公开(公告)号：US10207041B2

公开(公告)日：2019-02-19

申请号：US15263582

申请日：2016-09-13

Applicant: Medtronic, Inc.

Inventor： Orhan Soykan ,  VenKatesh R. Manda ,  Martin T. Gerber ,  Christopher M. Hobot

IPC: A61B5/0205 ,  A61B5/0452 ,  A61M1/16 ,  A61B5/0402 ,  A61B5/145 ,  A61M1/14 ,  A61B5/04 ,  A61B5/00

Abstract: A medical monitoring device for monitoring electrical signals from the body of a subject is described. The medical monitoring device monitors electrical signals originating from a cardiac cycle of the subject and associates each cardiac cycle with a time index. The medical monitoring device applies a forward computational procedure to generate a risk score indicative of hyperkalemia, hypokalemia or arrhythmia of the subject. The medical monitoring device can adjust the forward computational procedure based upon clinical data obtained from the subject.

公开(公告)号：US20170361006A1

公开(公告)日：2017-12-21

申请号：US15693535

申请日：2017-09-01

Applicant: Medtronic, Inc.

Inventor： Martin Gerber ,  John Burnes ,  SuPing Lyu ,  VenKatesh R. Manda ,  Bryant Pudil

IPC: A61M1/16 ,  A61M1/36 ,  A61B5/00 ,  A61B5/026 ,  A61B5/0295 ,  A61M1/28 ,  A61B5/145 ,  A61M1/00 ,  A61M1/14 ,  B01D65/02 ,  B01D61/32 ,  B01D61/00 ,  A61M1/34 ,  A61B5/053

Abstract: Methods for monitoring patient parameters and blood fluid removal system parameters include identifying those system parameters that result in improved patient parameters or in worsened patient parameters. By comparing the patient's past responses to system parameters or changes in system parameters, a blood fluid removal system may be able to avoid future use of parameters that may harm the patient and may be able to learn which parameters are likely to be most effective in treating the patient in a blood fluid removal session.

公开(公告)号：US20170281847A1

公开(公告)日：2017-10-05

申请号：US15478576

申请日：2017-04-04

Applicant: Medtronic, Inc.

Inventor： VenKatesh R. Manda ,  Martin T. Gerber ,  Christopher M. Hobot ,  David B. Lura ,  Thomas E. Meyer

IPC: A61M1/28 ,  A61L2/00 ,  A61K31/715 ,  A61K31/198 ,  A61K33/00 ,  A61K31/7004

Abstract: Systems and methods of generating and regenerating peritoneal dialysate are provided. The systems and methods use a dialysate regeneration module, a sterilization module and concentrates to prepare peritoneal dialysate from used peritoneal dialysate or source water. An optional integrated cycler for direct infusion of the generated peritoneal dialysate is included. Optional dialysate storage containers are provided for storage of the peritoneal dialysate prior to use.

公开(公告)号：US09597440B2

公开(公告)日：2017-03-21

申请号：US14613725

申请日：2015-02-04

Applicant: Medtronic, Inc.

Inventor： Martin Gerber ,  John Burnes ,  Suping Lyu ,  VenKatesh R. Manda ,  Bryant Pudil

IPC: A61M37/00 ,  C02F1/44 ,  A61M1/16 ,  A61B5/145 ,  A61B5/00 ,  A61B5/026 ,  A61B5/053 ,  A61M1/34 ,  B01D65/02 ,  A61M1/00 ,  A61B5/0295 ,  A61M1/14 ,  B01D61/00 ,  B01D61/32 ,  A61M1/36 ,  A61M1/28

CPC classification number: A61M1/1603 ,  A61B5/0031 ,  A61B5/026 ,  A61B5/0295 ,  A61B5/053 ,  A61B5/0537 ,  A61B5/145 ,  A61B5/14503 ,  A61B5/14535 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/4836 ,  A61B5/4848 ,  A61B5/4875 ,  A61B5/6866 ,  A61B5/7282 ,  A61B2560/0223 ,  A61M1/00 ,  A61M1/14 ,  A61M1/16 ,  A61M1/1601 ,  A61M1/1605 ,  A61M1/1607 ,  A61M1/1613 ,  A61M1/28 ,  A61M1/34 ,  A61M1/3403 ,  A61M1/342 ,  A61M1/3607 ,  A61M1/3609 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3672 ,  A61M2202/0498 ,  A61M2205/04 ,  A61M2205/18 ,  A61M2205/33 ,  A61M2205/3303 ,  A61M2205/3306 ,  A61M2205/3313 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3375 ,  A61M2205/3523 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/60 ,  A61M2205/70 ,  A61M2230/00 ,  A61M2230/005 ,  A61M2230/06 ,  A61M2230/20 ,  A61M2230/207 ,  A61M2230/208 ,  A61M2230/65 ,  B01D61/00 ,  B01D61/32 ,  B01D65/02 ,  B01D2321/12 ,  B01D2321/40 ,  G06F19/00

Abstract: A method includes initiating a blood fluid removal session of a patient; monitoring an indicator of tissue fluid volume of the patient, or a portion thereof, during the blood fluid removal session; monitoring an indicator of blood fluid volume of the patient during the blood fluid removal session; determining whether a ratio of the indicator of tissue fluid volume to indicator of blood fluid volume is outside of a predetermined range; and altering the rate of fluid removal during the blood fluid removal session if the ratio is determined to be outside of the predetermined range. A blood fluid removal system may be configured to carry out the method.

公开(公告)号：US20150367054A1

公开(公告)日：2015-12-24

申请号：US14828990

申请日：2015-08-18

Applicant: Medtronic, Inc.

Inventor： Martin Gerber ,  John Burnes ,  Suping Lyu ,  VenKatesh R. Manda ,  Bryant Pudil

IPC: A61M1/16 ,  A61M1/28

CPC classification number: A61M1/1601 ,  A61B5/0031 ,  A61B5/026 ,  A61B5/0295 ,  A61B5/053 ,  A61B5/0537 ,  A61B5/145 ,  A61B5/14503 ,  A61B5/14535 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/4836 ,  A61B5/4848 ,  A61B5/4875 ,  A61B5/6866 ,  A61B5/7282 ,  A61B2560/0223 ,  A61M1/00 ,  A61M1/14 ,  A61M1/16 ,  A61M1/1603 ,  A61M1/1605 ,  A61M1/1607 ,  A61M1/1613 ,  A61M1/28 ,  A61M1/34 ,  A61M1/3403 ,  A61M1/342 ,  A61M1/3607 ,  A61M1/3609 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3672 ,  A61M2202/0498 ,  A61M2205/04 ,  A61M2205/18 ,  A61M2205/33 ,  A61M2205/3303 ,  A61M2205/3306 ,  A61M2205/3313 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3375 ,  A61M2205/3523 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/60 ,  A61M2205/70 ,  A61M2230/00 ,  A61M2230/005 ,  A61M2230/06 ,  A61M2230/20 ,  A61M2230/207 ,  A61M2230/208 ,  A61M2230/65 ,  B01D61/00 ,  B01D61/32 ,  B01D65/02 ,  B01D2321/12 ,  B01D2321/40 ,  G06F19/00

Abstract: Methods include monitoring indicators of blood pH or blood electrolyte levels during a blood fluid removal session and adjusting concentrations of pH buffers or electrolytes in dialysate or replacement fluid used during the session based on the monitored indicators. Blood fluid removal systems may employ sensors that monitor blood pH or electrolyte levels to adjust the fluid parameters during a blood fluid removal session.

公开(公告)号：US20150352269A1

公开(公告)日：2015-12-10

申请号：US14828979

申请日：2015-08-18

Applicant: MEDTRONIC, INC.

Inventor： Martin Gerber ,  John Burnes ,  Suping Lyu ,  VenKatesh R. Manda ,  Bryant Pudil

IPC: A61M1/16

CPC classification number: A61M1/1601 ,  A61B5/0031 ,  A61B5/026 ,  A61B5/0295 ,  A61B5/053 ,  A61B5/0537 ,  A61B5/145 ,  A61B5/14503 ,  A61B5/14535 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/4836 ,  A61B5/4848 ,  A61B5/4875 ,  A61B5/6866 ,  A61B5/7282 ,  A61B2560/0223 ,  A61M1/00 ,  A61M1/14 ,  A61M1/16 ,  A61M1/1603 ,  A61M1/1605 ,  A61M1/1607 ,  A61M1/1613 ,  A61M1/28 ,  A61M1/34 ,  A61M1/3403 ,  A61M1/342 ,  A61M1/3607 ,  A61M1/3609 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3672 ,  A61M2202/0498 ,  A61M2205/04 ,  A61M2205/18 ,  A61M2205/33 ,  A61M2205/3303 ,  A61M2205/3306 ,  A61M2205/3313 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3375 ,  A61M2205/3523 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/60 ,  A61M2205/70 ,  A61M2230/00 ,  A61M2230/005 ,  A61M2230/06 ,  A61M2230/20 ,  A61M2230/207 ,  A61M2230/208 ,  A61M2230/65 ,  B01D61/00 ,  B01D61/32 ,  B01D65/02 ,  B01D2321/12 ,  B01D2321/40 ,  G06F19/00

Abstract: Methods include monitoring indicators of blood pH or blood electrolyte levels during a blood fluid removal session and adjusting concentrations of pH buffers or electrolytes in dialysate or replacement fluid used during the session based on the monitored indicators. Blood fluid removal systems may employ sensors that monitor blood pH or electrolyte levels to adjust the fluid parameters during a blood fluid removal session.

Abstract translation: 方法包括监测血液流体清除过程中血液pH值或血液电解质水平的指标，并根据监测的指标调整会话期间使用的透析液或替代液体中pH缓冲液或电解质的浓度。 血液清除系统可以使用监测血液pH值或电解质水平的传感器，以在血液清除期间调整流体参数。