample is injected; a lower substrate block having a plurality of metallic nanowires formed on an upper surface thereof; and a supporting unit supporting the upper and lower substrate blocks so that the upper and lower substrate blocks can be disposed spaced apart at a predetermined distance to form a nanochannel, wherein the metallic nanowires formed on the upper and lower substrate blocks are combined to form 3-dimensional metallic nanowire gap electrodes.

    Abstract translation: 提供了包括纳米通道集成的三维金属纳米线间隙电极的生物传感器,其制造方法和包括生物传感器的生物盘系统。 该生物传感器包括具有形成在其下表面上的多个金属纳米线的上基板块,并且包括注入生物材料的样品的注入口; 具有形成在其上表面上的多个金属纳米线的下基板块; 以及支撑单元,其支撑上基板块和下基板块,使得上基板块和下基板块可以以预定距离间隔开设置以形成纳米通道,其中形成在上基板块和下基板块上的金属纳米线被组合形成3 维金属纳米线间隙电极。

    Method of forming contact portion of semiconductor element
    28.
    发明授权
    Method of forming contact portion of semiconductor element 失效
    形成半导体元件的接触部分的方法

    公开(公告)号:US06448183B1

    公开(公告)日:2002-09-10

    申请号:US09710763

    申请日:2000-11-11

    Applicant: Byung-Chul Lee

    Inventor: Byung-Chul Lee

    Abstract: Disclosed is a method for forming a contact portion of a semiconductor element. An exemplary method includes the steps of depositing an insulation layer on a lower thin film on which there is formed a semiconductor element electrode or a metal wiring pattern, and then realizing an even upper surface of the insulation layer; forming a photosensitive film pattern thereon having a contact or via hole pattern in which inner walls of the contact holes or via holes smoothly curve downward to reach an upper surface of the insulation layer; dry-etching the insulation layer using a mask following the photosensitive film pattern to form contact holes or via holes; removing the photosensitive film pattern, then depositing a barrier metal and tungsten to fill the contact holes or the via holes; and performing a chemical mechanical polishing process to remove the barrier metal and the tungsten from the upper surface of the semiconductor element until the insulation layer is exposed and a flat surface is realized.

    Abstract translation: 公开了一种用于形成半导体元件的接触部分的方法。 示例性方法包括以下步骤:在形成有半导体元件电极或金属布线图案的下薄膜上沉积绝缘层,然后实现绝缘层的均匀上表面; 在其上形成具有接触孔或通孔图案的感光膜图案,其中接触孔或通孔的内壁平滑地向下弯曲以到达绝缘层的上表面; 使用与感光膜图案之后的掩模干蚀刻绝缘层以形成接触孔或通孔; 去除感光膜图案,然后沉积阻挡金属和钨以填充接触孔或通孔; 并且进行化学机械抛光工艺以从半导体元件的上表面去除阻挡金属和钨直到绝缘层露出并且实现平坦的表面。

    DELAMINATION APPARATUS AND INLINE THERMAL IMAGING SYSTEM
    30.
    发明申请
    DELAMINATION APPARATUS AND INLINE THERMAL IMAGING SYSTEM 有权
    分层装置和在线热成像系统

    公开(公告)号:US20140008022A1

    公开(公告)日:2014-01-09

    申请号:US13936298

    申请日:2013-07-08

    Abstract: A delamination apparatus that includes a stage to which a lower support, an acceptor substrate disposed on the lower support, and a donor film laminated with the lower support along the edge of the acceptor substrate, interposing the acceptor substrate therebetween are mounted. The delamination apparatus further includes a first gripper disposed in an end side of the stage to move an end of the donor film to a direction far away from the acceptor substrate by gripping the end of the donor film; and a first peeling roll disposed on the donor film to support the donor film disposed between the acceptor substrate and the first gripper, and rotating itself to a direction of the first gripper.

    Abstract translation: 一种分层装置,其包括下部支撑体,设置在下部支撑体上的受主基板和沿着受主基板的边缘与下部支撑体层叠的供体膜,在其间插入受体基板的阶段。 分层装置还包括设置在台架的端侧的第一夹持器,通过夹持施主膜的端部将施主膜的端部移动到远离受主基板的方向; 以及第一剥离辊,其设置在供体膜上以支撑设置在受主基板和第一夹持器之间的供体膜,并且将其自身旋转到第一夹持器的方向。

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