公开(公告)号：US09950092B2

公开(公告)日：2018-04-24

申请号：US15199150

申请日：2016-06-30

Applicant: Allergan, Inc.

Inventor： Gabriel N. Njikang ,  Xiaojie Yu ,  Futian Liu ,  Sumit Paliwal ,  Nicholas J. Manesis

IPC: A61K8/73 ,  A61K8/33 ,  A61Q19/08 ,  A61L27/20 ,  A61L27/54

CPC classification number: A61L27/20 ,  A61K8/33 ,  A61K8/73 ,  A61K8/735 ,  A61K2800/262 ,  A61K2800/95 ,  A61L27/54 ,  A61L2300/402 ,  A61L2400/06 ,  A61Q19/08 ,  C08L5/08

Abstract: The present invention provides highly injectable, long-lasting hyaluronic acid-based hydrogel dermal filler compositions which are particularly advantageous for correction of fine lines in the face.

公开(公告)号：US20170174858A1

公开(公告)日：2017-06-22

申请号：US15454901

申请日：2017-03-09

Applicant: Allergan, Inc.

Inventor： Futian Liu ,  Nicholas J. Manesis ,  Xiaojie Yu ,  Athene Wan Chie Chan

IPC: C08J9/26 ,  A61L31/14 ,  A61L31/06 ,  B01D39/16 ,  B05D5/00 ,  B05D1/38 ,  B05D3/00 ,  C09D171/02 ,  C09D167/04

CPC classification number: C08J9/26 ,  A61L27/56 ,  A61L31/06 ,  A61L31/146 ,  A61L2400/08 ,  B01D39/1692 ,  B01D2239/1208 ,  B01D2239/1216 ,  B05D1/38 ,  B05D3/007 ,  B05D5/00 ,  C08J2201/04 ,  C08J2201/042 ,  C08J2201/0422 ,  C08J2201/0462 ,  C08J2201/0464 ,  C08J2201/05 ,  C08J2205/05 ,  C08J2207/10 ,  C08J2207/12 ,  C08J2325/10 ,  C08J2353/02 ,  C08J2375/04 ,  C08J2383/04 ,  C09D167/04 ,  C09D171/02

Abstract: Provided are porogen compositions and methods of using such porogen compositions in the manufacture of porous materials, for example, porous silicone elastomers. The porogens generally include comprising a core material and shell material different from the core material. The porogens can be used to form a scaffold for making a resulting porous elastomer when the scaffold is removed.

公开(公告)号：US09522502B2

公开(公告)日：2016-12-20

申请号：US14512839

申请日：2014-10-13

Applicant: Allergan, Inc.

Inventor： Futian Liu ,  Nicholas J. Manesis ,  Alexei Goraltchouk ,  Dimitrios Stroumpoulis

IPC: B29C67/20 ,  C08J9/26 ,  A61K47/34 ,  A61L26/00 ,  B29K67/00 ,  B29K83/00 ,  B29K105/00 ,  B29L31/00

CPC classification number: B29C67/202 ,  A61K47/34 ,  A61L26/0019 ,  B29K2067/04 ,  B29K2083/005 ,  B29K2105/0085 ,  B29L2031/753 ,  C08J9/26 ,  C08J2201/0462 ,  C08J2383/04 ,  Y10T428/249921

Abstract: The present specification discloses porous materials, methods of forming such porous materials, materials and devices comprising such porous materials, and methods of making such materials and devices.

公开(公告)号：US20160151542A1

公开(公告)日：2016-06-02

申请号：US14960075

申请日：2015-12-04

Applicant: Allergan, Inc.

Inventor： Futian Liu ,  Nicholas J. Manesis ,  Xiaojie Yu ,  Athene W. Chan

IPC: A61L27/56 ,  A61L27/34 ,  A61L31/14 ,  A61L27/18 ,  A61L31/04 ,  A61L31/06 ,  A61L27/26 ,  A61L27/20 ,  A61L31/10

Abstract: The present specification discloses porogen compositions comprising a core material and shell material, methods of making such porogen compositions, methods of forming such porous materials using such porogen compositions, biocompatible implantable devices comprising such porous materials, and methods of making such biocompatible implantable devices.

公开(公告)号：US20150352251A1

公开(公告)日：2015-12-10

申请号：US14829201

申请日：2015-08-18

Applicant: Allergan, Inc.

Inventor： Futian Liu ,  Xiaojie Yu ,  Nicholas J. Manesis ,  Athene Wan Chie Chan

IPC: A61L27/20 ,  A61L27/58 ,  A61L27/52 ,  A61L27/50 ,  A61L27/54

CPC classification number: A61L27/20 ,  A61K8/042 ,  A61K8/676 ,  A61K8/735 ,  A61K47/60 ,  A61K47/61 ,  A61K2800/91 ,  A61L27/00 ,  A61L27/50 ,  A61L27/52 ,  A61L27/54 ,  A61L27/58 ,  A61L2300/204 ,  A61L2300/402 ,  A61L2400/06 ,  A61Q19/08 ,  C08B37/0072

Abstract: Provided are injectable, hyaluronic acid-based hydrogel compositions including conjugated vitamins.

Abstract translation: 提供可注射的透明质酸基水凝胶组合物，包括缀合的维生素。

公开(公告)号：US20140154508A1

公开(公告)日：2014-06-05

申请号：US14174299

申请日：2014-02-06

Applicant: Allergan, Inc.

Inventor： Futian Liu ,  Nicholas J. Manesis ,  Xiaojie Yu ,  Athene Wan Chie Chan

IPC: A61L31/10

CPC classification number: A61L31/10 ,  A61F2/12 ,  A61L27/16 ,  A61L27/18 ,  A61L27/50 ,  A61L27/56 ,  A61L27/58 ,  A61L2430/04 ,  Y10T428/2989 ,  C08L83/04 ,  C08L23/22 ,  C08L53/02

Abstract: The present specification discloses porogen compositions comprising a core material and shell material, methods of making such porogen compositions, methods of forming such porous materials using such porogen compositions, biocompatible implantable devices comprising such porous materials, and methods of making such biocompatible implantable devices.

Abstract translation: 本说明书公开了包含核心材料和壳材料的致孔剂组合物，制备这种致孔剂组合物的方法，使用这种致孔剂组合物形成这种多孔材料的方法，包含这种多孔材料的生物相容性可植入装置以及制备这种生物相容性可植入装置的方法。

公开(公告)号：US20140094433A1

公开(公告)日：2014-04-03

申请号：US14043632

申请日：2013-10-01

Applicant: Allergan, Inc.

Inventor： Futian Liu ,  Xiaojie Yu ,  Nicholas J. Manesis

IPC: A61K8/73 ,  A61Q19/08 ,  A61K8/67

CPC classification number: A61K8/738 ,  A61K8/671 ,  A61K8/735 ,  A61K2800/56 ,  A61Q19/00 ,  A61Q19/08

Abstract: Compositions, such as hydrogel compositions, that include a hyaluronic acid, a vitamin A, and a cyclodextrin may be used as medical or cosmetic fillers, implants, or creams. For example, the compositions may be used as dermal fillers.

Abstract translation: 可以使用包含透明质酸，维生素A和环糊精的组合物，例如水凝胶组合物作为医疗或化妆品填充剂，植入物或霜剂。 例如，组合物可以用作皮肤填充剂。

公开(公告)号：US20240350706A1

公开(公告)日：2024-10-24

申请号：US18527616

申请日：2023-12-04

Applicant: Allergan, Inc.

Inventor： Xiaojie Yu ,  Nicholas J. Manesis ,  Jacob Pollock

IPC: A61L27/24 ,  A61K8/04 ,  A61K8/73 ,  A61L27/26 ,  A61L27/36 ,  A61L27/52 ,  A61Q19/08

CPC classification number: A61L27/24 ,  A61K8/042 ,  A61K8/735 ,  A61L27/26 ,  A61L27/3695 ,  A61L27/52 ,  A61Q19/08 ,  A61K2800/91 ,  A61L2400/06 ,  A61L2430/34

Abstract: Hydrogels comprising a macromolecular matrix and water may be used for aesthetic fillers, for example, dermal fillers. The macromolecular matrix may include a crosslinked combination of hyaluronic acid and collagen.

公开(公告)号：US10391199B2

公开(公告)日：2019-08-27

申请号：US14842569

申请日：2015-09-01

Applicant: Allergan, Inc.

Inventor： Futian Liu ,  Nicholas J. Manesis ,  Alexei Goraltchouk ,  Dimitri Stroumpoulis

IPC: A61F2/12 ,  A61L27/18 ,  B29C41/14 ,  A61L27/50 ,  A61L27/56 ,  A61L27/58

Abstract: The present specification discloses porous materials, methods of forming such porous materials, biocompatible implantable devices comprising such porous materials, and methods of making such biocompatible implantable devices.

公开(公告)号：US10154951B2

公开(公告)日：2018-12-18

申请号：US15244587

申请日：2016-08-23

Applicant: Allergan, Inc.

Inventor： Elizabeta Pavlovic ,  Monica A. Serban ,  Xiaojie Yu ,  Nicholas J. Manesis

IPC: A61K8/64 ,  A61Q19/08 ,  A61L27/20 ,  A61L27/36 ,  A61L27/52 ,  C08L5/08 ,  A61L27/22 ,  C08J3/075 ,  C08L89/00 ,  C08B37/08 ,  C08H1/00 ,  C08J3/24 ,  A61K8/73

Abstract: Compositions useful as dermal fillers and methods using such compositions to treat various skin and soft tissue conditions. The dermal fillers can comprise silk attached to hyaluronic acid using for example two cross linkers and can be used to treat of facial imperfections, facial defects, facial augmentations, breast imperfections, breast augmentations or breast reconstructions.