摘要:
The present invention relates to the efficient expression of HIV polypeptides in a variety of cell types, including, but not limited to, mammalian, insect, and plant cells. Synthetic expression cassettes encoding the HIV Gag-containing polypeptides are described, as are uses of the expression cassettes in applications including DNA immunization, generation of packaging cell lines, and production of Env-, tat- or Gag-containing proteins. The invention provides methods of producing Virus-Like Particles (VLPs), as well as, uses of the VLPs including, but not limited to, vehicles for the presentation of antigens and stimulation of immune response in subjects to whom the VLPs are administered.
摘要:
This invention provides a system for performing PCR, and real time PCR in particular with great speed and specificity. The system employs a heat block containing a liquid composition to rapidly transfer heat to and from reaction vessels. The system makes use of the reflective properties of the liquid metal to reflect signal from the PCR into the vessel and out the top. In this way, the signal can be measured by an optical assembly in real time without removing the vessels from the heat block.
摘要:
The invention relates to articles such as protective films and displays having a fluorochemical surface layer comprising an antistatic agent and the reaction products of at least one fluoropolyether (meth)acryl compound and at least 50 wt-% of non-fluorinated crosslinking agent(s).
摘要:
An economic, optically transmissive, stain and ink repellent, durable low refractive index fluoropolymer composition for use in an antireflection film or coupled to an optical display. In one aspect of the invention, the composition is formed from the reaction product of a fluoropolymer or reactive fluoropolymer, an amino silane ester coupling agent or ester equivalent, a multi-olefinic crosslinker, and optional surface modified inorganic particles or sol gel precursors.
摘要:
An economic, optically transmissive, stain and ink repellent, durable low refractive index fluoropolymer composition for use in an antireflection film or coupled to an optical display. In one aspect of the invention, the composition is formed from the reaction product of a fluoropolymer, a C═C double bond group containing silane ester agent, and an optional multi-olefinic crosslinker. In another aspect of the invention, the composition further includes surface modified inorganic nanoparticles. In another aspect, the multi-olefinic crosslinker is an alkoxysilyl-containing multi-olefinic crosslinker.
摘要:
A tailgate assembly adapted to be mounted along an open edge of a vehicle's load-carrying bed is provided. The tailgate is able to alternatively pivot about (1) an axis generally parallel with a bottom edge of the tailgate for movement between a closed position and a folded-open position and (2) an axis generally parallel with a lateral edge of the tailgate for movement between the closed position and a swing-open position. The tailgate assembly includes a stamped sheet metal frame having a reinforced cross-sectional shape with an inner side facing an associated vehicle's load-carrying bed and an outer side opposite the inner side. The tailgate assembly further includes a skin attached to the outer side of the frame.
摘要:
A stackable network unit comprises a ‘down’ port and an ‘up’ port, an arbitration path for data packets from the down port to the up port, a repeat path for data packets from the up port to the down port, a link detector for detecting tile absence of another operative unit connected to the down port to cause data packets on the return pat to bypass the down port and proceed on the arbitration path and for detecting the absence of another operative unit connected to the up port to cause data packets on the arbitration path to bypass the up port and proceed on the repeat path.
摘要:
A communications apparatus comprising a plurality of communication devices each having a plurality of ports and a data bus interconnecting the plurality of units, wherein each device is provided with means enabling the device to detect automatically its position on the data bus.
摘要:
A system and method for manufacturing objects in an automated fashion to improve the accessibility and effectiveness of manufacturing technologies. The system may be comprised of one or more web-accessible servers, one or more clients that may communicate with the server, and one or more manufacturing apparatuses that may communicate with one or more clients or servers. The server turns designs into manufacturing instructions using user-specified settings and databases of manufacturing parameters for particular apparatuses and/or manufacturing methods. The system may facilitate communication and revision of designs, manufacturing parameters, or manufacturing instructions between the user and the owner or operator of the manufacturing apparatus. The client may facilitate communication between the server and manufacturing apparatus, may monitor the manufacturing apparatus, and may be physically internal or external to the apparatus.
摘要:
The present invention relates to the efficient expression of HIV polypeptides in a variety of cell types, including, but not limited to, mammalian, insect, and plant cells. Synthetic expression cassettes encoding the HIV Gag-containing polypeptides are described, as are uses of the expression cassettes in applications including DNA immunization, generation of packaging cell lines, and production of Env-, tat- or Gag-containing proteins. The invention provides methods of producing Virus-Like Particles (VLPs), as well as, uses of the VLPs including, but not limited to, vehicles for the presentation of antigens and stimulation of immune response in subjects to whom the VLPs are administered.