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    Photodefined aperture plate and method for producing the same
    31.
    发明授权
    Photodefined aperture plate and method for producing the same 有权

    公开(公告)号：US10662543B2

    公开(公告)日：2020-05-26

    申请号：US15001551

    申请日：2016-01-20

    Applicant: Stamford Devices Limited

    Inventor： Hong Xu

    IPC: C25D7/00 ,  B41J2/16 ,  C25D5/02 ,  C25D5/10 ,  C25D1/00 ,  B05B17/00 ,  C25D3/38 ,  C25D3/46 ,  C25D3/48 ,  C25D3/54 ,  C25D5/34 ,  C25D5/48 ,  C25D5/54

    Abstract: A method for manufacturing an aperture plate includes depositing a releasable seed layer above a substrate, applying a first patterned photolithography mask above the releasable seed layer, the first patterned photolithography mask having a negative pattern to a desired aperture pattern, electroplating a first material above the exposed portions of the releasable seed layer and defined by the first mask, applying a second photolithography mask above the first material, the second photolithography mask having a negative pattern to a first cavity, electroplating a second material above the exposed portions of the first material and defined by the second mask, removing both masks, and etching the releasable seed layer to release the first material and the second material. The first and second material form an aperture plate for use in aerosolizing a liquid. Other aperture plates and methods of producing aperture plates are described.

    HIGH FLOW NASAL THERAPY SYSTEM
    32.
    发明申请
    HIGH FLOW NASAL THERAPY SYSTEM 审中-公开

    公开(公告)号：US20200155788A1

    公开(公告)日：2020-05-21

    申请号：US16750507

    申请日：2020-01-23

    Applicant: Stamford Devices Limited

    Inventor： Ronan MACLOUGHLIN ,  Niall Smith

    IPC: A61M16/16 ,  A61M16/08 ,  A61M16/10 ,  A61M16/20 ,  A61M16/06 ,  A61M11/00 ,  A61M16/14 ,  A61M15/08

    Abstract: A high flow nasal therapy system (1) has a gas supply (2), a nebulizer (12), and a nasal interface (7). There are two branches (11, 10) and a valve (6) linked with the controller, the branches including a first branch (11) for delivery of aerosol and a second branch (10) for delivery of non-aerosolized gas. The controller controls delivery into the branches (11, 10), in which flow is unidirectional in the first and second branches, from the gas supply towards the nasal interface. The first branch (11) includes the nebulizer (12) and a line configured to store a bolus of aerosol during flow through the second branch (10). The valve (6) comprises a Y-junction between the gas inlet on one side and the branches on the other side.

    END-OF-DOSE DETECTION IN NEBULIZERS
    33.
    发明申请
    END-OF-DOSE DETECTION IN NEBULIZERS 审中-公开

    公开(公告)号：US20180256829A1

    公开(公告)日：2018-09-13

    申请号：US15762387

    申请日：2016-09-22

    Applicant: Stamford Devices Limited

    Inventor： Joseph GREHAN ,  Michael CASEY ,  Shaun PORTER ,  Niall SMITH

    IPC: A61M11/00

    Abstract: A digital processor of a nebulizer controller controls and monitors drive current (I) applied to an aperture plate. The drive current is detected as a series of discrete values at each of multiple measuring points, each having a particular drive frequency The processor in real time calculates a slope or rate of change of drive current with frequency and additionally determines a minimum value for drive current leading up to the peak value. The processor uses both the value of the minimum drive current during the scan and also the maximum slope value to achieve reliable prediction of end of dose, when the aperture plate becomes dry.

    METHOD OF PRODUCING AN APERTURE PLATE FOR A NEBULIZER
    35.
    发明申请
    METHOD OF PRODUCING AN APERTURE PLATE FOR A NEBULIZER 审中-公开
    生产用于网络的孔板的方法

    公开(公告)号：US20150101596A1

    公开(公告)日：2015-04-16

    申请号：US14401480

    申请日：2013-05-24

    Applicant: Stamford Devices Limited

    Inventor： Brendan Hogan

    IPC: A61M11/00 ,  C25D7/00

    Abstract: A photo-resist (21) is applied in a pattern of vertical columns having the dimensions of holes or pores of the aperture plate to be produced. This mask pattern provides the apertures which define the aerosol particle size, having up to 2500 holes per square mm. There is electro-deposition of metal (22) into the spaces around the columns (21). There is further application of a second photo-resist mask (25) of much larger (wider and taller) columns, encompassing the area of a number of first columns (21). The hole diameter in the second plating layer is chosen according to a desired flow rate.

    Abstract translation: 光刻胶（21）以要制造的孔板的孔或孔的尺寸的垂直列的图案施加。 该掩模图形提供限定气溶胶颗粒尺寸的孔，每平方毫米具有多达2500个孔。 将金属（22）电沉积到柱（21）周围的空间中。 进一步应用包括多个第一列（21）的区域的更大（更宽和更高）的列的第二光刻胶掩模（25）。 根据期望的流速选择第二镀层中的孔直径。

    Nebuliser system
    36.
    发明授权
    Nebuliser system 有权
    喷雾器系统

    公开(公告)号：US08517010B2

    公开(公告)日：2013-08-27

    申请号：US12568409

    申请日：2009-09-28

    Applicant: John Sylvester Power ,  Conor Paul Duffy ,  Niall Smith ,  Dermot Clancy ,  Kiernan Hyland

    Inventor： John Sylvester Power ,  Conor Paul Duffy ,  Niall Smith ,  Dermot Clancy ,  Kiernan Hyland

    IPC: A61M11/00

    CPC classification number: A61M11/005 ,  A61M15/0028 ,  A61M15/003 ,  A61M15/0031 ,  A61M15/0035 ,  A61M15/0085 ,  A61M2205/6045 ,  B05B12/081 ,  B05B17/0646

    Abstract: A nebulizer 1 particularly for home use includes a housing 2 having an aerosol generator 3 mounted therein. The housing is closed by a hinged cap 4 and has an outlet 5 through which aerosol generated by the generator 3 is delivered. A suitable connector such as a mouthpiece 6 may be connected to the outlet 5. The housing 2 has a receiver for receiving a nebule 8. The receiver includes a slot 7 which is sized and/or shaped to accommodate only a nebule 8 of predetermined shape and/or size. The nebulizer cap 4 has a nebule opening device which may be in the form of a puncture pin 10 projecting therefrom to pierce the nebule 8 when the cap is moved to the closed position. The pin 10 is hollow or splined to regulate flow from the nebule. The nebulizer 1 also has a switch device for enabling operation of the aerosol generator 3 when the nebule 8 is opened. The switch device comprises a microswitch 12 on the housing which is engageable by a trigger 13 on the cap 4 when the cap is moved to the closed position. Aerosol generated by the aerosol generator 3 is delivered into a chamber defined by the nebulizer housing 2. Air passes into the chamber through air inlets 30. The air entrains the aerosolized medicament and the entrained aerosolized medicament is delivered from the nebulizer through the outlet 5.

    Abstract translation: 特别用于家庭使用的喷雾器1包括具有安装在其中的气溶胶发生器3的壳体2。 壳体由铰接盖4封闭，并且具有出口5，由发生器3产生的气雾通过该出口5被输送。 诸如接口管6的合适的连接器可以连接到出口5.壳体2具有用于接收氖灯8的接收器。接收器包括狭槽7，狭槽7的尺寸和/或形状仅适合于预定形状的氖8 和/或尺寸。 雾化器盖4具有氖开口装置，其可以是当帽移动到关闭位置时从其突出的穿刺销10的形式刺穿氖8。 销10是中空的或花键的，以调节来自星云的流动。 雾化器1还具有开关装置，用于当打开氖8时能够使气溶胶发生器3工作。 开关装置包括壳体上的微型开关12，当盖子移动到关闭位置时，该开关装置可由盖子4上的触发器13接合。 由气溶胶发生器3产生的气溶胶被输送到由喷雾器壳体2限定的室中。空气通过空气入口30进入室。空气携带雾化的药剂，并且夹带的雾化药物从喷雾器通过出口5输送。

    Supplemental oxygen delivery system
    37.
    发明授权
    Supplemental oxygen delivery system 有权
    辅助输氧系统

    公开(公告)号：US08418690B2

    公开(公告)日：2013-04-16

    申请号：US12568399

    申请日：2009-09-28

    Applicant: John Sylvester Power ,  James B. Fink ,  Conor Paul Duffy ,  Trevor Stephen Fahy

    Inventor： John Sylvester Power ,  James B. Fink ,  Conor Paul Duffy ,  Trevor Stephen Fahy

    IPC: A61M11/00

    CPC classification number: A61M16/14 ,  A61M11/002 ,  A61M11/003 ,  A61M11/005 ,  A61M15/0085 ,  A61M16/0057 ,  A61M16/0666 ,  A61M16/0672 ,  A61M16/0833 ,  A61M16/0875 ,  A61M16/147 ,  A61M16/16 ,  A61M2202/0208 ,  A61M2206/14 ,  B05B12/081 ,  B05B17/0646 ,  B05B17/0669

    Abstract: A supplemental oxygen delivery system is described in which Aerosol is delivered into a housing 10, 20, which sits in the circuit from the supplemental oxygen supply and optional humidifier. The supplemental oxygen passes through this chamber 10, 20 in which the aerosol is located, and collects the aerosol transporting it to a patient via a nasal cannula 3 or a face mask 4. An aerosol generator 9 is mounted to the housing 10, 20 and delivers aerosol into an oxygen stream 13 flowing between an inlet 14 and an outlet 15 of the housing 10. The housing 10 also has a removable plug 16 in the base 17 thereof for draining any liquid that accumulates in the housing 10. There is no disruption of oxygen delivery to patients using nasal cannulas who currently have to use a separate face-mask when receiving nebulized medication.

    Abstract translation: 描述了补充氧气输送系统，其中气溶胶被输送到壳体10,20中，壳体10,20从补充氧气供应和可选的加湿器位于电路中。 补充的氧通过其中所述气溶胶所在的腔室10,20，并收集通过鼻插管3或面罩4将其运送到患者的气溶胶。气溶胶发生器9安装到壳体10,20上， 将气溶胶递送到在壳体10的入口14和出口15之间流动的氧气流13.壳体10还具有在其底部17中的可移除的塞子16，用于排出积聚在壳体10中的任何液体。不存在中断 使用鼻塞的患者的氧气输送，当接受雾化药物时，目前必须使用单独的面罩。

    A NEBULIZER WITH PLUME DETECTION
    39.
    发明申请
    A NEBULIZER WITH PLUME DETECTION 有权

    公开(公告)号：US20250058059A1

    公开(公告)日：2025-02-20

    申请号：US18720321

    申请日：2022-11-30

    Applicant: STAMFORD DEVICES LIMITED

    Inventor： Joseph GREHAN ,  Aidan DUFFY ,  Anthony REDMOND

    IPC: A61M11/00

    Abstract: A nebulizer (1, 102) has a liquid reservoir (3, 112) for supply of liquid to be aerosolized to a first surface of a vibratable aperture plate (41) with apertures having a size in the range of 1 pm to 10 pm. A drive has a piezoelectric annular element on an aperture plate support to cause the aperture plate to vibrate at a drive frequency of 128 kHz to cause droplets to separate from a side of the aperture plate opposed to the reservoir. An outlet conduit (6, 114) is for flow of droplets from the aperture plate. A sensor is arranged with an acoustic transducer in contact with the conduit outer surface to pick up an acoustic signal which is representative of a droplet plume in the conduit, and a processor analyses the signal to provide an output representative of a plume. The monitored acoustic signal frequency band is centred around half of the drive frequency because it takes on average more than one aperture plate cycle to separate a droplet.

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