公开(公告)号：US20060173043A1

公开(公告)日：2006-08-03

申请号：US10564653

申请日：2004-07-15

申请人： Gyoon Han ,  Hwan Kim ,  Song Park ,  Chang-Woo Lee ,  Sang Han ,  Ki Lee ,  Yung Kho ,  Jin Yang ,  Bum Park ,  Hyang Lee ,  Jeung Han ,  Dong Ryu ,  Jin Lee ,  Tae Chun ,  Yong Kim ,  Hee Lee ,  Bong Lee ,  Jeom Kim ,  Ji Kim ,  Kyunga Yu ,  Sun Kim

发明人： Gyoon Han ,  Hwan Kim ,  Song Park ,  Chang-Woo Lee ,  Sang Han ,  Ki Lee ,  Yung Kho ,  Jin Yang ,  Bum Park ,  Hyang Lee ,  Jeung Han ,  Dong Ryu ,  Jin Lee ,  Tae Chun ,  Yong Kim ,  Hee Lee ,  Bong Lee ,  Jeom Kim ,  Ji Kim ,  Kyunga Yu ,  Sun Kim

IPC分类号： A61K31/4545 ,  A61K31/454

CPC分类号： A61K31/454 ,  A61K31/4015 ,  A61K31/4545 ,  C07D207/38 ,  C07D211/86 ,  C07D223/10 ,  C07D417/06

摘要： The present invention is related to novel use of 2-oxo-heterocyclic compounds having anticancer activity and the process for preparing them and a pharmaceutical composition comprising the same. The present invention provides a pharmaceutical composition for preventing and treating the cancer disease comprising lung cancer, bone cancer, pancreatic cancer, skin cancer, cancer of the head and neck, cutaneous or intraocular melanoma, uterine cancer, ovarian cancer, rectal cancer or cancer of the anal region, stomach cancer, colon cancer, breast cancer, gynecologic tumors, Hodgkin's disease, cancer of the esophagus, cancer of the small intestine, cancer of the endocrine system, sarcomas of soft tissues, cancer of the urethra, cancer of the penis, prostate cancer, chronic or acute leukemia, solid tumors of childhood, lymphocytic lymphonas, cancer of the bladder, cancer of the kidney or ureter, or neoplasms of the central nervous system, therefore, it can be used as the therapeutics for treating and preventing cancer diseases.

摘要翻译： 本发明涉及具有抗癌活性的2-氧代杂环化合物及其制备方法的新用途以及包含其的药物组合物。 本发明提供了用于预防和治疗包括肺癌，骨癌，胰腺癌，皮肤癌，头颈癌，皮肤或眼内黑素瘤，子宫癌，卵巢癌，直肠癌或癌症的癌症疾病的药物组合物 肛门区域，胃癌，结肠癌，乳腺癌，妇科肿瘤，霍奇金病，食道癌，小肠癌，内分泌系统癌，软组织肉瘤，尿道癌，阴茎癌 ，前列腺癌，慢性或急性白血病，儿童实体瘤，淋巴细胞淋巴管，膀胱癌，肾或输尿管癌，或中枢神经系统肿瘤，因此可用作治疗和预防的治疗剂 癌症疾病

公开(公告)号：US20060094790A1

公开(公告)日：2006-05-04

申请号：US11260745

申请日：2005-10-27

申请人： Byeong-Deog Park ,  Jong-Kyung Youm ,  Hyung-Sub Gwak ,  Mi-Jong Kwon ,  Yong-Moon Lee ,  Yoo-Hun Kim ,  Hwan-Mook Kim ,  Song-Kyu Park ,  Ki-Ho Lee ,  Chang-Woo Lee ,  Myong-Lyoll Lee

发明人： Byeong-Deog Park ,  Jong-Kyung Youm ,  Hyung-Sub Gwak ,  Mi-Jong Kwon ,  Yong-Moon Lee ,  Yoo-Hun Kim ,  Hwan-Mook Kim ,  Song-Kyu Park ,  Ki-Ho Lee ,  Chang-Woo Lee ,  Myong-Lyoll Lee

IPC分类号： A61K31/16

CPC分类号： A61K31/16 ,  A61K8/68 ,  A61Q19/08 ,  C07C235/08 ,  C07C235/74

摘要： Disclosed is a non-natural ceramide compound effective for a sphingosine kinase activator, and thus useful for a skin disease treating agent. The sphingosine kinase activator enhances production of sphingosine-1-phosphate to show various physiological activities provided by sphingosine-1-phosphate. The physiological activities include the effects of: controlling multiplication and differentiation of keratinocytes, multiplication of fibroblasts and collagen synthesis, resulting in treatment of wounds, recovery of damaged skin functions in atopic dermatitis and psoriasis; inhibiting wrinkles and skin irritation caused by ultraviolet rays, followed by improvement of wrinkles and inhibition of skin aging; and reducing skin atrophy, which is a typical side effect of local application steroids. Therefore, the sphingosine kinase activator is useful for a skin disease treating agent for treating skin wounds, wrinkles, atopic dermatitis, eczema, psoriasis, or skin atrophy caused by side effects of local application steroids.

摘要翻译： 公开了对鞘氨醇激酶活化剂有效的非天然神经酰胺化合物，因此可用于皮肤疾病治疗剂。 鞘氨醇激酶激活剂增强了鞘氨醇-1-磷酸的产生，以显示由鞘氨醇-1-磷酸提供的各种生理活性。 生理活动包括：控制角质形成细胞的增殖和分化，成纤维细胞的增殖和胶原合成，导致伤口的治疗，恢复特应性皮炎和牛皮癣损伤的皮肤功能; 抑制由紫外线引起的皱纹和皮肤刺激，随后改善皱纹和抑制皮肤老化; 并减少皮肤萎缩，这是局部应用类固醇的典型副作用。 因此，鞘氨醇激酶激活剂可用于皮肤疾病治疗剂，用于治疗由局部应用类固醇的副作用引起的皮肤伤口，皱纹，特应性皮炎，湿疹，牛皮癣或皮肤萎缩。

公开(公告)号：US06790830B2

公开(公告)日：2004-09-14

申请号：US10141723

申请日：2002-05-09

申请人： Sang-Nyun Kim ,  Ho-Jeong Ahn ,  Chang-Woo Lee ,  Min-Ho Lee ,  Jung-Hun Kim ,  Jong-Il Kim ,  Seung-Jin Kim ,  Ho-Song Cho ,  Heon-Sik Lee ,  Hyung-Jin Kim

发明人： Sang-Nyun Kim ,  Ho-Jeong Ahn ,  Chang-Woo Lee ,  Min-Ho Lee ,  Jung-Hun Kim ,  Jong-Il Kim ,  Seung-Jin Kim ,  Ho-Song Cho ,  Heon-Sik Lee ,  Hyung-Jin Kim

IPC分类号： A61K3813

CPC分类号： A61K38/13 ,  A61K8/64 ,  A61Q5/12 ,  A61Q7/00 ,  C07K7/645

摘要： The present invention discloses a hair growth promoting agent comprising a cyclosporin derivative as an active ingredient, and more particularly, a hair growth promoting agent comprising a cyclosporin A derivative substituted in the 3-position as an active ingredient.

摘要翻译： 本发明公开了一种包含环孢菌素衍生物作为活性成分的毛发生长促进剂，更具体地说，涉及一种包含以3位取代的环孢菌素A衍生物作为活性成分的毛发生长促进剂。

公开(公告)号：US06377293B2

公开(公告)日：2002-04-23

申请号：US09345762

申请日：1999-07-01

申请人： Byeong-Cheon Koh ,  Chang-Woo Lee ,  Young-Chul Kim

发明人： Byeong-Cheon Koh ,  Chang-Woo Lee ,  Young-Chul Kim

IPC分类号： B41J2700

CPC分类号： G02B26/122 ,  F16C32/0431

摘要： A scanning unit of a laser printer in which a cover is provided on a scanning motor so that the scanning motor is isolated from an outside and an inner portion of the cover is maintained in a vacuum state, and in which the scanning motor is provided with a magnetic bearing having a repulsive force in thrust and radial directions, and a magnetic bearing apparatus used in the scanning unit, whereby the noise is lowered and the structure of the scanning unit can be simplified.

摘要翻译： 一种激光打印机的扫描单元，其中在扫描电机上设置盖，使得扫描马达与外部隔离，并且盖的内部保持在真空状态，并且其中扫描马达设置有 具有推力和径向方向的排斥力的磁性轴承，以及在扫描单元中使用的磁轴承装置，由此噪声降低，并且可以简化扫描单元的结构。

公开(公告)号：US20130256911A1

公开(公告)日：2013-10-03

申请号：US13391063

申请日：2010-02-22

申请人： Jae-Hak Lee ,  Chang-Woo Lee ,  Joon-Yub Song ,  Tae-Ho Ha

发明人： Jae-Hak Lee ,  Chang-Woo Lee ,  Joon-Yub Song ,  Tae-Ho Ha

IPC分类号： H01L23/488 ,  H01L21/50

CPC分类号： H01L23/488 ,  H01L21/50 ,  H01L24/26 ,  H01L24/29 ,  H01L24/32 ,  H01L24/48 ,  H01L24/73 ,  H01L24/92 ,  H01L25/0657 ,  H01L25/50 ,  H01L2224/04042 ,  H01L2224/26145 ,  H01L2224/27013 ,  H01L2224/29139 ,  H01L2224/2919 ,  H01L2224/29191 ,  H01L2224/32145 ,  H01L2224/48091 ,  H01L2224/73215 ,  H01L2224/73265 ,  H01L2224/82143 ,  H01L2224/83002 ,  H01L2224/83051 ,  H01L2224/83143 ,  H01L2224/83192 ,  H01L2224/9205 ,  H01L2224/92147 ,  H01L2225/0651 ,  H01L2225/06562 ,  H01L2225/06593 ,  H01L2924/00014 ,  H01L2924/10253 ,  H01L2924/30107 ,  H01L2924/00 ,  H01L2224/45099 ,  H01L2224/45015 ,  H01L2924/207

摘要： The present invention relates to a semiconductor chip stack package and a manufacturing method thereof, and more particularly, to a semiconductor chip stack package and a manufacturing method thereof in which a plurality of chips can be rapidly arranged and bonded without a precise device or operation so as to improve productivity

摘要翻译： 半导体芯片堆叠封装及其制造方法技术领域本发明涉及一种半导体芯片堆叠封装及其制造方法，更具体地，涉及一种半导体芯片堆叠封装及其制造方法，其中可以在没有精确的装置或操作的情况下快速地布置和粘合多个芯片 以提高生产率

公开(公告)号：US20120196831A1

公开(公告)日：2012-08-02

申请号：US13500843

申请日：2010-10-08

申请人： Gyoon-Hee Han ,  Yong Seok Choi ,  Sang-Bae Han ,  Jong-Ho Lee ,  Hwan-Mook Kim ,  Song-Kyu Park ,  Ki-Ho Lee ,  Jong-Soon Kang ,  Ki-Hoon Lee ,  Chang-Woo Lee

发明人： Gyoon-Hee Han ,  Yong Seok Choi ,  Sang-Bae Han ,  Jong-Ho Lee ,  Hwan-Mook Kim ,  Song-Kyu Park ,  Ki-Ho Lee ,  Jong-Soon Kang ,  Ki-Hoon Lee ,  Chang-Woo Lee

IPC分类号： A61K31/724 ,  A61P3/04 ,  A61P9/12 ,  A61P3/10 ,  A61P9/10 ,  A61P9/00 ,  A61P25/00 ,  C08B37/16 ,  A61P3/06

CPC分类号： A61K31/724 ,  A23L29/35 ,  A23L33/10 ,  A23V2002/00 ,  A23V2200/328 ,  A23V2200/332 ,  A23V2250/5112

摘要： There is provided a composition for preventing and treating obesity including high water-soluble β-cyclodextrin derivatives as an effective component. Specifically, the composition including the high water-soluble β-cyclodextrin derivatives, especially, 2-hydroxypropyl-β-cyclodextrin (HP-β-CD, HPBCD) has effects on suppressing an increase in body weight induced by a high fat diet, suppressing appetite through decreasing an amount of dietary intake, decreasing body fat, decreasing liver weight, and significantly decreasing a sharp increase of blood sugar induced by intaking glucose and maltose on an empty stomach so that it can be useful for preventing and treating obesity, preventing and treating various diseases induced by obesity, and suppressing a sharp increase of blood sugar after dinner.

摘要翻译： 提供了用于预防和治疗包括高水溶性和环糊精衍生物作为有效成分的肥胖的组合物。 具体地说，包含高水溶性β-环糊精衍生物，特别是2-羟丙基 - 环糊精（HP-＆bgr-CD，HPBCD）的组合物具有抑制高脂肪引起的体重增加的作用 饮食，通过减少饮食摄入量，减少身体脂肪，减少肝脏重量并显着降低通过在空腹进食葡萄糖和麦芽糖而引起的血糖的急剧增加，从而抑制食欲，从而可用于预防和治疗肥胖 预防和治疗肥胖引起的各种疾病，抑制晚饭后血糖急剧增加。

公开(公告)号：US20110006036A1

公开(公告)日：2011-01-13

申请号：US12922090

申请日：2009-03-12

申请人： Chang-Woo Lee ,  Dong-Seob Kim ,  Sun Wei ,  Woon-Bong Hwang

发明人： Chang-Woo Lee ,  Dong-Seob Kim ,  Sun Wei ,  Woon-Bong Hwang

IPC分类号： B01D67/00 ,  B29C71/04

CPC分类号： B01D67/0034 ,  B01D2325/08 ,  B01D2325/36 ,  B01D2325/38

摘要： A method for fabricating a membrane is disclosed, to provide both hydrophilicity and hydrophobicity to predetermined positions of a surface of a single membrane. The method for fabricating a membrane includes: preparing a template with nano-scale holes formed on its outer surface; coating a polymer material on a predetermined pattern region of the outer surface of the template; attaching a hydrophilic film on the outer surface of the template; and removing the template from the hydrophilic film.

摘要翻译： 公开了制造膜的方法，以提供单一膜表面的预定位置的亲水性和疏水性。 制造膜的方法包括：在其外表面上制备具有纳米级孔的模板; 在所述模板的外表面的预定图案区域上涂覆聚合物材料; 在模板的外表面上附着亲水膜; 并从亲水膜去除模板。

公开(公告)号：US07708905B2

公开(公告)日：2010-05-04

申请号：US10594804

申请日：2004-05-25

申请人： Chang-Woo Lee ,  Wan-Goo Cho ,  Jin-Young Hyun ,  Kyung-Hee Oh

发明人： Chang-Woo Lee ,  Wan-Goo Cho ,  Jin-Young Hyun ,  Kyung-Hee Oh

IPC分类号： C11D3/39 ,  C11D7/54

CPC分类号： C07C303/32 ,  C07C68/02 ,  C07C303/22 ,  C07C69/96 ,  C07C309/42

摘要： A method for preparing an ester bleach activator compound is disclosed. The method includes (A) preparing fatty acid monoester; (B) making chloroformate by reacting the fatty acid monoester with at least one selected from the group consisting of phosgene, diphosgene and triphosgene in the presence of base; and (C) reacting the chloroformate with hydroxybenzene, its derivatives, or its salts in solvent. According to the method, the ester bleach activator compound can be made in a simple and economic way.

摘要翻译： 公开了一种制备酯漂白活化剂化合物的方法。 该方法包括（A）制备脂肪酸单酯; （B）在碱存在下使脂肪酸单酯与选自光气，双光气和三光气中的至少一种反应制备氯甲酸酯; 和（C）使氯甲酸酯与羟基苯，其衍生物或其盐在溶剂中反应。 根据该方法，可以简单经济地制备酯漂白活化剂。

公开(公告)号：US20090105495A1

公开(公告)日：2009-04-23

申请号：US10594804

申请日：2004-05-25

申请人： Chang-Woo Lee ,  Wan-Goo Cho ,  Jin-Young Hyun ,  Kyung-Hee Oh

发明人： Chang-Woo Lee ,  Wan-Goo Cho ,  Jin-Young Hyun ,  Kyung-Hee Oh

IPC分类号： C07C68/02

CPC分类号： C07C303/32 ,  C07C68/02 ,  C07C303/22 ,  C07C69/96 ,  C07C309/42

摘要： A method for preparing an ester bleach activator compound is disclosed. The method includes (A) preparing fatty acid monoester; (B) making chloroformate by reacting the fatty acid monoester with at least one selected from the group consisting of phosgene, diphosgene and triphosgene in the presence of base; and (C) reacting the chloroformate with hydroxybenzene, its derivatives, or its salts in solvent. According to the method, the ester bleach activator compound can be made in a simple and economic way.

摘要翻译： 公开了一种制备酯漂白活化剂化合物的方法。 该方法包括（A）制备脂肪酸单酯; （B）在碱存在下使脂肪酸单酯与选自光气，双光气和三光气中的至少一种反应制备氯甲酸酯; 和（C）使氯甲酸酯与羟基苯，其衍生物或其盐在溶剂中反应。 根据该方法，可以简单经济地制备酯漂白活化剂。

公开(公告)号：US20080245774A1

公开(公告)日：2008-10-09

申请号：US12157209

申请日：2008-06-09

申请人： Cheol-Hee Kim ,  Nam-Hyun Kang ,  Jun-Ki Kim ,  Chang-Woo Lee

发明人： Cheol-Hee Kim ,  Nam-Hyun Kang ,  Jun-Ki Kim ,  Chang-Woo Lee

IPC分类号： B23K26/00 ,  B23K9/00

CPC分类号： B23K28/02 ,  B23K26/0093 ,  B23K26/348

摘要： The present invention relates to a laser-rotating arc hybrid welding system and a welding method using the system. The laser-rotating arc hybrid welding system of the present invention includes an arc discharge unit (2) for generating arc discharge along an area to be welded. A laser generation unit (4) radiates laser light onto the area to be welded. A rotating device (24) rotates the arc discharge unit (2). In the welding method using the laser-rotating arc hybrid welding system, a plurality of parent metals is aligned with a welding location. A laser-rotating arc hybrid welding system is located with respect to an area to be welded, arc discharge is generated while an arc discharge unit is rotated at a predetermined turning radius, and laser light is subsequently radiated using a laser generation unit.

摘要翻译： 本发明涉及激光旋转电弧复合焊接系统和使用该系统的焊接方法。 本发明的激光旋转电弧复合焊接系统包括：沿着待焊接区域产生电弧放电的电弧放电单元（2）。 激光产生单元（4）将激光照射到待焊接的区域上。 旋转装置（24）使电弧放电单元（2）旋转。 在使用激光旋转电弧复合焊接系统的焊接方法中，多个母体金属与焊接位置对准。 激光旋转电弧复合焊接系统相对于待焊接的区域定位，在电弧放电单元以预定转动半径旋转时产生电弧放电，并且随后使用激光产生单元辐射激光。