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    APPARATUS AND METHOD FOR UTILIZATION OF A HIGH-SPEED OPTICAL WAVELENGTH TUNING SOURCE
    33.
    发明申请
    APPARATUS AND METHOD FOR UTILIZATION OF A HIGH-SPEED OPTICAL WAVELENGTH TUNING SOURCE 有权
    高速光波导调谐源的利用方法及方法

    公开(公告)号：US20100254415A1

    公开(公告)日：2010-10-07

    申请号：US12700552

    申请日：2010-02-04

    申请人： Wang-Yuhl Oh ,  Benjamin J. Vakoc ,  Guillermo J. Tearney ,  Brett E. Bouma

    发明人： Wang-Yuhl Oh ,  Benjamin J. Vakoc ,  Guillermo J. Tearney ,  Brett E. Bouma

    IPC分类号： H01S3/10 ,  G21G4/00

    CPC分类号： H01S3/08009 ,  G01J3/10 ,  H01S3/08013 ,  H01S3/08059 ,  H01S3/0813 ,  H01S3/083 ,  H01S3/105 ,  H01S5/005 ,  H01S5/06216 ,  H01S5/141

    摘要： Exemplary embodiments of apparatus, source arrangement and method for, e.g., providing high-speed wavelength tuning can be provided. According to one exemplary embodiment, at least one arrangement can be provided which is configured to emit an electromagnetic radiation that (i) has a spectrum whose mean frequency changes at an absolute rate that is greater than about 6000 (or 2000) terahertz per millisecond, (ii) whose mean frequency changes over a range that is greater than about 10 terahertz, and/or (iii) has an instantaneous line width that is less than about 15 gigahertz. According to another exemplary embodiment, at least one arrangement can be provided configured to, periodically and as a function of time, select at least one first electro-magnetic radiation based on a mean frequency of the at least one first electro-magnetic radiation, with the periodic selection being performed at a first characteristic period. The mean frequency can vary linearly over time, wherein the apparatus can emit at least one second electromagnetic radiation that has a spectrum whose mean frequency changes periodically as a function of time with a second characteristic period. Further, the first characteristic period can be greater than the second characteristic period.

    摘要翻译： 可以提供用于例如提供高速波长调谐的装置，源装置和方法的示例性实施例。 根据一个示例性实施例，可以提供至少一种布置，其被配置为发射电磁辐射，其中（i）具有平均频率以大于每毫秒大约6000（或2000）太赫兹的绝对速率变化的频谱， （ii）其平均频率在大于约10太赫兹的范围内变化，和/或（iii）具有小于约15千兆赫兹的瞬时线宽。 根据另一示例性实施例，可以提供至少一种布置，其被配置为周期性地和作为时间的函数，基于所述至少一个第一电磁辐射的平均频率选择至少一个第一电磁辐射， 在第一特征周期执行周期性选择。 平均频率可以随时间线性变化，其中该装置可以发射至少一个第二电磁辐射，其具有在第二特征周期内平均频率作为时间的函数周期性地改变的频谱。 此外，第一特征周期可以大于第二特征周期。

    System and method for identifying tissue using low-coherence interferometry
    34.
    发明授权
    System and method for identifying tissue using low-coherence interferometry 有权
    使用低相干干涉法识别组织的系统和方法

    公开(公告)号：US07761139B2

    公开(公告)日：2010-07-20

    申请号：US10765430

    申请日：2004-01-26

    申请人： Guillermo J. Tearney ,  Milen Stefanov Shishkov ,  Nicusor V. Iftimia ,  Brett E. Bouma ,  Martha Pitman

    发明人： Guillermo J. Tearney ,  Milen Stefanov Shishkov ,  Nicusor V. Iftimia ,  Brett E. Bouma ,  Martha Pitman

    IPC分类号： A61B5/00

    CPC分类号： A61B5/6852 ,  A61B5/0066 ,  A61B5/415 ,  A61B5/416 ,  A61B5/418 ,  A61B5/6848

    摘要： An apparatus for needle biopsy with real time tissue differentiation using one dimensional interferometric ranging imaging, comprising a biopsy device having a barrel and a needle, an optical fiber inserted in the needle, and a fiber optic imaging system connected to the optical fiber. The imaging system obtains images and compares the optical properties and patterns to a database of normalized tissue sample images to determine different tissue types. The physician performing the biopsy obtains feedback via a feedback unit associated with the biopsy device and which is connected to the imaging system. The feedback unit can provide visual, audible or vibratory feedback as to tissue type encountered when the needle is inserted toward the target tissue. The feedback unit can be programmed for different biopsy procedures so that the user can actuate a button to select a display or other feedback mechanism for the desired procedure and anticipated tissue to be encountered.

    摘要翻译： 一种使用一维干涉测量成像的实时组织分化的针活检装置，包括具有镜筒和针的活检装置，插入针中的光纤以及连接到光纤的光纤成像系统。 成像系统获得图像并将光学性质和图案与标准化组织样本图像的数据库进行比较，以确定不同的组织类型。 执行活组织检查的医师通过与活检装置相关联的反馈单元获得反馈，并且连接到成像系统。 反馈单元可以提供关于当针朝向目标组织插入时遇到的组织类型的视觉，听觉或振动反馈。 反馈单元可以被编程用于不同的活检程序，使得用户可以致动按钮以选择用于期望的程序和所期望的组织的显示器或其他反馈机构。

    Microscope objectives
    35.
    发明授权
    Microscope objectives 失效
    显微镜目标

    公开(公告)号：US07684134B2

    公开(公告)日：2010-03-23

    申请号：US10542966

    申请日：2004-01-21

    申请人： Guillermo J. Tearney ,  Constantinos Pitris ,  Milen Shishkov ,  Brett E. Bouma

    发明人： Guillermo J. Tearney ,  Constantinos Pitris ,  Milen Shishkov ,  Brett E. Bouma

    IPC分类号： G02B7/02

    CPC分类号： G02B21/0072 ,  G02B21/006 ,  G02B21/02 ,  G02B21/33

    摘要： A confocal microscope lens arrangement is provided. The confocal microscope lens arrangement includes a lens assembly housing which has a lens assembly, and an exterior housing including a distal end and a proximal end. The exterior housing is configured to allow the lens assembly housing to be placed therein, and translated between the proximal end and the distal end of the exterior housing to focus the lens assembly. The exterior housing has an aperture formed through a distal end thereof. The arrangement also includes an immersion media filling the volume of area between the exterior housing and the lens assembly housing.

    摘要翻译： 提供共焦显微镜透镜装置。 共焦显微镜透镜装置包括具有透镜组件的透镜组件壳体和包括远端和近端的外壳。 外部壳体被配置为允许透镜组件壳体放置在其中并且在外部壳体的近端和远端之间平移以聚焦透镜组件。 外壳具有通过其远端形成的孔。 该布置还包括填充外壳和透镜组件壳体之间的面积的浸没介质。

    SYSTEMS AND METHODS FOR PROVIDING MIRROR TUNNEL MICROPSCOPY
    38.
    发明申请
    SYSTEMS AND METHODS FOR PROVIDING MIRROR TUNNEL MICROPSCOPY 审中-公开
    用于提供微波隧道微波的系统和方法

    公开(公告)号：US20070171430A1

    公开(公告)日：2007-07-26

    申请号：US11624601

    申请日：2007-01-18

    申请人： Guillermo J. Tearney ,  Brett E. Bouma ,  Aydogan Ozcan

    发明人： Guillermo J. Tearney ,  Brett E. Bouma ,  Aydogan Ozcan

    IPC分类号： G01B11/02

    CPC分类号： G02B27/08 ,  G01J3/36 ,  G02B17/006 ,  G02B21/00 ,  G02B21/367 ,  G02B27/46

    摘要： Exemplary apparatus and method for obtaining information associated with at least one image of at least one portion of a sample can be provided. For example, at least one first electro-magnetic radiation can be provided from the at least one portion (e.g., using a first electro-magnetic radiation guiding arrangement which is configured to provide). A plurality of spatial frequency bands of the image associated with the first electro-magnetic radiation can be generated. Further, at least one second electro-magnetic radiation which is associated with the spatial frequency bands of the image can be received (e.g., using a second arrangement), and the image can be reconstructed based on the spatial frequency bands.

    摘要翻译： 可以提供用于获得与样品的至少一部分的至少一个图像相关联的信息的示例性装置和方法。 例如，可以从至少一个部分（例如，使用配置为提供的第一电磁辐射引导装置）提供至少一个第一电磁辐射。 可以产生与第一电磁辐射相关联的图像的多个空间频带。 此外，可以接收与图像的空间频带相关联的至少一个第二电磁辐射（例如，使用第二布置），并且可以基于空间频带重建图像。