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公开(公告)号:US20180199873A1
公开(公告)日:2018-07-19
申请号:US15874503
申请日:2018-01-18
Applicant: DexCom, Inc.
Inventor: Shanger Wang , Devon M. Headen , Sebastian Bohm , Jonathan Hughes , Ted Tang Lee , Peter C. Simpson , Jiong Zou
IPC: A61B5/1486 , G01N27/327 , A61B5/00 , C12Q1/00 , C12Q1/54
CPC classification number: A61B5/14865 , A61B5/0022 , A61B5/14532 , A61B5/14546 , A61B2562/125 , A61B2562/164 , C12Q1/002 , C12Q1/006 , C12Q1/54 , G01N27/3271
Abstract: Flexible analyte sensors are provided. Flexible analyte sensors may be flexible continuous analyte sensors that facilitate continuous monitoring of an analyte such as blood glucose. The flexible analyte sensor may have a relatively flexible conductive or non-conductive core, may be formed from a plurality of substantially planar layers, or may be configured to transform from a freestanding sensor ex vivo to a non-freestanding sensor in vivo.
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公开(公告)号:US20170188916A1
公开(公告)日:2017-07-06
申请号:US15395892
申请日:2016-12-30
Applicant: DexCom, Inc.
Inventor: Shanger Wang , Robert J. Boock , Andrew Trinin Dennis , Ted Tang Lee , Jeff T. Suri , David Sze , Mark A Tapsak , Huashi Zhang , Jiong Zou
CPC classification number: G01N27/3273 , A61B5/0004 , A61B5/002 , A61B5/14532 , A61B5/14546 , A61B5/1473 , A61B5/1486 , A61B5/14865 , A61B2562/12 , A61K31/045 , A61K31/137 , A61K31/46 , A61K31/465 , A61K31/485 , A61K31/515 , A61K31/56 , A61K33/00 , A61K36/185 , A61K38/28 , C08G18/0828 , C08G18/12 , C08G18/3857 , C08G18/4018 , C08G18/44 , C08G18/4833 , C08G18/755 , C08L39/06 , C08L69/00 , C08L75/04 , C12N11/08 , C12Q1/002 , C12Q1/006 , G01N27/3275 , G01N33/66 , C08G18/3234
Abstract: Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises a biointerface layer which interfaces with a biological fluid containing the analyte to be measured. The biointerface layer can comprises a biointerface polymer, wherein the biointerface polymer comprises polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The sensing membrane can also comprise an enzyme layer, wherein the enzyme layer comprises an enzyme and a polymer comprising polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The sensing membrane can also comprise a diffusion-resistance layer, which can comprise a base polymer having a lowest Tg of greater than −50 C.
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公开(公告)号:US11943876B2
公开(公告)日:2024-03-26
申请号:US16168715
申请日:2018-10-23
Applicant: DexCom, Inc.
Inventor: Jason Halac , John Charles Barry , Becky L. Clark , Chris W. Dring , John Michael Gray , Kris Elliot Higley , Jeff Jackson , David A. Keller , Ted Tang Lee , Jason Mitchell , Kenneth Pirondini , David Rego , Ryan Everett Schoonmaker , Peter C. Simpson , Craig Thomas Gadd , Kyle Thomas Stewart , John Stanley Hayes
IPC: A61B5/145 , A61B5/00 , A61B5/1459 , A61B5/1473 , A61B5/1486 , A61B5/1495 , A61M5/142 , A61M5/172 , A61M5/20 , A61M11/00 , A61M15/00 , A61M35/00 , G01N27/327 , G01N33/66 , G16H20/17 , G16H40/63 , H05K3/32 , A61M5/00 , A61M5/178 , A61M5/30
CPC classification number: H05K3/321 , A61B5/14532 , A61B5/14546 , A61B5/1459 , A61B5/1473 , A61B5/14865 , A61B5/1495 , A61B5/6801 , A61B5/6849 , A61M5/14244 , A61M5/14276 , A61M5/1723 , A61M5/20 , A61M11/00 , A61M15/0065 , A61M15/0068 , A61M15/008 , A61M15/0083 , A61M35/00 , G01N27/3273 , G01N27/3274 , G01N33/66 , G16H20/17 , G16H40/63 , A61B5/0031 , A61B2560/0468 , A61B2562/043 , A61B2562/08 , A61B2562/085 , A61B2562/12 , A61B2562/125 , A61B2562/16 , A61M5/003 , A61M2005/14296 , A61M5/178 , A61M5/30 , A61M15/00 , A61M2205/3569 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/587 , A61M2205/8206 , A61M2230/201 , Y10T29/49169
Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.
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公开(公告)号:US20230062342A1
公开(公告)日:2023-03-02
申请号:US17977908
申请日:2022-10-31
Applicant: DexCom, Inc.
Inventor: Jason Halac , John Charles Barry , Becky L. Clark , Chris W. Dring , John Michael Gray , Kris Elliot Higley , Jeff Jackson , David A. Keller , Ted Tang Lee , Jason Mitchell , Kenneth Pirondini , David Rego , Ryan Everett Schoonmaker , Peter C. Simpson , Craig Thomas Gadd , Kyle Thomas Stewart , John Stanley Hayes
IPC: A61B5/1473 , A61B5/1486 , A61B5/145 , G01N27/327 , A61B5/1459 , G01N33/66 , A61B5/1495 , A61B5/00 , A61M15/00 , G16H20/17 , G16H40/63 , A61M5/142 , A61M5/172 , A61M5/20 , A61M11/00 , A61M35/00 , H05K3/32
Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.
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公开(公告)号:US11382540B2
公开(公告)日:2022-07-12
申请号:US16167976
申请日:2018-10-23
Applicant: DexCom, Inc.
Inventor: Jason Halac , John Charles Barry , Becky L. Clark , Chris W. Dring , John Michael Gray , Kris Elliot Higley , Jeff Jackson , David A. Keller , Ted Tang Lee , Jason Mitchell , Kenneth Pirondini , David Rego , Ryan Everett Schoonmaker , Peter C. Simpson , Craig Thomas Gadd , Kyle Thomas Stewart , John Stanley Hayes
IPC: A61B5/1486 , A61B5/145 , A61B5/1495 , A61B5/00 , A61B5/1473 , G01N27/327 , G01N33/66 , A61M15/00 , G16H20/17 , G16H40/63 , A61M5/142 , A61M5/172 , A61M5/20 , A61M11/00 , A61M35/00 , H05K3/32 , A61B5/1459 , A61M5/00 , A61M5/178 , A61M5/30
Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.
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公开(公告)号:US11350862B2
公开(公告)日:2022-06-07
申请号:US17464547
申请日:2021-09-01
Applicant: DexCom, Inc.
Inventor: Jason Halac , John Charles Barry , Becky L. Clark , Chris W. Dring , John Michael Gray , Kris Elliot Higley , Jeff Jackson , David A. Keller , Ted Tang Lee , Jason Mitchell , Kenneth Pirondini , David Rego , Ryan Everett Schoonmaker , Peter C. Simpson , Craig Thomas Gadd , Kyle Thomas Stewart , John Stanley Hayes
IPC: A61B5/1473 , A61B5/1486 , A61B5/145 , G01N27/327 , A61B5/1459 , G01N33/66 , A61B5/1495 , A61B5/00 , A61M15/00 , G16H20/17 , G16H40/63 , A61M5/142 , A61M5/172 , A61M5/20 , A61M11/00 , A61M35/00 , H05K3/32 , A61M5/00 , A61M5/178 , A61M5/30
Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.
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公开(公告)号:US11262326B2
公开(公告)日:2022-03-01
申请号:US15395892
申请日:2016-12-30
Applicant: DexCom, Inc.
Inventor: Shanger Wang , Robert J. Boock , Andrew Trinin Dennis , Ted Tang Lee , Jeff T. Suri , David Sze , Mark A Tapsak , Huashi Zhang , Jiong Zou
IPC: A61B5/145 , G01N27/327 , C08G18/08 , C08G18/48 , C08G18/40 , C08G18/38 , C08G18/12 , C08G18/44 , C08G18/75 , C12N11/089 , C12N11/093 , C08L39/06 , C08L69/00 , C08L75/04 , C12Q1/00 , A61B5/00 , A61B5/1486 , G01N33/66 , A61K31/045 , A61K31/137 , A61K31/46 , A61K31/465 , A61K31/485 , A61K31/515 , A61K31/56 , A61K33/00 , A61K36/185 , A61K38/28 , A61B5/1473
Abstract: Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises a biointerface layer which interfaces with a biological fluid containing the analyte to be measured. The biointerface layer can comprises a biointerface polymer, wherein the biointerface polymer comprises polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The sensing membrane can also comprise an enzyme layer, wherein the enzyme layer comprises an enzyme and a polymer comprising polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The sensing membrane can also comprise a diffusion-resistance layer, which can comprise a base polymer having a lowest Tg of greater than −50 C.
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公开(公告)号:US11058329B2
公开(公告)日:2021-07-13
申请号:US15798249
申请日:2017-10-30
Applicant: DexCom, Inc.
Inventor: Peter C. Simpson , Minglian Shi , Sebastian Bohm , Maria Noel Brown Wells , John Patrick Majewski , Leah Morta Edra , Disha B. Sheth , John Michael Gray , Shanger Wang , Ted Tang Lee , Michael L. Moore , Jason Mitchell , Jennifer Blackwell , Neel Narayan Shah , Todd Andrew Newhouse , Jason Halac , Ryan Everett Schoonmaker , Paul V. Neale , Jiong Zou , Sean T. Saint
IPC: A61B5/145 , A61B5/00 , A61B5/1473 , A61B5/1486
Abstract: Sensor systems can be used to measure an analyte concentration. Sensor systems can include a base having a distal side configured to face towards a person's skin. An adhesive can couple the base to the skin. A transcutaneous analyte measurement sensor can be coupled to the base and can be located at least partially in the host. A transmitter can be coupled to the base and can transmit analyte measurement data to a remote device.
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公开(公告)号:US20190339224A1
公开(公告)日:2019-11-07
申请号:US16402124
申请日:2019-05-02
Applicant: DexCom, Inc.
Inventor: Naresh C. Bhavaraju , Becky L. Clark , Vincent P. Crabtree , Chris W. Dring , Arturo Garcia , Jason Halac , Jonathan Hughes , Jeff Jackson , Lauren Hruby Jepson , David I-Chun Lee , Ted Tang Lee , Rui Ma , Zebediah L. McDaniel , Jason Mitchell , Andrew Attila Pal , Daiting Rong , Disha B. Sheth , Peter C. Simpson , Stephen J. Vanslyke , Matthew D. Wightlin , Anna Leigh Davis , Hari Hampapuram , Aditya Sagar Mandapaka , Alexander Leroy Teeter , Liang Wang
IPC: G01N27/327
Abstract: Systems and methods are provided that address the need to frequently calibrate analyte sensors, according to implementation. In more detail, systems and methods provide a preconnected analyte sensor system that physically combines an analyte sensor to measurement electronics during the manufacturing phase of the sensor and in some cases in subsequent life phases of the sensor, so as to allow an improved recognition of sensor environment over time to improve subsequent calibration of the sensor.
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公开(公告)号:US20190339221A1
公开(公告)日:2019-11-07
申请号:US16402013
申请日:2019-05-02
Applicant: DexCom, Inc.
Inventor: Naresh C. Bhavaraju , Becky L. Clark , Vincent P. Crabtree , Chris W. Dring , Arturo Garcia , Jason Halac , Jonathan Hughes , Jeff Jackson , Lauren Hruby Jepson , David I-Chun Lee , Ted Tang Lee , Rui Ma , Zebediah L. McDaniel , Jason Mitchell , Andrew Attila Pal , Daiting Rong , Disha B. Sheth , Peter C. Simpson , Stephen J. Vanslyke , Matthew D. Wightlin , Anna Leigh Davis , Hari Hampapuram , Aditya Sagar Mandapaka , Alexander Leroy Teeter , Liang Wang
IPC: G01N27/327
Abstract: Systems and methods are provided that address the need to frequently calibrate analyte sensors, according to implementation. In more detail, systems and methods provide a preconnected analyte sensor system that physically combines an analyte sensor to measurement electronics during the manufacturing phase of the sensor and in some cases in subsequent life phases of the sensor, so as to allow an improved recognition of sensor environment over time to improve subsequent calibration of the sensor.
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