中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

49 records (took 0.02 seconds)

    Process for the microbial production of amino acids by boosted activity of export carriers
    22.
    发明授权
    Process for the microbial production of amino acids by boosted activity of export carriers 失效
    通过出口承运人的加强活动，微生物生产氨基酸的过程

    公开(公告)号：US06858406B1

    公开(公告)日：2005-02-22

    申请号：US09105117

    申请日：1998-06-17

    Applicant: Marina Vrlijc ,  Lothar Eggeling ,  Hermann Sahm

    Inventor： Marina Vrlijc ,  Lothar Eggeling ,  Hermann Sahm

    IPC: C12N15/09 ,  C07K14/34 ,  C12N1/21 ,  C12N15/00 ,  C12N15/31 ,  C12N15/63 ,  C12N15/77 ,  C12P13/04 ,  C12P13/08 ,  C12P21/02 ,  C12R1/15 ,  C12P21/06 ,  C07H21/04 ,  C07K14/00 ,  C12N1/20 ,  C12N5/00

    CPC classification number: C07K14/34 ,  C12N15/77 ,  C12P13/04 ,  C12P13/08

    Abstract: The invention pertains to a process for the microbial production of amino acids. The process involves boosting the export carrier activity and/or export gene expression of a microorganism which produces the desired amino acid. It was found that a single specific gene is responsible for the export of a given amino acid, and on that basis, a process for the microbial production of amino acids, involving the controlled boosting of the export gene expression and/or export carrier activity of a microorganism was developed, which produces the amino acid. The boosted expression or activity of the export carrier resulting from this process increases the secretion rate and thus increases transport of the desired amino acid.

    Abstract translation: 本发明涉及一种微生物生产氨基酸的方法。 该方法包括增加产生所需氨基酸的微生物的出口载体活性和/或导出基因表达。 已经发现，单个特定基因负责输出给定的氨基酸，并且在此基础上，氨基酸的微生物生产过程涉及出口基因表达的受控增强和/或导出载体活性 开发出产生氨基酸的微生物。 由该方法产生的出口载体的增强的表达或活性增加分泌速率，从而增加所需氨基酸的转运。

    Nucleotide sequences which code for the ACP gene
    28.
    发明授权
    Nucleotide sequences which code for the ACP gene 失效
    编码ACP基因的核苷酸序列

    公开(公告)号：US06830921B2

    公开(公告)日：2004-12-14

    申请号：US09852137

    申请日：2001-05-10

    Applicant: Bettina Möckel ,  Anke Weissenborn ,  Walter Pfefferle ,  Hermann Sahm ,  Lothar Eggeling ,  Madhavan Nampoothiri

    Inventor： Bettina Möckel ,  Anke Weissenborn ,  Walter Pfefferle ,  Hermann Sahm ,  Lothar Eggeling ,  Madhavan Nampoothiri

    IPC: C12N120

    CPC classification number: C12P13/08 ,  C07K14/34

    Abstract: The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70 % to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70 % to the amino acid sequence of SEQ ID No. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), a process for the fermentative preparation of L-amino acids with enhancement of the acp gene and the use of the polynucleotide as a primer or hybridization probe.

    Abstract translation: 本发明涉及一种分离的多核苷酸，其包含选自以下的多核苷酸序列：a）与编码包含SEQ ID No.2的氨基酸序列的多肽的多核苷酸的程度相同的多核苷酸 b）编码多肽的多核苷酸，其包含与SEQ ID No.2的氨基酸序列至少70％相同的氨基酸序列，c）与a）的多核苷酸互补的多核苷酸， 或b），和d）多核苷酸，其包含a），b）或c）的多核苷酸序列的至少15个连续核苷酸，具有增强的acp基因的L-氨基酸的发酵制备方法和所述多核苷酸的用途 作为引物或杂交探针。

Patent Agency Ranking