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公开(公告)号:US5668165A
公开(公告)日:1997-09-16
申请号:US475883
申请日:1995-06-07
申请人: Mark A. Wuonola , Zhe Li
发明人: Mark A. Wuonola , Zhe Li
IPC分类号: A61K31/34 , A61K31/341 , A61K31/38 , A61K31/381 , A61P31/12 , C07C255/56 , C07D233/64 , C07D307/54 , C07D333/24 , C07D405/14 , A61K31/415
CPC分类号: C07D307/54 , C07C255/56 , C07D333/24 , C07D405/14
摘要: Disclosed is a method for the inhibition of binding of a ligand to an RNA, the inhibition being mediated by a small organic molecule that binds to the RNA, thereby inhibiting ligand binding. A preferred class of small organic molecules are compounds exemplified by 2,5-Bis[3-(2-N,N-dimethylaminopropylamidino)phenyl]furan.
摘要翻译: 公开了一种抑制配体与RNA的结合的方法,该抑制是由与RNA结合的小的有机分子介导的,从而抑制配体结合。 一类优选的小有机分子是2,5-双[3-(2-N,N-二甲基氨基丙基脒基)苯基]呋喃的化合物。
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公开(公告)号:US10407052B2
公开(公告)日:2019-09-10
申请号:US15837085
申请日:2017-12-11
申请人: Yang Liang , Zhe Li , Jaspal S Sandhu
发明人: Yang Liang , Zhe Li , Jaspal S Sandhu
摘要: A control system for a hybrid transmission of a vehicle, the hybrid transmission having first and second electric motors, comprises a motor speed sensor configured to measure a rotational speed of the first electric motor and a controller. The controller is configured to determine a first difference between a first measured speed and a first expected speed of the first electric motor, when the first difference exceeds a speed threshold indicative of tire slippage, temporarily adjust a torque output of the second electric motor to compensate for an oscillation generated by the first electric motor, after controlling the second electric motor to temporarily adjust its torque output, determine a second difference between a second measured speed and a second expected speed of the first electric motor, and when the second difference does not exceed the speed threshold, control the second electric motor based on a driver torque request.
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公开(公告)号:US20150124500A1
公开(公告)日:2015-05-07
申请号:US14234068
申请日:2012-07-23
申请人: Zhe Li , Min Ho Kim
发明人: Zhe Li , Min Ho Kim
CPC分类号: H02M3/335 , H02M3/33546 , H02M2001/346 , Y02B70/1491
摘要: Provided is an apparatus for controlling a surge voltage. An embodiment configures a snubber coil and a snubber rectifier on a secondary side circuit in series to control a high spike surge voltage across a rectifier on the secondary side. When the rectifier is turned-off, the snubber rectifier is turned-on for a predetermined time to control the surge voltage.
摘要翻译: 提供了一种用于控制浪涌电压的装置。 一个实施例将次级侧电路上的缓冲线圈和缓冲器整流器串联配置,以控制次级侧上的整流器上的高尖峰浪涌电压。 当整流器关断时,缓冲整流器接通预定时间以控制浪涌电压。
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公开(公告)号:US20120044007A1
公开(公告)日:2012-02-23
申请号:US13284614
申请日:2011-10-28
申请人: Zhe Li , Weiping Jie , Junjie Hao
发明人: Zhe Li , Weiping Jie , Junjie Hao
IPC分类号: H03K5/08
CPC分类号: H04B15/005 , H04B2215/063
摘要: A communication device is provided. The communication device includes a circuit for reducing low-frequency interference, and the circuit for reducing low-frequency interference includes a low-frequency filter circuit and a capacitor. The low-frequency filter circuit includes a terminal and a terminal, in which the terminal is connected to a power supply, and the terminal is connected to a load; the capacitor includes a terminal and a terminal, in which the terminal is connected to the load, and the terminal is connected to the power. By setting the circuit for reducing low-frequency interference in a communication device, an input current of the communication device may be maintained stable, as a result, low-frequency interference of the communication device to other communication devices is reduced.
摘要翻译: 提供通信设备。 通信装置包括用于降低低频干扰的电路,并且用于降低低频干扰的电路包括低频滤波器电路和电容器。 低频滤波器电路包括端子和端子,其中端子连接到电源,并且端子连接到负载; 电容器包括端子和端子,其中端子连接到负载,并且端子连接到电源。 通过设置用于降低通信设备中的低频干扰的电路,可以使通信设备的输入电流保持稳定,结果,通信设备对其他通信设备的低频干扰减少。
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公开(公告)号:US20090203687A1
公开(公告)日:2009-08-13
申请号:US12235426
申请日:2008-09-22
申请人: William D. Arnold , Andreas Gosberg , Zhe Li , Ruo W. Steemsma , Mark E. Wilson
发明人: William D. Arnold , Andreas Gosberg , Zhe Li , Ruo W. Steemsma , Mark E. Wilson
IPC分类号: A61K31/5377 , A61K31/437 , A61K31/496 , A61P35/00
CPC分类号: C07D487/04
摘要: The present invention provides novel fused ring heterocycle kinase modulators and methods of using the novel fused ring heterocycle kinase modulators to treat diseases mediated by kinase activity.
摘要翻译: 本发明提供新颖的稠环杂环激酶调节剂和使用新的稠环杂环激酶调节剂来治疗由激酶活性介导的疾病的方法。
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公开(公告)号:US20090143352A1
公开(公告)日:2009-06-04
申请号:US11733758
申请日:2007-04-10
申请人: William D. Arnold , Pierre Bounaud , Chixu Chen , Brian Eastman , Andreas Gosberg , Stefan N. Gradl , Stephanie Hopkins , Zhe Li , Ian McDonald , Paul A. Sprengeler , Ruo W. Steensma , Mark E. Wilson
发明人: William D. Arnold , Pierre Bounaud , Chixu Chen , Brian Eastman , Andreas Gosberg , Stefan N. Gradl , Stephanie Hopkins , Zhe Li , Ian McDonald , Paul A. Sprengeler , Ruo W. Steensma , Mark E. Wilson
IPC分类号: A61K31/541 , C07D471/02 , A61K31/497 , A61K31/437 , A61K31/5377
CPC分类号: C07D471/04 , C07D519/00
摘要: The present invention provides novel pyrrolo-pyridine kinase modulators and methods of using the novel pyrrolo-pyridine kinase modulators to treat diseases mediated by kinase activity.
摘要翻译: 本发明提供新颖的吡咯并 - 吡啶激酶调节剂和使用新型吡咯并 - 吡啶激酶调节剂治疗由激酶活性介导的疾病的方法。
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公开(公告)号:US07434184B2
公开(公告)日:2008-10-07
申请号:US11450701
申请日:2006-06-09
申请人: Zhe Li
发明人: Zhe Li
IPC分类号: G06F17/50
CPC分类号: G06F17/5022
摘要: This method uses 2 copies of the design under test. These 2 copies use different values (including primary inputs and initial states) to feed the supposedly irrelevant logic while using the same (or consistent as desired) values to feed the feature being verified. Symbolic method is used to efficiently determine whether the feature being verified behaves identically (or consistently as expected) in the 2 copies for all possible cases in the supposedly irrelevant logic.
摘要翻译: 该方法使用2份被测设计。 这两个副本使用不同的值(包括主要输入和初始状态)来提供所谓的无关逻辑,同时使用相同的(或一致的)值来馈送被验证的功能。 符号方法用于有效地确定被验证的特征是否与所谓的无关逻辑中的所有可能情况的2个拷贝中的行为相同(或一致地预期)。
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公开(公告)号:US20080116548A1
公开(公告)日:2008-05-22
申请号:US11863259
申请日:2007-09-28
申请人: Zhe Li , Ying-Wei Jiang , Guo-Ping Lu
发明人: Zhe Li , Ying-Wei Jiang , Guo-Ping Lu
IPC分类号: H01L23/495 , B23K31/02
CPC分类号: B23K20/004 , H01L23/495 , H01L24/45 , H01L24/48 , H01L24/78 , H01L24/85 , H01L2224/45015 , H01L2224/45124 , H01L2224/45139 , H01L2224/45144 , H01L2224/45147 , H01L2224/45164 , H01L2224/45169 , H01L2224/4554 , H01L2224/45669 , H01L2224/48247 , H01L2224/48455 , H01L2224/48456 , H01L2224/4846 , H01L2224/4847 , H01L2224/48599 , H01L2224/48699 , H01L2224/78301 , H01L2224/78302 , H01L2224/78306 , H01L2224/78309 , H01L2224/8518 , H01L2224/85201 , H01L2224/85205 , H01L2924/00011 , H01L2924/00014 , H01L2924/01012 , H01L2924/01013 , H01L2924/01014 , H01L2924/0102 , H01L2924/01029 , H01L2924/01033 , H01L2924/01046 , H01L2924/01047 , H01L2924/01074 , H01L2924/01078 , H01L2924/01079 , H01L2924/01082 , H01L2924/014 , H01L2924/20752 , H01L2924/20753 , H01L2924/20754 , H01L2924/20755 , H01L2924/01004 , H01L2924/00 , H01L2924/2075 , H01L2924/013 , H01L2924/00013 , H01L2924/01049 , H01L2924/01006 , H01L2224/85399 , H01L2224/05599 , H01L2224/43848
摘要: In a semiconductor package having a plurality of wire bond interconnections between a semiconductor chip and a chip carrier, a wire bond (20) including a first stitch bond (22) formed at a first location (24) on a bonding site (26), and a second stitch bond (40) formed at a second location (42) on the bonding site (26) such that the second bond (40) forms two crescent shaped areas (48, 50) and overlaps the first bond (22).
摘要翻译: 在半导体芯片和芯片载体之间具有多个引线接合互连的半导体封装中,包括形成在焊接部位(26)上的第一位置(24)处的第一针脚结(22)的引线接合(20) 以及形成在所述接合位置(26)上的第二位置(42)处的第二缝合接合(40),使得所述第二接合(40)形成两个新月形区域(48,50)并与所述第一接合部(22)重叠。
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公开(公告)号:US07361764B2
公开(公告)日:2008-04-22
申请号:US11364872
申请日:2006-02-27
申请人: William D. Arnold , Pierre Bounaud , Andreas Gosberg , Zhe Li , Ian McDonald , Ruo W. Steensma , Mark E. Wilson
发明人: William D. Arnold , Pierre Bounaud , Andreas Gosberg , Zhe Li , Ian McDonald , Ruo W. Steensma , Mark E. Wilson
IPC分类号: C07D471/02
CPC分类号: C07D471/04
摘要: The present invention provides novel pyrrolo-pyridine kinase modulators and methods of using the novel pyrrolo-pyridine kinase modulators to treat diseases mediated by kinase activity.
摘要翻译: 本发明提供新颖的吡咯并 - 吡啶激酶调节剂和使用新型吡咯并 - 吡啶激酶调节剂治疗由激酶活性介导的疾病的方法。
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公开(公告)号:US06548521B1
公开(公告)日:2003-04-15
申请号:US09628080
申请日:2000-07-28
申请人: Fred Ehrenkranz Cohen , James Hobson McKerrow , Christine Sun Ring , Philip Jon Rosenthal , George Lommel Kenyon , Zhe Li
发明人: Fred Ehrenkranz Cohen , James Hobson McKerrow , Christine Sun Ring , Philip Jon Rosenthal , George Lommel Kenyon , Zhe Li
IPC分类号: A61K31404
CPC分类号: A61K31/472 , A61K31/12 , A61K31/135 , A61K31/136 , A61K31/165 , A61K31/17 , A61K31/195 , A61K31/34 , A61K31/35 , A61K31/36 , A61K31/365 , A61K31/40 , A61K31/415 , A61K31/4164 , A61K31/4178 , A61K31/44 , A61K31/4402 , A61K31/4406 , A61K31/47 , A61K31/50 , A61K31/505 , A61K31/60 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/423 , Y02A50/491
摘要: Compositions and methods for treating a patient infected with a metazoan parasite by inhibiting the enzymatic action of the metazoan parasite protease, wherein there is employed at least one compound of formula I A—X—B wherein A is a substituted or unsubstituted homoaromatic or heteroaromatic ring system comprising one to three rings which binds to at least one of the S2, S1 and S1′ subsites; B is a substituted or unsubstituted homoaromatic or heteroaromatic ring system comprising one to three rings which binds to at least one of the S1′, S1 and S2 subsites; and X is —C═C—C(═O)—. These compositions and methods have particular utility in the treatment of schistosomiasis, malaria, and other infectious diseases.
摘要翻译: 通过抑制后生动物寄生虫蛋白酶的酶作用来治疗感染后生动物寄生虫的患者的组合物和方法,其中使用至少一种式I的化合物,其中A是取代或未取代的具有一至三个环的同位素或杂芳族环系统 其结合S2,S1和S1'子集中的至少一个; B是取代或未取代的具有与至少一个S1',S1和S2亚亲属结合的一至三个环的同位素或杂芳族环系统; 且X为-C = C-C(= O) - 。 这些组合物和方法在治疗血吸虫病,疟疾和其他传染病方面具有特殊的用途。
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