公开(公告)号：US20090112185A1

公开(公告)日：2009-04-30

申请号：US12261450

申请日：2008-10-30

申请人： Peter Krulevitch ,  Frank Cichocki ,  Lorin P. Olson

发明人： Peter Krulevitch ,  Frank Cichocki ,  Lorin P. Olson

IPC分类号： A61M25/00

CPC分类号： A61M5/158 ,  A61M5/3286 ,  A61M5/3287 ,  A61M5/329 ,  A61M25/00 ,  A61M25/0068 ,  A61M2005/1585 ,  A61M2005/1587 ,  A61M2205/0266

摘要： A medical device includes a medical device flexible conduit that has an elongated Nitinol strip with a distal end, a proximal end, a longitudinal axis running from the distal end to the proximal end, a sharp head extending from the distal end, and a channel etched therein. Moreover, the channel is dispositioned along the longitudinal axis. The medical device flexible conduit also has a flexible tube at least partially jacketing the elongated Nitinol strip between the distal end and the proximal end, with the channel and the flexible tube defining a conduit. The medical device also includes an insertion mechanism configured to insert a portion of the flexible conduit, including the sharp head, into a user's target site such that the conduit provides fluid communication to the target site.

摘要翻译： 医疗装置包括医疗装置柔性导管，其具有细长的镍钛诺带，其具有远端，近端，从远端延伸到近端的纵向轴线，从远端延伸的尖头，以及蚀刻的通道 其中。 此外，通道沿着纵向轴线布置。 医疗器械柔性导管还具有柔性管，其至少部分地将细长的镍钛诺带夹在远端和近端之间，通道和柔性管限定导管。 该医疗装置还包括插入机构，该插入机构构造成将包括尖头的柔性导管的一部分插入使用者的目标部位，使得导管向目标部位提供流体连通。

公开(公告)号：US20090112155A1

公开(公告)日：2009-04-30

申请号：US12261426

申请日：2008-10-30

申请人： Mitch Zhao ,  Peter Krulevitch ,  David Knight ,  Anthony Lam ,  Sean O'Connor

发明人： Mitch Zhao ,  Peter Krulevitch ,  David Knight ,  Anthony Lam ,  Sean O'Connor

IPC分类号： A61M5/152 ,  F04B49/00

CPC分类号： A61M5/14212 ,  A61M5/14224 ,  A61M5/16831 ,  A61M2205/0294 ,  F04B43/02 ,  F04B43/043 ,  F04B43/046

摘要： The invention relates to micropumps for infusing fluids. More specifically, the present disclosure describes and illustrates a micropump design that may be useful for infusing insulin into a diabetic patient. The disclosed design employs a pump chamber that has a diaphragm and a plurality of check valves that are configured to avoid leakage from the reservoir through the pump engine and into an infusion device and, also, to ensure the complete, accurate evacuation of the pump chamber.

摘要翻译： 本发明涉及用于输注流体的微型泵。 更具体地，本公开描述并示出了可用于将胰岛素注入糖尿病患者的微型泵设计。 所公开的设计采用具有隔膜和多个止回阀的泵室，所述多个止回阀被构造成避免从储存器通过泵发动机泄漏并进入输液装置，并且还确保泵室的完全，精确的排空 。

公开(公告)号：US20060113537A1

公开(公告)日：2006-06-01

申请号：US11326967

申请日：2006-01-05

申请人： Peter Krulevitch ,  Mariam Maghribi ,  William Benett ,  Julie Hamilton ,  Klint Rose ,  James Davidson ,  Mark Strauch

发明人： Peter Krulevitch ,  Mariam Maghribi ,  William Benett ,  Julie Hamilton ,  Klint Rose ,  James Davidson ,  Mark Strauch

IPC分类号： H01L31/0376

CPC分类号： H01L25/165 ,  B81C1/0023 ,  H01L21/6835 ,  H01L31/048 ,  H01L31/0543 ,  H01L2221/68345 ,  H01L2924/0002 ,  H01L2924/09701 ,  H01L2924/19041 ,  H01L2924/19105 ,  Y02E10/52 ,  H01L2924/00

摘要： A peel and stick electronic system comprises a silicone body, and at least one electronic unit operatively connected to the silicone body. The electronic system is produce by providing a silicone layer on a substrate, providing a metal layer on the silicone layer, and providing at least one electronic unit connected to the metal layer.

公开(公告)号：US20160089503A1

公开(公告)日：2016-03-31

申请号：US14959701

申请日：2015-12-04

申请人： Lorin Olson ,  Vaclav Vojan ,  Juergen Ernst Pfrang ,  Peter Krulevitch ,  Jingli Wang ,  Nicholas Foley ,  Mingqi Zhao ,  Paul Tashjian

发明人： Lorin Olson ,  Vaclav Vojan ,  Juergen Ernst Pfrang ,  Peter Krulevitch ,  Jingli Wang ,  Nicholas Foley ,  Mingqi Zhao ,  Paul Tashjian

IPC分类号： A61M5/32 ,  A61M5/315 ,  A61M5/50 ,  A61M5/31

CPC分类号： A61M5/326 ,  A61M5/20 ,  A61M5/2033 ,  A61M5/2046 ,  A61M5/2053 ,  A61M5/3129 ,  A61M5/315 ,  A61M5/31511 ,  A61M5/3157 ,  A61M5/3204 ,  A61M5/3213 ,  A61M5/3243 ,  A61M5/3287 ,  A61M5/50 ,  A61M5/5086 ,  A61M2005/2013 ,  A61M2005/2026 ,  A61M2005/2073 ,  A61M2005/208 ,  A61M2005/3123 ,  A61M2005/3125 ,  A61M2005/3126 ,  A61M2005/3247 ,  A61M2205/581 ,  A61M2205/582 ,  A61M2205/583 ,  A61M2205/584 ,  A61M2205/586

摘要： A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position.

公开(公告)号：US07944366B2

公开(公告)日：2011-05-17

申请号：US11532691

申请日：2006-09-18

申请人： Peter Krulevitch ,  Sebastian Bohm ,  Mingqi Zhao ,  Deon Anex

发明人： Peter Krulevitch ,  Sebastian Bohm ,  Mingqi Zhao ,  Deon Anex

IPC分类号： G08B21/00 ,  A61M31/00 ,  A61M37/00 ,  A61M1/00 ,  G01F25/00 ,  B23H11/00 ,  G01R31/00

CPC分类号： A61M5/14244 ,  A61M5/14248 ,  A61M5/1452 ,  A61M5/16831 ,  A61M5/172 ,  A61M2005/14513 ,  A61M2205/3317 ,  A61M2205/3389

摘要： Systems and methods of detecting occlusions and fluid-loss conditions (e.g., disconnects and/or leakages) in an infusion pump are discussed. For example, electrokinetic infusion pumps may develop an occlusion in the fluid flow path, which can disrupt control of fluid dispersed from the pump. As well, an infusion set disconnect can also result in a fluid-loss that can be disruptive. Such disruptions can be troublesome to systems that control the infusion pump, such as closed loop controllers. Accordingly, systems and methods described herein can be used to detect such occlusions and fluid-loss conditions during infusion pump operation. For example, a position sensor can be used to monitor fluid flow from the infusion pump, with the measurement being compared with an expected value to detect an occlusion or fluid-loss condition. Other algorithms for utilizing the position sensor are also described.

摘要翻译： 讨论了检测输液泵中的闭塞和流体损失状况（例如断开和/或泄漏）的系统和方法。 例如，电动输液泵可能在流体流动路径中产生闭塞，这可能破坏从泵分散的流体的控制。 同样，输液器断开也可能导致流体损失，这可能是破坏性的。 对于控制输液泵的系统，例如闭环控制器，这种中断可能是麻烦的。 因此，本文所述的系统和方法可用于在输注泵操作期间检测这种闭塞和流体损失状况。 例如，位置传感器可用于监测来自输注泵的流体流动，其中测量值与预期值进行比较以检测堵塞或流体损失状况。 还描述了用于利用位置传感器的其它算法。

公开(公告)号：US20090149918A1

公开(公告)日：2009-06-11

申请号：US11951376

申请日：2007-12-06

申请人： Peter Krulevitch ,  Michael R. Tracey ,  Stuart Wenzel

发明人： Peter Krulevitch ,  Michael R. Tracey ,  Stuart Wenzel

IPC分类号： A61N1/00

CPC分类号： A61N1/36 ,  A61N1/0551 ,  A61N1/3605 ,  A61N1/37229 ,  A61N1/3787

摘要： An antenna implantable through minimally invasive techniques, preferably comprising a coil with conductive probes is provided. The antenna is preferably superelastic nickel-titanium having an insulative coating. The antenna may conduct a signal originating from a device external to the body of the implantee, or from another implanted device connected to the antenna depending on whether the antenna is employed for sending, receiving, or transceiving signals. Signals may contain data, operational commands, and may be used to transfer power. The implantable antenna may be connected to another implanted device, such as a blood pressure monitor, or may be implanted as a stand-alone device for purposes such as stimulating tissue.

摘要翻译： 提供通过微创技术可植入的天线，优选地包括具有导电探针的线圈。 天线优选为具有绝缘涂层的超弹性镍钛。 根据天线是否用于发送，接收或收发信号，天线可以传送源自植入物体的外部的装置的信号，或者连接到天线的另一植入装置。 信号可能包含数据，操作命令，并可用于传输电力。 植入式天线可以连接到另一植入装置，例如血压监测器，或者可以作为独立装置植入，用于刺激组织等目的。

公开(公告)号：US20070128240A1

公开(公告)日：2007-06-07

申请号：US11294892

申请日：2005-12-06

申请人： Peter Krulevitch

发明人： Peter Krulevitch

IPC分类号： A61F2/06

CPC分类号： A61N1/375 ,  A61B2562/028 ,  A61M2205/0244 ,  A61N1/37205 ,  B82Y5/00

摘要： A compliant biocompatible packaging scheme, (i.e., coating) for implantable medical device, particularly implantable biomedical microsystems is provided. In accordance with the present invention, the compliant biocompatible coating includes an optional dielectric undercoating and an overcoat comprising a NiTi shape memory alloy.

摘要翻译： 提供了用于可植入医疗装置，特别是可植入的生物医学微系统的兼容的生物相容性包装方案（即，涂层）。 根据本发明，柔性生物相容性涂层包括任选的介电底涂层和包含NiTi形状记忆合金的外涂层。

公开(公告)号：US20070093753A1

公开(公告)日：2007-04-26

申请号：US11532726

申请日：2006-09-18

申请人： Peter Krulevitch ,  Sebastian Bohm ,  Mingqi Zhao ,  Deon Anex

发明人： Peter Krulevitch ,  Sebastian Bohm ,  Mingqi Zhao ,  Deon Anex

IPC分类号： A61M37/00 ,  A61K9/22

CPC分类号： A61M5/14244 ,  A61M5/14248 ,  A61M5/1452 ,  A61M5/16831 ,  A61M5/172 ,  A61M2005/14513 ,  A61M2205/3317 ,  A61M2205/3389

摘要： Systems and methods of detecting occlusions and fluid-loss conditions (e.g., disconnects and/or leakages) in an infusion pump are discussed. For example, electrokinetic infusion pumps may develop an occlusion in the fluid flow path, which can disrupt control of fluid dispersed from the pump. As well, an infusion set disconnect can also result in a fluid-loss that can be disruptive. Such disruptions can be troublesome to systems that control the infusion pump, such as closed loop controllers. Accordingly, systems and methods described herein can be used to detect such occlusions and fluid-loss conditions during infusion pump operation. For example, a position sensor can be used to monitor fluid flow from the infusion pump, with the measurement being compared with an expected value to detect an occlusion or fluid-loss condition. Other algorithms for utilizing the position sensor are also described.

摘要翻译： 讨论了检测输液泵中的闭塞和流体损失状况（例如断开和/或泄漏）的系统和方法。 例如，电动输液泵可能在流体流动路径中产生阻塞，这可能破坏从泵分散的流体的控制。 同样，输液器断开也可能导致流体损失，这可能是破坏性的。 对于控制输液泵的系统，例如闭环控制器，这种中断可能是麻烦的。 因此，本文所述的系统和方法可用于在输注泵操作期间检测这种闭塞和流体损失状况。 例如，位置传感器可用于监测来自输注泵的流体流动，其中测量值与预期值进行比较以检测堵塞或流体损失状况。 还描述了用于利用位置传感器的其它算法。

公开(公告)号：US20070093752A1

公开(公告)日：2007-04-26

申请号：US11532631

申请日：2006-09-18

申请人： Mingqi Zhao ,  Peter Krulevitch

发明人： Mingqi Zhao ,  Peter Krulevitch

IPC分类号： A61M37/00 ,  A61M1/00

CPC分类号： A61M5/14244 ,  A61M5/1452 ,  A61M5/172 ,  A61M2005/14513 ,  A61M2205/3317 ,  A61M2205/702

摘要： An infusion pump (e.g., an electrokinetic infusion pump) includes an infusion pump module and an engine that can drive a moveable piston non-mechanically. In addition, the infusion pump module includes a position detector configured for sensing a dispensing state of the infusion pump module. Such information can be utilized in a control scheme to control fluid displacement within and out of the pump. Descriptions of different types of position detectors, such as magnetic sensors (e.g., an anisotropic magnetic resistive sensor), and their implementation in detecting infusion pump fluid displacement are described.

摘要翻译： 输液泵（例如，电动输液泵）包括可以非机械地驱动可移动活塞的输液泵模块和发动机。 此外，输液泵模块包括位置检测器，其被配置为感测输注泵模块的分配状态。 这样的信息可以用于控制方案中以控制泵内和泵外的流体位移。 描述不同类型的位置检测器，例如磁传感器（例如，各向异性磁阻传感器）及其在检测输液泵流体位移中的实现。

公开(公告)号：US20060052656A1

公开(公告)日：2006-03-09

申请号：US10938816

申请日：2004-09-09

申请人： Mariam Maghribi ,  Peter Krulevitch ,  James Davidson ,  Julie Hamilton

发明人： Mariam Maghribi ,  Peter Krulevitch ,  James Davidson ,  Julie Hamilton

IPC分类号： A61N2/00

CPC分类号： A61N1/0541 ,  A61N1/0543

摘要： A system for movement in a body and performing a function on the body. The system comprises a polymer body portion, an electronic unit carried by the polymer body portion, a circuit in the polymer body portion operatively connected to the electronic unit, pieces in the polymer body portion, and a system for controlling movement of the polymer body portion utilizing magnetic forces controlling movement of the pieces. The system utilizes magnetic guidance to control movement of a polymer body portion.

摘要翻译： 用于身体运动并在身体上执行功能的系统。 该系统包括聚合物主体部分，由聚合物主体部分承载的电子单元，可操作地连接到电子单元的聚合物主体部分中的电路，聚合物主体部分中的片，以及用于控制聚合物主体部分的运动的系统 利用磁力控制片的运动。 该系统利用磁引导来控制聚合物主体部分的运动。