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    System and method for identifying tissue using low-coherence interferometry
    1.
    发明授权
    System and method for identifying tissue using low-coherence interferometry 有权
    使用低相干干涉法识别组织的系统和方法

    公开(公告)号：US07761139B2

    公开(公告)日：2010-07-20

    申请号：US10765430

    申请日：2004-01-26

    申请人： Guillermo J. Tearney ,  Milen Stefanov Shishkov ,  Nicusor V. Iftimia ,  Brett E. Bouma ,  Martha Pitman

    发明人： Guillermo J. Tearney ,  Milen Stefanov Shishkov ,  Nicusor V. Iftimia ,  Brett E. Bouma ,  Martha Pitman

    IPC分类号： A61B5/00

    CPC分类号： A61B5/6852 ,  A61B5/0066 ,  A61B5/415 ,  A61B5/416 ,  A61B5/418 ,  A61B5/6848

    摘要： An apparatus for needle biopsy with real time tissue differentiation using one dimensional interferometric ranging imaging, comprising a biopsy device having a barrel and a needle, an optical fiber inserted in the needle, and a fiber optic imaging system connected to the optical fiber. The imaging system obtains images and compares the optical properties and patterns to a database of normalized tissue sample images to determine different tissue types. The physician performing the biopsy obtains feedback via a feedback unit associated with the biopsy device and which is connected to the imaging system. The feedback unit can provide visual, audible or vibratory feedback as to tissue type encountered when the needle is inserted toward the target tissue. The feedback unit can be programmed for different biopsy procedures so that the user can actuate a button to select a display or other feedback mechanism for the desired procedure and anticipated tissue to be encountered.

    摘要翻译： 一种使用一维干涉测量成像的实时组织分化的针活检装置，包括具有镜筒和针的活检装置，插入针中的光纤以及连接到光纤的光纤成像系统。 成像系统获得图像并将光学性质和图案与标准化组织样本图像的数据库进行比较，以确定不同的组织类型。 执行活组织检查的医师通过与活检装置相关联的反馈单元获得反馈，并且连接到成像系统。 反馈单元可以提供关于当针朝向目标组织插入时遇到的组织类型的视觉，听觉或振动反馈。 反馈单元可以被编程用于不同的活检程序，使得用户可以致动按钮以选择用于期望的程序和所期望的组织的显示器或其他反馈机构。

    System and Method for Identifying Tissue Using Low-Coherence Interferometry
    2.
    发明申请
    System and Method for Identifying Tissue Using Low-Coherence Interferometry 审中-公开
    使用低相干干涉法识别组织的系统和方法

    公开(公告)号：US20110092823A1

    公开(公告)日：2011-04-21

    申请号：US12839165

    申请日：2010-07-19

    申请人： Guillermo J. Tearney ,  Milen Stefanov Shishkov ,  Nicursor V. Iftimia ,  Brett E. Bouma ,  Martha Pitman

    发明人： Guillermo J. Tearney ,  Milen Stefanov Shishkov ,  Nicursor V. Iftimia ,  Brett E. Bouma ,  Martha Pitman

    IPC分类号： A61B6/00

    CPC分类号： A61B5/6852 ,  A61B5/0066 ,  A61B5/415 ,  A61B5/416 ,  A61B5/418 ,  A61B5/6848

    摘要： An apparatus for needle biopsy with real time tissue differentiation using one dimensional interferometric ranging imaging, comprising a biopsy device having a barrel and a needle, an optical fiber inserted in the needle, and a fiber optic imaging system connected to the optical fiber. The imaging system obtains images and compares the optical properties and patterns to a database of normalized tissue sample images to determine different tissue types. The physician performing the biopsy obtains feedback via a feedback unit associated with the biopsy device and which is connected to the imaging system. The feedback unit can provide visual, audible or vibratory feedback as to tissue type encountered when the needle is inserted toward the target tissue. The feedback unit can be programmed for different biopsy procedures so that the user can actuate a button to select a display or other feedback mechanism for the desired procedure and anticipated tissue to be encountered.

    摘要翻译： 一种使用一维干涉测量成像的实时组织分化的针活检装置，包括具有镜筒和针的活检装置，插入针中的光纤以及连接到光纤的光纤成像系统。 成像系统获得图像并将光学性质和图案与标准化组织样本图像的数据库进行比较，以确定不同的组织类型。 执行活组织检查的医师通过与活检装置相关联的反馈单元获得反馈，并且连接到成像系统。 反馈单元可以提供关于当针朝向目标组织插入时遇到的组织类型的视觉，听觉或振动反馈。 反馈单元可以被编程用于不同的活检程序，使得用户可以致动按钮以选择用于期望的程序和所期望的组织的显示器或其他反馈机构。

    SYSTEMS, METHODS AND COMPUTER-ACCESSIBLE MEDIUM WHICH PROVIDE MICROSCOPIC IMAGES OF AT LEAST ONE ANATOMICAL STRUCTURE AT A PARTICULAR RESOLUTION
    7.
    发明申请
    SYSTEMS, METHODS AND COMPUTER-ACCESSIBLE MEDIUM WHICH PROVIDE MICROSCOPIC IMAGES OF AT LEAST ONE ANATOMICAL STRUCTURE AT A PARTICULAR RESOLUTION 有权
    系统，方法和计算机可访问介质，提供特定解决方案中至少一个解剖结构的微观图像

    公开(公告)号：US20110261366A1

    公开(公告)日：2011-10-27

    申请号：US13042230

    申请日：2011-03-07

    申请人： Guillermo J. Tearney ,  Brett E. Bouma ,  Joseph A. Gardecki ,  Linbo Liu

    发明人： Guillermo J. Tearney ,  Brett E. Bouma ,  Joseph A. Gardecki ,  Linbo Liu

    IPC分类号： G01B9/02

    CPC分类号： A61B5/0066 ,  A61B5/0044 ,  A61B5/0075 ,  A61B5/0084 ,  G01B9/02091 ,  G02B6/32

    摘要： Exemplary embodiments of systems and methods can be provided which can generate data associated with at least one portion of a sample. For example, at least one first radiation can be forwarded to the portion through at least one optical arrangement. At least one second radiation can be received from the portion which is based on the first radiation. Based on an interaction between the optical arrangement and the first radiation and/or the second radiation, the optical arrangement can have a first transfer function. Further, it is possible to forward at least one third radiation to the portion through such optical arrangement (or through another optical arrangement), and receive at least one fourth radiation from the portion which is based on the third radiation. Based on an interaction between the optical arrangement (or the other optical arrangement) and the third radiation and/or the fourth radiation, the optical arrangement (or the other optical arrangement) can have a second transfer function. The first transfer function can be at least partially different from the second transfer function. The data can be generated based on the second and fourth radiations.

    摘要翻译： 可以提供可以生成与样品的至少一部分相关联的数据的系统和方法的示例性实施例。 例如，可以通过至少一个光学布置将至少一个第一辐射转发到该部分。 可以从基于第一辐射的部分接收至少一个第二辐射。 基于光学布置和第一辐射和/或第二辐射之间的相互作用，光学装置可以具有第一传递函数。 此外，可以通过这种光学装置（或通过另一种光学装置）将至少一个第三辐射转发到该部分，并且从基于第三辐射的部分接收至少一个第四辐射。 基于光学布置（或另一个光学布置）与第三辐射和/或第四辐射之间的相互作用，光学布置（或另一个光学布置）可以具有第二传递函数。 第一传递函数可以至少部分地不同于第二传递函数。 可以基于第二和第四辐射来生成数据。