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    Systems and methods for ejection of ions from an ion trap
    33.
    发明授权
    Systems and methods for ejection of ions from an ion trap 有权

    公开(公告)号：US09922813B2

    公开(公告)日：2018-03-20

    申请号：US15421934

    申请日：2017-02-01

    Applicant: Purdue Research Foundation

    Inventor： Robert Graham Cooks ,  Dalton Snyder

    IPC: H01J49/42 ,  H01J49/00

    CPC classification number: H01J49/4285 ,  H01J49/0013 ,  H01J49/4225

    Abstract: The invention generally relates to systems and methods for ejection of ions from an ion trap. In certain embodiments, systems and methods of the invention sum two different frequency signals into a single summed signal that is applied to an ion trap. In other embodiments, an amplitude of a single frequency signal is modulated as the single frequency signal is being applied to the ion trap. In other embodiments, a first alternating current (AC) signal is applied to an ion trap that varies as a function of time, while a constant radio frequency (RF) signal is applied to the ion trap.

    REACTION MONITORING
    34.
    发明申请
    REACTION MONITORING 审中-公开

    公开(公告)号：US20180047552A1

    公开(公告)日：2018-02-15

    申请号：US15672862

    申请日：2017-08-09

    Applicant: Purdue Research Foundation

    Inventor： Robert Graham Cooks ,  Xin Yan ,  Christopher Pulliam ,  Ryan M. Bain ,  Tawnya Flick

    IPC: H01J49/00 ,  H01J49/04 ,  G01N33/68 ,  H01J49/16

    CPC classification number: H01J49/0031 ,  G01N33/6848 ,  H01J49/0409 ,  H01J49/165

    Abstract: The invention generally relates to systems and methods for on-line reaction monitoring. In certain embodiments, the invention provides systems that include a reaction vessel having an outlet, a quantitation unit coupled to the outlet and configured to introduce internal standard and solvent into reaction solution flowed from the reaction vessel, one or more ion generating devices that receive flow from the quantitation unit, and a mass spectrometer. In certain embodiments, the invention provides systems for multiple reaction monitoring that include a plurality of reaction vessels, a plurality of ion generating devices, a plurality of channels, each channel coupling a reaction vessel to an ion generating device, an actuator coupled to the plurality of ion generating devices to thereby allow movement of the plurality of ion generating devices, and a mass spectrometer

    ION FOCUSING
    37.
    发明申请
    ION FOCUSING 有权

    公开(公告)号：US20170287690A1

    公开(公告)日：2017-10-05

    申请号：US15407499

    申请日：2017-01-17

    Applicant: Purdue Research Foundation

    Inventor： Robert Graham Cooks ,  Zane Baird ,  Wen-Ping Peng

    IPC: H01J49/06 ,  H01J49/16 ,  H01J49/10 ,  H01J49/26

    CPC classification number: H01J49/067 ,  H01J49/06 ,  H01J49/10 ,  H01J49/165 ,  H01J49/26

    Abstract: The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives the focused ions and a distal end of the outlet is open to ambient pressure.

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