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公开(公告)号：US12130297B2
公开(公告)日：2024-10-29
申请号：US16938284
申请日：2020-07-24
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. Glezer , Carl Edens , Bandele Jeffrey-Coker , Sandor Kovacs , Christopher Frye
IPC: G01N35/00 , B01F11/00 , B01F31/22 , B06B1/16 , G01N33/543 , G01N35/10 , B01F101/23
CPC classification number: G01N35/00029 , B01F31/22 , B06B1/16 , B06B1/167 , G01N33/54366 , G01N35/00732 , G01N35/0099 , G01N35/10 , B01F2101/23 , G01N2035/00148
Abstract: The present invention relates to a system for performing assays on a solid phase to measure the level of analyte in a sample. Such a system may perform immunoassays using electrochemiluminescence (ECL) including a counterbalanced orbital shaking apparatus for assay consumables.
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公开(公告)号：US11982871B2
公开(公告)日：2024-05-14
申请号：US17492187
申请日：2021-10-01
Applicant: Meso Scale Technologies, LLC.
Inventor： Ian Chamberlin , Charles M. Clinton , Eli N. Glezer , Bandele Jeffrey-Coker , Manish Kochar , Sandor Kovacs , D. T. Le , Aaron Leimkuehler , George Sigal , Leo Tabakin , Jon Willoughby
CPC classification number: G02B7/36 , G01N21/253 , G01N21/6452 , G01N35/028
Abstract: Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format.
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公开(公告)号：US11892455B2
公开(公告)日：2024-02-06
申请号：US17061095
申请日：2020-10-01
Applicant: Meso Scale Technologies, LLC
Inventor： Charles M. Clinton , Eli N. Glezer , Bandele Jeffrey-Coker , Sandor L. Kovacs , Sudeep M. Kumar , George Sigal , Carl Stevens , Michael Vock
IPC: G01N35/10 , B67B7/00 , G01N33/58 , G01N21/64 , G01N21/66 , G01N33/53 , G01N35/02 , B01L3/00 , G01N35/04
CPC classification number: G01N33/582 , B01L3/5085 , B01L3/50255 , B67B7/24 , G01N21/6452 , G01N21/66 , G01N33/5302 , G01N35/028 , G01N35/1011 , G01N35/1079 , G01N35/1081 , G01N35/1002 , G01N35/109 , G01N2035/0405 , G01N2035/0425 , G01N2035/1025 , Y10T83/9314
Abstract: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
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公开(公告)号：US11686739B2
公开(公告)日：2023-06-27
申请号：US17412688
申请日：2021-08-26
Applicant: Meso Scale Technologies, LLC.
Inventor： Manish Kochar , Peter J. Bosco , Ian D. Chamberlin , Bandele Jeffrey-Coker , Eric M. Jones , Aaron H. Leimkuehler , Kim-Xuan Nguyen , Pankaj Oberoi , Louis W. Pang , Jennifer Parker , Victor Pellicier , Nicholas Sammons , George Sigal , Jacob N. Wohlstadter , Stanley T. Smith , Carl C. Stevens , Rodger D. Osborne , Kenneth E. Page
IPC: G01N35/00 , B01L3/00 , B01L9/00 , G16H40/67 , G16H10/40 , G16H40/40 , F24F11/30 , G06K7/14 , G06Q10/087 , G06Q10/10 , H04B1/3827
CPC classification number: G01N35/0099 , B01L3/50853 , B01L9/523 , F24F11/30 , G06K7/1413 , G06Q10/087 , G06Q10/10 , G16H10/40 , G16H40/40 , G16H40/67 , B01L2200/143 , B01L2300/021 , G01N2035/00356 , G05B2219/40269 , H04B1/3827
Abstract: The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.
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公开(公告)号：US20210339243A1
公开(公告)日：2021-11-04
申请号：US17378294
申请日：2021-07-16
Applicant: MESO SCALE TECHNOLOGIES, LLC
Inventor： Eli N. GLEZER , Bandele Jeffrey-Coker , Jeffery D. Debad , Sudeep M. Kumar , George B. Sigal , Bisbert Spieles , Michael Tsionsky , Michael Warnock
IPC: B01L3/00 , G01N33/543 , G01N33/53
Abstract: We describe assay modules (e.g., assay plates, cartridges, multi-well assay plates, reaction vessels, etc.), processes for their preparation, and method of their use for conducting assays. Reagents may be present in free form or supported on solid phases including the surfaces of compartments (e.g., chambers, channels, flow cells, wells, etc.) in the assay modules or the surface of colloids, beads, or other particulate supports. In particular, dry reagents can be incorporated into the compartments of these assay modules and reconstituted prior to their use in accordance with the assay methods. A desiccant material may be used to maintain and stabilize these reagents in a dry state.
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Patent Agency Ranking
公开(公告)号：US11156801B2
公开(公告)日：2021-10-26
申请号：US16360257
申请日：2019-03-21
Applicant: Meso Scale Technologies, LLC.
Inventor： Ian Chamberlin , Charles M. Clinton , Eli N. Glezer , Bandele Jeffrey-Coker , Manish Kochar , Sandor Kovacs , D. T. Le , Aaron Leimkuehler , George Sigal , Leo Tabakin , Jon Willoughby
Abstract: Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format.
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公开(公告)号：US20210055287A1
公开(公告)日：2021-02-25
申请号：US17090367
申请日：2020-11-05
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. Glezer , Jonathan K. Leland , Mark A. Billadeau , Joseph M. Leginus , Bandele Jeffrey-Coker , Jeffery D. Debad , Koustubh A. Phalnikar , Sriram Jambunathan
Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.
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公开(公告)号：US20210033523A1
公开(公告)日：2021-02-04
申请号：US16996418
申请日：2020-08-18
Applicant: Meso Scale Technologies, LLC.
Inventor： Jacob N. Wohlstadter , Eli Glezer , James Wilbur , George Sigal , Kent Johnson , Charles Clinton , Alan Kishbaugh , Bandele Jeffrey-Coker , Jeff D. Debad , Alan B. Fischer
Abstract: Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adopted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
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公开(公告)号：USD829336S1
公开(公告)日：2018-09-25
申请号：US29577664
申请日：2016-09-14
Applicant: Meso Scale Technologies, LLC.
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公开(公告)号：US20160356722A1
公开(公告)日：2016-12-08
申请号：US15222674
申请日：2016-07-28
Applicant: Meso Scale Technologies, LLC.
Inventor： Eli N. Glezer , Jonathan K. Leland , Mark A. Billadeau , Joseph M. Leginus , Bandele Jeffrey-Coker , Jeffery D. Debad , Koustubh A. Phalnikar , Sriram Jambunathan
IPC: G01N21/76 , C12Q1/00 , B01L9/00 , G01N33/543 , B01J19/00
CPC classification number: G01N21/76 , B01J19/0046 , B01J2219/00653 , B01J2219/00725 , B01J2219/0074 , B01L3/5027 , B01L3/502715 , B01L3/5029 , B01L9/527 , B01L2200/0684 , B01L2200/10 , B01L2300/0645 , B01L2300/0681 , B01L2300/0816 , B01L2300/0867 , B01L2300/0887 , B01L2400/049 , B01L2400/0688 , B33Y80/00 , C12Q1/001 , C40B40/10 , G01N27/30 , G01N33/5438 , G01N2458/30 , Y10T436/25 , Y10T436/25375 , Y10T436/255
Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.
Abstract translation: 测定模块，优选测定盒，被描述为可用于控制模块操作的方面的读取器设备。 模块优选地包括具有集成电极的检测室，其可用于执行电极诱导的发光测量。 描述了以这种控制方式将测定试剂固定在这些电极和其它表面上的方法。 还描述了具有检测室，优选地具有集成电极的测定模块和盒，以及可以包括样品室，废物室，导管，通风口，气泡阱，试剂室，干试剂丸区等的其它流体组分。 在某些优选实施例中，这些模块适于接收和分析在施用器棒上收集的样品。
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