-
公开(公告)号：US4119737A
公开(公告)日：1978-10-10
申请号：US762534
申请日：1977-01-26
IPC分类号： A23L27/20 , A23L27/26 , C07D307/18 , C07D307/30 , C07D307/64 , C07D333/00 , C07D333/34 , C07D409/12 , A23L1/231
CPC分类号： C07D307/18 , A23L27/2052 , C07D307/30 , C07D307/64 , C07D333/34
摘要： Novel thioether compounds are disclosed which are useful as flavoring materials to enhance or impart meat-like flavors to foodstuffs. These compounds have the general formula ##STR1## where X can be, under specified conditions, --CH.sub.2 --, oxygen, or sulfur, Y can be oxygen or sulfur and R.sub.1, R.sub.2, R.sub.3, and R.sub.4 are hydrogen or 1 to 3 carbon alkyl groups.
摘要翻译： 公开了新的硫醚化合物，其可用作调味材料以增强或赋予肉类风味食品。 这些化合物具有通式
，其中X在规定条件下可以是-CH 2 - ，氧或硫，Y可以是氧或硫，并且R 1，R 2，R 3和R 4是氢或1至3个碳烷基 团体 -
公开(公告)号：US4080367A
公开(公告)日：1978-03-21
申请号：US745311
申请日：1976-11-26
IPC分类号： A23L27/20 , C07D307/18 , C07D307/20 , C07D307/30 , C07D307/32 , C07D307/58 , C07D307/60 , C07D307/64 , C07D333/32 , C11B9/00
CPC分类号： C07D307/18 , A23L27/2052 , C07D307/20 , C07D307/30 , C07D307/32 , C07D307/58 , C07D307/60 , C07D307/64 , C07D333/32 , C11B9/008 , C11B9/0084
摘要： Novel sulphur containing food flavor substances are provided containing an oxygen or sulphur atom in a five or six membered ring structure, one alkyl or hydroxy alkyl substituent at at least either of the carbon atoms adjacent to the hetero atom and having at least one sulphur or oxygen atom attached to another carbon atom of the ring structure.
摘要翻译： 提供含有五元或六元环结构中的氧或硫原子的新型含硫食品香料物质，在与杂原子相邻的至少一个碳原子上具有一个烷基或羟基烷基取代基并且具有至少一个硫或氧 原子连接到环结构的另一个碳原子。
-
23.发明授权
公开(公告)号：US3983134A
公开(公告)日：1976-09-28
申请号：US602178
申请日：1975-08-05
IPC分类号： C07D307/22 , C07D307/30 , C07D333/36 , C07D333/48 , C07D491/04 , C07D491/048 , C07D495/04 , C07D49/34
CPC分类号： C07D491/04 , C07D307/22 , C07D307/30 , C07D333/36 , C07D333/48 , C07D495/04
摘要： Ureylenethiophanes and their related compounds of the formula: ##SPC1##Having a cis-configuration on the ureylene or thioureylene juncture, which are useful as the intermediates in the synthesis of biologically active biotin and its related compounds, can be produced selectively by reacting the corresponding compounds of the formula: ##SPC2##With isocyanates or isothiocyanates wherein R is a hydrogen atom, an alkyl group or an aralkyl group, R.sub.1 and R.sub.2 are each a hydrogen atom or an aliphatic hydrocarbon group bearing or not a carboxyl group or any other group convertible thereto at the terminal position, X is a halogen atom, Y is an oxygen atom or a sulfur atom and Z is an oxygen atom, a sulfur atom, a sulfinyl group or a sulfonyl group.
摘要翻译： 尿素二乙炔及其相关化合物的分子式如下：
-
公开(公告)号：US3455964A
公开(公告)日：1969-07-15
申请号：US3455964D
申请日：1966-06-27
申请人： SHELL OIL CO
发明人： PAYNE GEORGE B
IPC分类号： C07D307/28 , C07D307/30 , C07D5/10 , C08H17/22
CPC分类号： C07D307/28 , C07D307/30
-
公开(公告)号：US20240124385A1
公开(公告)日：2024-04-18
申请号：US18516407
申请日：2023-11-21
申请人： CORSAIR PHARMA, INC.
IPC分类号： C07C69/734 , A61K9/70 , C07C53/136 , C07C59/11 , C07C59/13 , C07C69/28 , C07C69/675 , C07C69/68 , C07C69/708 , C07C69/712 , C07C69/74 , C07C69/75 , C07C69/96 , C07D305/08 , C07D307/24 , C07D307/30 , C07D309/08
CPC分类号： C07C69/734 , A61K9/7023 , C07C53/136 , C07C59/11 , C07C59/13 , C07C69/28 , C07C69/675 , C07C69/68 , C07C69/708 , C07C69/712 , C07C69/74 , C07C69/75 , C07C69/96 , C07D305/08 , C07D307/24 , C07D307/30 , C07D309/08 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2603/14
摘要： The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
-
公开(公告)号：US11339146B2
公开(公告)日：2022-05-24
申请号：US16877291
申请日：2020-05-18
发明人： Jean-Simon Diallo , Christopher Noyce Boddy , Mark Dornan , Ramya Krishnan , Rozanne Arulanandam , Fabrice Le Boeuf , Jeffrey Smith , Andrew Macklin
IPC分类号： A61K31/501 , C07D413/06 , C07D237/14 , C07D207/38 , C07D307/60 , C07D307/66 , C07D401/06 , C07D403/06 , C07D405/04 , C07D405/12 , C07D409/06 , C07D307/30 , C07D307/58 , C07D405/06 , A61K45/06 , C12N7/00 , C07D207/36 , C07D207/456 , C07D317/64 , C07D417/06 , C07D471/04 , A61P35/02 , C07D209/48 , C07D231/08 , A61K31/341
摘要： Provided are compounds of Formula (II) that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the antigen expression from a virus, gene or trans-gene expression from a virus, or virus protein expression in cells. Other uses, compositions and methods of using same are also provided.
-
公开(公告)号：US20200290032A1
公开(公告)日：2020-09-17
申请号：US16886418
申请日：2020-05-28
发明人： Claude GRISON , Vincent ESCANDE
IPC分类号： B01J31/22 , B01J37/06 , B01J37/08 , B01J37/00 , B01J23/34 , B01J37/36 , B09C1/10 , B01J23/889 , B01J37/14 , B01J37/30 , B01J37/34 , C07C1/20 , C07C5/367 , C07C45/29 , C07C49/807 , C07C67/307 , C07C211/50 , C07C245/08 , C07D213/80 , C07D307/30 , C07D307/68 , C07D401/04 , C07D403/14 , C07D407/04
摘要： Compositions of manganese accumulating plants.
-
28.发明授权公开(公告)号：US10702860B2
公开(公告)日：2020-07-07
申请号：US14416404
申请日：2013-07-23
发明人： Claude Grison , Vincent Escande
IPC分类号： B01J31/22 , B01J37/06 , B01J37/08 , B01J37/00 , B01J23/34 , B01J37/36 , B09C1/10 , B01J23/889 , B01J37/14 , B01J37/30 , B01J37/34 , C07C1/20 , C07C5/367 , C07C45/29 , C07C49/807 , C07C67/307 , C07C211/50 , C07C245/08 , C07D213/80 , C07D307/30 , C07D307/68 , C07D401/04 , C07D403/14 , C07D407/04
摘要： The use, after heat treatment, of manganese accumulating plants for carrying out chemical reactions.
-
公开(公告)号：US09701601B2
公开(公告)日：2017-07-11
申请号：US14401051
申请日：2012-11-20
发明人： Shengming Ma , Juntao Ye
IPC分类号： C07C29/17 , C07C311/16 , C07C33/03 , C07C33/12 , C07C67/343 , C07C29/00 , C07D307/30 , C07D307/28 , C07C33/14
CPC分类号： C07C29/17 , C07B2200/07 , C07C29/00 , C07C33/03 , C07C33/12 , C07C33/14 , C07C67/343 , C07C311/16 , C07C2601/08 , C07C2601/14 , C07D307/28 , C07D307/30 , C07C33/02 , C07C33/30 , C07C33/38 , C07C69/608
摘要： The present invention relates to an optically active axially chiral α-allenic alcohol, a synthesis method and use thereof. The invention relates to a method of preparing a highly optically active chiral α-allenic alcohol by using propargyl alcohol, aldehyde and chiral α,α-diphenyl-L-prolinol under the protection of tert-butyldimethylsilyl with an accelerant zinc bromide. The axially chiral α-allenic alcohol has the structural formula (I). The method of the present invention has the following advantages: the synthesis route is short, operations are simple, raw materials are readily available, separation and purification are convenient, the substrate has high universality, the total yield is high, and enantioselectivity and diastereoselectivity are high. The highly optically active axially chiral α-allenic alcohol synthesized by the method of the present invention can conveniently synthesize 2,5-dihydrofuran compounds having central chirality and complete chirality, and at the same time can further synthesize axially chiral allenic amine and allenic malonic ester compounds having complete chirality.
-
公开(公告)号：US09643911B2
公开(公告)日：2017-05-09
申请号：US14829180
申请日：2015-08-18
申请人： CORSAIR PHARMA, INC.
IPC分类号： C07C69/28 , C07C69/68 , C07C69/75 , C07C69/675 , C07C69/96 , C07D309/08 , C07C69/708 , C07C69/712 , C07D305/08 , C07D307/30 , A61K9/70 , C07C59/13 , C07C53/136 , C07C69/74 , C07C59/11
CPC分类号： C07C69/74 , A61K9/7023 , C07C53/136 , C07C59/11 , C07C59/13 , C07C69/28 , C07C69/675 , C07C69/68 , C07C69/708 , C07C69/712 , C07C69/75 , C07C69/96 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2603/14 , C07D305/08 , C07D307/24 , C07D307/30 , C07D309/08
摘要： The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
-
-
-
-
-
-
-
-
-
搜索结果
146 条记录 (耗时 0.017 秒)
