摘要:
Novel biaromatic compounds having the following structural formula (I): are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine, in particular in dermatology as well as in the fields of cardiovascular diseases, immune diseases and/or diseases related to the metabolism of lipids, or, alternatively, into cosmetic compositions.
摘要:
Novel polycyclic compounds having the structural formula (I) below: are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively, into cosmetic compositions.
摘要:
There is disclosed an improved differential amplifier (20) having a feedback loop that generates an amplified output signal (Vout) from an input signal (Vin) supplied by a preceding stage. It comprises an input matching circuit (11) connected to said preceding stage, a buffer (22) and an amplification section (12) connected in series in the direct amplification line, a first amplifier (16), a RC network (17′) and a second amplifier (23) connected in series in a parallel loop between the outputs and the inputs of the amplification section that generate the feedback signal. The role of said buffer and second amplifier associated in a dedicated direct and feedback signal combining block (21) is to respectively isolate the input signal and the feedback signal from the summing nodes (A′,B′) at the amplification section inputs. As a result, the summation of the input signal and the feedback signal is improved, the DC component of the output signal is filtered out in order to significantly reduce the DC offset. In addition, the input impedance matching represented by parameter S11 is considerably improved.
摘要:
A test circuit applicable to chips having embedded arrays intermixed with logic is described. Depending on a control signal, the test circuit connects or isolates the arrays to and from the logic. The test circuit operates as a switch placed between the power supply rail of the logic and the power supply rail of the arrays. All input gates are cross-connected to the power supply rail of the logic, and each output gate is connected to the corresponding power supply rail of the arrays. During TEST mode, the control signal turns off the test circuit, cutting off the arrays. The logic is tested while the memory cells remain unselected. Faulty chips are rejected. When the value of the control signal is inverted, a control gate connects all the power supply rails of the arrays to the power supply rail of the logic. The test sequence for the embedded array is then applied. Faulty memory cells are replaced with repairable ones; otherwise, the faulty chips are rejected. Thus, the manufacturing yield of the mixed chips is improved.
摘要:
A slip-casting system utilizing a ceramic powder for the mold. The system facilitates casting thin-walled and/or long objects without additives for demolding.
摘要:
Novel biaromatic compounds having the following structural formula (I): are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine, in particular in dermatology as well as in the fields of cardiovascular diseases, immune diseases and/or diseases related to the metabolism of lipids, or, alternatively, into cosmetic compositions.
摘要:
Novel biaromatic compounds having the structural formula (I) below: are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively, into cosmetic compositions.
摘要:
The use of an enzyme as a research tool for acne, by identifying a compound for the treatment of acne and/or any disorder associated with cutaneous hyperseborrhoea.
摘要:
An in vitro method for screening candidate compounds for the preventive or curative treatment of acne, includes the determination of the capacity of a compound to modulate the expression or the activity of ELOVL5 and the use of modulators of the expression or activity of this enzyme for the treatment of acne or skin disorders associated with a hyperseborrhea; methods for the in vitro diagnosis or prognosis of these pathologies are also described.
摘要:
An in vitro method for screening candidate compounds for the preventive or curative treatment of acne, includes the determination of the capacity of a compound to modulate the expression or the activity of the peroxisome membrane transporter 1 comprising a type 3 ATP-binding site of the sub-family D (ABCD3), and the use of modulators of the expression or activity of this transporter for the treatment of acne or skin disorders associated with a hyperseborrhea; methods for the in vitro diagnosis or prognosis of these pathologies are also described.